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Dietary supplement

Glutamine Stack Ingredients & Drug Interactions

by Tokkyo Nutrition

Glutamine Stack label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glutamine Stack against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glutamine Stack is a dietary supplement by Tokkyo Nutrition with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glutamine Stack Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glutamine Stack by Tokkyo Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Glutamine Stack by Tokkyo Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glutamine Stack by Tokkyo Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Glutamine Stack Blend” is a proprietary blend — the label gives one combined amount (5,000 mg) without saying how much of each component you get.

Glutamine Stack contains 3 active ingredients, all variations of the amino acid glutamine: L-Glutamine, L-Glutamine Ethyl Ester, and L-Glutamine Alpha Keto Glutarate. Glutamine is a building block your body uses for muscle repair, immune function, and gut health.

This powder has no inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle recovery and energy enhancement.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Wound healing, Critical illness (trauma), Burns — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for HIV/AIDS-related wasting (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma), Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Burns.

The two glutamine forms we have data on—L-Glutamine and L-Glutamine Ethyl Ester—are rated Effective for sickle cell disease. They're rated Possibly Effective for HIV/AIDS-related wasting, recovery after surgery, and critical illness from trauma.

We don't hold effectiveness data for L-Glutamine Alpha Keto Glutarate.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Glutamine and L-Glutamine Ethyl Ester are generally well tolerated in healthy adults. The most common side effects are digestive: belching, bloating, constipation, diarrhea, flatulence, and nausea.

High doses (10–30 grams daily) in clinical trials have also caused these GI symptoms, plus headache and, rarely, dizziness. A small number of people with bipolar disorder have reported mania or hypomania on glutamine, and it may have neurological effects in people with existing neurological conditions.

If you have kidney or liver disease, use only under medical supervision. During pregnancy and lactation, the data shows it's likely safe, but there isn't enough reliable safety information to be certain—talk with your doctor or pharmacist for personalized advice.

We don't have safety data on file for L-Glutamine Alpha Keto Glutarate.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant (seizure) medications, check your exact drugs with the search tool on this page. The Moderate interaction with anticonvulsants is the only documented concern we have for the ingredients we could check—though the risk is theoretical and unconfirmed in human cases, it's important to verify your specific medication before starting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine Stack is designed to support muscle recovery and immune function and is well tolerated by most healthy people. If you take seizure medication, check your specific drugs before starting—the glutamine forms may theoretically interfere with them, though it hasn't happened in reported cases.

If you have kidney or liver disease, bipolar disorder, or a neurological condition, talk with your doctor or pharmacist before adding this.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutamine Stack, straight from the product label.

Brand Tokkyo Nutrition
Barcode (UPC) 896896002644
Net contents 8.82 Oz(s); 250 Gram(s)
Market status On market
Date entered into DSLD Aug 31, 2018
DSLD ID 180503
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutamine Stack by Tokkyo Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
10 Gram(s)
Servings per container
50
UPC/BARCODE
896896002644
IngredientAmount% DV
L-Glutamine0 NP--
Glutamine Stack Blend5000 mg--
L-Glutamine Alpha Keto Glutarate0 NP--
L-Glutamine Ethyl Ester0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Allergen Warning: Manufactured in a facility that processes milk, soy and egg proteins, nuts, and other tree nuts and wheat.

Warning: Consult your physician before using this product. This product is only intended to be consumed by healthy adult males 18 years of age or older.

Pregnant or lactating women should consult their health care professional before using this product.

Read all label information and warnings, do not exceed recommended dosage.

If you are a professional or amateur athlete subject to performance enhancing substance testing, do not use this product unless cleared by your sanctioning body as it may cause a false reactive result for a urine or blood drug test.

Formula

This product is only intended to be consumed by healthy adult males 18 years of age or older.

Formulation

Zero calories 0 cal per serving

General Statements

Muscle and energy enhancing compound

Support strength Muscle recovery Pharmaceutical grade

At Tokkyo Nutrition, our pharmaceutical-grade Glutamine Stack is one of the best weight lifting supplements you'll find on the market for strength support and safe, minimized recovery times.

Seals/Symbols

Made in USA

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions for use: As a dietary supplement use (1) to (2) scoops in 8-12 oz of water or your favorite sports drink 20 minutes prior to work out. For best results take another (1) to (2) scoops after your workout.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glutamine Stack by Tokkyo Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glutamine Stack label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glutamine Stack by Tokkyo Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.

Glutamine Stack Blend

Interacts with
50 drugs
5000 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

Glutamine Stack Blend monograph & interactions
Interaction report

Glutamine Stack by Tokkyo Nutrition Drug Interactions

Want to check YOUR meds against Glutamine Stack?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Glutamine Stack Blend 50

Individual Drug Interactions

The ingredients in Glutamine Stack interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Glutamine Stack interact with drugs. Each result below shows which ingredient is responsible. Glutamine Stack Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in Glutamine Stack with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glutamine Stack Blend1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
Glutamine Stack Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glutamine Stack, from the product label.

Tokkyo Nutrition

See all Tokkyo Nutrition products
Name
BTE Wholesalers, LLC
Street Address
587 2nd Street, Suite B
City
Manchester
State
NH
ZipCode
03102
Phone Number
1.866.320.0141
Web Address
www.Tokkyonutrition.com
Pharmacist Counseling Corner

Glutamine Stack by Tokkyo Nutrition: Common Questions

Does Glutamine Stack by Tokkyo Nutrition interact with any medications?
Yes. Based on its ingredients, Glutamine Stack has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glutamine Stack contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glutamine safe if I'm pregnant or breastfeeding?
The data shows L-Glutamine and L-Glutamine Ethyl Ester are likely safe during pregnancy and lactation. We don't hold safety information on the third form. Still, there isn't enough data to be completely certain, so talk with your doctor or pharmacist about what's right for your situation.
What are the most common side effects?
Belching, bloating, constipation, diarrhea, flatulence, and nausea are the most common. At higher doses (10–30 grams daily), these digestive issues show up more often. Dizziness and headache can occur too. Most people tolerate it well.
Can I use this if I have kidney or liver disease?
You should only use it under medical supervision if you have kidney or liver disease. Check with your doctor or pharmacist before starting.
Does it work for muscle recovery?
The evidence we hold covers specific medical conditions—glutamine is rated Effective for sickle cell disease and Possibly Effective for post-surgery recovery and muscle wasting from HIV/AIDS. We don't have data on its use for general fitness or athletic recovery.
I have bipolar disorder. Is this safe for me?
A small number of people with bipolar disorder have reported mania or hypomania while taking glutamine. Because glutamine converts to chemicals that may affect the brain, talk with your doctor or pharmacist before using this product.
What's the difference between the three glutamine forms in this product?
L-Glutamine and L-Glutamine Ethyl Ester are the two forms we have checked. Both convert to the same active amino acid and have the same interaction and safety data. We hold no data on L-Glutamine Alpha Keto Glutarate, so we can't tell you how it compares.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutamine Stack is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutamine Stack label
Go deeper

The Full Monographs Behind Glutamine Stack’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Glutamine Stack's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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