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Dietary supplement

Brain Octane Oil Ingredients & Drug Interactions

by Bulletproof

Brain Octane Oil label
See full label image
Liquid Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Brain Octane Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Brain Octane Oil is a dietary supplement by Bulletproof with 1 active ingredient. Its ingredients are commonly taken for candida and yeast overgrowth, gut health support, antimicrobial.Based on those ingredients, 262 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Caprylic Acid Triglycerides. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Brain Octane Oil by Bulletproof

Ask about any prescription or over-the-counter medication and we check it for interactions with Brain Octane Oil by Bulletproof — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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Computed from our clinical databases

HelloPharmacist Scorecard of Brain Octane Oil by Bulletproof

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Caprylic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 262 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Brain Octane Oil, straight from the product label.

Brand Bulletproof
Net contents 16 fl. Oz.; 1 PT; 473 mL
Market status Off market
Date entered into DSLD Dec 22, 2017
DSLD ID 81158
Product type Fat/fatty Acid
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Brain Octane Oil by Bulletproof, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tbsp
Maximum serving Sizes:
1 Tbsp
Servings per container
32
IngredientAmount% DV
Calories130 Calorie(s)--
Saturated Fat14 Gram(s)70%
Trans Fat0 Gram(s)--
Total Fat14 Gram(s)22%
Caprylic Acid Triglycerides14 Gram(s)--

Other ingredients: Caprylic Acid Triglycerides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Do more. Crave less. This is your fuel to power brain and body.

The Science Brain Octane Oil keeps your brain on full blast and your belly slim. It's a brain-boosting fat, extracted from the most potent part of the coconut, that is converted into brain-fueling, fat-burning ketone energy more efficiently than MCT or coconut oils that contain lauric acid. What's that mean for you? More brain power and lasting energy with fewer cravings. Love it or your money back.

Fat for fuel

Amplified energy & mental performance

All edible oils, including Brain Octane, react with certain plastics, including Styrofoam, and should only be used with utensils and containers made of metal, glass, ceramic, or safe HDPE plastics.

This product is packaged in a non-BPA, recyclable HDPE bottle to reduce the environmental impacts of padding, packaging and shipping glass bottles.

Brand IP Statement(s)

Brain Octane Oil gives your body what it needs - an efficient high-energy fuel.

2016 Bulletproof 360, Inc. All rights reserved.

A key ingredient in the Bulletproof Coffee recipe

Suggested/Recommended/Usage/Directions

It is totally flavorless and totally satisfying - great on salads, mixed into smoothies, and a key ingredient in the Bulletproof Coffee recipe.

Directions Try one teaspoon at a time first and then build up over several days to a full 1-tablespoon serving, as often as you'd like. Just start small - too much too soon can upset your stomach. For low temperature cooking only. Do not heat above 320(0)F.

Precautions

Do not heat above 320(0)F.

Safety-sealed for your protection. Return for replacement if the outer seal is broken.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Zero lauric acid

No palm oil.

FDA Statement of Identity

Dietary Supplement

Storage

Very stable. No refrigeration required.

Formula

Extracted from 100% orangutan-friendly coconut oil.

General

R01 161202

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Brain Octane Oil by Bulletproof label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Brain Octane Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Brain Octane Oil by Bulletproof

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tbsp Dosage formLiquid Servings per container32 Amounts shown are per serving.

Caprylic Acid Triglycerides

Interacts with
262 drugs
14 Gram(s) per serving

Caprylic acid is a medium-chain fatty acid found in coconut oil and palm kernel oil that is popularly used for yeast overgrowth and gut health. While...

Caprylic Acid Triglycerides monograph & interactions

Other (inactive) ingredients: Caprylic Acid Triglycerides. These complete the product’s ingredient list but are not active constituents.

Interaction report

Brain Octane Oil by Bulletproof Drug Interactions

Brain Octane Oil contains a single active ingredient, and it has known interactions with 262 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Brain Octane Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
262Drugs
262 Moderate

Ingredients driving the most interactions

Caprylic Acid Triglycerides 262

Individual Drug Interactions

The ingredients in Brain Octane Oil interact with 262 drugs. Click any drug to see the details.

1 of the 1 ingredient in Brain Octane Oil interact with drugs. Each result below shows which ingredient is responsible. Caprylic Acid Triglycerides

Each ingredient & the kinds of drugs it affects

For each ingredient in Brain Octane Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Caprylic Acid Triglycerides3 drug types · 262 drugs

Antihypertensive Drugs

Theoretically, caprylic acid might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that caprylic acid might have positive inotropic effects, resulting in reduced arterial pressure and vascular resistance and increased cardiac output.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

Theoretically, caprylic acid might increase plasma concentrations of NSAIDs.
In vitro research suggests that caprylic acid might displace NSAIDs from binding sites on albumin. This effect has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, caprylic acid might increase plasma concentrations of warfarin.
In vitro research suggests that high doses of caprylic acid might displace warfarin from albumin binding sites. This effect has not been reported in humans.

Likelihood Possible Evidence D
Caprylic Acid Triglycerides full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Brain Octane Oil, from the product label.

Bulletproof

See all Bulletproof products
Name
Bulletproof 360, INC.
City
Bellevue
State
WA
ZipCode
98004
Phone Number
1-844-273-9321
Web Address
bulletproof.com
Pharmacist Counseling Corner

Brain Octane Oil by Bulletproof: Common Questions

Does Brain Octane Oil by Bulletproof interact with any medications?
Yes. Based on its ingredients, Brain Octane Oil has a known interaction with 262 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Brain Octane Oil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Brain Octane Oil is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Brain Octane Oil label
Go deeper

The Full Monographs Behind Brain Octane Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Caprylic Acid

Interacts with 262 drugs

Caprylic acid is a medium-chain fatty acid found in coconut oil and palm kernel oil that is popularly used for yeast overgrowth and gut health. While laboratory studies show it has antimicro...

Read the full Caprylic Acid monograph →
Sources

Sources & How We Checked

Brain Octane Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Caprylic Acid 5 references
  1. Massolini G, Aubry AF, McGann A, Wainer IW. Determination of the magnitude and enantioselectivity of ligand binding to rat and rabbit serum albumins using immobilized-protein high performance liquid chromatography stationary phases. Biochem Pharmacol 1993 PubMed
  2. Kristev A, Mitkov D, Lukanov Y, Chapkynov P. The effect of octanoic fatty acid on the cardiovascular system of the guinea pig. Cor Vasa 1989;31(4):321-7.
  3. Hayball PF, Holman JW, Nation RL. Influence of octanoic acid on the reversible protein binding of ketorolac enantiomers to human serum albumin (HSA): comparative liquid chromatographic studies using a HSA chiral stationary phase. J Chromatogr B Biomed App PubMed
  4. Noctor TA, Wainer IW, Hage DS. Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase. J Chromatogr 1992;5 PubMed
  5. Voller B, Lines E, McCrossin G, et al. Dose-escalation study of octanoic acid in patients with essential tremor. J Clin Invest. 2016;126(4):1451-7. PubMed

See these in context on the Caprylic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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