Complete CBDA + CBD Oil 25 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Complete CBDA + CBD Oil 25 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Complete CBDA + CBD Oil 25 mg is a dietary supplement by Bluebird Botanicals with 4 active ingredients. Its ingredients are commonly taken for skin and hair care, source of dietary fats (mcts), hydration with coconut water.Based on those ingredients, 1,018 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Broad-Spectrum Hemp, Distillate, Coconut Oil, Fractionated. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals
Ask about any prescription or over-the-counter medication and we check it for interactions with Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This liquid formula contains 4 active ingredients: a proprietary blend, fractionated coconut oil, broad-spectrum hemp distillate, steam-distilled terpenes, and full-spectrum decarboxylated raw hemp aerial parts extract. The hemp components are the main active ingredients, supplying the CBDA and CBD that give the product its name.
Coconut oil serves as a carrier oil and base. The inactive ingredients list is empty — there are no fillers or binders in this formula.
Does it work?
Couldn't assess
The data we hold doesn't establish that this product is effective for any condition. The hemp ingredient is rated insufficient evidence for constipation and eczema.
Coconut oil is similarly unproven for diabetes, high cholesterol, or weight loss. While these ingredients are studied for various uses, we don't have reliable evidence that they work for their intended purposes in supplement form.
How safe is it?
Well-documented data
Coconut oil is generally well tolerated in the amounts found in food, but the data advises caution with concentrated supplement doses unless your doctor approves. Coconut can trigger allergic reactions, including rare severe ones like anaphylaxis, hives, and skin rashes — especially if you have a hypersensitivity to coconut or tree nuts.
Hemp products are generally well tolerated in food amounts, but concentrated extracts and supplements like this one are less studied. Rare serious adverse effects reported with hemp include allergic reactions and anaphylaxis, as well as isolated cases of liver enzyme elevation and hepatitis in very high doses.
There isn't enough data on pregnancy and lactation safety for the hemp ingredients to know whether they're safe during pregnancy or nursing — talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or breastfeeding.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take estrogen or hormone therapy (Moderate interaction risk). Also check if you use blood pressure medications, ACE inhibitors, blood thinners, or any drug that depends on CYP1A2 or CYP3A4 enzymes in your liver, or diabetes medications — all carry Minor interaction risks with the hemp and coconut oil ingredients.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may appeal to you if you're looking for a hemp-based CBD and CBDA supplement, but concentrated hemp extracts are less studied than food amounts, so proceed with caution. If you take medications for hormones, blood pressure, blood clotting, diabetes, or those processed by your liver's CYP enzymes, you'll want to check your specific medications with your doctor or pharmacist before starting.
The same goes if you have a known allergy to coconut or tree nuts.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Complete CBDA + CBD Oil 25 mg, straight from the product label.
| Brand | Bluebird Botanicals |
|---|---|
| Barcode (UPC) | 856888005527 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Feb 22, 2024 |
| DSLD ID | 307854 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 470 mg | -- |
| Coconut Oil, Fractionated | 0 NP | -- |
| Broad-Spectrum Hemp, Distillate | 0 NP | -- |
| Terpenes, Steam-Distilled | 0 NP | -- |
| Full-Spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
CBDA: 12.5 mg per serving CBD: 12.5 mg per serving CBDA: 750 mg per bottle CBD: 750 mg per bottle
Non-synthetic cannabinoids derived from USA-grown hemp.
Total THC less than or equal to 57 mg per container Total THC less than or equal to 0.95 mg per serving
FDA Statement of Identity
Hemp Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA has not evaluated or approved this product for safety or efficacy.
Precautions
Do not exceed 1 mL (2 servings) per day.
Warning: Do not use if pregnant, nursing, or under 18 years of age. Consult your healthcare provider if you are using any prescription medications or have a medical condition.
Warning: Do not use if pregnant, nursing, or under 18 years of age.
This product contains hemp with <= 0.3% Delta-9-THC on a dry-weight basis. Consumption could result in a failed drug test.
Warning: Consuming this product can expose you to chemicals including Delta-9-THC, which is known to the State of California to cause birth defects or other reproductive harm. See: www.P65Warnings.ca.gov/food.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested use: Take 1 serving (15 drops) by mouth, up to twice per day, or as directed by a medical professional.
General Statements
Scan for details
Storage
Store in a cool, dark place.
Seals/Symbols
US Hemp Authority Certified
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.5 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Coconut Oil, Fractionated
- › Broad-Spectrum Hemp, Distillate
- › Terpenes, Steam-Distilled
- › Full-Spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw
Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals Drug Interactions
HelloPharmacist Interaction Report
Bluebird Botanicals' Complete CBDA + CBD Oil 25 mg does interact with medications.
