Genistein Combined Polysaccharide - Amitriptyline, Chlordiazepoxide Interaction
Herbal: Genistein Combined Polysaccharide
Drug: Amitriptyline, Chlordiazepoxide
Brand names:
Limbitrol DS

Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 26, 2023
Interaction Details
Amitriptyline, Chlordiazepoxide is classified as belonging to the following category: Cytochrome P450 2C9 (Cyp2C9) Substrates
Some evidence suggests that genistein can alter the pharmacokinetics of CYP2C9 substrates and should be used cautiously with them. This has only been seen in animal studies however. (PUBMED https://pubmed.ncbi.nlm.nih.gov/29387488/)
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
Genistein Combined Polysaccharide Overview
Genistein Combined Polysaccharide - More Interactions
Genistein Combined Polysaccharide interacts with 138 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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Drug descriptions are provided by MedlinePlus.