Damiana Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Damiana Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Damiana Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Damiana leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Damiana Extract by BulkSupplements.com
Ask about any prescription or over-the-counter medication and we check it for interactions with Damiana Extract by BulkSupplements.com — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Damiana Extract by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: damiana leaf extract. We also include dextrin as an inactive ingredient to stabilize the liquid form.
Does it work?
Couldn't assess
The evidence we hold doesn't establish damiana's effectiveness for sexual dysfunction, asthma, headache, cognitive function, constipation, or depression—the data simply isn't reliable enough to rate it. If you're thinking about damiana for one of these uses, that's a conversation to have with us or your doctor.
How safe is it?
Well-documented data
Damiana appears generally well tolerated in food and tea amounts for most adults, though human safety data are limited. At very high doses (200 grams of extract), rare severe effects like tetanus-like convulsions have been reported.
Pregnancy and breastfeeding: there's not enough safety data either way—avoid it, or talk to your doctor or pharmacist about whether it's right for you.
Meds to double-check
Moderate interaction found
Before you take this, double-check all your antidiabetes drugs (like metformin, insulin, glipizide, or others)—damiana may lower blood sugar and raise the risk of hypoglycemia.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Damiana Extract might appeal to you if you're curious about traditional herbal use, but evidence for most claimed benefits isn't established. If you take diabetes medication, check with us first—the blood sugar interaction matters.
Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or on any prescription.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Damiana Extract, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X002KUPG03 |
| Net contents | 100 Gram(s); 3.5 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 330795 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Damiana Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Damiana Extract 400 mg per serving
Brand IP Statement(s)
Bulksupplements.com Clean & Pure Bulk Supplements
Formulation
Color may vary
Free of: Added sugar, soy, dairy, yeast, gluten
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Always consult a physician before taking any dietary supplement.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 400 mg (about 1/5 tsp) once or twice daily, or as directed by a physician.
General Statements
Use an accurate milligram scale. New
Storage
Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Damiana Extract by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Damiana Extract by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size400 Milligram(s) Dosage formLiquid Servings per container250 Amounts shown are per serving.
Damiana leaf extract
Interacts with86 drugs
Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...
Damiana leaf extract monograph & interactionsOther (inactive) ingredients: Dextrin. These complete the product’s ingredient list but are not active constituents.
Damiana Extract by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Damiana Extract by BulkSupplements.com can interact with antidiabetes drugs.
Since damiana may lower blood sugar, taking it alongside diabetes medications raises the theoretical risk of low blood sugar (hypoglycemia)—dizziness, shakiness, sweating, or confusion. This is a Moderate concern.
Read the full breakdown — every affected drug type, severity by severity
Although we have data on only one drug category, altogether these interactions span 85 individual medications. Use the medication checker on this page to look up your specific diabetes drugs before starting damiana.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Damiana Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Damiana Extract interact with 86 drugs. Click any drug to see the details.
1 of the 1 ingredient in Damiana Extract interact with drugs. Each result below shows which ingredient is responsible. Damiana leaf extract
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Alogliptin, Pioglitazone interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionCanagliflozinInvokana
How Canagliflozin interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Canagliflozin, Metformin Hydrochloride interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Chlorpropamide interactionDapagliflozinFarxiga
How Dapagliflozin interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Dasiglucagon Hydrochloride interactionDulaglutideTrulicity
How Dulaglutide interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Dulaglutide interactionEmpagliflozinJardiance
How Empagliflozin interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Empagliflozin, Metformin Hydrochloride interactionErtugliflozinSteglatro
How Ertugliflozin interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Ertugliflozin interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Ertugliflozin, Metformin Hydrochloride interactionExenatideBydureon, Byetta
How Exenatide interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Exenatide interactionExenatide SyntheticBydureon BCISE
How Exenatide Synthetic interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Exenatide Synthetic interactionGliclazideDiamicron
How Gliclazide interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Gliclazide interactionGlimepirideAmaryl
How Glimepiride interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Glimepiride interactionGlipizideGlucotrol, Glucotrol XL
How Glipizide interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Glipizide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Glipizide, Metformin interactionGlucagonBaqsimi, Glucagon
How Glucagon interacts with Damiana Extract — through 1 ingredient. Tap an ingredient for the detail:
Damiana Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Leaf Extract + Glucagon interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Damiana Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Damiana leaf extract
Antidiabetes Drugs
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.
Brand information
Manufacturer and brand details for Damiana Extract, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Damiana Extract by BulkSupplements.com: Common Questions
Does Damiana Extract by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take damiana if I'm pregnant or breastfeeding?
Does damiana actually help with sexual dysfunction or other conditions?
What happens if I take too much damiana?
Is damiana safe for most adults?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Damiana Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Damiana Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Damiana Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Damiana 2 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC