Interactions on record — worth a quick check against your medications. Based on 6 of 7 ingredients. Check your meds →
Dietary supplement

Glucose Care with Cinnulin PF Ingredients & Drug Interactions

by Patient One 1 MediNutritionals

Glucose Care with Cinnulin PF label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glucose Care with Cinnulin PF against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glucose Care with Cinnulin PF is a dietary supplement by Patient One 1 MediNutritionals with 7 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 556 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, Vanadium, Chromium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Glucose Care with Cinnulin PF by Patient One 1 MediNutritionals

Ask about any prescription or over-the-counter medication and we check it for interactions with Glucose Care with Cinnulin PF by Patient One 1 MediNutritionals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Glucose Care with Cinnulin PF by Patient One 1 MediNutritionals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 5 of its 7 active ingredients.
  • “Sugar Balance Proprietary Blend” is a proprietary blend — the label gives one combined amount (500.06 mg) without saying how much of each component you get.

Glucose Care with Cinnulin PF contains seven active ingredients. Vitamin B6 supports energy use and nerve health.

Thiamine (vitamin B1) is needed to convert food into energy. Manganese is a mineral involved in bone health and metabolism.

Zinc supports immune function and wound healing. Chromium helps regulate blood sugar.

Vanadium is a trace mineral under study for metabolic effects. The product also contains a proprietary blend called Sugar Balance and the branded cinnamon extract Cinnulin PF.

The capsule is filled with inactive ingredients including rice flour, vegetable cellulose, and leucine.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Blood sugar support and glucose metabolism.
  • We looked for evidence on: Chromium deficiency, Diabetes, Dyslipidemia, Insulin sensitivity, Blood glucose control.
  • The strongest evidence on file: Chromium is rated "Likely Effective" for Chromium deficiency (Natural Medicines).
  • Also on file: Chromium is rated "Possibly Effective" for Diabetes.
  • Also on file: Zinc is rated "Possibly Effective" for Diabetes.

Vitamin B6 is effective for B6 deficiency and sideroblastic anemia (a type of blood disorder), and it's possibly effective for pregnancy-related nausea. Thiamine is effective for thiamine deficiency and Wernicke-Korsakoff syndrome (a serious neurological condition from thiamine lack).

Manganese deficiency is effectively treated with manganese; its use for other conditions like arthritis or hay fever lacks reliable evidence. Zinc is effective for zinc deficiency and Wilson disease (a copper storage disorder), and it's possibly effective for acne and age-related macular degeneration.

Chromium is likely effective for chromium deficiency and possibly effective for type 2 diabetes, though evidence is limited. Vanadium is likely effective for vanadium deficiency; evidence for its use in diabetes is sparse.

We hold no effectiveness data for Cinnulin PF.

The evidence, ingredient by ingredient Vitamin B6 Thiamine Manganese Zinc Chromium Vanadium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is well tolerated in doses under 100 mg daily, but high doses over time can damage nerves (sensory neuropathy). Use in pregnancy for morning sickness is done only under medical guidance.

Thiamine is generally very safe by mouth and is considered likely safe in pregnancy and lactation. Manganese is well tolerated at normal doses but high doses carry a rare risk of nerve damage resembling Parkinson disease and liver injury.

Avoid high-dose manganese in pregnancy unless advised by your doctor. Zinc is well tolerated below 40 mg daily; higher doses increase the rare risk of copper deficiency.

Chromium is usually well tolerated at typical doses but has limited safety data for high or long-term use. Vanadium at normal dietary amounts is fine, but supplement doses should be avoided in pregnancy and breastfeeding due to insufficient safety data.

Vanadium above the safe upper limit may cause stomach upset or kidney damage at high doses.

Side effects, ingredient by ingredient Vitamin B6 Thiamine Manganese Zinc Chromium Vanadium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Manganese, Vanadium, Chromium, Vitamin B6, Thiamine, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; Parkinson's medications.
  • For scale: 556 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against these before taking this product: seizure drugs (phenytoin, phenobarbital), insulin and diabetes medications, blood pressure drugs, antibiotics (quinolones, tetracyclines, cephalexin), HIV medications (ritonavir, integrase inhibitors, bictegravir combinations), thyroid medication (levothyroxine), blood thinners and antiplatelet drugs, penicillamine, amiodarone, and antipsychotic medications. These span Moderate or Minor severity interactions documented in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines nutrients that support blood sugar metabolism and overall health. If you take seizure medications, blood pressure drugs, insulin, diabetes pills, antibiotics, blood thinners, or HIV medications, check your exact prescriptions with our tool before starting.

Pregnant or breastfeeding—especially regarding vanadium—talk with your pharmacist or doctor about whether this is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glucose Care with Cinnulin PF, straight from the product label.

Brand Patient One 1 MediNutritionals
Barcode (UPC) 853959004267
Net contents 120 Vegetable Capsule(s)
Market status On market
Date entered into DSLD May 22, 2021
DSLD ID 249300
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glucose Care with Cinnulin PF by Patient One 1 MediNutritionals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
40
UPC/BARCODE
853959004267
IngredientAmount% DV
Vitamin B650 mg2941%
Thiamine50 mg4167%
Manganese5 mg217%
Zinc30 mg273%
Chromium600 mcg1714%
Vanadium0 NP--
Sugar Balance Proprietary Blend500.06 mg--
Cinnulin PF0 NP--

Other ingredients: Rice Flour, Vegetable Cellulose, Leucine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Vegetarian

Gluten free Non-GMO Free of: milk, egg, fish, peanuts, crustacean shellfish, soy, tree nuts, wheat, yeast and gluten. Free of ingredients derived from GMOs.

Sugar Balance Formula

Suggested/Recommended/Usage/Directions

Suggested Use: Take 3 capsules daily in divided doses with meals as a dietary supplement, or as directed by your health practitioner.

Precautions

Caution: If pregnant, nursing, or taking medications, consult your health practitioner before use.

Discontinue use and consult your health practitioner if any adverse reactions occur.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Chromemate, a biologically active oxygen-coordinated niacin-bound chromium complex, is a registered trademark of InterHealth N.I. Cinnulin PF is a trademark of IN ingredients Inc. TRAACS is a registered trademark of Albion Labs, Inc.

General Statements

BPA free

Exclusive Professional Formulas

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glucose Care with Cinnulin PF by Patient One 1 MediNutritionals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glucose Care with Cinnulin PF label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glucose Care with Cinnulin PF by Patient One 1 MediNutritionals

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
50 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Thiamine

Interacts with
3 drugs
50 mg per serving Form: Thiamine Hydrochloride, Vitamin B1

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...

Thiamine monograph & interactions

Manganese

Interacts with
83 drugs
5 mg per serving Form: TRAACS Manganese Glycinate Chelate

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get...

Manganese monograph & interactions

Zinc

Interacts with
67 drugs
30 mg per serving Form: TRAACS Zinc Glycinate Chelate

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but suppleme...

Zinc monograph & interactions

Chromium

Interacts with
178 drugs
600 mcg per serving Form: Chromemate Chromium Polynicotinate

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

Sugar Balance Proprietary Blend

500.06 mg per serving

Other (inactive) ingredients: Rice Flour, Vegetable Cellulose, Leucine. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glucose Care with Cinnulin PF by Patient One 1 MediNutritionals Drug Interactions

Want to check YOUR meds against Glucose Care with Cinnulin PF?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
556Drugs
517 Moderate 39 Minor

Ingredients driving the most interactions

Vitamin B6 210
Vanadium 208
Chromium 178
Manganese 83
Zinc 67

Individual Drug Interactions

The ingredients in Glucose Care with Cinnulin PF interact with 556 drugs. Click any drug to see the details.

6 of the 7 ingredients in Glucose Care with Cinnulin PF interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 Vanadium Chromium Manganese Zinc Thiamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glucose Care with Cinnulin PF with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Vanadium2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that the sodium orthovanadate form of vanadium prolongs clotting time, likely through inhibition of thrombin and factor Xa.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
A few very small clinical studies in patients with type 2 diabetes show that the vanadyl sulfate form of vanadium increases insulin sensitivity and might lower blood glucose levels.

Likelihood Probable Evidence B
Vanadium full monograph & interactions

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions

Manganese3 drug types · 83 drugs

Antipsychotic Drugs

Theoretically, the risk for manganese toxicity might increase when taken with antipsychotic drugs.
Hallucinations and behavioral changes have been reported in a patient with liver disease who was taking haloperidol and manganese. Researchers speculate that taking manganese along with haloperidol, phenothiazine-derivatives, or other antipsychotic medications might increase the risk of manganese toxicity in some patients.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, manganese might reduce the absorption of quinolone antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced quinolone absorption have been reported between quinolones and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, manganese might reduce the absorption of tetracycline antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced tetracycline absorption have been reported between tetracyclines and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Manganese full monograph & interactions

Zinc10 drug types · 67 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Theoretically, zinc might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after zinc containing products.

Likelihood Probable Evidence D
Cephalexin (Keflex)

Zinc might decrease cephalexin levels by chelating with cephalexin in the gut and preventing its absorption.
A pharmacokinetic study shows that zinc sulfate 250 mg taken concomitantly with cephalexin 500 mg decreases peak levels of cephalexin by 31% and reduces the exposure to cephalexin by 27%. Also, taking zinc sulfate 3 hours before cephalexin decreases peak levels of cephalexin by 11% and reduces the exposure to cephalexin by 18%. By decreasing cephalexin levels, zinc might increase the risk of treatment failure. This effect does not occur when zinc is taken 3 hours after the cephalexin dose. To avoid an interaction, advise patients take zinc sulfate 3 hours after taking cephalexin.

Likelihood Probable Evidence B
Cisplatin (Platinol-Aq)

Theoretically, zinc might interfere with the therapeutic effects of cisplatin.
Animal research suggests that zinc stimulates tumor cell production of the protein metallothionein, which binds and inactivates cisplatin. It is not known whether zinc supplements or high dietary zinc intake can cause clinically significant interference with cisplatin therapy. Cisplatin might also increase zinc excretion.

Likelihood Possible Evidence D
Integrase Inhibitors

Theoretically, taking zinc along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Zinc is a divalent cation. Pharmacokinetic studies have shown that other divalent cations such as calcium and iron can decrease blood levels of the integrase inhibitor dolutegravir through chelation.

Likelihood Possible Evidence D
Penicillamine (Cuprimine, Depen)

Zinc might reduce the levels and clinical effects of penicillamine.
By forming an insoluble complex with penicillamine, zinc interferes with penicillamine absorption and activity. Zinc supplements reduce the efficacy of low-dose penicillamine (0.5-1 gram/day), but do not seem to affect higher doses (1-2.75 gram/day), provided dosing times are separated. Advise patients to take zinc and penicillamine at least 2 hours apart.

Likelihood Probable Evidence B
Quinolone Antibiotics

Zinc can decrease the levels and clinical effects of quinolones antibiotics.
Quinolones form complexes with zinc in the gastrointestinal tract, reducing absorption of both the quinolone and zinc if taken at the same time. Advise patients to take these drugs at least 2 hours before, or 4-6 hours after, zinc supplements.

Likelihood Probable Evidence B
Ritonavir (Norvir)

Zinc modestly reduces levels of ritonavir.
Clinical research shows that zinc might reduce serum ritonavir levels by chelating with ritonavir in the gut and preventing its absorption. In patients with HIV, ritonavir is taken with atazanavir to prevent the metabolism and increase the effects of atazanavir. A pharmacokinetic study shows that, in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate (Solvazinc tablets) 125 mg as a single dose or as multiple daily doses for 2 weeks reduces plasma levels of ritonavir by about 16%. However, atazanavir levels still remains high enough to prevent HIV virus replication. Therefore, the decrease in ritonavir levels is not likely to be clinically significant.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Zinc might reduce levels of tetracycline antibiotics.
Tetracyclines form complexes with zinc in the gastrointestinal tract, which can reduce absorption of both the tetracycline and zinc when taken at the same time. Taking zinc sulfate 200 mg with tetracycline reduces absorption of the antibiotic by 30% to 40%. Demeclocycline and minocycline cause a similar interaction. However, doxycycline does not seem to interact significantly with zinc. Advise patients to take tetracyclines at least 2 hours before, or 4-6 hours after, zinc supplements to avoid any interactions.

Likelihood Probable Evidence B
Amiloride (Midamor)

Amiloride can modestly reduce zinc excretion and increase zinc levels.
Clinical research shows that amiloride can reduce urinary zinc excretion, especially at doses of 10 mg per day or more. This zinc-sparing effect can help to counteract zinc losses caused by thiazide diuretics, but it is unlikely to cause zinc toxicity at usual amiloride doses. The other potassium-sparing diuretics, spironolactone (Aldactone) and triamterene (Dyrenium), do not seem to have a zinc-sparing effect.

Likelihood Probable Evidence B
Atazanavir (Reyataz)

Zinc modestly reduces levels of atazanavir, although this effect does not seem to be clinically significant.
Clinical research shows that zinc might decrease serum atazanavir levels by chelating with atazanavir in the gut and preventing its absorption. Although a single dose of zinc sulfate (Solvazinc tablets) 125 mg orally does not affect atazanavir concentrations in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate 125 mg daily for 2 weeks reduces plasma levels of atazanavir by about 22% in these patients. However, despite this decrease, atazanavir levels still remain at high enough concentrations for the prevention of HIV virus replication.

Likelihood Probable Evidence B
Zinc full monograph & interactions

Thiamine1 drug type · 3 drugs

Trimethoprim (Proloprim)

Trimethoprim might increase blood levels of thiamine.
In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations.

Likelihood Probable Evidence B
Thiamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glucose Care with Cinnulin PF, from the product label.

Patient One 1 MediNutritionals

See all Patient One 1 MediNutritionals products
Name
MediNutritionals Research LLC
City
Hauppage
State
NY
ZipCode
11788
Phone Number
(631) 390-9669
Web Address
patientoneformulas.com
Pharmacist Counseling Corner

Glucose Care with Cinnulin PF by Patient One 1 MediNutritionals: Common Questions

Does Glucose Care with Cinnulin PF by Patient One 1 MediNutritionals interact with any medications?
Yes. Based on its ingredients, Glucose Care with Cinnulin PF has a known interaction with 556 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glucose Care with Cinnulin PF contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
Thiamine is considered likely safe in pregnancy at recommended amounts. Vitamin B6 is used for pregnancy-related nausea only under a doctor's guidance. However, vanadium should be avoided in pregnancy because we don't have enough safety data. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy, as you'll want personalized advice on all the ingredients.
Will this help my blood sugar?
Chromium and vanadium are both studied for blood sugar support, though the evidence for each is limited. Chromium is possibly effective for type 2 diabetes, and vanadium's deficiency can be corrected, but we don't have strong data on how well this product works for blood sugar control overall. Your doctor or pharmacist can tell you whether it fits your situation.
What's Cinnulin PF?
Cinnulin PF is a branded cinnamon extract included in this formula. We don't hold interaction or safety data for it, so we can't tell you how it works or what effects it might have. If you have questions specific to this ingredient, ask your pharmacist.
Are there any side effects I should know about?
At normal supplement doses, these ingredients are generally well tolerated. Zinc may cause nausea, a metallic taste, or stomach cramps at higher doses. Vitamin B6 at high doses over time can cause nerve damage. Vanadium above safe levels can cause stomach upset. If you notice anything unusual after starting, let your pharmacist know.
Can I take this with my other vitamins?
That depends on what's in them. Zinc can interfere with absorption of certain antibiotics if taken at the same time, and chromium can lower levothyroxine (thyroid medication) levels. Your pharmacist can check your whole supplement and medication routine to make sure there are no conflicts.
Is this safe while breastfeeding?
Thiamine is needed while breastfeeding and is safe at recommended amounts under your provider's guidance. Vanadium should be avoided while breastfeeding because we don't have enough safety data. Talk with your doctor or pharmacist before taking this product if you're nursing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glucose Care with Cinnulin PF label
Go deeper

The Full Monographs Behind Glucose Care with Cinnulin PF’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Thiamine

Interacts with 3 drugs

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get enough from food, but supplements are clear...

Read the full Thiamine monograph → Herb & supplement monograph

Manganese

Interacts with 83 drugs

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get enough from a normal diet. Supplements m...

Read the full Manganese monograph → Herb & supplement monograph

Zinc

Interacts with 67 drugs

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but supplements can help correct or prevent a defici...

Read the full Zinc monograph → Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph → Herb & supplement monograph

Vanadium

Interacts with 208 drugs

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athletic performance are not well proven, and...

Read the full Vanadium monograph →
Sources

Sources & How We Checked

Glucose Care with Cinnulin PF's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 216 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
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Manganese 21 references
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See these in context on the Chromium monograph →

Vanadium 15 references
  1. Harland BF, Harden-Williams BA. Is vanadium of human nutritional importance yet? J Am Diet Assoc 1994;94:891-4. PubMed
  2. Sitprija V, Tungsanga K, Tosukhowong P, et al. Metabolic problems in northeastern Thailand: possible role of vanadium. Mineral Electrolyte Metab 1998;19:51-6.
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  8. Goldfine AB, Simonson DC, Folli F, et al. Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. J Clin Endocrinol Metab 1995;80:3311-20. PubMed
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See these in context on the Vanadium monograph →

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