Major interaction on record — check this product against your medications before combining. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

NZ-CoQ10 200 mg Ingredients & Drug Interactions

by Everyday Health

NZ-CoQ10 200 mg label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking NZ-CoQ10 200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

NZ-CoQ10 200 mg is a dietary supplement by Everyday Health with 4 active ingredients. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 418 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Policosanol, Coenzyme Q-10, Hawthorn Flower, Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against NZ-CoQ10 200 mg by Everyday Health

Ask about any prescription or over-the-counter medication and we check it for interactions with NZ-CoQ10 200 mg by Everyday Health — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of NZ-CoQ10 200 mg by Everyday Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 4 active ingredients. Coenzyme Q10 (200 mg per capsule) is an antioxidant your body naturally makes and uses for energy in your cells.

Policosanol is a plant-derived compound studied for cardiovascular effects. Hawthorn flower, leaf extract and hawthorn berry extract are botanical preparations from the hawthorn plant, traditionally used in heart health support.

The capsules also contain gelatin and rice flour as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support cardiovascular health.
  • We looked for evidence on: Angina, Arrhythmia, Atherosclerosis, Cardiovascular disease (CVD), Congestive heart failure (CHF), Coronary heart disease (CHD) — and 4 related terms.
  • The strongest evidence on file: Coenzyme Q10 is rated "Possibly Effective" for Congestive heart failure (CHF) (Natural Medicines).
  • Also on file: Policosanol is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD), Familial hypercholesterolemia, Hypertension.
  • Also on file: Hawthorn is rated "Insufficient Reliable Evidence To Rate" for Angina, Arrhythmia, Atherosclerosis.

Coenzyme Q10 is rated likely effective for CoQ10 deficiency and possibly effective for fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy. Policosanol is rated likely effective for intermittent claudication (leg pain with walking) but the evidence is insufficient to rate it for coronary heart disease or familial hypercholesterolemia.

For hawthorn, the data we hold shows insufficient evidence to rate it for angina, anxiety, arrhythmia, atherosclerosis, cardiovascular disease, or cognitive function — so we can't say whether it works for those purposes based on what we have on file.

The evidence, ingredient by ingredient Coenzyme Q10 Policosanol Hawthorn

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coenzyme Q10 is generally well tolerated by most adults. In clinical studies, no serious side effects were reported.

The most common mild effects — gastrointestinal discomfort, nausea, diarrhea, heartburn — occur in less than 1% of people and can often be reduced by splitting doses above 100 mg. A small number of people have reported headache, dizziness, insomnia, or skin itching.

There is not enough reliable safety data on coenzyme Q10 in pregnancy, so it's best to avoid it unless your doctor advises otherwise. Safety while breastfeeding hasn't been well studied — use caution and check with your doctor.

Policosanol is usually well tolerated. Uncommon mild side effects include headache, dizziness, insomnia, stomach upset, and skin rash.

There is not enough safety information to use policosanol during pregnancy or while breastfeeding — the safety data advises against both. Hawthorn is generally well tolerated in studies, but because it affects the heart, it needs medical supervision if you have a heart condition.

Serious side effects are rare but have included acute kidney failure from an allergic reaction. There isn't enough safety information for hawthorn in pregnancy or breastfeeding — avoid use unless your doctor advises otherwise.

Side effects, ingredient by ingredient Coenzyme Q10 Policosanol Hawthorn

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Policosanol, Hawthorn, Coenzyme Q10.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications.
  • For scale: 418 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take: nitrates or sildenafil and similar drugs (risk of dangerous low blood pressure — Major severity); warfarin or other blood thinners and antiplatelet agents (risk of increased bleeding — Moderate); beta-blockers, calcium channel blockers, or other blood pressure medications (risk of blood pressure dropping too low — Moderate); digoxin for heart rhythm (risk of digoxin effects becoming too strong — Moderate); chemotherapy drugs like cyclophosphamide (risk of reduced drug effectiveness — Moderate); or diabetes medications (risk of blood sugar dropping too low — Moderate).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This combination might work for you if you're interested in CoQ10 for deficiency, fibromyalgia, or migraine, and hawthorn for general cardiovascular support — but hawthorn's effectiveness for most heart conditions isn't established in our data. If you take any blood pressure medications, blood thinners, heart drugs, or diabetes medications, you need to check with your own doctor or pharmacist before starting, because the interactions are real and could change how your medications work.

Same goes for anyone on nitrates or erectile dysfunction drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NZ-CoQ10 200 mg, straight from the product label.

Brand Everyday Health
Barcode (UPC) 9421905900089
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 306073
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NZ-CoQ10 200 mg by Everyday Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
9421905900089
IngredientAmount% DV
Coenzyme Q-10200 mg--
Policosanol20 mg--
Hawthorn Flower, Leaf Extract100 mg--
Hawthorn Berry Extract100 mg--

Other ingredients: Gelatin, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

NZ-CoQ10 200mg is a powerful combination of Coenzyme Q10, Hawthorn extract and Policosanol to support cardiovascular health.

Policosanol (from sugar cane wax) Hawthorn extract (fruit, leaf and flowers)

FDA Statement of Identity

Dietary Supplement

Formulation

Heart & cholesterol New Zealand Premium Quality Made in New Zealand from premium imported ingredients

Manufactured under GMP Satisfaction guaranteed

Suggested/Recommended/Usage/Directions

Only one per day!

Directions Take 1 capsule daily, with meals, or as directed by your healthcare professional.

Precautions

Caution Keep out of reach of children.

Contact healthcare professionals immediately if you have any side effects. Do not use if outer seal or seal under cap is broken or missing.

Storage

Keep tightly closed in a cool dry place.

General Statements

www.nzcoq10.nz

100% Satisfaction guaranteed

Seals/Symbols

GMP Certified Good Manufacturing Practice

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

NZ-CoQ10 200 mg by Everyday Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

NZ-CoQ10 200 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in NZ-CoQ10 200 mg by Everyday Health

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Coenzyme Q-10

Interacts with
198 drugs
200 mg per serving Form: Ubiquinone

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q-10 monograph & interactions

Policosanol

Interacts with
242 drugs
20 mg per serving Form: Sugar Cane Wax

Policosanol is a mix of waxy alcohols (mostly octacosanol) made from sugar cane or other plant waxes, and it is often marketed as a natural way to low...

Policosanol monograph & interactions

Hawthorn Flower, Leaf Extract

Interacts with
191 drugs
100 mg per serving Form: Crataegus oxyacantha Flower Extract, Crataegus oxyacantha Leaf Extract

Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when...

Hawthorn Flower, Leaf Extract monograph & interactions

Hawthorn Berry Extract

Interacts with
191 drugs
100 mg per serving Form: Crataegus oxyacantha Fruit Extract

Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when...

Hawthorn Berry Extract monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

NZ-CoQ10 200 mg by Everyday Health Drug Interactions

Want to check YOUR meds against NZ-CoQ10 200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
418Drugs
14 Major 289 Moderate 115 Minor

Ingredients driving the most interactions

Policosanol 242
Coenzyme Q-10 198
Hawthorn Flower, Leaf Extract 191

Individual Drug Interactions

The ingredients in NZ-CoQ10 200 mg interact with 418 drugs. Click any drug to see the details.

3 of the 4 ingredients in NZ-CoQ10 200 mg interact with drugs. Each result below shows which ingredient is responsible. Policosanol Coenzyme Q-10 Hawthorn Flower, Leaf Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in NZ-CoQ10 200 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Policosanol6 drug types · 242 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking policosanol with other antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Some clinical research shows that taking policosanol 10-50 mg daily for 7-15 days can inhibit platelet aggregation in healthy patients. Although, one clinical trial shows that taking policosanol 10 mg twice daily for 2 weeks prior to warfarin dosing does not affect warfarin pharmacokinetics or warfarin response. Furthermore, a study in patients undergoing percutaneous coronary intervention with a drug-eluting stent found that taking policosanol 40 mg plus clopidogrel and aspirin daily for 30 days modestly reduced the risk for minor bleeding events when compared with taking clopidogrel and aspirin alone. Until more is known, use with caution.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, policosanol might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Clinical research shows that policosanol can lower blood glucose levels.

Likelihood Possible Evidence B
Beta-Blockers

Concomitant use of policosanol with beta-blockers can cause additive blood pressure-lowering effects.
Clinical research shows that policosanol 5 mg daily can have additive blood pressure-lowering effects in patients with hypertension who are taking beta-blockers. Also, animal research shows that policosanol can increase the blood-pressure lowering effects of propranolol.

Likelihood Probable Evidence A
Nitroprusside (Nitropress)

Theoretically, concomitant use of policosanol with nitroprusside might cause additive blood pressure-lowering effects.
Animal research shows that taking policosanol along with nitroprusside can increase the blood pressure-lowering effects of nitroprusside.

Likelihood Possible Evidence D
Propranolol (Inderal)

Animal research shows that taking policosanol along with propranolol can increase the blood pressure-lowering effects of propranolol.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, taking policosanol with warfarin might increase the risk of bruising and bleeding.
Some clinical research shows that taking policosanol 10-50 mg daily for 7-15 days can inhibit platelet aggregation in healthy patients. However, one clinical trial shows that taking policosanol 10 mg twice daily for 2 weeks prior to warfarin dosing does not affect warfarin pharmacokinetics or warfarin response.

Likelihood Possible Evidence B
Policosanol full monograph & interactions

Coenzyme Q-103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q-10 full monograph & interactions

Hawthorn Flower, Leaf Extract6 drug types · 191 drugs

Nitrates

Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.

Likelihood Probable Evidence D
Phosphodiesterase-5 Inhibitors

Theoretically, concomitant use might result in additive vasodilation and hypotension.
Hawthorn might inhibit PDE-5 and cause vasodilation.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that hawthorn can inhibit platelet aggregation. However, its effect in humans is unclear. One observational study shows that patients taking hawthorn shortly before undergoing coronary artery bypass graft (CABG) surgery or valve replacement surgery have a 10% incidence of postoperative bleeding, compared with 1% in those who never consumed hawthorn extract. However, clinical research shows that taking a specific preparation of dried hawthorn leaves and flowers (Crataesor, Soria Natural Lab) 800 mg three times daily for 15 days does not affect platelet aggregation or levels of thromboxane B2, the metabolite of thromboxane A2, in healthy humans.

Likelihood Possible Evidence D
Beta-Blockers

Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Some evidence shows that hawthorn might lower blood pressure and heart rate.

Likelihood Possible Evidence D
Calcium Channel Blockers

Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, hawthorn might potentiate the effects and adverse effects of digoxin.
Hawthorn appears to improve cardiac output; however, hawthorn does not appear to affect digoxin pharmacokinetics. Case reports suggest that at least one species of hawthorn root extract (Crataegus mexicana) may produce adverse effects similar to digoxin and can cross-react with digoxin assays, leading to falsely elevated plasma digoxin levels.

Likelihood Possible Evidence D
Hawthorn Flower, Leaf Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for NZ-CoQ10 200 mg, from the product label.

Everyday Health

See all Everyday Health products
Name
Everyday Health Ltd.
Street Address
3, 1 Kingsford Smith Drive
City
Rangiora
ZipCode
7400
Web Address
www.everydayhealth.nz
Pharmacist Counseling Corner

NZ-CoQ10 200 mg by Everyday Health: Common Questions

Does NZ-CoQ10 200 mg by Everyday Health interact with any medications?
Yes. Based on its ingredients, NZ-CoQ10 200 mg has a known interaction with 418 medications, including 14 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
NZ-CoQ10 200 mg contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's coenzyme Q10 and what does it do?
Coenzyme Q10 is a naturally occurring compound your body uses to produce energy inside your cells. This supplement is rated likely effective if you have a documented CoQ10 deficiency and possibly effective for fibromyalgia, migraine, heart failure, and nerve pain from diabetes.
Can I take this if I'm pregnant?
There isn't enough reliable safety data for coenzyme Q10 in pregnancy, so it's best to avoid it unless your doctor advises otherwise. Hawthorn and policosanol should also be avoided in pregnancy due to insufficient safety information. Talk with your doctor about whether this product is right for you.
Can I take this while breastfeeding?
Safety data for breastfeeding is limited for all three ingredients. Hawthorn and policosanol should be avoided while breastfeeding. For coenzyme Q10, the safety hasn't been well studied, so use caution and check with your doctor before starting.
What side effects might I experience?
Most people tolerate this product well. The most common side effects are mild gastrointestinal issues like nausea, diarrhea, or heartburn (less than 1% of people). A few people have reported headache, dizziness, insomnia, or skin rash. Serious side effects are rare but have included allergic reactions.
Will this help my heart?
Coenzyme Q10 is possibly effective for congestive heart failure. Policosanol is likely effective for leg pain caused by poor circulation (intermittent claudication), but the evidence doesn't support rating it for coronary heart disease. For hawthorn, we don't have enough data to say whether it works for heart conditions.
Why do I need to check my medications with your tool?
This product interacts with over 400 medications across many categories — blood thinners, blood pressure drugs, heart medications, diabetes drugs, and chemotherapy. Even though you may not experience a problem, your doctor or pharmacist needs to see your specific prescriptions to make sure this supplement won't interfere with how they work.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if NZ-CoQ10 200 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NZ-CoQ10 200 mg label
Go deeper

The Full Monographs Behind NZ-CoQ10 200 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph → Herb & supplement monograph

Policosanol

Interacts with 242 drugs

Policosanol is a mix of waxy alcohols (mostly octacosanol) made from sugar cane or other plant waxes, and it is often marketed as a natural way to lower cholesterol. Early studies from Cuba...

Read the full Policosanol monograph → Herb & supplement monograph

Hawthorn

Interacts with 191 drugs

Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when added to standard care. However, the ev...

Read the full Hawthorn monograph →
Sources

Sources & How We Checked

NZ-CoQ10 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 80 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coenzyme Q10 40 references
  1. Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
  2. Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
  3. Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
  4. Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
  5. Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
  6. Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
  7. Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
  8. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  9. Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
  10. Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
  11. Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
  12. The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
  13. Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
  14. Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
  15. Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
  16. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
  17. Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
  18. Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
  19. Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
  20. Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
  21. Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
  22. Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
  23. Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
  24. Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
  25. Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
  26. Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
  27. Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
  28. Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
  29. Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
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Policosanol 15 references
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Hawthorn 25 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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