CBD Drops Peppermint 500 mg Ingredients & Drug Interactions
by Jane Health
What is this page for?
First and foremost: checking CBD Drops Peppermint 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CBD Drops Peppermint 500 mg is a dietary supplement by Jane Health with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Broad Spectrum Hemp extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CBD Drops Peppermint 500 mg by Jane Health
Ask about any prescription or over-the-counter medication and we check it for interactions with CBD Drops Peppermint 500 mg by Jane Health — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CBD Drops Peppermint 500 mg by Jane Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: broad spectrum hemp extract, delivering 500 mg per bottle. Broad spectrum hemp extract includes multiple plant compounds from the hemp plant but is processed to remove most THC (the compound that gets you high).
The inactive ingredients are fractionated coconut oil and natural flavors — the coconut oil is the carrier that holds the hemp extract in liquid form.
Does it work?
Couldn't assess
The evidence we hold doesn't establish that hemp extract works for the conditions in our database — constipation, eczema, and familial hypercholesterolemia (a genetic cholesterol disorder) all show insufficient reliable evidence to rate. That doesn't mean it won't help with something else you have in mind, but we don't have effectiveness data on file for those uses.
How safe is it?
Well-documented data
Hemp seed foods are generally well tolerated in everyday amounts, but concentrated extracts and supplements like this one are less studied, so we'd recommend caution. In larger amounts, hemp seed oil appears well tolerated, though rare serious reactions have been reported — anaphylaxis (severe allergic reaction), long QT syndrome (a heart rhythm problem), and in one case of very high-dose extract in a young child, elevated liver enzymes and hepatitis.
Allergy to hemp seed is uncommon but documented; symptoms include hives, facial swelling, and breathing trouble. Safety data in pregnancy and lactation isn't on file for this ingredient, so if you're pregnant or nursing, talk with your doctor or pharmacist before using it.
Meds to double-check
Moderate interaction found
Double-check this product against estrogen therapy (birth control, hormone replacement) first — that's a Moderate interaction. Also check blood pressure medications, ACE inhibitors, blood thinners, and any drugs your liver processes through CYP1A2 or CYP3A4 enzymes — those are Minor but real.
Altogether, these interactions span 927 individual medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you're on hormone therapy, blood pressure medication, blood thinners, or drugs your liver metabolizes quickly, check your exact medications with the tool on this page before starting. Hemp extract is generally well tolerated in food amounts, but concentrated supplements carry more uncertainty.
A quick conversation with us can help you decide whether this product fits your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CBD Drops Peppermint 500 mg, straight from the product label.
| Brand | Jane Health |
|---|---|
| Net contents | 1 Fluid Ounce(s); 30 Milliliter(s) |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2025 |
| DSLD ID | 320463 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CBD Drops Peppermint 500 mg by Jane Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Broad Spectrum Hemp extract | 16.67 mg | -- |
Other ingredients: Coconut Oil, Fractionated, Natural Flavors
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Shake well. Take 1 mL (approx. 30 drops) per day.
Precautions
Not intended for use by anyone under the age of 18 without adult supervision.
Do not use if you are pregnant or nursing. Consult a physician prior to use if you are taking any medications.
If any adverse reactions occur, discontinue use and consult your doctor.
Keep out of children's reach.
This product contains a total delta-9-THC concentration that does not exceed 0.3% on a dry-weight basis.
Storage
Store in a cool, dry place.
Formulation
Made with love in the USA
Non-Detectable THC
Support and protection using the gifts from Mother Nature.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
500MG CBD per bottle
Seals/Symbols
Formulated in the USA GMP Good Manufacturing Practice Non-Detectable THC
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CBD Drops Peppermint 500 mg by Jane Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CBD Drops Peppermint 500 mg by Jane Health
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Broad Spectrum Hemp extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Broad Spectrum Hemp extract monograph & interactionsOther (inactive) ingredients: Coconut Oil, Fractionated, Natural Flavors. These complete the product’s ingredient list but are not active constituents.
CBD Drops Peppermint 500 mg by Jane Health Drug Interactions
HelloPharmacist Interaction Report
Jane Health's CBD Drops Peppermint 500 mg contains broad spectrum hemp extract, which has documented interactions with several medication types.
The most serious is with hormone therapy (estrogens) — a Moderate interaction. Animal research shows hemp may normalize estrogen levels in the bloodstream, which could theoretically interfere with how hormone replacement or birth control works.
The mechanism isn't fully understood, so if you're on estrogen therapy, you'll want to check this with us before starting.
Read the full breakdown — every affected drug type, severity by severity
Hemp also interacts with blood pressure medications (antihypertensive drugs and ACE inhibitors) at a Minor level. The concern is that hemp seed protein may lower blood pressure through enzyme inhibition, which could add to what your medication is already doing and make your pressure drop too much.
Animal studies support this, but human data is limited. Additionally, Minor interactions are documented with blood thinners (anticoagulant/antiplatelet drugs) — in theory hemp seed might increase bleeding risk, though a small human study found no effect on platelet function.
Hemp also appears to speed up how your liver processes certain medications, a Minor interaction affecting drugs metabolized through CYP1A2 and CYP3A4 enzymes.
Additionally, we don't hold interaction data for the peppermint flavoring or coconut oil in this product. Before you start these drops, please use the medication checker below to look up your exact prescriptions against this ingredient.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CBD Drops Peppermint 500 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CBD Drops Peppermint 500 mg interact with 938 drugs. Click any drug to see the details.
1 of the 1 ingredient in CBD Drops Peppermint 500 mg interact with drugs. Each result below shows which ingredient is responsible. Broad Spectrum Hemp extract
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Conjugated Estrogens, Methyltestosterone interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Cyproterone Acetate, Ethinyl Estradiol interactionDesogestrel, Ethinyl EstradiolDesogen, Marvelon, Marvelon 21, Marvelon 28, Mircette, Ortho-Cept +2 more
How Desogestrel, Ethinyl Estradiol interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Desogestrel, Ethinyl Estradiol interactionDrospirenone, EstetrolNextstellis
How Drospirenone, Estetrol interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Drospirenone, Estetrol interactionDrospirenone, Ethinyl EstradiolAngeliq, Gianvi, Yasmin
How Drospirenone, Ethinyl Estradiol interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Drospirenone, Ethinyl Estradiol interactionEsterified EstrogensEstratab, Menest
How Esterified Estrogens interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Esterified Estrogens interactionEsterified Estrogens, MethyltestosteroneEstratest
How Esterified Estrogens, Methyltestosterone interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Esterified Estrogens, Methyltestosterone interactionEstradiolDivigel, Elestrin, Estrace, Estraderm, Estring, Evamist +6 more
How Estradiol interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Estradiol interactionEstradiol, MedroxyprogesteroneDivitren
How Estradiol, Medroxyprogesterone interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Estradiol, Medroxyprogesterone interactionEstradiol, Norethindrone AcetateActivella
How Estradiol, Norethindrone Acetate interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Estradiol, Norethindrone Acetate interactionEstradiol, NorgestimateOrtho-Prefest
How Estradiol, Norgestimate interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Estradiol, Norgestimate interactionEstradiol, ProgesteroneBijuvanda
How Estradiol, Progesterone interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Estradiol, Progesterone interactionEstrogenEstrogen
How Estrogen interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Estrogen interactionEstroneOrtho-Est
How Estrone interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Estrone interactionEstropipateOgen, Ortho EST
How Estropipate interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Estropipate interactionEthiny Estradiol, LevonorgestrelLogynon, Microgynon 30 ED
How Ethiny Estradiol, Levonorgestrel interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Ethiny Estradiol, Levonorgestrel interactionEthinyl EstradiolEstinyl
How Ethinyl Estradiol interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol interactionEthinyl Estradiol, DesogestrelApri, Cesia, Cyclessa, Gedarel, Kariva, Linessa +4 more
How Ethinyl Estradiol, Desogestrel interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Desogestrel interactionEthinyl Estradiol, DrospirenoneYaz
How Ethinyl Estradiol, Drospirenone interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Drospirenone interactionEthinyl Estradiol, Ethynodiol DiacetateDemulen 1/35, Demulen 1/50, Demulen Compack, Kelnor 1/35, Zovia, Zovia 1/35 +1 more
How Ethinyl Estradiol, Ethynodiol Diacetate interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Ethynodiol Diacetate interactionEthinyl Estradiol, LevonorgestrelAlesse, Alesse 21, Alesse 28, Aviane, Enpresse, Jolessa +18 more
How Ethinyl Estradiol, Levonorgestrel interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Levonorgestrel interactionEthinyl Estradiol, NorethindroneAranelle, Brevicon, Brevicon .5/35 21 day, Brevicon .5/35 28 day, Brevicon 1/35 21 day, Brevicon 1/35 28 day +50 more
How Ethinyl Estradiol, Norethindrone interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Norethindrone interactionEthinyl Estradiol, Norethindrone, Ferrous FumarateEstrostep Fe, Femcon FE, Junel Fe 1.5/30, Loestrin Fe, Loestrin Fe 1.5/30, Loestrin Fe 1/20 +3 more
How Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interactionEthinyl Estradiol, NorgestimateCilest, Mononessa, Ortho Tri-Cyclen 28, Ortho Tri-Cyclen Lo, Ortho Tri-Cylcen, Ortho-Cyclen +5 more
How Ethinyl Estradiol, Norgestimate interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Norgestimate interactionEthinyl Estradiol, NorgestrelCryselle, Lo/Ovral, Low-Ogestrel, Ogestrel 0.5/50, Ovral
How Ethinyl Estradiol, Norgestrel interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Norgestrel interactionEthinyl Estradiol, LevonogestrelLybrel
How Ethinyl Estradiol, Levonogestrel interacts with CBD Drops Peppermint 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Levonogestrel interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CBD Drops Peppermint 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Broad Spectrum Hemp extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for CBD Drops Peppermint 500 mg, from the product label.
Jane Health
See all Jane Health products- Name
- Barlow Herbal Specialties, LLC
- Street Address
- 110 West 13775 South #9
- City
- Draper
- State
- Utah
- ZipCode
- 84020
- Phone Number
- 866-688-6757
- Web Address
- BarlowHerbal.com
CBD Drops Peppermint 500 mg by Jane Health: Common Questions
Does CBD Drops Peppermint 500 mg by Jane Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is hemp extract the same thing as CBD?
Can I take this if I'm on birth control or hormone therapy?
What does the peppermint do?
Are there any serious side effects I should watch for?
Is it safe to take while breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CBD Drops Peppermint 500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CBD Drops Peppermint 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
CBD Drops Peppermint 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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