Gold Label Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Gold Label against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Gold Label is a dietary supplement by Active CBD Oil with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 940 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp Oil extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Gold Label by Active CBD Oil
Ask about any prescription or over-the-counter medication and we check it for interactions with Gold Label by Active CBD Oil — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Gold Label by Active CBD Oil
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Active CBD Oil Gold Label is a single-ingredient softgel: hemp oil extract. The capsule shell is the only other component listed.
Hemp oil extract comes from the hemp plant and contains various compounds, including cannabinoids and plant proteins. The product itself is fairly straightforward — one active ingredient per capsule.
Does it work?
Couldn't assess
We don't have strong evidence that hemp oil extract works for the conditions listed on this product's label. The data we hold shows insufficient reliable evidence to rate hemp for constipation, eczema (atopic dermatitis), or familial hypercholesterolemia.
That doesn't mean it doesn't work — it means the evidence isn't established yet in the studies available to us.
How safe is it?
Well-documented data
Hemp seed foods and oils are generally well tolerated at normal food doses. However, concentrated extracts and supplements like this one are less well studied, so caution is advised with larger or supplement-level amounts.
Rare but serious side effects have been reported: allergic reactions ranging from hives to anaphylaxis, facial swelling, shortness of breath, and in one case involving a young child given very high doses of hemp extract, elevated liver enzymes and hepatitis. Allergies to hemp seed do occur, though they're uncommon.
Most people tolerate hemp seed oil without issue, but if you have a known seed allergy or have reacted to hemp before, be careful.
Meds to double-check
Moderate interaction found
If you take estrogen-based hormones (birth control, hormone replacement therapy), blood pressure medications, blood thinners, ACE inhibitors, or any drug your liver metabolizes heavily, double-check this product with your pharmacist or doctor first. The most serious theoretical risk is interference with hormone therapy.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Active CBD Oil Gold Label might appeal to you if you're interested in hemp-based products, but the evidence for its claimed uses isn't solid yet. Because it interacts with a significant number of medications — especially hormones, blood pressure drugs, blood thinners, and drugs your liver processes — you really need to check it against your own prescription list before taking it.
Talk with your doctor or pharmacist about whether it makes sense for you and your health situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Gold Label, straight from the product label.
| Brand | Active CBD Oil |
|---|---|
| Barcode (UPC) | 852947008010 |
| Net contents | 60 Liquid Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Nov 21, 2020 |
| DSLD ID | 239501 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Gold Label by Active CBD Oil, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Hemp Oil extract | 334 mg | -- |
Other ingredients: Active CBD Oil Gold Formula, Capsule Shell
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Scan for 3rd party lab results and more.
Get active, be healthy.
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1 liquid softgel daily or as directed by your health care professional or pharmacist.
Storage
Storage: Keep tightly closed in a cool, dry place in the original container. Do not expose to excessive heat.
Precautions
Keep out of the reach of children.
Caution: Do not use if seal is broken.
As with all dietary supplements, please consult a medical professional before using if you are pregnant, lactating, or have an existing medical condition.
FDA Statement of Identity
Hemp Supplement
Formulation
Maximum bioavailability / Water soluble
Formula
100% decarboxylated / 25mg CBD per capsule
Maximum bioavailability and absorption formula Active CBD Oil utilizes a water soluble formula making it "body ready" for maximum bioavailability and full absorption. Compounds contained within our Active CBD Oil formula may offer benefits via numerous mechanisms of action, including helping to support the body's endocannabinoid system as well as possessing antioxidant activity to help support redox balance within the body. Active CBD Oil formula allows for the transformation of dense poorly soluble hemp oil into a water soluble "body ready" liquid.
FDA Disclaimer Statement
The FDA has not evaluated this product for safety or efficacy.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Gold Label by Active CBD Oil label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Gold Label by Active CBD Oil
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.
Hemp Oil extract
Interacts with940 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Hemp Oil extract monograph & interactionsOther (inactive) ingredients: Active CBD Oil Gold Formula, Capsule Shell. These complete the product’s ingredient list but are not active constituents.
Gold Label by Active CBD Oil Drug Interactions
HelloPharmacist Interaction Report
Active CBD Oil Gold Label, which contains hemp oil extract, does interact with medications.
The most serious interaction is with estrogen-based therapies — hemp theoretically can interfere with how your body handles hormones, and we've seen it normalize estrogen levels in animal studies.
Read the full breakdown — every affected drug type, severity by severity
Hemp may also lower your blood pressure when combined with blood pressure medications (antihypertensive drugs) or ACE inhibitors, raising the theoretical risk of blood pressure dropping too far. It could theoretically increase bleeding risk if you're on blood thinners (anticoagulants) or antiplatelet drugs, though human studies of hemp seed oil at typical doses haven't shown this effect in practice.
Additionally, hemp appears to speed up how your liver processes certain medications through two enzyme pathways — CYP1A2 and CYP3A4 substrates — which may make those drugs less effective. Altogether, these interactions span 939 individual medications.
Before you start this product, check your exact medications with the tool on this page, especially if you take hormones, blood pressure drugs, blood thinners, or any prescription that your liver metabolizes heavily.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Gold Label?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Gold Label interact with 940 drugs. Click any drug to see the details.
