Drug & supplement interaction

Yogurt + Levonorgestrel

Levonorgestrel brand names: Plan B, Mirena, Levonelle One Step, Levonelle 1500, Norgeston, and others.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Yogurt and Levonorgestrel in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Yogurt and Levonorgestrel

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Levonorgestrel and Yogurt in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Yogurt safety at a glance

Yogurt overall Generally safe Yogurt is generally safe as a food for most healthy people.
Pregnancy Likely Safe When consumed in amounts commonly found in foods. Read the full pregnancy detail
Breastfeeding Likely Safe When used in amounts commonly found in foods. There is insufficient reliable information available about the safety of the intravaginal use of yogurt during bre... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Levonorgestrel and Yogurt? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Levonorgestrel

Interactions in our licensed database are recorded against drug classes, not just single drug names. Levonorgestrel is filed under 6 classifications — including contraceptive drugs, cytochrome p450 1a2 (cyp1a2) inhibitors, topical drugs. Yogurt has documented interactions with 3 drug classes — the most serious being ciprofloxacin (cipro) (moderate), tetracycline antibiotics (moderate) and nilotinib (tasigna) (minor) — and none of Levonorgestrel’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Yogurt Does Interact With Other Medications

Yogurt has 21 moderate, 1 minor known drug interactions in our database — Levonorgestrel isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Yogurt

Covers the 2,830 medications we’ve checked against Yogurt. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Yogurt and Levonorgestrel May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Hives Worth acting on Additional detail

    Yogurt

    “Orally, patients with milk allergy may be allergic to the protein in yogurt. Symptoms include urticaria, wheezing, cough, and rarely vomiting and diarrhea.

    Fatal Lacticaseibacillus rhamnosus septicemia has been reported in an immunocompromised patient consuming yogurt and taking prolonged courses of multiple broad-spectrum antibiotics.”

    Yogurt · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    2 sources cited
    1. 101751. Küçükosmanoglu E, Özen E, Eltan SB, Özkars MY, Keskin Ö. Most children who are allergic to cow's milk tolerate yogurt. J Int Med Res. 2018;46(12):5099-5106. PubMed
    2. 8561. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed

    Levonorgestrel

    Listed in the ADVERSE REACTIONS section of the FDA label for Levonorgestrel. Read the label on DailyMed ›

  • Stomach pain / Nausea reported in 4.5% of FDA reports for Levonorgestrel Additional detail

    Yogurt

    “Orally, consuming yogurt with or without added probiotics has been reported to cause diarrhea, stomach pain, nausea, and vomiting in clinical research.”

    Yogurt · Natural Medicines adverse-effect record, reported in diarrhea.

    Levonorgestrel

    Listed in the ADVERSE REACTIONS section of the FDA label for Levonorgestrel, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

  • A skin rash Additional detail

    Yogurt

    “Orally, consuming yogurt containing Streptococcus thermophilus, Lactobacillus delbrueckii subsp. bulgaricus, and Bifidobacterium lactis BB-12, 4 ounces daily, has been associated with one report of dermatitis in one clinical trial.”

    Yogurt · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 93707. Merenstein DJ, Smith KH, Scriven M, Roberts RF, Sanders ME, Petterson S. The study to investigate the potential benefits of probiotics in yogurt, a patient-oriented, double-blind, cluster-randomised, placebo-controlled, clinical trial. Eur J Clin Nutr. 20 PubMed

    Levonorgestrel

    Listed in the ADVERSE REACTIONS section of the FDA label for Levonorgestrel. Read the label on DailyMed ›

Reported for Yogurt but not commonly for Levonorgestrel: vomiting, diarrhea, wheezing and cough.

Effects for Levonorgestrel come from the ADVERSE REACTIONS section of its FDA label; effects for Yogurt come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 206,325 voluntary FDA FAERS reports for Levonorgestrel that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Yogurt in Pregnancy & Breastfeeding

Pregnancy Likely Safe

When consumed in amounts commonly found in foods.

Pregnancy Possibly Safe

When used intravaginally. A small clinical study in pregnancy reported no adverse reactions.

Lactation Likely Safe

When used in amounts commonly found in foods. There is insufficient reliable information available about the safety of the intravaginal use of yogurt during breast-feeding.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Yogurt or Levonorgestrel

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Yogurt or Levonorgestrel, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Levonorgestrel

This page covers Yogurt only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Levonorgestrel page lists 191 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 142 moderate · 43 minor.

From our pharmacist’s overview on the Levonorgestrel page

“St. John's wort tops my worry list for anyone using levonorgestrel (Plan B, Mirena, and other birth control).”

Reviewed by 2 · Jul 18, 2026

Open the Levonorgestrel interaction page

One more smart check

Taking Yogurt as Part of a Dietary Supplement Product? Check It for Interactions

We hold 45 real supplement products containing Yogurt, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Yogurt. Even though Yogurt itself has no known interaction with Levonorgestrel, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Yogurt and Levonorgestrel Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Yogurt
Top half

#374 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Levonorgestrel
Top 25%

#471 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Yogurt reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Yogurt and Levonorgestrel records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Yogurt

What is Yogurt?

