Drug & supplement interaction

Corn Silk + Ustekinumab

Ustekinumab brand name: Stelara.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Corn Silk and Ustekinumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Corn Silk and Ustekinumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ustekinumab and Corn Silk in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Corn Silk safety at a glance

Corn Silk overall Use caution Generally well tolerated for short-term use, but human safety data are limited.
Pregnancy Avoid Not enough reliable safety data, so it is best avoided during pregnancy.
Breastfeeding Possibly Safe When consumed in food amounts. Insufficient reliable information available when used as medicine; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ustekinumab and Corn Silk? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Ustekinumab

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ustekinumab is filed under a single classification — immunosuppressants. Corn Silk has documented interactions with 5 drug classes — the most serious being antidiabetes drugs (moderate), antihypertensive drugs (moderate) and corticosteroids (moderate) — and none of Ustekinumab’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Corn Silk Does Interact With Other Medications

Corn Silk has 290 moderate known drug interactions in our database — Ustekinumab isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Corn Silk

Covers the 2,830 medications we’ve checked against Corn Silk. Pick one to open its full report.

What to actually watch for

What Corn Silk Itself Has Been Linked To

This is not an interaction — nothing below involves Ustekinumab. It is the side-effect record for Corn Silk on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Corn Silk, this list is the first place to look. 3 entries are worth acting on rather than waiting out — marked below.

  • Low sodium Worth acting on Additional detail

    “Orally, adverse effects to corn silk seem to be rare; however, a thorough safety evaluation has not been conducted.

    Most Common Adverse Effects:

    Orally: Hypokalemia, hyponatremia.”

    Corn Silk · Natural Medicines adverse-effect record, reported in hypokalemia.

  • Low potassium Worth acting on Additional detail

    “Orally, corn silk has been reported to cause hypokalemia with prolonged use (4).”

    Corn Silk · Natural Medicines adverse-effect record, reported in hypokalemia.

    1 source cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  • Hives Worth acting on Additional detail

    “Topically, corn silk can cause dermatitis and urticaria (4).”

    Corn Silk · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  • A skin rash Additional detail

    Recorded for Corn Silk in the same Natural Medicines adverse-effect record shown under Hives above.

Everything above comes from the Natural Medicines adverse-effect record for Corn Silk — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Ustekinumab’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Ustekinumab column appears here.

Special populations

Corn Silk in Pregnancy & Breastfeeding

Lactation Possibly Safe

When consumed in food amounts. Insufficient reliable information available when used as medicine; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Ustekinumab

This page covers Corn Silk only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ustekinumab page lists 53 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Active Hexose Correlated Compound (ahcc) (moderate), Alfalfa (moderate), American Ginseng (moderate), Andrographis (moderate) and Ashwagandha (moderate).

By severity: 52 moderate · 1 minor.

From our pharmacist’s overview on the Ustekinumab page

“Nothing on this page should scare anyone off ustekinumab (Stelara), but the pattern is worth knowing. Stelara treats psoriasis, psoriatic arthritis, and Crohn's disease by quieting part of the immune system, and all 53 supplements here are flagged for the same reason.”

Reviewed by 2 · Jul 18, 2026

Open the Ustekinumab interaction page

One more smart check

Taking Corn Silk as Part of a Dietary Supplement Product? Check It for Interactions

We hold 58 real supplement products containing Corn Silk, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Corn Silk. Even though Corn Silk itself has no known interaction with Ustekinumab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Corn Silk and Ustekinumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Corn Silk
Top half

#368 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ustekinumab
Steady interest

#2,096 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Corn Silk reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Corn Silk and Ustekinumab records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Corn Silk

What is Corn Silk?

Corn Silk
  • Urinary tract and bladder problems
  • Mild fluid retention (diuretic)
  • Kidney and prostate concerns
  • Bedwetting in children
  • Soothing urinary irritation

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should not replace proven treatments. It is generally considered low-risk for short-term use in healthy adults, but talk with your pharmacist or doctor before trying it.

Zea mays · Poaceae · Stigmas and styles (the silky strands) of the corn ear · Tea, dried herb, liquid extract/tincture, capsules

An interaction check asks whether these two react with each other — it does not ask whether Corn Silk is a good idea for someone in your situation. Here is what our Corn Silk record says about it on its own.

Corn Silk: dosing

There is no official, standardized dose for corn silk. It has traditionally been taken as a tea made by steeping dried corn silk in hot water, or as a liquid extract or capsule.Because product strengths vary widely, the best advice is to follow the directions on the product label and not exceed them.

From our Corn Silk monograph — the full record covers uses, side effects and every documented interaction.

Read the full Corn Silk monograph & all interactions
Medication

About Ustekinumab Injection

What Is Ustekinumab Injection Used For?

Brand name: Stelara

Ustekinumab injection treats four immune-related conditions. It is approved for moderate to severe plaque psoriasis and active psoriatic arthritis in adults and children 6 years of age and older. It also treats moderately to severely active Crohn's disease in adults and children 2 years of age and older.

For moderately to severely active ulcerative colitis, ustekinumab injection is approved for adult patients only. A prescriber will determine which condition is being treated and choose the appropriate product, route, and dosing schedule.

See full Ustekinumab Injection drug information
Keep checking

Other Drugs & Corn Silk

Browse every other medication we’ve checked against Corn Silk — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
290Moderate
0Minor
2,539No known interaction
Moderate

290 interactions

Showing 60 of 290 moderate interactions — see all 290 on the Corn Silk page.

No interaction 2,539 drugs checked — show the list
Evidence & sources

Corn Silk References

The 4 references that drive our Corn Silk monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
  4. Sheng L, Chen Q, Di L, Li N. Evaluation of anti-diabetic potential of corn silk in high-fat diet/streptozotocin- induced type 2 diabetes mice model. Endocr Metab Immune Disord Drug Targets. 2020. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Corn Silk and Ustekinumab Together: Common Questions

Is it safe to take Corn Silk with Ustekinumab?
We do not list a known interaction between Corn Silk and Ustekinumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Corn Silk and Ustekinumab combination checked?
Interactions in our licensed database are recorded against drug classes. Ustekinumab is filed under 1 classification, and Corn Silk has documented interactions with 5 drug classes — none of Ustekinumab's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Corn Silk interact with any other medications?
Yes. Corn Silk has 290 documented drug interactions in our database — Ustekinumab is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Ustekinumab interact with any supplements?
Yes. Ustekinumab has documented interactions with 53 supplements in our database — Corn Silk is not one of them. The Ustekinumab interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Ustekinumab and Corn Silk?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.