Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Hempanol-CF Super Strength Ingredients & Drug Interactions

by North American Herb & Spice

Hempanol-CF Super Strength label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hempanol-CF Super Strength against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hempanol-CF Super Strength is a dietary supplement by North American Herb & Spice with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Hempanol-CF Super Strength by North American Herb & Spice

Ask about any prescription or over-the-counter medication and we check it for interactions with Hempanol-CF Super Strength by North American Herb & Spice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Hempanol-CF Super Strength by North American Herb & Spice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 1 of its 2 active ingredients.

This product has 2 active ingredients: a proprietary blend (which we cannot verify) and a raw CO2 extract from high beta caryophyllene and phytoterpene hemp stalk extract. The hemp extract is the ingredient with documented interactions.

The capsule itself is made from BSE-free beef gelatin, an inactive ingredient that holds everything together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Hemp's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: calm focus and nervous system support.
  • We looked for evidence on: Psychological well-being, anxiety, stress, mood.
  • The closest evidence on file: Hemp is rated "Insufficient Reliable Evidence To Rate" for Psychological well-being (Natural Medicines).

The evidence we hold doesn't establish that hemp extract works for the conditions listed—constipation, eczema (atopic dermatitis), and familial high cholesterol all rate insufficient reliable evidence to make a claim either way. If you're considering this product for one of those reasons, that's a gap worth discussing with your doctor or pharmacist.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods in normal amounts are generally well tolerated, but this is a concentrated extract and supplement, which are far less studied. Serious side effects are rare but have been reported—anaphylaxis, allergic reactions (hives, facial swelling, breathing trouble), and in one case report, liver enzyme elevation and hepatitis in a young child given very high doses.

Allergy to hemp seed is uncommon but documented. Because concentrated extracts carry more uncertainty than food amounts, caution is warranted, especially if you have a history of allergies.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take estrogen or hormone therapy (Moderate interaction). Also flag any blood pressure medications, blood thinners, ACE inhibitors, or drugs metabolized by your liver—these all have Minor interactions documented.

No interactions are documented for the proprietary blend because we hold no data for it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This hemp extract product interacts with hormone therapy (the biggest concern), blood pressure medications, blood thinners, and certain drugs your liver processes. If you take any of those, check with your doctor or pharmacist before starting.

The evidence for what this product actually does isn't established in our data. Concentrated hemp extracts are less studied than hemp seed foods, so safety data is limited.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hempanol-CF Super Strength, straight from the product label.

Brand North American Herb & Spice
Barcode (UPC) 635824007296
Net contents 120 Gelcap(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 269414
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hempanol-CF Super Strength by North American Herb & Spice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
40
UPC/BARCODE
635824007296
IngredientAmount% DV
Proprietary Blend420 mg--
raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract0 NP--

Other ingredients: BSE-free Beef Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take 3 capsules for daily immune support with meals or juice or on an empty stomach.

Formula

Hempanol-CF Super Strength, powered by CO2-extracted cannabis extract, supports a healthy nervous system and more by activating the body's CB2 receptor system. Stay calm and focused with this potent formula. Naturally rich in cannabinoids and phytoterpenes, Hempanol-CF Super Strength is the ideal hemp-cannabis extract for daily use.

Whole food hemp 3000 mg hemp extract per bottle

18% hemp phytoterpenes

Formulation

Unlike other hemp products, it’s free of all solvents and is never heat-treated, which is why it is the most potent of all.

Raw Calm, focus, & nerve support

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hempanol-CF Super Strength by North American Herb & Spice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hempanol-CF Super Strength label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hempanol-CF Super Strength by North American Herb & Spice

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

420 mg per serving Form: organic cold-pressed Hemp seed Oil, organic extra virgin Olive Oil

Raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract

Interacts with
938 drugs
0 NP per serving

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract monograph & interactions

Other (inactive) ingredients: BSE-free Beef Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hempanol-CF Super Strength by North American Herb & Spice Drug Interactions

Want to check YOUR meds against Hempanol-CF Super Strength?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract 938

Individual Drug Interactions

The ingredients in Hempanol-CF Super Strength interact with 938 drugs. Click any drug to see the details.

1 of the 2 ingredients in Hempanol-CF Super Strength interact with drugs. Each result below shows which ingredient is responsible. raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Hempanol-CF Super Strength with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hempanol-CF Super Strength, from the product label.

North American Herb & Spice

See all North American Herb & Spice products
Name
North American Herb & Spice
Street Address
13900 W. Polo Trail Drive
City
Lake Forest
State
IL
ZipCode
60045
Phone Number
1-800-243-5242
Web Address
www.oreganol.com
Pharmacist Counseling Corner

Hempanol-CF Super Strength by North American Herb & Spice: Common Questions

Does Hempanol-CF Super Strength by North American Herb & Spice interact with any medications?
Yes. Based on its ingredients, Hempanol-CF Super Strength has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hempanol-CF Super Strength contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on hormone therapy or birth control?
Not without checking first. The hemp extract in this product may interfere with how your body responds to estrogens, and it's rated a Moderate concern. Talk with your doctor or pharmacist—they know your full picture and can advise whether it's okay for you.
What if I take blood pressure or blood thinner medication?
These are Minor interactions, but real. Hemp may add to the blood-pressure-lowering effect of your meds (risking a dangerous drop) or increase bleeding risk with blood thinners. Check with your doctor or pharmacist before adding this to your routine.
Does this actually work for eczema, high cholesterol, or constipation?
The evidence we hold doesn't establish that it works for any of those—all three rate insufficient reliable evidence. That doesn't mean it doesn't; it means the research isn't there yet. If one of those is why you're interested, it's worth a conversation with your doctor about whether there's a better option.
Is this safe if I've never had an allergic reaction to hemp?
Allergies to hemp seed are uncommon, but they do happen—and some people had a reaction on first exposure. Because this is a concentrated extract (not a food amount), and concentrated extracts are less studied overall, there's more uncertainty. If you have a history of food or plant allergies, mention it to your pharmacist first.
What's in the capsule itself?
The active ingredients are the hemp extract and a proprietary blend. The capsule shell is made from BSE-free beef gelatin—that's it. If you avoid gelatin (for dietary or religious reasons), this one's not for you.
How much hemp extract is in each dose?
That information isn't on file for us from the product label. Check the bottle or the manufacturer's website for the exact amount per capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hempanol-CF Super Strength is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hempanol-CF Super Strength label
Go deeper

The Full Monographs Behind Hempanol-CF Super Strength’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hemp

Interacts with 938 drugs

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...

Read the full Hemp monograph →
Sources

Sources & How We Checked

Hempanol-CF Super Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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