CBD 1200 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking CBD 1200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CBD 1200 mg is a dietary supplement by Medical Mike's with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Full Spectrum Hemp Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CBD 1200 mg by Medical Mike's
Ask about any prescription or over-the-counter medication and we check it for interactions with CBD 1200 mg by Medical Mike's — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CBD 1200 mg by Medical Mike's
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Medical Mike's CBD 1200 mg contains 1 active ingredient: full spectrum hemp extract, which includes cannabinoids and other compounds found naturally in hemp. The liquid also contains medium chain triglyceride oil as an inactive ingredient to carry the extract.
Does it work?
Couldn't assess
The evidence we hold doesn't establish whether this product works for constipation, eczema, or familial hypercholesterolemia — the ratings for each are insufficient reliable evidence. If you're thinking about it for one of these issues, talk it over with your doctor or pharmacist about what the current research actually supports.
How safe is it?
Well-documented data
Hemp seed foods and oils are generally well tolerated in normal amounts, but concentrated extracts like this one are less well studied. The safety data we have advises caution with supplements and extracts rather than whole food amounts.
Serious side effects are rare but have been reported: anaphylaxis and allergic reactions (hives, facial swelling, breathing trouble) can occur, especially on first exposure, and there's a case report of liver inflammation in a young child given high-dose hemp extract. Most people tolerate it without problems, but if you're allergic to hemp seed or have a history of severe allergies, be especially careful.
Meds to double-check
Moderate interaction found
Before you take Medical Mike's CBD 1200 mg, double-check with your own doctor or pharmacist if you're on estrogen-containing therapies, blood thinners or antiplatelet drugs, blood pressure medications, ACE inhibitors, or any drug metabolized by CYP1A2 or CYP3A4 enzymes. The estrogen interaction is the most serious concern.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is mainly a consideration if you want to try hemp extract for one of the conditions mentioned, though the evidence doesn't yet show it works. If you take estrogen therapy, blood thinners, blood pressure medications, or drugs broken down by your liver, check with your doctor or pharmacist before adding it — the interactions could change how your medications perform.
Altogether, these interactions span 939 individual medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CBD 1200 mg, straight from the product label.
| Brand | Medical Mike's |
|---|---|
| Net contents | 30 Milliliter(s); 1 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2024 |
| DSLD ID | 309197 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CBD 1200 mg by Medical Mike's, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Fat | 0.5 Gram(s) | 1% |
| Calories | 4 Calorie(s) | -- |
| Calories from Fat | 4 Calorie(s) | -- |
| Full Spectrum Hemp Extract | 20 mg | -- |
Other ingredients: Medium Chain Triglyceride Oil
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before using.
FDA Disclaimer Statement
This product has not been analyzed by the FDA. There is limited information on the effects of using this product.
Precautions
If you have a medical condition or take pharmaceutical drugs, please consult your physician before use. Not to be used during pregnancy or lactation.
Keep out of reach of children.
General Statements
Scan the QR code for lab results
@medicalmikes
Formulation
Certified Organic by NOFA-NY, LLC USDA Organic
Seals/Symbols
USDA Organic Grown in N.Y.
Formula
Premium full spectrum CBD 1200 mg
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CBD 1200 mg by Medical Mike's label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CBD 1200 mg by Medical Mike's
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.5 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Full Spectrum Hemp Extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Full Spectrum Hemp Extract monograph & interactionsOther (inactive) ingredients: Medium Chain Triglyceride Oil. These complete the product’s ingredient list but are not active constituents.
CBD 1200 mg by Medical Mike's Drug Interactions
HelloPharmacist Interaction Report
Medical Mike's CBD 1200 mg is a full spectrum hemp extract liquid, and it does interact with several medication types.
The most serious concern is with estrogen therapies (the hormones used in birth control and hormone replacement). Hemp may interfere with how your body processes estrogen, potentially reducing its effect — though the exact mechanism isn't fully understood.
Read the full breakdown — every affected drug type, severity by severity
Hemp can also interact with blood thinners and antiplatelet drugs (medications that reduce clotting), raising your bleeding risk, though human evidence of this effect is limited. It may have additive effects with blood pressure medications and ACE inhibitors (drugs that lower blood pressure), which could cause your pressure to drop too far.
Additionally, hemp may speed up how your liver breaks down certain drugs processed through the CYP1A2 and CYP3A4 pathways, potentially making them less effective — this affects a broad range of medications.
Additionally, we could not check a few inactive ingredients in the formulation. Run your exact medications through the search tool on this page to see whether any of them fall into these categories before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CBD 1200 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CBD 1200 mg interact with 938 drugs. Click any drug to see the details.
1 of the 1 ingredient in CBD 1200 mg interact with drugs. Each result below shows which ingredient is responsible. Full Spectrum Hemp Extract
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Conjugated Estrogens, Methyltestosterone interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Cyproterone Acetate, Ethinyl Estradiol interactionDesogestrel, Ethinyl EstradiolDesogen, Marvelon, Marvelon 21, Marvelon 28, Mircette, Ortho-Cept +2 more
How Desogestrel, Ethinyl Estradiol interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Desogestrel, Ethinyl Estradiol interactionDrospirenone, EstetrolNextstellis
How Drospirenone, Estetrol interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Drospirenone, Estetrol interactionDrospirenone, Ethinyl EstradiolAngeliq, Gianvi, Yasmin
How Drospirenone, Ethinyl Estradiol interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Drospirenone, Ethinyl Estradiol interactionEsterified EstrogensEstratab, Menest
How Esterified Estrogens interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Esterified Estrogens interactionEsterified Estrogens, MethyltestosteroneEstratest
How Esterified Estrogens, Methyltestosterone interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Esterified Estrogens, Methyltestosterone interactionEstradiolDivigel, Elestrin, Estrace, Estraderm, Estring, Evamist +6 more
How Estradiol interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Estradiol interactionEstradiol, MedroxyprogesteroneDivitren
How Estradiol, Medroxyprogesterone interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Estradiol, Medroxyprogesterone interactionEstradiol, Norethindrone AcetateActivella
How Estradiol, Norethindrone Acetate interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Estradiol, Norethindrone Acetate interactionEstradiol, NorgestimateOrtho-Prefest
How Estradiol, Norgestimate interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Estradiol, Norgestimate interactionEstradiol, ProgesteroneBijuvanda
How Estradiol, Progesterone interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Estradiol, Progesterone interactionEstrogenEstrogen
How Estrogen interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Estrogen interactionEstroneOrtho-Est
How Estrone interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Estrone interactionEstropipateOgen, Ortho EST
How Estropipate interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Estropipate interactionEthiny Estradiol, LevonorgestrelLogynon, Microgynon 30 ED
How Ethiny Estradiol, Levonorgestrel interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Ethiny Estradiol, Levonorgestrel interactionEthinyl EstradiolEstinyl
How Ethinyl Estradiol interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Ethinyl Estradiol interactionEthinyl Estradiol, DesogestrelApri, Cesia, Cyclessa, Gedarel, Kariva, Linessa +4 more
How Ethinyl Estradiol, Desogestrel interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Ethinyl Estradiol, Desogestrel interactionEthinyl Estradiol, DrospirenoneYaz
How Ethinyl Estradiol, Drospirenone interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Ethinyl Estradiol, Drospirenone interactionEthinyl Estradiol, Ethynodiol DiacetateDemulen 1/35, Demulen 1/50, Demulen Compack, Kelnor 1/35, Zovia, Zovia 1/35 +1 more
How Ethinyl Estradiol, Ethynodiol Diacetate interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Ethinyl Estradiol, Ethynodiol Diacetate interactionEthinyl Estradiol, LevonorgestrelAlesse, Alesse 21, Alesse 28, Aviane, Enpresse, Jolessa +18 more
How Ethinyl Estradiol, Levonorgestrel interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Ethinyl Estradiol, Levonorgestrel interactionEthinyl Estradiol, NorethindroneAranelle, Brevicon, Brevicon .5/35 21 day, Brevicon .5/35 28 day, Brevicon 1/35 21 day, Brevicon 1/35 28 day +50 more
How Ethinyl Estradiol, Norethindrone interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Ethinyl Estradiol, Norethindrone interactionEthinyl Estradiol, Norethindrone, Ferrous FumarateEstrostep Fe, Femcon FE, Junel Fe 1.5/30, Loestrin Fe, Loestrin Fe 1.5/30, Loestrin Fe 1/20 +3 more
How Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interactionEthinyl Estradiol, NorgestimateCilest, Mononessa, Ortho Tri-Cyclen 28, Ortho Tri-Cyclen Lo, Ortho Tri-Cylcen, Ortho-Cyclen +5 more
How Ethinyl Estradiol, Norgestimate interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Ethinyl Estradiol, Norgestimate interactionEthinyl Estradiol, NorgestrelCryselle, Lo/Ovral, Low-Ogestrel, Ogestrel 0.5/50, Ovral
How Ethinyl Estradiol, Norgestrel interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Ethinyl Estradiol, Norgestrel interactionEthinyl Estradiol, LevonogestrelLybrel
How Ethinyl Estradiol, Levonogestrel interacts with CBD 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Ethinyl Estradiol, Levonogestrel interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CBD 1200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Full Spectrum Hemp Extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for CBD 1200 mg, from the product label.
Medical Mike's
See all Medical Mike's products- Name
- Medical Mike's
- City
- Tarrytown
- State
- NY
- ZipCode
- 10591
- Web Address
- Medicalmikes.com
CBD 1200 mg by Medical Mike's: Common Questions
Does CBD 1200 mg by Medical Mike's interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while pregnant or breastfeeding?
What's full spectrum hemp extract?
Can I have an allergic reaction to this?
Is this safe in high doses?
Will this affect my birth control?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CBD 1200 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CBD 1200 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
CBD 1200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC