Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Extra Strength Ideal CBD 25 mg Natural Mint Ingredients & Drug Interactions

by Barlean's

Extra Strength Ideal CBD 25 mg Natural Mint label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Extra Strength Ideal CBD 25 mg Natural Mint against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Extra Strength Ideal CBD 25 mg Natural Mint is a dietary supplement by Barlean's with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp Oil extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's

Ask about any prescription or over-the-counter medication and we check it for interactions with Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: hemp oil extract and cannabinoid. You're also getting MCT oil (a type of fat used as a carrier), full spectrum hemp extract, and natural mint flavor as inactive ingredients that give the supplement its form and taste.

The hemp oil extract is the ingredient we have the most interaction data on; the cannabinoid content we weren't able to assess for drug interactions.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hemp product and its label doesn't state a use — see Hemp's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on hemp oil extract for the conditions it's marketed for — constipation, eczema (atopic dermatitis), and high cholesterol (familial hypercholesterolemia) — isn't established in our data. All these uses are rated as having insufficient reliable evidence to rate its effectiveness.

That doesn't mean it doesn't work, but the science we hold doesn't confirm it for these purposes yet.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods are generally well tolerated in normal amounts, but concentrated extracts and supplements like this one are less studied, so caution is advised. In larger doses or supplement form, hemp seed oil appears well tolerated overall.

Rare serious side effects have been reported, including allergic reactions (hives, facial swelling, shortness of breath, anaphylaxis), and very rare cases of elevated liver enzymes and hepatitis have occurred in children given high-dose hemp extract. Allergy to hemp seed is uncommon but documented.

There is no pregnancy or lactation safety information on file for this product's ingredients.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product with your doctor or pharmacist if you take estrogen therapy or hormonal birth control (Moderate interaction risk), blood pressure medications like ACE inhibitors or other antihypertensives (Minor risk), blood thinners like warfarin or clopidogrel (Minor risk), or drugs metabolized through your liver's CYP1A2 or CYP3A4 systems (Minor risk — your pharmacist can tell you which ones). The cannabinoid ingredient has no documented interaction data we could assess.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take hormones (estrogen therapy or birth control), blood pressure medications, or blood thinners, check your exact prescriptions with your doctor or pharmacist before starting this product. Hemp extract is generally well tolerated at food amounts, but concentrated supplements like this one have less safety data behind them.

Talk it over with your own healthcare provider to decide if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Extra Strength Ideal CBD 25 mg Natural Mint, straight from the product label.

Brand Barlean's
Barcode (UPC) 705875800976
Net contents 1.5 Fluid Ounce(s); 45 mL
Market status On market
Date entered into DSLD Mar 24, 2020
DSLD ID 216086
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
45
UPC/BARCODE
705875800976
IngredientAmount% DV
Calories10 Calorie(s)--
Total Fat1 Gram(s)1%
Hemp Oil extract35 mg--
Cannabinoid25 mg--

Other ingredients: MCT Oil, Full Spectrum Hemp Extract, natural Mint flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions for use: Place 20 drops (approximately 3/4 full dropper) under the tongue as needed.

Shake well before use

General Statements

Carpe CBDiem!

go.Barleans.com/Lookitup

estd 1989

Get to know your bottle. For sourcing, testing results and more, scan or visit go.Barleans.com/Lookitup

Your trusted source

At Barlean's, our family has been making healthy oils for nearly 30 years. We're big believers in the power of nature, and when it comes to powerful compounds, there are few that compare to Cannabidiol (CBD).

From our family to yours-Carpe CBDiem!

Dropper Included

Product of U.S.A.

Precautions

Warning: Keep out of reach of children; not intended for use under the age of 18.

Consult your physician if you have a medical condition or are taking any medications. Do not take if you are pregnant or nursing.

Formula

Less than 0.3% THC

25 mg CBD per serving

Hemp oil 1,125 mg CBD

We create our Extra Strength Ideal CBD using the industrial hemp from American farms. Not only is it sourced close to home, it includes a full spectrum of cannabinoids and other micronutrients.

Made from U.S. Grown Hemp Full Spectrum

Formulation

BPA and Phthalate free bottle

No artificial ingredients

Third party lab tested

Non-GMO Gluten free

Vegan

FDA Statement of Identity

Dietary Supplement

Storage

No refrigeration required

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Extra Strength Ideal CBD 25 mg Natural Mint label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Hemp Oil extract

Interacts with
938 drugs
35 mg per serving

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Hemp Oil extract monograph & interactions

Cannabinoid

25 mg per serving

Other (inactive) ingredients: MCT Oil, Full Spectrum Hemp Extract, Natural Mint flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's Drug Interactions

Want to check YOUR meds against Extra Strength Ideal CBD 25 mg Natural Mint?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

Hemp Oil extract 938

Individual Drug Interactions

The ingredients in Extra Strength Ideal CBD 25 mg Natural Mint interact with 938 drugs. Click any drug to see the details.

1 of the 2 ingredients in Extra Strength Ideal CBD 25 mg Natural Mint interact with drugs. Each result below shows which ingredient is responsible. Hemp Oil extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Extra Strength Ideal CBD 25 mg Natural Mint with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Hemp Oil extract6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Hemp Oil extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Extra Strength Ideal CBD 25 mg Natural Mint, from the product label.

Barlean's

See all Barlean's products
Name
Barlean's
City
Ferndale
State
WA
ZipCode
98248
Phone Number
800-445-3529
Web Address
barleans.com
Pharmacist Counseling Corner

Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's: Common Questions

Does Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's interact with any medications?
Yes. Based on its ingredients, Extra Strength Ideal CBD 25 mg Natural Mint has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Extra Strength Ideal CBD 25 mg Natural Mint contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product have any serious side effects?
Serious side effects are rare. The main ones reported are allergic reactions (hives, facial swelling, shortness of breath, or anaphylaxis in people sensitive to hemp seed) and very rare cases of liver enzyme elevation and hepatitis in children given high-dose hemp extract. Allergies to hemp seed are uncommon but can occur. Talk to your doctor if you have a history of allergies.
Can I take this while I'm on birth control?
Not without checking first. Hemp may interfere with estrogen-based hormonal birth control because of its estrogenic effects shown in animal research. The interaction is rated Moderate, so contact your doctor or pharmacist before starting this product to discuss whether it's safe for you.
Is this safe if I take blood pressure medication?
Possibly, but you need to check with your own doctor or pharmacist. Hemp seed protein may have additive effects with blood pressure drugs and ACE inhibitors, which could lower your blood pressure too much. Don't start this without confirming your specific medications are compatible.
Does this product actually work for what it claims?
The evidence isn't established in our data. Uses like relieving constipation, treating eczema, or lowering cholesterol are all rated as having insufficient reliable evidence. That doesn't mean it doesn't help, but the science we hold doesn't confirm these benefits yet.
Can I take this while breastfeeding?
We don't have safety data on file for this product during breastfeeding. Talk with your doctor or pharmacist — they can review your personal health situation and help you decide whether it's safe for you and your baby.
Is there any way this could make my other medications less effective?
Yes. Hemp may speed up how your liver breaks down drugs that use the CYP1A2 and CYP3A4 enzyme systems, potentially making those medications less effective. Your pharmacist can tell you if any of your prescriptions are affected by checking the list on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Extra Strength Ideal CBD 25 mg Natural Mint is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Extra Strength Ideal CBD 25 mg Natural Mint label
Go deeper

The Full Monographs Behind Extra Strength Ideal CBD 25 mg Natural Mint’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hemp

Interacts with 938 drugs

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...

Read the full Hemp monograph →
Sources

Sources & How We Checked

Extra Strength Ideal CBD 25 mg Natural Mint's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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