Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Hemp Reserve CBN 600 mg Ingredients & Drug Interactions

by Medical Mike's

Hemp Reserve CBN 600 mg label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hemp Reserve CBN 600 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hemp Reserve CBN 600 mg is a dietary supplement by Medical Mike's with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Full Spectrum Hemp Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Hemp Reserve CBN 600 mg by Medical Mike's

Ask about any prescription or over-the-counter medication and we check it for interactions with Hemp Reserve CBN 600 mg by Medical Mike's — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Hemp Reserve CBN 600 mg by Medical Mike's

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Hemp Reserve CBN 600 mg contains two active ingredients: cannabinol and full spectrum hemp extract. The product comes as a liquid, and its 2 active ingredients work together in the formula.

The inactive ingredients (coconut oil and additional cannabinol extract) serve as carriers and excipients to deliver the actives.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hemp product and its label doesn't state a use — see Hemp's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we have on file doesn't establish that full spectrum hemp is effective for the conditions studied — constipation, eczema (atopic dermatitis), and high cholesterol (familial hypercholesterolemia) all carry a rating of insufficient reliable evidence to rate. That means the data we hold isn't strong enough yet to say whether it works for these uses or not.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods in normal dietary amounts are generally well tolerated. However, concentrated extracts and supplements like this one are less studied, so caution is advised.

In larger amounts, hemp seed oil appears to be well tolerated overall. Rare serious side effects have been reported: anaphylaxis (severe allergic reaction), heart rhythm problems (long QT syndrome and torsades de pointes), and fainting.

Allergic reactions to hemp seed do occur, though uncommon — symptoms can include hives, facial swelling, breathing trouble, and worsening asthma. There's also a case report of elevated liver enzymes and hepatitis in a young child given a high-dose hemp extract.

No pregnancy or lactation safety data is on file for this product — talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check if you're on estrogen or hormone therapy (moderate interaction risk). Also check if you take blood pressure medications — whether ACE inhibitors, other antihypertensive drugs, or any drug that your liver breaks down using the CYP1A2 or CYP3A4 pathways.

Blood thinner or antiplatelet medications warrant a quick review too.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're on estrogen therapy, blood pressure medications, blood thinners, or drugs that depend on your liver's CYP1A2 or CYP3A4 enzymes, check your medications with the tool on this page before you start. Hemp is generally well tolerated in food amounts, but concentrated extracts are less studied.

If you have a known seed allergy, be cautious. Talk to your pharmacist or doctor about whether this product fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hemp Reserve CBN 600 mg, straight from the product label.

Brand Medical Mike's
Net contents 30 mL; 1 Ounce(s)
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 308294
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hemp Reserve CBN 600 mg by Medical Mike's, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
30
IngredientAmount% DV
Calories8 Calorie(s)--
Calories from Fat8 Calorie(s)--
Total Fat1 Gram(s)2%
Cannabinol10 mg--
Full Spectrum Hemp Extract10 mg--

Other ingredients: Coconut Oil, Fractionated, Cannabinol Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before using.

FDA Disclaimer Statement

This product has not been analyzed by the FDA.

Precautions

There is limited information on the effects of using this product.

If you have a medical condition or take pharmaceutical drugs, please consult your physician before use. Not to used during pregnancy or lactation.

Keep out of reach of children.

Seals/Symbols

Grown in N.Y.

Formula

1:1 ratio formula CBN:CBD

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hemp Reserve CBN 600 mg by Medical Mike's label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hemp Reserve CBN 600 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hemp Reserve CBN 600 mg by Medical Mike's

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Cannabinol

10 mg per serving

Full Spectrum Hemp Extract

Interacts with
938 drugs
10 mg per serving

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Full Spectrum Hemp Extract monograph & interactions

Other (inactive) ingredients: Coconut Oil, Fractionated, Cannabinol Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hemp Reserve CBN 600 mg by Medical Mike's Drug Interactions

Want to check YOUR meds against Hemp Reserve CBN 600 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

Full Spectrum Hemp Extract 938

Individual Drug Interactions

The ingredients in Hemp Reserve CBN 600 mg interact with 938 drugs. Click any drug to see the details.

1 of the 2 ingredients in Hemp Reserve CBN 600 mg interact with drugs. Each result below shows which ingredient is responsible. Full Spectrum Hemp Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Hemp Reserve CBN 600 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Full Spectrum Hemp Extract6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Full Spectrum Hemp Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hemp Reserve CBN 600 mg, from the product label.

Medical Mike's

See all Medical Mike's products
Name
Medical Mike's
City
Tarrytown
State
NY
ZipCode
10591
Web Address
Medicalmikes.com
Pharmacist Counseling Corner

Hemp Reserve CBN 600 mg by Medical Mike's: Common Questions

Does Hemp Reserve CBN 600 mg by Medical Mike's interact with any medications?
Yes. Based on its ingredients, Hemp Reserve CBN 600 mg has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hemp Reserve CBN 600 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on birth control or hormone replacement therapy?
Not without checking first. Hemp may theoretically interfere with how your body handles estrogens, possibly by changing estradiol levels. Talk to your pharmacist or doctor before you start — they can review your specific medication and help you decide.
What is cannabinol (CBN), and why is it in this product?
Cannabinol is one of the two active ingredients in this formula. We don't have interaction data on file for it, so we can't tell you what its specific role is or how it works — only that it's present in the product alongside full spectrum hemp extract.
Is hemp safe if I have a seed allergy?
Allergic reactions to hemp seed do occur, though they're uncommon. Symptoms can range from hives and facial swelling to breathing trouble and worsening asthma. If you have a known seed allergy, be cautious and talk to your pharmacist before trying this.
Does this product actually work for what it's marketed for?
The evidence we have on file doesn't establish that hemp is effective for constipation, eczema, or high cholesterol — all carry a rating of insufficient reliable evidence. That means we don't have enough data yet to say whether it works for these uses.
Is it safe to take if I'm pregnant or breastfeeding?
We don't have safety data on file for pregnancy or breastfeeding with this product. Talk with your doctor or pharmacist — they can give you personalized advice based on your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hemp Reserve CBN 600 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hemp Reserve CBN 600 mg label
Go deeper

The Full Monographs Behind Hemp Reserve CBN 600 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hemp

Interacts with 938 drugs

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...

Read the full Hemp monograph →
Sources

Sources & How We Checked

Hemp Reserve CBN 600 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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