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Dietary supplement

CBD Broad Spectrum Softgels 25 mg Ingredients & Drug Interactions

by Jane Health

Softgel Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

CBD Broad Spectrum Softgels 25 mg is a dietary supplement by Jane Health with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Broad Spectrum Hemp Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of CBD Broad Spectrum Softgels 25 mg by Jane Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: broad spectrum hemp extract at 25 mg per softgel. Broad spectrum means it includes multiple compounds from the hemp plant.

The softgel itself is made up of inactive ingredients — coconut oil, gelatin, glycerin, and purified water — that help deliver the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hemp product and its label doesn't state a use — see Hemp's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for broad spectrum hemp extract isn't established in the data we hold. The effectiveness ratings we have cover constipation, eczema, and familial high cholesterol (a genetic cholesterol condition), but all are rated as having insufficient reliable evidence to rate.

If you're considering this product for a specific health concern, talk with your pharmacist about what the current research actually supports.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods are generally well tolerated in normal amounts, but concentrated extracts like this supplement are less well studied. Orally, hemp products are generally tolerated overall.

Rare serious side effects including anaphylaxis, long QT syndrome (a heart rhythm problem), and syncope (fainting) have been reported rarely. Allergic reactions to hemp seed do occur, though uncommon — symptoms can range from hives and facial swelling to breathing problems.

There's also a rare case report of elevated liver enzymes and hepatitis in a young child given very high doses of hemp extract for seizures, though this involved amounts much larger than this product.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product against estrogen or hormone therapy (moderate interaction concern). Also screen it against blood pressure medications, ACE inhibitors, blood thinners, and any medications your liver breaks down via the CYP1A2 or CYP3A4 pathways — all are minor interaction concerns.

Use the medication checker below to verify your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take estrogen therapy, blood pressure medications, blood thinners, or drugs metabolized through your liver's CYP1A2 or CYP3A4 pathways, check with your pharmacist before using this product. Even if you don't take those medications, hemp extract is less studied as a concentrated supplement than as a food, so caution is warranted.

Talk to your pharmacist about whether this product is right for you and your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CBD Broad Spectrum Softgels 25 mg, straight from the product label.

Brand Jane Health
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 320462
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CBD Broad Spectrum Softgels 25 mg by Jane Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
IngredientAmount% DV
Broad Spectrum Hemp Extract25 mg--

Other ingredients: Coconut Oil, Fractionated, Gelatin, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one (1) to two (2) softgels daily.

Precautions

Do not use if safety seal is damaged or missing.

Not intended for use by individuals under the age of 18 without adult supervision.

Do not use if you are pregnant or nursing. Consult a physician prior to use if you are taking any medications.

If any adverse reactions occur, discontinue use and consult your doctor. This product contains a total delta-9-THC concentration that does not exceed 0.3% on a dry-weight basis.

Keep out of children's reach.

Contains 750mg CBD per bottle.

Formulation

Made with love in the USA

Non-Detectable THC

Support and protection using the gifts from Mother Nature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

25 mg CBD per softgels

Seals/Symbols

Formulated in the USA GMP Good Manufacturing Practice Non-Detectable THC

Storage

Store in a cool, dry place.

See for yourself

CBD Broad Spectrum Softgels 25 mg by Jane Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in CBD Broad Spectrum Softgels 25 mg by Jane Health

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Broad Spectrum Hemp Extract

Interacts with
938 drugs
25 mg per serving Form: Cannabidiol

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Broad Spectrum Hemp Extract monograph & interactions

Other (inactive) ingredients: Coconut Oil, Fractionated, Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

CBD Broad Spectrum Softgels 25 mg by Jane Health Drug Interactions

Want to check YOUR meds against CBD Broad Spectrum Softgels 25 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in CBD Broad Spectrum Softgels 25 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Broad Spectrum Hemp Extract6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for CBD Broad Spectrum Softgels 25 mg, from the product label.

Jane Health

See all Jane Health products
Name
Barlow Herbal Specialties, LLC
Street Address
110 West 13775 South #9
City
Draper
State
Utah
ZipCode
84020
Phone Number
866-688-6757
Web Address
BarlowHerbal.com
Pharmacist Counseling Corner

CBD Broad Spectrum Softgels 25 mg by Jane Health: Common Questions

Does CBD Broad Spectrum Softgels 25 mg by Jane Health interact with any medications?
Yes. Based on its ingredients, CBD Broad Spectrum Softgels 25 mg has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CBD Broad Spectrum Softgels 25 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is broad spectrum hemp extract the same as CBD?
Not quite. Broad spectrum hemp extract contains multiple compounds from the hemp plant, whereas CBD isolate contains only cannabidiol. This product's extract includes a range of cannabinoids and other plant compounds, but the facts don't specify exactly which ones.
Can I take this if I'm pregnant or breastfeeding?
We don't have safety data on file for hemp extract during pregnancy or breastfeeding. Because this is a concentrated supplement rather than a food amount, it's especially important to talk with your doctor or pharmacist before using it — they can weigh the pros and cons for your situation.
What side effects might I experience?
Most people tolerate hemp products well. Rarely, allergic reactions occur — ranging from hives to facial swelling and breathing trouble. Very rare serious effects like anaphylaxis and heart rhythm problems have been reported. If you develop any signs of an allergy or unusual symptoms, stop and contact your doctor.
Does this product contain THC?
The facts don't specify whether this broad spectrum extract contains THC or how much. Because THC content can vary by product and batch, reach out to Jane Health directly or check the product label for third-party testing results.
Will this lower my blood pressure?
The evidence we hold doesn't establish that broad spectrum hemp extract works for blood pressure. However, because it may theoretically work alongside blood pressure medications, it's especially important to check with your pharmacist if you take those drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if CBD Broad Spectrum Softgels 25 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CBD Broad Spectrum Softgels 25 mg label
Go deeper

The Full Monographs Behind CBD Broad Spectrum Softgels 25 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

CBD Broad Spectrum Softgels 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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