Drug & supplement interaction

Chirata + Trandolapril, Verapamil

Trandolapril, Verapamil brand name: Tarka.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Chirata and Trandolapril, Verapamil in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Trandolapril, Verapamil states a food rule worth keeping to.

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Interaction report

Chirata and Trandolapril, Verapamil

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Trandolapril, Verapamil and Chirata in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Chirata safety at a glance

Chirata overall Use caution Generally used in small amounts in traditional medicine, but human safety data are limited.
Pregnancy Avoid Not enough safety data; avoid use during pregnancy.
Breastfeeding Avoid Not enough safety data; avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Trandolapril, Verapamil and Chirata? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Trandolapril, Verapamil

Interactions in our licensed database are recorded against drug classes, not just single drug names. Trandolapril, Verapamil is filed under 13 classifications — including calcium channel blockers, ace inhibitors (aceis), cytochrome p450 2c8 (cyp2c8) substrates. Chirata has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Trandolapril, Verapamil’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Chirata Does Interact With Other Medications

Chirata has 86 moderate known drug interactions in our database — Trandolapril, Verapamil isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Trandolapril, Verapamil)
Taking anything else?

Check Another of Your Medications Against Chirata

Covers the 2,830 medications we’ve checked against Chirata. Pick one to open its full report.

What to actually watch for

What Trandolapril, Verapamil’s Own FDA Label Lists

This is not an interaction — none of it involves Chirata. These are the most notable effects listed in the ADVERSE REACTIONS section of Trandolapril, Verapamil’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A stroke or mini-stroke Worth acting on
  • A bowel blockage Worth acting on
  • High potassium Worth acting on
  • Low sodium Worth acting on
  • Unsteadiness Worth acting on
  • A slow heartbeat Worth acting on
  • A heart attack Worth acting on
  • Pancreatitis Worth acting on
  • Fainting Worth acting on
  • Confusion Worth acting on

Showing the 10 most notable of 50 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Trandolapril, Verapamil. Read the label on DailyMed › Chirata’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Chirata side to compare — that is a limit of the record, not a statement that Chirata has no side effects.

How to take them

Some Trandolapril, Verapamil Products Have a Food Rule — Chirata Should Not Break It

At least one FDA label for a product containing Trandolapril, Verapamil says to take it with food. If you take Chirata on an empty stomach out of habit, keep them separate — and take Trandolapril, Verapamil with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Trandolapril, Verapamil products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Trandolapril and verapamil hydrochloride extended-release tablets should be administered with food.

From the Dosage and Administration section of the FDA label we read for Trandolapril, Verapamil — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Trandolapril, Verapamil

This page covers Chirata only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Trandolapril, Verapamil page lists 304 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Beer (major).

By severity: 11 major · 250 moderate · 43 minor.

From our pharmacist’s overview on the Trandolapril, Verapamil page

“This is one of the supplement lists I would want a patient to read closely, not skim. Tarka combines trandolapril and verapamil to lower blood pressure, and most of these interactions pull on that same lever, either dropping pressure further than intended or working against the medicine altogether.”

Reviewed by 2 · Jul 18, 2026

Open the Trandolapril, Verapamil interaction page

One more smart check

Taking Chirata as Part of a Dietary Supplement Product? Check It for Interactions

We hold 26 real supplement products containing Chirata, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Chirata. Even though Chirata itself has no known interaction with Trandolapril, Verapamil, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Chirata and Trandolapril, Verapamil Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chirata
Steady interest

#1,102 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Trandolapril, Verapamil
Top 25%

#517 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Chirata reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Chirata and Trandolapril, Verapamil records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Chirata

What is Chirata?

  • Digestive upset and loss of appetite
  • Fever
  • Blood sugar support
  • Liver health support
  • Skin conditions
  • General 'blood purifier' or tonic

Chirata is a very bitter herb used in traditional Ayurvedic and South Asian medicine, mainly for digestion, fever, and as a general tonic. Human evidence for its benefits is limited, so it should not replace proven treatments, and you should talk to a pharmacist or doctor before using it.

Swertia chirayita · Gentianaceae · Whole plant, especially the dried stems and leaves · Powder, capsules, tablets, water infusion (cold or hot), liquid extract, and traditional herbal blends

An interaction check asks whether these two react with each other — it does not ask whether Chirata is a good idea for someone in your situation. Here is what our Chirata record says about it on its own.

Chirata: dosing

There is no well-established, standardized dose for chirata. The right amount can depend on the form (powder, capsule, or infusion) and the strength of the product.The safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Chirata monograph — the full record covers uses, side effects and every documented interaction.

Read the full Chirata monograph & all interactions
Keep checking

Other Drugs & Chirata

Browse every other medication we’ve checked against Chirata — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Chirata page.

No interaction 2,743 drugs checked — show the list

We also checked Chirata against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Chirata list.

See the full Chirata interactions page
See every supplement checked against Trandolapril, Verapamil, ranked by severity
Evidence & sources

Chirata References

The 1 references that drive our Chirata monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sekar, B. C., Mukherjee, B., Chakravarti, R. B., and Mukherjee, S. K. Effect of different fractions of Swertia chirayita on the blood sugar level of albino rats. J.Ethnopharmacol. 1987;21(2):175-181. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Chirata and Trandolapril, Verapamil Together: Common Questions

Is it safe to take Chirata with Trandolapril, Verapamil?
We do not list a known interaction between Chirata and Trandolapril, Verapamil. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Chirata and Trandolapril, Verapamil at the same time of day?
At least one FDA label for a product containing Trandolapril, Verapamil says to take it with food. If you take Chirata on an empty stomach out of habit, keep them separate and take Trandolapril, Verapamil with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Trandolapril, Verapamil products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Chirata and Trandolapril, Verapamil combination checked?
Interactions in our licensed database are recorded against drug classes. Trandolapril, Verapamil is filed under 13 classifications, and Chirata has documented interactions with 1 drug class — none of Trandolapril, Verapamil's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Chirata interact with any other medications?
Yes. Chirata has 86 documented drug interactions in our database — Trandolapril, Verapamil is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Trandolapril, Verapamil interact with any supplements?
Yes. Trandolapril, Verapamil has documented interactions with 304 supplements in our database — Chirata is not one of them. The Trandolapril, Verapamil interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Chirata monograph Uses, safety profile, and every drug interaction in one place Trandolapril, Verapamil supplement interactions Every supplement checked against Trandolapril, Verapamil, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Trandolapril, Verapamil and Chirata?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.