Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Holy Basil Force Ingredients & Drug Interactions

by New Chapter

Holy Basil Force label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Holy Basil Force against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Holy Basil Force is a dietary supplement by New Chapter with 2 active ingredients. Its ingredients are commonly taken for stress and anxiety, blood sugar support, respiratory complaints.Based on those ingredients, 212 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Holy Basil (Ocimum sanctum) (leaf) hydroethanolic extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Holy Basil Force by New Chapter

Ask about any prescription or over-the-counter medication and we check it for interactions with Holy Basil Force by New Chapter — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Holy Basil Force by New Chapter

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Holy Basil Force contains 2 active ingredients: holy basil leaf in two forms—a hydroethanolic extract and a supercritical extract—both from the plant Ocimum sanctum. The product also includes several inactive ingredients for the capsule and formulation: olive oil, hypromellose, beeswax, maltodextrin, and candelilla wax.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Holy Basil's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune function and cognitive alertness support.
  • We looked for evidence on: Stress, Generalized anxiety disorder (GAD), Respiratory tract infections.
  • The closest evidence on file: Holy Basil is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD) (Natural Medicines).
  • Also on file: Holy Basil is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections, Stress.

The evidence we hold doesn't establish how well holy basil works for any of its proposed uses—generalized anxiety, asthma, headache, respiratory tract infections, dental plaque, or diabetes all carry a rating of insufficient reliable evidence. That doesn't mean it doesn't work; it means the quality and amount of research available to us aren't strong enough to say either way.

If you're considering this for a specific condition, talk with your doctor or pharmacist about what the current science suggests for your situation.

The evidence, ingredient by ingredient Holy Basil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Holy basil extract is generally well tolerated in the short term, but long-term safety data in humans are limited. The most common side effects are loose stools and nausea—a small number of trial participants experienced these with capsules.

Because animal data raise concerns and human safety isn't established, the safety data advise against use during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Holy Basil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Holy Basil Force, double-check with your doctor or pharmacist if you take blood thinners (anticoagulants or antiplatelet drugs), diabetes medications, or pentobarbital (Nembutal)—all are affected by Moderate-severity interactions with the holy basil in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Holy Basil Force is a two-ingredient product built entirely from holy basil in different extract forms. It's generally well tolerated short-term, but the evidence for how well it works is insufficient—and it interacts with blood thinners, diabetes drugs, and the barbiturate pentobarbital.

If you take any of these medications, check with your doctor or pharmacist before starting. Pregnancy and breastfeeding are times to avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Holy Basil Force, straight from the product label.

Brand New Chapter
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2018
DSLD ID 82756
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Holy Basil Force by New Chapter, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Holy Basil (Ocimum sanctum) (leaf) hydroethanolic extract268 mg--
Holy Basil (Ocimum sanctum) (leaf) supercritical extract268 mg--

Other ingredients: organic Olive Oil, extra-virgin Olive Oil, Hypromellose, organic yellow Beeswax, Maltodextrin, Candelilla Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Discover the force of the whole

New Chapter delivers the wisdom of whole food.

2016 New Chapter, Inc.

General Statements

Holy basil, also known as tulsi, supports immune cells and multiple markers of healthy immune function. Holy basil promotes cognitive functions that support your alertness, focus, and healthy attention span including speed of memory and short-term memory.

Full-Spectrum Extraction: Our Difference Many companies isolate elements from an herb, concentrate them, and label it “whole herb.”

Using only natural supercritical CO2 or traditional techniques of extraction, our force extracts guarantee the fullest spectrum of beneficial phytonutrients in their natural profile.

The New Chapter Money-Back Guarantee: We proudly stand behind every product we make. However, if you are not satisfied, please visit www.newchapter.com/guarantee for refund details.

Please recycle this bottle after use.

Made in the USA

Formula

We use a whole-food approach to deliver a broad spectrum of holy basil's beneficial compounds, matching nature's true profile by extracting the whole leaf using both supercritical and traditional methods.

Holy basil supports healthy immune function & helps with focus and alertness

Formulation

Our full-spectrum process preserves precious plant compounds, delivered in a 100% vegetarian formulation from extract to capsule.

Non-GMO verified formula

100% Vegetarian

Gluten free; 100% Vegetarian; No artificial flavors or colors.

Gluten free; 100% Vegetarian; No artificial flavors or colors.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Non GMO Project Verified

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: One capsule daily with food.

Precautions

Not recommended for use in children.

Caution: As with any dietary supplement, you should advise your healthcare professional of the use of this product.

If you are nursing, pregnant, or considering pregnancy, you should consult your healthcare professional prior to using this product.

Discontinue use and contact your healthcare professional if you experience a side effect or an allergic reaction. Do not exceed suggested use.

Discontinue use and contact your healthcare professional if you experience a side effect or an allergic reaction.

Keep out of reach of children.

General

6085-A02

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Holy Basil Force by New Chapter label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Holy Basil Force label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Holy Basil Force by New Chapter

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Holy Basil (Ocimum sanctum) (leaf) hydroethanolic extract

Interacts with
212 drugs
268 mg per serving

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and p...

Holy Basil (Ocimum sanctum) (leaf) hydroethanolic extract monograph & interactions

Holy Basil (Ocimum sanctum) (leaf) supercritical extract

Interacts with
212 drugs
268 mg per serving

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and p...

Holy Basil (Ocimum sanctum) (leaf) supercritical extract monograph & interactions

Other (inactive) ingredients: Organic Olive Oil, Extra-virgin Olive Oil, Hypromellose, Organic yellow Beeswax, Maltodextrin, Candelilla Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Holy Basil Force by New Chapter Drug Interactions

Want to check YOUR meds against Holy Basil Force?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
212Drugs
212 Moderate

Ingredients driving the most interactions

Holy Basil (Ocimum sanctum) (leaf) hydroethanolic extract 212

Individual Drug Interactions

The ingredients in Holy Basil Force interact with 212 drugs. Click any drug to see the details.

1 of the 2 ingredients in Holy Basil Force interact with drugs. Each result below shows which ingredient is responsible. Holy Basil (Ocimum sanctum) (leaf) hydroethanolic extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Holy Basil Force with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Holy Basil (Ocimum sanctum) (leaf) hydroethanolic extract3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
Holy Basil (Ocimum sanctum) (leaf) hydroethanolic extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Holy Basil Force, from the product label.

New Chapter

See all New Chapter products
Name
New Chapter, Inc.
Street Address
90 Technology Drive
City
Brattleboro
State
VT
ZipCode
05301
Phone Number
888-874-4461
Web Address
www.newchapter.com/guarantee
Pharmacist Counseling Corner

Holy Basil Force by New Chapter: Common Questions

Does Holy Basil Force by New Chapter interact with any medications?
Yes. Based on its ingredients, Holy Basil Force has a known interaction with 212 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Holy Basil Force contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advise against it. Animal research raises concerns and human safety isn't established, so avoid Holy Basil Force during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether another option makes sense for you.
What are the side effects?
Loose stools and nausea are the most common, though only a small number of people taking holy basil capsules in trials experienced them. The product is generally well tolerated short-term, but long-term safety data in humans are limited.
Does this really work for anxiety, diabetes, or other conditions?
The evidence we hold doesn't establish how well it works for any of its marketed uses—generalized anxiety, asthma, headache, respiratory infections, dental plaque, or diabetes all have insufficient reliable evidence. You'd want to discuss with your doctor what research supports its use for your specific concern.
Why are there two holy basil extracts in one product?
Both active ingredients are holy basil leaf, but extracted using two different methods: hydroethanolic and supercritical. Both forms appear in the product, though they carry the same interaction risks and the same level of unproven effectiveness.
Does this product contain any fillers?
Yes. Besides the two active holy basil extracts, the product contains inactive ingredients including olive oil, beeswax, hypromellose, maltodextrin, and candelilla wax for the capsule and formulation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Holy Basil Force is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Holy Basil Force label
Go deeper

The Full Monographs Behind Holy Basil Force’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph →
Sources

Sources & How We Checked

Holy Basil Force's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
  6. Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
  7. Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
  8. Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.

See these in context on the Holy Basil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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