  • Digestive health
  • Restoring gut bacteria after antibiotics
  • Vaginal yeast or bacterial balance
  • Source of protein and calcium
  • General immune and gut support

Yogurt is a fermented dairy food that often contains live bacteria (probiotics) and provides protein, calcium, and other nutrients. For most healthy people it is a safe, nutritious food, and some yogurts with live cultures may help with digestion and gut balance, though evidence varies by strain and condition. If you are lactose intolerant, have a milk allergy, or have a weakened immune system, talk to your pharmacist or doctor first.

Fermented milk product (made with live bacterial cultures) · Plain yogurt, Greek yogurt, drinkable yogurt (kefir-style), probiotic yogurt, dairy-free yogurt alternatives

An interaction check asks whether these two react with each other — it does not ask whether Yogurt is a good idea for someone in your situation. Here is what our Yogurt record says about it on its own.

Yogurt: dosing

There is no official "dose" for yogurt because it is a food, not a standardized medicine. The amount and type of live bacteria can vary widely from product to product, and many people simply eat one or more servings a day as part of a healthy diet.If you are using yogurt specifically for its probiotic content, look for a label that says "live and active cultures" and check whether the strains are listed. There is no proven "best" amount for any health condition. If you want a specific probiotic strain or dose, a standardized probiotic supplement may be more reliable.

From our Yogurt monograph — the full record covers uses, side effects and every documented interaction.

Read the full Yogurt monograph & all interactions
Medication

About Levonorgestrel

What Is Levonorgestrel Used For?

Brand names: Plan B, Mirena, Levonelle One Step, Levonelle 1500, Norgeston, Skyla, Liletta, Kyleena

Levonorgestrel is used in two very different ways, depending on the product.

The intrauterine systems (Mirena, Liletta, Kyleena and Skyla) prevent pregnancy for a set number of years. Mirena and Liletta are also used to treat heavy menstrual bleeding in women who choose intrauterine contraception. The oral tablets are used for emergency contraception, to reduce the chance of pregnancy after unprotected sex.

Most-Reported Side Effects for Levonorgestrel

From FAERS, the FDA’s public side-effect reporting system (206,325 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Device expulsion 45,536 reports
Device dislocation 20,447 reports
Menstruation irregular 15,061 reports
Vaginal haemorrhage 15,056 reports
Genital haemorrhage 11,164 reports
See full Levonorgestrel drug information
Keep checking

Other Drugs & Yogurt

Browse every other medication we’ve checked against Yogurt — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
21Moderate
1Minor
2,807No known interaction
Moderate

21 interactions

Minor

1 interaction

No interaction 2,807 drugs checked — show the list
Evidence & sources

Yogurt References

The 9 references that drive our Yogurt monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Neri A, Sabah G, Samra Z. Bacterial vaginosis in pregnancy treated with yogurt. Acta Obstet Gynecol Scand 1993;72:17-9.
  3. Neuvonen PJ, Kivisto KT, Lehto P. Interference of dairy products with the absorption of ciprofloxacin. Clin Pharmacol Ther 1991;50:498-502. PubMed
  4. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  5. Liu J, Tang W, Sang L, Dai X, Wei D, Luo Y, Zhang J. Milk, yogurt, and lactose intake and ovarian cancer risk: a meta-analysis. Nutr Cancer. 2015;67(1):68-72. PubMed
  6. Merenstein DJ, Smith KH, Scriven M, Roberts RF, Sanders ME, Petterson S. The study to investigate the potential benefits of probiotics in yogurt, a patient-oriented, double-blind, cluster-randomised, placebo-controlled, clinical trial. Eur J Clin Nutr. 20 PubMed
  7. Yin OQ, Rudoltz M, Galetic I, Filian J, Krishna A, Zhou W, Custodio J, Golor G, Schran H. Effects of yogurt and applesauce on the oral bioavailability of nilotinib in healthy volunteers. J Clin Pharmacol. 2011 Nov;51(11):1580-6. PubMed
  8. Küçükosmanoglu E, Özen E, Eltan SB, Özkars MY, Keskin Ö. Most children who are allergic to cow's milk tolerate yogurt. J Int Med Res. 2018;46(12):5099-5106. PubMed
  9. Zhang K, Dai H, Liang W, Zhang L, Deng Z. Fermented dairy foods intake and risk of cancer. Int J Cancer. 2019;144(9):2099-2108. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Yogurt and Levonorgestrel Together: Common Questions

Is it safe to take Yogurt with Levonorgestrel?
We do not list a known interaction between Yogurt and Levonorgestrel. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Yogurt and Levonorgestrel have any of the same side effects?
Yes — our sources link each of them separately to 4 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Yogurt and Levonorgestrel combination checked?
Interactions in our licensed database are recorded against drug classes. Levonorgestrel is filed under 6 classifications, and Yogurt has documented interactions with 3 drug classes — none of Levonorgestrel's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Yogurt interact with any other medications?
Yes. Yogurt has 22 documented drug interactions in our database — Levonorgestrel is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Levonorgestrel interact with any supplements?
Yes. Levonorgestrel has documented interactions with 191 supplements in our database — Yogurt is not one of them. The Levonorgestrel interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Levonorgestrel and Yogurt?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.