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Dietary supplement

GABA-Pro Ingredients & Drug Interactions

by Bioclinic Naturals

GABA-Pro label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking GABA-Pro against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

GABA-Pro is a dietary supplement by Bioclinic Naturals with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 419 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gamma Amino Butyric Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against GABA-Pro by Bioclinic Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with GABA-Pro by Bioclinic Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of GABA-Pro by Bioclinic Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

GABA-Pro contains one active ingredient: gamma-aminobutyric acid (GABA), a naturally occurring compound in the brain. The capsule also holds rice powder, magnesium stearate, and silica as inactive ingredients to hold everything together and keep the powder flowing smoothly.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gamma-aminobutyric Acid (gaba)'s own graded uses on its monograph.

Why this rating?
  • The label markets this product for: relaxation and calming without drowsiness.
  • We looked for evidence on: Anxiety, Stress, Post-traumatic stress disorder (PTSD), Nervous tension, Neurotransmitter balance, Mental relaxation.
  • The closest evidence on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Post-traumatic stress disorder (PTSD).

The evidence for GABA supplementation is thin. Our data shows insufficient reliable evidence to rate it for anxiety, ADHD, athletic performance, cerebral palsy, or chronic bronchitis.

Because the science doesn't establish whether it works for these uses, you should have realistic expectations and talk with your doctor about whether this product is right for your situation.

The evidence, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

GABA is generally well tolerated when taken by mouth in the short term, though long-term safety hasn't been well studied. The most common side effects reported are drowsiness, upset stomach, minor throat burning, muscle weakness, and nausea.

The product carries a caution label because we don't have enough long-term safety data. Not enough safety information exists to recommend GABA during breastfeeding, so it's best to avoid it unless your doctor advises otherwise.

Pregnancy safety data isn't on file for this ingredient; talk with your own doctor or pharmacist before using it if you're pregnant or planning to become pregnant.

Side effects, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gamma-aminobutyric Acid (gaba).
  • The most serious interaction on file is rated Moderate.
  • For scale: 419 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking GABA-Pro, double-check with your own doctor or pharmacist if you're on any blood pressure medication (antihypertensives)—GABA may lower your blood pressure too much. Also check if you take any central nervous system depressants, including sleep aids, anti-anxiety drugs, or opioids, because GABA might add to their drowsy or sedative effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

GABA-Pro is a single-ingredient supplement with limited evidence of effectiveness and some important drug interactions to watch for—especially with blood pressure and sedative medications. If you take any prescription or over-the-counter drugs, check them against this product with your own doctor or pharmacist before starting.

It may be worth considering if your healthcare provider thinks GABA is right for you, but go in with realistic expectations about what the evidence shows.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GABA-Pro, straight from the product label.

Brand Bioclinic Naturals
Barcode (UPC) 629022092840
Net contents 90 Vegetarian Capsule(s); 100 mg
Market status On market
Date entered into DSLD Apr 25, 2013
DSLD ID 20826
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GABA-Pro by Bioclinic Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
629022092840
IngredientAmount% DV
Gamma Amino Butyric Acid200 mg--

Other ingredients: Vegetarian capsule, Rice powder, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

GABA (gamma amino butyric acid) is an important neurotransmitter in the brain and is known to be the brain's natural calming agent.*

Bioclinic Naturals products are guaranteed to meet or exceed Good Manufacturing Practices (GMP) of the Canadian Government and the Therapeutic Goods Administration (TGA) regulations of Australia-among the world's highest standards for natural products.

It is naturally manufactured via a fermentation process that utilizes Lactobacillus hilgardii, the bacterium used to ferment vegetables in the preparation of the traditional Korean dish known as kimchi.

Recyclable container.

Calming Effect*

LOT206460 EXP AU 2013

PRODUCT OF CANADA

Brand IP Statement(s)

GABA-Pro(TM) helps in proper functioning of the brain and nerve cells, which produces a focusing and calming effect. GABA-Pro(TM) can quickly promote relaxation and ease nervous tension without causing drowsiness.*

Pharma GABA(R) is a registered trademark of Pharma Foods International Co., Ltd (Japan).

Formulation

Contains no preservatives, colors or sweeteners; no dairy, gluten, soy or wheat.

Precautions

Sealed for your protection. Do not use if seal is broken.

Seals/Symbols

PURE POTENT TRUSTED TESTED

{recycle}

Formula

GABA-Pro(TM) contains Pharma GABA(R), a naturally-sourced and superior form to that of synthetic GABA.

100% Natural GABA

Storage

For freshness, store in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested Usage: 1-2 capsules up to 3 times per day or as directed by a health care professional.

FDA Statement of Identity

DIETARY SUPPLEMENT

General

R1

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

GABA-Pro by Bioclinic Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

GABA-Pro label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in GABA-Pro by Bioclinic Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Gamma Amino Butyric Acid

Interacts with
419 drugs
200 mg per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

Gamma Amino Butyric Acid monograph & interactions

Other (inactive) ingredients: Vegetarian capsule, Rice powder, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

GABA-Pro by Bioclinic Naturals Drug Interactions

Want to check YOUR meds against GABA-Pro?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
419Drugs
172 Moderate 247 Minor

Ingredients driving the most interactions

Gamma Amino Butyric Acid 419

Individual Drug Interactions

The ingredients in GABA-Pro interact with 419 drugs. Click any drug to see the details.

1 of the 1 ingredient in GABA-Pro interact with drugs. Each result below shows which ingredient is responsible. Gamma Amino Butyric Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in GABA-Pro with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gamma Amino Butyric Acid2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
Gamma Amino Butyric Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for GABA-Pro, from the product label.

Bioclinic Naturals

See all Bioclinic Naturals products
Name
Bioclinic Naturals(TM) U.S.
Street Address
1111-80th St. SW, Ste. 100
City
Everett
State
WA
ZipCode
98203
Phone Number
1-877-433-9860
Web Address
www.bioclinicnaturals.com
Pharmacist Counseling Corner

GABA-Pro by Bioclinic Naturals: Common Questions

Does GABA-Pro by Bioclinic Naturals interact with any medications?
Yes. Based on its ingredients, GABA-Pro has a known interaction with 419 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
GABA-Pro contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is GABA and what's it supposed to do?
GABA is gamma-aminobutyric acid, a chemical messenger in your brain that helps calm nerve activity. People take GABA supplements hoping it might help with anxiety, sleep, ADHD, and athletic performance, but the evidence doesn't reliably support any of those uses yet.
What side effects should I watch for?
The most common ones reported are drowsiness, upset stomach, minor throat burning, muscle weakness, and nausea. GABA seems to be well tolerated overall, but we don't have good long-term safety data, so nobody really knows what happens with years of use.
Can I take this while breastfeeding?
No, not enough safety information exists—it's best to avoid it while breastfeeding unless your doctor advises otherwise. There's not enough data to know either way, so talk with your own doctor or pharmacist for personalized advice.
Is it safe to take GABA if I'm on a sleep aid?
That's something to check with your doctor or pharmacist first. GABA might add extra drowsiness on top of what your sleep aid already does, though we're not sure how much of a real-world concern that is.
Does this product have any fillers or junk in it?
The capsule itself is vegetarian, and it contains rice powder, magnesium stearate, and silica—all standard inactive ingredients that help keep the supplement stable and easy to take. There are no other active ingredients.
Will GABA help me with anxiety?
The evidence right now is insufficient to say whether it works for anxiety. If you're thinking about trying it, talk with your own doctor or pharmacist to see if it makes sense for you alongside your other treatments.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GABA-Pro label
Go deeper

The Full Monographs Behind GABA-Pro’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph →
Sources

Sources & How We Checked

GABA-Pro's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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