1 of the 1 ingredient in Gold Label interact with drugs. Each result below shows which ingredient is responsible. Hemp Oil extract
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Conjugated Estrogens, Methyltestosterone interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Cyproterone Acetate, Ethinyl Estradiol interactionDesogestrel, Ethinyl EstradiolDesogen, Marvelon, Marvelon 21, Marvelon 28, Mircette, Ortho-Cept +2 more
How Desogestrel, Ethinyl Estradiol interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Desogestrel, Ethinyl Estradiol interactionDrospirenone, EstetrolNextstellis
How Drospirenone, Estetrol interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Drospirenone, Estetrol interactionDrospirenone, Ethinyl EstradiolAngeliq, Gianvi, Yasmin
How Drospirenone, Ethinyl Estradiol interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Oil Extract + Drospirenone, Ethinyl Estradiol interactionEsterified EstrogensEstratab, Menest
How Esterified Estrogens interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Esterified Estrogens interactionEsterified Estrogens, MethyltestosteroneEstratest
How Esterified Estrogens, Methyltestosterone interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Esterified Estrogens, Methyltestosterone interactionEstradiolDivigel, Elestrin, Estrace, Estraderm, Estring, Evamist +6 more
How Estradiol interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Estradiol interactionEstradiol, MedroxyprogesteroneDivitren
How Estradiol, Medroxyprogesterone interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Oil Extract + Estradiol, Medroxyprogesterone interactionEstradiol, Norethindrone AcetateActivella
How Estradiol, Norethindrone Acetate interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Estradiol, Norethindrone Acetate interactionEstradiol, NorgestimateOrtho-Prefest
How Estradiol, Norgestimate interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Estradiol, Norgestimate interactionEstradiol, ProgesteroneBijuvanda
How Estradiol, Progesterone interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Oil Extract + Estradiol, Progesterone interactionEstrogenEstrogen
How Estrogen interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Estrogen interactionEstroneOrtho-Est
How Estrone interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Estrone interactionEstropipateOgen, Ortho EST
How Estropipate interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Estropipate interactionEthiny Estradiol, LevonorgestrelLogynon, Microgynon 30 ED
How Ethiny Estradiol, Levonorgestrel interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Ethiny Estradiol, Levonorgestrel interactionEthinyl EstradiolEstinyl
How Ethinyl Estradiol interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Ethinyl Estradiol interactionEthinyl Estradiol, DesogestrelApri, Cesia, Cyclessa, Gedarel, Kariva, Linessa +4 more
How Ethinyl Estradiol, Desogestrel interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Oil Extract + Ethinyl Estradiol, Desogestrel interactionEthinyl Estradiol, DrospirenoneYaz
How Ethinyl Estradiol, Drospirenone interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Ethinyl Estradiol, Drospirenone interactionEthinyl Estradiol, Ethynodiol DiacetateDemulen 1/35, Demulen 1/50, Demulen Compack, Kelnor 1/35, Zovia, Zovia 1/35 +1 more
How Ethinyl Estradiol, Ethynodiol Diacetate interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Ethinyl Estradiol, Ethynodiol Diacetate interactionEthinyl Estradiol, LevonorgestrelAlesse, Alesse 21, Alesse 28, Aviane, Enpresse, Jolessa +18 more
How Ethinyl Estradiol, Levonorgestrel interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Ethinyl Estradiol, Levonorgestrel interactionEthinyl Estradiol, NorethindroneAranelle, Brevicon, Brevicon .5/35 21 day, Brevicon .5/35 28 day, Brevicon 1/35 21 day, Brevicon 1/35 28 day +50 more
How Ethinyl Estradiol, Norethindrone interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Oil Extract + Ethinyl Estradiol, Norethindrone interactionEthinyl Estradiol, Norethindrone, Ferrous FumarateEstrostep Fe, Femcon FE, Junel Fe 1.5/30, Loestrin Fe, Loestrin Fe 1.5/30, Loestrin Fe 1/20 +3 more
How Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interactionEthinyl Estradiol, NorgestimateCilest, Mononessa, Ortho Tri-Cyclen 28, Ortho Tri-Cyclen Lo, Ortho Tri-Cylcen, Ortho-Cyclen +5 more
How Ethinyl Estradiol, Norgestimate interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Oil Extract + Ethinyl Estradiol, Norgestimate interactionEthinyl Estradiol, NorgestrelCryselle, Lo/Ovral, Low-Ogestrel, Ogestrel 0.5/50, Ovral
How Ethinyl Estradiol, Norgestrel interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Oil Extract + Ethinyl Estradiol, Norgestrel interactionEthinyl Estradiol, LevonogestrelLybrel
How Ethinyl Estradiol, Levonogestrel interacts with Gold Label — through 1 ingredient. Tap an ingredient for the detail:
Hemp Oil ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Oil Extract + Ethinyl Estradiol, Levonogestrel interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Gold Label with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hemp Oil extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Gold Label, from the product label.
Active CBD Oil
See all Active CBD Oil products- Name
- DiscoverCBD.com
- Phone Number
- 1-844-462-2366
- Web Address
- www.ActiveCBDOil.com
Gold Label by Active CBD Oil: Common Questions
Does Gold Label by Active CBD Oil interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on birth control or hormone replacement therapy?
Will this lower my blood pressure if I already take a blood pressure medication?
I take a blood thinner — is it safe to use this?
Can I take this while breastfeeding or during pregnancy?
Are there any common side effects?
Does this actually work for constipation or eczema?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Gold Label is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Gold Label’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Gold Label's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC