Borage Oil 1000 mg Ingredients & Drug Interactions
by DC
What is this page for?
First and foremost: checking Borage Oil 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Borage Oil 1000 mg is a dietary supplement by DC with 4 active ingredients. Its ingredients are commonly taken for heart health, healthy cooking fat, skin moisturizing.Based on those ingredients, 312 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Borage Oil, Oleic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Borage Oil 1000 mg by DC
Ask about any prescription or over-the-counter medication and we check it for interactions with Borage Oil 1000 mg by DC — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Borage Oil 1000 mg by DC
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains five active ingredients. Borage oil itself is the main component, delivering fatty acids including gamma-linolenic acid (GLA).
The product also lists Oleic Acid, Linoleic Acid, Gamma-Linolenic Acid, and Polyunsaturated Fat as distinct active ingredients — though some of these overlap with what's naturally in borage. The inactive ingredients are gelatin (the capsule), vegetable glycerin, and mixed tocopherols (a form of vitamin E used as a preservative).
Does it work?
Not established
For Oleic Acid (one of the fatty acids in this product), the evidence suggests it may be helpful for high cholesterol and coronary heart disease — both rated Possibly Effective. For borage oil itself, the data shows it's likely ineffective for eczema (atopic dermatitis), and we don't have enough reliable evidence yet to rate it for ADHD, acute respiratory distress syndrome, or alcoholism.
The evidence on borage for most conditions remains thin.
How safe is it?
Well-documented data
Borage seed oil is generally well tolerated in the short term, though some people experience belching, bloating, diarrhea, and soft stools. The safety picture gets murkier with pregnancy and longer use.
Borage plant parts — leaf, flower, and seed — can contain liver-toxic alkaloids called pyrrolizidine alkaloids (PAs), and the facts advise against use during pregnancy because of this risk and concern for the uterus. Although borage seed oil itself contains little to no PAs, products aren't always certified free of them, so the risk of contamination from other plant parts exists.
If you're pregnant, breastfeeding, or planning either, talk with your doctor or pharmacist before taking this.
Meds to double-check
Moderate interaction found
Check before taking if you're on blood thinners or antiplatelet drugs (like warfarin or clopidogrel) — borage may increase bleeding risk. Also confirm with your doctor or pharmacist if you take phenothiazine antipsychotics or CYP3A4-inducing medications.
No interactions are documented for the other active ingredients we checked.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Borage oil may have a role for cholesterol and heart health, but the evidence is preliminary. If you take blood thinners, antipsychotics, or drugs that induce liver enzymes, you'll need to clear this with your doctor or pharmacist first — the interaction risks are real.
Avoid it in pregnancy. Talk it over with your own healthcare provider before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Borage Oil 1000 mg, straight from the product label.
| Brand | DC |
|---|---|
| Net contents | 90 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2021 |
| DSLD ID | 244637 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Borage Oil 1000 mg by DC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Calories from Fat | 10 Calorie(s) | -- |
| Total Fat | 1 Gram(s) | 2% |
| Polyunsaturated Fat | 0.5 Gram(s) | -- |
| Gamma-Linolenic Acid | 190 mg | -- |
| Linoleic Acid | 320 mg | -- |
| Oleic Acid | 160 mg | -- |
| Approximate Fatty Acid Content | 0 NP | -- |
| Borage Oil | 1000 mg | -- |
Other ingredients: Gelatin, Vegetable Glycerin, Mixed Tocopherols
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 1 to 3 softgels daily.
Precautions
Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Keep out of reach of children.
Caution: If you are pregnant, nursing, epileptic or schizophrenic do not take this product.
Contains soy or soy derivatives.
Formulation
Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
Contains no preservatives, sugar, starch, milk, lactose, wheat, yeast, fish, artificial color, flavor, sweetener, Non-GMO.
Made in USA
Gluten free
Supports skin, nerve and joint health
Storage
Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).
Formula
Dee Cee Borage Oil softgels supply pure Borage Oil, the richest source of Gamma Linolenic Acid (GLA)
Rich source of GLA
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Quali Pure
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Borage Oil 1000 mg by DC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Borage Oil 1000 mg by DC
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Approximate Fatty Acid Content
- › Gamma-Linolenic Acid
- › Linoleic Acid
- › Oleic Acid
Borage Oil
Interacts with226 drugs
Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arth...
Borage Oil monograph & interactionsOther (inactive) ingredients: Gelatin, Vegetable Glycerin, Mixed Tocopherols. These complete the product’s ingredient list but are not active constituents.
Borage Oil 1000 mg by DC Drug Interactions
HelloPharmacist Interaction Report
Borage Oil 1000 mg by DC does interact with several medication types.
The most serious concern is with blood thinners and antiplatelet drugs (like warfarin, aspirin, and clopidogrel). Borage seed oil contains compounds that may thin the blood further and increase bleeding risk — the effect is rated Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
The product also carries Moderate-severity interactions with phenothiazine antipsychotics (such as chlorpromazine), where there's theoretical concern that borage oil might lower the seizure threshold. Additionally, borage may increase toxic metabolite levels of certain drugs that induce CYP3A4 liver enzymes, though this depends on whether your borage product contains liver-toxic alkaloids.
We were unable to check three other active ingredients in this product — Polyunsaturated Fat, Gamma-Linolenic Acid, and Linoleic Acid — so we hold no interaction data for them. Altogether, these interactions span 313 individual medications.
Please use the medication checker on this page to confirm whether any of your prescriptions fall into these categories before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Borage Oil 1000 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Borage Oil 1000 mg interact with 312 drugs. Click any drug to see the details.
2 of the 4 ingredients in Borage Oil 1000 mg interact with drugs. Each result below shows which ingredient is responsible. Borage Oil Oleic Acid
AbciximabReoPro
How Abciximab interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilPhenothiazines Moderate
Interaction Summary
Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Read the full Borage Oil + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil + Aminoglutethimide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilPhenothiazines Moderate
Interaction Summary
Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Read the full Borage Oil + Amitriptyline, Perphenazine interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Antithrombin Iii interactionApalutamideErleada
How Apalutamide interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil + Apalutamide interactionApixabanEliquis
How Apixaban interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Apixaban interactionAprepitantCinvanti, Emend
How Aprepitant interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil + Aprepitant interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil + Aprobarbital, Butabarbital, Phenobarbital interactionAprocitentanTryvio
How Aprocitentan interacts with Borage Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Borage OilCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil + Aprocitentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Borage Oil 1000 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Borage Oil
Anticoagulant/Antiplatelet Drugs
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In healthy individuals, borage seed oil supplementation does not seem to affect platelet aggregation. However, gamma-linolenic acid, a constituent of borage seed oil, seems to decrease platelet aggregation by 45% and increase the risk of bleeding by 40% in animal and clinical research.
Cytochrome P450 3A4 (Cyp3A4) Inducers
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Although borage seed oil contains little to no PAs, some borage plant parts, such as the leaf, flower, and seed, can contain hepatotoxic PAs. Hepatotoxic PAs are substrates of CYP3A4, which converts these chemicals into toxic metabolites. Tell patients to avoid borage preparations that are not certified and labeled as hepatotoxic PA-free.
Phenothiazines
Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Borage seed oil contains gamma-linolenic acid (GLA). There is concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines. This is based on limited data from two reports published in the 1980s. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with evening primrose, another source of GLA. However, none experienced an actual seizure. In the other report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily was added. One of these patients had a prior history of seizures. It is unclear whether evening primrose had any additive epileptogenic effects with the phenothiazines, but there is no evidence that taking GLA-containing supplements alone can cause seizures.
Oleic Acid
Antidiabetes Drugs
Theoretically, oleic acid might increase the effects of antidiabetes drugs. Preliminary clinical research in patients with type 2 diabetes taking oral hypoglycemic drugs shows that eating a diet rich in oleic acid from olive oil decreases fasting blood glucose levels when compared to eating a diet rich in linoleic acid from sunflower oil. It is unknown if taking oleic acid supplements would have this effect or if this change is clinically significant. Until more is known, use caution. Dose adjustment may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.
Brand information
Manufacturer and brand details for Borage Oil 1000 mg, from the product label.
DC
See all DC products- Name
- Dee Cee Laboratories, Inc.
- Street Address
- 304 Dee Cee Rd.
- City
- White House
- State
- TN
- ZipCode
- 37188
Borage Oil 1000 mg by DC: Common Questions
Does Borage Oil 1000 mg by DC interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is borage oil safe during pregnancy?
What are the most common side effects?
Does borage oil actually work for eczema?
Can I take this if I'm on a blood thinner like warfarin?
Is this certified free of liver-toxic alkaloids?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Borage Oil 1000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Borage Oil 1000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Oleic Acid
Interacts with 86 drugsOleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...
Read the full Oleic Acid monograph → Herb & supplement monographBorage
Interacts with 226 drugsBorage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arthritis with mixed results. The plant's le...
Read the full Borage monograph →Sources & How We Checked
Borage Oil 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Oleic Acid 19 references
- Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
- Gillingham, L. G., Gustafson, J. A., Han, S. Y., Jassal, D. S., and Jones, P. J. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr 2011;105(3):417-427. PubMed
- Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiova
- Cater, N. B., Heller, H. J., and Denke, M. A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am.J Clin.Nutr PubMed
- Mozaffarian D, Clarke R. Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils. Eur J Clin Nutr. 2009;63(Suppl 2):S22-33. PubMed
- Cao Y, Hou L, Wang W. Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies. Int J Cancer. 2016;138(8):1894-904. doi: 10.1002/ijc.29938. PubMed
- FDA completes review of qualified health claim petition for oleic acid and the risk of coronary heart disease. November 2018. Available at: www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm624758.htm. Accessed January 25, 2019.
- Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity. 2016;24(11):2261-2268. PubMed
- Bowen KJ, Kris-Etherton PM, West SG, et al. Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity. J Nutr. 2019;149(3 PubMed
- Steffen BT, Duprez D, Szklo M, Guan W, Tsai MY. Circulating oleic acid levels are related to greater risks of cardiovascular events and all-cause mortality: The Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol. 2018;12(6):1404-1412. PubMed
- Banim PJ, Luben R, Khaw KT, Hart AR. Dietary oleic acid is inversely associated with pancreatic cancer - Data from food diaries in a cohort study. Pancreatology. 2018;18(6):655-660. PubMed
- Morin SJ, Gaziano JM, Djoussé L. Relation between plasma phospholipid oleic acid and risk of heart failure. Eur J Nutr. 2018;57(8):2937-2942. PubMed
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