Iron Response By Innate Response Formulas Overview & Drug Interactions

Folate and folic acid are forms of vitamin B9, essential for health. Folate occurs naturally in foods like leafy vegetables, legumes, and fruits, while folic acid is the synthetic form used in supplements and fortified foods. Since 1998, the US has fortified cereals, baking flour, pasta, and bakery items with folic acid to prevent deficiencies. Naturally occurring folate, or pteroylpolyglutamate, has lower bioavailability (40% to 50%) compared to nearly 100% for synthetic folic acid. Foods rich in folate include asparagus, mushrooms, yeast, legumes, spinach, broccoli, lettuce, bananas, melons, oranges, tomatoes, lemons, and animal products like beef liver and kidney. Some supplements contain L-5-methyltetrahydrofolate (L-5-MTHF), a reduced folate form. L-5-MTHF, dependent on vitamin B12 for metabolism, is absorbed faster and more effectively than folic acid, especially in individuals with specific MTHFR genotypes. Studies show that women taking L-5-MTHF had slightly higher red blood cell folate concentrations compared to those taking folic acid, although long-term use results in similar blood levels and effectiveness for preventing neural tube defects.

Vitamin B12, also known as cobalamin, is a water-soluble vitamin crucial for several bodily functions. It plays a pivotal role in the formation of red blood cells, aiding in the prevention of anemia. Vitamin B12 is essential for maintaining a healthy nervous system and proper brain function, as it is involved in the synthesis of myelin, the protective sheath around nerve fibers. This vitamin is primarily found in animal-based foods such as meat, fish, dairy products, and eggs, making it important for vegetarians and vegans to consider supplementation. A deficiency in vitamin B12 can lead to neurological issues, fatigue, and cognitive impairment.

Beetroot is a type of root vegetable belonging to the Chenopodiaceae family. It is commonly consumed as a food and utilized as a dietary supplement. Beetroot supplements are purported to have a number of potential health benefits, including lowering blood pressure by increasing the production of nitric oxide, improving exercise performance, and reducing inflammation. Dietary supplements containing beetroot are generally in powdered form, and are sometimes standardized by their nitrate content.