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Dietary supplement

Oregano Leaf Ingredients & Drug Interactions

by Cedar Bear

Oregano Leaf label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oregano Leaf against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oregano Leaf is a dietary supplement by Cedar Bear with 1 active ingredient. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Oregano Leaf by Cedar Bear

Ask about any prescription or over-the-counter medication and we check it for interactions with Oregano Leaf by Cedar Bear — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Oregano Leaf by Cedar Bear

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (0.50 mL) without saying how much of each component you get.

This liquid supplement contains one active ingredient: oregano leaf. The extract is made with vegetable glycerine and purified water as inactive ingredients.

Oregano is an herb in the mint family, traditionally used for flavor and as a folk remedy for various respiratory and digestive complaints.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Oregano product and its label doesn't state a use — see Oregano's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that oregano works reliably for acne, bronchitis, asthma, headache, or upper respiratory tract infections — the data rates all of these as having insufficient reliable evidence. If you're considering this product for one of those uses, talk it over with your doctor or pharmacist to explore what the current research actually shows.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

In food amounts, oregano is well tolerated — gastrointestinal upset is the most common side effect when larger doses are used. Concentrated oregano oil supplements are stronger and less studied than food-level use.

Rare but serious allergic reactions, including anaphylaxis, have been reported in sensitive individuals. During pregnancy, medicinal or supplement amounts should be avoided, though normal food amounts are likely fine.

While breastfeeding, the safety of oregano supplements isn't established — food amounts are a different story, but for supplement use, there isn't enough data. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs — oregano may increase bleeding risk. Also confirm if you're on diabetes medication, as oregano might lower blood sugar and add to your medication's effect.

Altogether, these interactions span 208 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Cedar Bear Oregano Leaf is a single-herb liquid that's generally well tolerated in typical amounts but carries Moderate interaction risks with blood thinners and diabetes drugs. If you take either of those, or any other regular medication, check with your doctor or pharmacist first.

The evidence for its effectiveness on cough, asthma, or similar complaints is too thin to rely on at this point.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oregano Leaf, straight from the product label.

Brand Cedar Bear
Barcode (UPC) 834711004145
Net contents 60 mL; 2 fl. Oz.
Market status On market
Date entered into DSLD Nov 21, 2020
DSLD ID 239306
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oregano Leaf by Cedar Bear, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 mL
Maximum serving Sizes:
0.5 mL
Servings per container
120
UPC/BARCODE
834711004145
IngredientAmount% DV
Proprietary Blend0.5 mL--
Oregano0 NP--

Other ingredients: USP Grade Vegetable Glycerine, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Manufactured in the USA

True Alcohol Free Sugar Free Gluten Free

Vegan

Suggested/Recommended/Usage/Directions

Suggested Use: .5 mL (10 drops) 1 to 3 times a day, or as needed. Shake well.

Precautions

Note: Consult your physician before use.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practices K (Kosher)

Formula

K (Kosher)

Origanum vulgare

General Statements

Herbal single

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oregano Leaf by Cedar Bear label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oregano Leaf label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oregano Leaf by Cedar Bear

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Proprietary Blend

0.5 mL per serving

Other (inactive) ingredients: USP Grade Vegetable Glycerine, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oregano Leaf by Cedar Bear Drug Interactions

Want to check YOUR meds against Oregano Leaf?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Oregano 208

Individual Drug Interactions

The ingredients in Oregano Leaf interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in Oregano Leaf interact with drugs. Each result below shows which ingredient is responsible. Oregano

Each ingredient & the kinds of drugs it affects

For each ingredient in Oregano Leaf with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
Oregano full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oregano Leaf, from the product label.

Cedar Bear

See all Cedar Bear products
Name
Cedar Bear Naturales INC
Street Address
PO Box 158
City
Roosevelt
State
UT
ZipCode
84066
Phone Number
1-888-854-3727
Web Address
Cedarbear.com
Pharmacist Counseling Corner

Oregano Leaf by Cedar Bear: Common Questions

Does Oregano Leaf by Cedar Bear interact with any medications?
Yes. Based on its ingredients, Oregano Leaf has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oregano Leaf contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is oregano safe during pregnancy?
Food amounts of oregano are likely fine, but medicinal or supplement amounts should be avoided during pregnancy. If you're pregnant and thinking about taking this product, talk with your doctor or pharmacist first.
Can I use this while breastfeeding?
The safety of oregano supplements while breastfeeding isn't established — we don't have enough data either way. Stick to normal food amounts, and ask your doctor or pharmacist whether this supplement is okay for you.
Does oregano actually help with cough or bronchitis?
The evidence we have doesn't reliably support that it does. The data rates oregano for bronchitis, asthma, and upper respiratory infections as having insufficient reliable evidence to recommend it.
What are the side effects?
In typical amounts, oregano is well tolerated. The most common side effect is mild gastrointestinal upset. Rarely, sensitive people have had allergic reactions, including serious ones like anaphylaxis.
Is this safe if I take blood thinner medication?
No — oregano may increase your bleeding risk when combined with blood thinners or antiplatelet drugs. Check with your doctor or pharmacist before taking this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oregano Leaf is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oregano Leaf label
Go deeper

The Full Monographs Behind Oregano Leaf’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oregano Leaf's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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