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Dietary supplement

Memory Maintenance Ingredients & Drug Interactions

by Vitamer Laboratories

Memory Maintenance label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Memory Maintenance against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Memory Maintenance is a dietary supplement by Vitamer Laboratories with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 307 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sunflower Phosphatidylserine Complex, organic Blueberry powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Memory Maintenance by Vitamer Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Memory Maintenance by Vitamer Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Memory Maintenance by Vitamer Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients. Blueberry powder is a concentrated form of the whole fruit, traditionally used for eye and brain health.

Sunflower phosphatidylserine is a naturally occurring compound found in cell membranes — it's often extracted from plant sources and studied for cognitive support. The capsule itself is made from vegetable material, with inactive ingredients including dicalcium phosphate, cellulose, magnesium stearate, and silica to hold everything together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Memory and brain health support.
  • We looked for evidence on: Age-related cognitive decline, Cognitive function, Dementia, Alzheimer disease, Memory, Neural function — and 1 related terms.
  • The strongest evidence on file: Phosphatidylserine is rated "Possibly Effective" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Phosphatidylserine is rated "Possibly Effective" for Alzheimer disease.
  • Also on file: Phosphatidylserine is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Dementia.

Phosphatidylserine is possibly effective for age-related cognitive decline and Alzheimer disease according to the evidence we hold. For blueberry, the data on cognitive decline is insufficient to rate — we don't have strong enough evidence either way.

Neither ingredient has established effectiveness for anxiety, athletic performance, or heart health, though both have been studied for some of these uses.

The evidence, ingredient by ingredient Blueberry Phosphatidylserine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberry is generally well tolerated as a food and is rated likely safe in pregnancy and lactation. However, concentrated blueberry supplements haven't been well studied in pregnancy or high-dose extracts while breastfeeding — the safety data advises caution.

Freeze-dried blueberries can cause constipation, diarrhea, nausea, or vomiting; one trial found that over a quarter of participants stopped taking high-dose freeze-dried blueberries in the first week due to stomach upset. Phosphatidylserine is generally well tolerated, though long-term safety isn't fully established.

It can cause flatulence, stomach upset, headache, insomnia (especially at higher doses around 600 mg), and nausea — gastrointestinal side effects are more likely at doses of 200–300 mg per day. The safety data advises against use during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Blueberry Phosphatidylserine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Phosphatidylserine, Blueberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 307 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this product, double-check these medication types: anticholinergic drugs and cholinergic drugs (Moderate interactions with phosphatidylserine), then antidiabetes medications, flurbiprofen, and buspirone (Minor interactions with blueberry). Your pharmacist can run your exact medications through the checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Memory Maintenance is worth considering if you're looking to support cognitive function — phosphatidylserine has decent evidence for age-related memory concerns. Talk with your pharmacist or doctor before starting if you take medications for bladder control, Parkinson's disease, myasthenia gravis, Alzheimer's disease, blood sugar management, or pain relief.

If you have a sensitive stomach, start low and watch for nausea or digestive upset.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Memory Maintenance, straight from the product label.

Brand Vitamer Laboratories
Barcode (UPC) 719985457258
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Dec 23, 2016
DSLD ID 68754
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Memory Maintenance by Vitamer Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
719985457258
IngredientAmount% DV
organic Blueberry powder20 mg--
Sunflower Phosphatidylserine Complex167 mg--

Other ingredients: Vegetable Capsule, Dicalcium Phosphate, Cellulose, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

We guarantee our supplements for potency and purity

Human brain cell membranes are highly enriched with phosphatidylserine (PS). PS levels in these tissues ensure the membrane's fluidity and structure, thus their function. Nerve cells, in particular, depend on healthy membrane function for normal neurotransmitter metabolism and nerve signal transmission. Maintaining brain PS levels can be associated with normal and efficient signalling processes, efficient brain glucose consumption, and other biological pathways that are crucial to ensure normal and healthy cognitive and mental functions.

Supports brain health

Suggested/Recommended/Usage/Directions

Contains no artificial colors, flavors or preservatives; no wheat, gluten, milk, eggs, peanuts, tree nuts, soy, crustacean shellfish or fish.

Suggested Use: Take one capsule daily with or without food.

Formulation

Suitable for vegans.

Soy free

Formula

Our Memory Maintenance is a daily source of PS, as well as polyphenols from organic blueberry, which have been studied for their roles in brain health.

Made from non-GMO sunflowers and blueberries

Brand IP Statement(s)

Sharp-PS GREEN

Sharp-PS GREEN is a soy-free Phosphatidylserine

Sharp-PS is a registered trademark of Enzymotec Ltd.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Double Verified Gluten Free

Precautions

Keep out of reach of children.

General

VVL 457-30A

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Memory Maintenance by Vitamer Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Memory Maintenance label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Memory Maintenance by Vitamer Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic Blueberry powder

Interacts with
88 drugs
20 mg per serving

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...

Organic Blueberry powder monograph & interactions

Sunflower Phosphatidylserine Complex

Interacts with
219 drugs
167 mg per serving Form: Phosphatidylserine

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...

Sunflower Phosphatidylserine Complex monograph & interactions

Other (inactive) ingredients: Vegetable Capsule, Dicalcium Phosphate, Cellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Memory Maintenance by Vitamer Laboratories Drug Interactions

Want to check YOUR meds against Memory Maintenance?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
307Drugs
219 Moderate 88 Minor

Ingredients driving the most interactions

Sunflower Phosphatidylserine Complex 219
organic Blueberry powder 88

Individual Drug Interactions

The ingredients in Memory Maintenance interact with 307 drugs. Click any drug to see the details.

2 of the 2 ingredients in Memory Maintenance interact with drugs. Each result below shows which ingredient is responsible. Sunflower Phosphatidylserine Complex organic Blueberry powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Memory Maintenance with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sunflower Phosphatidylserine Complex2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.

Likelihood Possible Evidence B
Cholinergic Drugs

Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence B
Sunflower Phosphatidylserine Complex full monograph & interactions

organic Blueberry powder3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
organic Blueberry powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Memory Maintenance, from the product label.

Vitamer Laboratories

See all Vitamer Laboratories products
Phone Number
1-888-710-0006
Pharmacist Counseling Corner

Memory Maintenance by Vitamer Laboratories: Common Questions

Does Memory Maintenance by Vitamer Laboratories interact with any medications?
Yes. Based on its ingredients, Memory Maintenance has a known interaction with 307 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Memory Maintenance contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Blueberry is rated likely safe in pregnancy and lactation, but the concentrated supplements haven't been well studied — talk with your doctor about whether this product makes sense for you. Phosphatidylserine is a different story: the safety data advises against it during pregnancy and breastfeeding. It's best to skip this product if you're pregnant or nursing, or get personalized advice from your pharmacist.
Is blueberry actually in this product?
Yes — it's listed as organic blueberry powder, one of the two active ingredients. The other is sunflower phosphatidylserine, a compound from plant cell membranes.
Will this help my memory?
Phosphatidylserine is possibly effective for age-related memory loss and Alzheimer disease based on the evidence we hold. For blueberry and general brain fog, the data isn't strong enough to say — we have insufficient evidence to rate either way.
What side effects should I watch for?
Blueberry can cause constipation, diarrhea, nausea, or vomiting — particularly if you're taking a high-dose freeze-dried form. Phosphatidylserine may cause stomach upset, flatulence, headache, insomnia (worse at higher doses), or nausea. Both are generally well tolerated, but start low if you have a sensitive stomach.
Why is there a warning about anticholinergic drugs?
Phosphatidylserine in this product increases acetylcholine levels in your body, which can interfere with how anticholinergic medications work — drugs like benztropine or oxybutynin. That's why you need to check your exact medications with your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Memory Maintenance label
Go deeper

The Full Monographs Behind Memory Maintenance’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blueberry

Interacts with 88 drugs

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...

Read the full Blueberry monograph → Herb & supplement monograph

Phosphatidylserine

Interacts with 219 drugs

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...

Read the full Phosphatidylserine monograph →
Sources

Sources & How We Checked

Memory Maintenance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Phosphatidylserine 9 references
  1. Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
  2. Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
  3. Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
  4. Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
  5. Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
  6. Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
  7. Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
  8. Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
  9. Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed

See these in context on the Phosphatidylserine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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