The most serious concern is with hormone therapy (estrogens) — the hemp ingredients may theoretically interfere with how those drugs work due to estrogenic effects seen in animal research. This is rated Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
The hemp ingredients also carry Minor-severity interactions with blood pressure medications (antihypertensive drugs and ACE inhibitors), which may have additive effects and lower your blood pressure further. There's a theoretical Minor risk with blood thinners (anticoagulant/antiplatelet drugs) — animal data suggest hemp might slow clot formation, though human studies of hemp seed oil haven't shown this effect.
Additionally, hemp may theoretically speed up how your liver breaks down certain medications that rely on the CYP1A2 and CYP3A4 enzyme systems, potentially reducing their effectiveness.
Coconut oil in the formula carries a Minor interaction with diabetes medications — theoretically, it might increase the risk of low blood sugar (hypoglycemia). We were unable to check terpenes for interactions, as we hold no data on that ingredient.
Altogether, these interactions span 1,019 individual medications.
Before you start this product, check your exact medications with the search tool on this page, and talk with your doctor or pharmacist if you take hormone therapy, blood pressure drugs, blood thinners, or diabetes medication.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Complete CBDA + CBD Oil 25 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Complete CBDA + CBD Oil 25 mg interact with 1,018 drugs. Click any drug to see the details.
2 of the 4 ingredients in Complete CBDA + CBD Oil 25 mg interact with drugs. Each result below shows which ingredient is responsible. Broad-Spectrum Hemp, Distillate Coconut Oil, Fractionated
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Bazedoxifene Acetate, Conjugated Estrogens interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Conjugated Estrogens, Methyltestosterone interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Cyproterone Acetate, Ethinyl Estradiol interactionDesogestrel, Ethinyl EstradiolDesogen, Marvelon, Marvelon 21, Marvelon 28, Mircette, Ortho-Cept +2 more
How Desogestrel, Ethinyl Estradiol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Desogestrel, Ethinyl Estradiol interactionDrospirenone, EstetrolNextstellis
How Drospirenone, Estetrol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Drospirenone, Estetrol interactionDrospirenone, Ethinyl EstradiolAngeliq, Gianvi, Yasmin
How Drospirenone, Ethinyl Estradiol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Drospirenone, Ethinyl Estradiol interactionEsterified EstrogensEstratab, Menest
How Esterified Estrogens interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Esterified Estrogens interactionEsterified Estrogens, MethyltestosteroneEstratest
How Esterified Estrogens, Methyltestosterone interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Esterified Estrogens, Methyltestosterone interactionEstradiolDivigel, Elestrin, Estrace, Estraderm, Estring, Evamist +6 more
How Estradiol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Estradiol interactionEstradiol, MedroxyprogesteroneDivitren
How Estradiol, Medroxyprogesterone interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Estradiol, Medroxyprogesterone interactionEstradiol, Norethindrone AcetateActivella
How Estradiol, Norethindrone Acetate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Estradiol, Norethindrone Acetate interactionEstradiol, NorgestimateOrtho-Prefest
How Estradiol, Norgestimate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Estradiol, Norgestimate interactionEstradiol, ProgesteroneBijuvanda
How Estradiol, Progesterone interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Estradiol, Progesterone interactionEstrogenEstrogen
How Estrogen interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Estrogen interactionEstroneOrtho-Est
How Estrone interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Estrone interactionEstropipateOgen, Ortho EST
How Estropipate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Estropipate interactionEthiny Estradiol, LevonorgestrelLogynon, Microgynon 30 ED
How Ethiny Estradiol, Levonorgestrel interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethiny Estradiol, Levonorgestrel interactionEthinyl EstradiolEstinyl
How Ethinyl Estradiol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethinyl Estradiol interactionEthinyl Estradiol, DesogestrelApri, Cesia, Cyclessa, Gedarel, Kariva, Linessa +4 more
How Ethinyl Estradiol, Desogestrel interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethinyl Estradiol, Desogestrel interactionEthinyl Estradiol, DrospirenoneYaz
How Ethinyl Estradiol, Drospirenone interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethinyl Estradiol, Drospirenone interactionEthinyl Estradiol, Ethynodiol DiacetateDemulen 1/35, Demulen 1/50, Demulen Compack, Kelnor 1/35, Zovia, Zovia 1/35 +1 more
How Ethinyl Estradiol, Ethynodiol Diacetate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethinyl Estradiol, Ethynodiol Diacetate interactionEthinyl Estradiol, LevonorgestrelAlesse, Alesse 21, Alesse 28, Aviane, Enpresse, Jolessa +18 more
How Ethinyl Estradiol, Levonorgestrel interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethinyl Estradiol, Levonorgestrel interactionEthinyl Estradiol, NorethindroneAranelle, Brevicon, Brevicon .5/35 21 day, Brevicon .5/35 28 day, Brevicon 1/35 21 day, Brevicon 1/35 28 day +50 more
How Ethinyl Estradiol, Norethindrone interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethinyl Estradiol, Norethindrone interactionEthinyl Estradiol, Norethindrone, Ferrous FumarateEstrostep Fe, Femcon FE, Junel Fe 1.5/30, Loestrin Fe, Loestrin Fe 1.5/30, Loestrin Fe 1/20 +3 more
How Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interactionEthinyl Estradiol, NorgestimateCilest, Mononessa, Ortho Tri-Cyclen 28, Ortho Tri-Cyclen Lo, Ortho Tri-Cylcen, Ortho-Cyclen +5 more
How Ethinyl Estradiol, Norgestimate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethinyl Estradiol, Norgestimate interactionEthinyl Estradiol, NorgestrelCryselle, Lo/Ovral, Low-Ogestrel, Ogestrel 0.5/50, Ovral
How Ethinyl Estradiol, Norgestrel interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethinyl Estradiol, Norgestrel interactionEthinyl Estradiol, LevonogestrelLybrel
How Ethinyl Estradiol, Levonogestrel interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ethinyl Estradiol, Levonogestrel interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Complete CBDA + CBD Oil 25 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Broad-Spectrum Hemp, Distillate
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Coconut Oil, Fractionated
Antidiabetes Drugs
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.
Brand information
Manufacturer and brand details for Complete CBDA + CBD Oil 25 mg, from the product label.
Bluebird Botanicals
See all Bluebird Botanicals products- Name
- Bluebird Botanicals
- City
- Louisville
- State
- CO
- ZipCode
- 80027
- Phone Number
- (720) 726-5132
- Web Address
- BluebirdBotanicals.com
Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals: Common Questions
Does Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
Is this product hypoallergenic or free of common allergens?
What does CBDA mean, and how is it different from CBD?
Is this safe to use long-term?
Will this help with my constipation or eczema?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Complete CBDA + CBD Oil 25 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Complete CBDA + CBD Oil 25 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Coconut
Interacts with 86 drugsCoconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses (like skin moisturizing and hydration) h...
Read the full Coconut monograph → Herb & supplement monographHemp
Interacts with 938 drugsHemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...
Read the full Hemp monograph →Sources & How We Checked
Complete CBDA + CBD Oil 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 22 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coconut 10 references
- Teuber SS, Peterson WR. Systemic allergic reaction to coconut (Cocos nucifera) in 2 subjects with hypersensitivity to tree nut and demonstration of cross-reactivity to legumin-like seed storage proteins: new coconut and walnut food allergens. J Allergy Cl PubMed
- Rosado A, Fernandez-Rivas M, Gonzalez-Mancebo E, et al. Anaphylaxis to coconut. Allergy 2002;57(2):182-3. PubMed
- Karmakar PR, Das A, Chatterjee BP. Placebo-controlled immunotherapy with Cocos nucifera pollen extract. Int Arch Allergy Immunol 1994;103(2):194-201. PubMed
- Anagnostou K. Coconut Allergy Revisited. Children (Basel). 2017;4(10). pii: E85. PubMed
- Cifuentes L, Mistrello G, Amato S, et al. Identification of cross-reactivity between buckwheat and coconut. Ann Allergy Asthma Immunol. 2015;115(6):530-2. PubMed
- Michavila Gomez A, Amat Bou M, Gonzalez Cortés MV, Segura Navas L, Moreno Palanques MA, Bartolomé B. Coconut anaphylaxis: Case report and review. Allergol Immunopathol (Madr). 2015;43(2):219-20. PubMed
- 21CFR170.3. U.S. Food and Drug Administration Department of Health and Human Services. Updated April 1, 2017. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=170.3
- Alatawi KA, Alshubaily FA. Coconut products alleviate hyperglycaemic, hyperlipidimic and nephropathy indices in streptozotocin-induced diabetic wistar rats. Saudi J Biol Sci. 2021;28(8):4224-4231. PubMed
- Kruse L, Lor J, Yousif R, Pongracic JA, Fishbein AB. Coconut allergy: Characteristics of reactions and diagnostic predictors in a pediatric tertiary care center. Ann Allergy Asthma Immunol 2021;126(5):562-568.
- Pathmanandavel K, Kaur N, Joshi P, Ford LS. Anaphylaxis and allergy to coconut: An Australian pediatric case series. J Allergy Clin Immunol Pract 2020;8(10):3657-3659. PubMed
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC