Major interaction on record — check this product against your medications before combining. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Organic Mucuna Ingredients & Drug Interactions

by Himalaya

Organic Mucuna label
See full label image
Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Mucuna against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Organic Mucuna is a dietary supplement by Himalaya with 2 active ingredients. Its ingredients are commonly taken for parkinson's disease symptoms, male fertility and libido, mood and stress support.Based on those ingredients, 193 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are organic Velvet Bean powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Mucuna by Himalaya

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Mucuna by Himalaya — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Mucuna by Himalaya

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Organic Mucuna by Himalaya contains 2 active ingredients: organic velvet bean powder and organic velvet bean extract. Both come from the same plant source (Cowhage) and both contain levodopa, the same active compound used in prescription Parkinson's medications.

The product has no inactive fillers listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cowhage's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports relaxation and mood with tension release.
  • We looked for evidence on: Anxiety, Parkinson disease, Sexual desire, stress, mood disorders.
  • The closest evidence on file: Cowhage is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Cowhage is rated "Insufficient Reliable Evidence To Rate" for Parkinson disease, Sexual desire.

The evidence supporting this product is not established. The data we hold rates all six conditions listed—anxiety, skin redness (erythema), high prolactin levels (hyperprolactinemia), muscle pain (myalgia), Parkinson disease, and rheumatoid arthritis—as having insufficient reliable evidence to rate.

That means the science doesn't yet support claims about whether it works for any of these uses.

The evidence, ingredient by ingredient Cowhage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Because this product contains levodopa, an active drug-like compound, it requires careful use and professional guidance. Side effects from taking it orally seem rare overall, but some people report diarrhea, gas, or irritation of the mouth lining.

At higher doses (22.5–67.5 grams daily), a specific extract formulation caused nausea, belly bloating, and vomiting in clinical trials; insomnia occurred in roughly 3% of those patients, and headaches have also been reported. Pregnancy safety data are insufficient, and because of levodopa's effects on hormones, the safety data advise against use during pregnancy.

During breastfeeding, levodopa can lower prolactin and reduce milk supply—so avoid it while nursing. Talk with your doctor or pharmacist about whether this product is right for your situation.

Side effects, ingredient by ingredient Cowhage

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cowhage.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; Parkinson's medications.
  • For scale: 193 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take methyldopa or any non-selective monoamine oxidase inhibitors (MAOIs) or levodopa itself—these carry Major-severity risks. Also double-check if you're on blood sugar drugs, antipsychotics, tricyclic antidepressants, guanethidine, or will be having surgery with certain anesthetics.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Organic Mucuna is a velvet bean supplement containing levodopa, which means it works like an active medication and carries serious interactions with blood pressure drugs, certain antidepressants, diabetes medications, and antipsychotics. The evidence for whether it actually works for anxiety, Parkinson disease, or the other conditions listed isn't established yet.

Before you take it, check with your doctor or pharmacist about your exact medications and whether this is appropriate for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Mucuna, straight from the product label.

Brand Himalaya
Barcode (UPC) 605069427012
Net contents 60 Caplet(s)
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 282989
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Mucuna by Himalaya, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
1 Caplet(s)
Servings per container
60
UPC/BARCODE
605069427012
IngredientAmount% DV
organic Velvet Bean powder350 mg--
organic Velvet Bean extract250 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

No wheat, corn or dairy. No ingredients of animal origin. Gluten free

Vegan friendly

cGMP

Certified Organic by Control Union Certifications, CU 867461

Product of India

Mucuna supports relaxation while promoting mood and release of physical tension.

2 month supply

Supports relaxation & restoration Benefits the nervous system

Non GMO Project Verified nongmoproject.org

USDA Organic

In the ancient Ayurvedic texts, Mucuna was called Atmagupta, or secret self within, possibly alluding to the seeds hidden inside the pod but perhaps also to its effect on the mind. Research has shown that within Mucuna seeds are naturally occurring compounds that act as precursors to vital neurotransmitters responsible for pleasure, muscle movement and sleep.

General Statements

Neutral Code No.: KR/Drugs/DLA AUS-83 Mfg. Lic. No. AUS-83 Questions? Please call 1-800-869-4640 or visit www.himalayausa.com

Our cartons are made from 100% recycled fibers, including 40% post-consumer material. Our glass bottles contain at least 48% recycled content.

HUS-5050044 Happiness through wellness Crafting traditional medicines based on Ayurveda, a 5,000 year old science that believes the journey back to wholeness begins with nurturing the capacity for joy. Trusting the gifts of nature and the irreplaceable relationship between the plant and its native soil for consistent healing properties. Contributing to the wellness of the earth by teaching our family of farmers to grow native plants sustainably on their land and reduce the demand on the local environment. Building communities by advocating women in farming, protecting fair prices, providing maternal health, sponsoring clinical services and offering school wellness programs. Believing that if wellness is the path to happiness, we must contribute to the wellness of all things. Wellness of people, wellness of the environment, wellness of our communities. Family owned for over 90 years

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Recommended use: Adults take 1 caplet per day before food.

Precautions

Caution: As with any supplement, consult a healthcare practitioner before use if you are pregnant, nursing, taking medication, have a medical condition or are planning any medical procedure.

Discontinue use and consult a healthcare practitioner if any adverse reactions occur.

Keep out of reach of children.

Brand IP Statement(s)

Himalaya since 1930

Seals/Symbols

Non GMO Project Verified nongmoproject.org USDA Organic

FDA Statement of Identity

Herbal Supplement

Formula

Featured herb on front: Mucuna (seeds & aerial parts)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Mucuna by Himalaya label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Mucuna label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Mucuna by Himalaya

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic Velvet Bean powder

Interacts with
193 drugs
350 mg per serving

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...

Organic Velvet Bean powder monograph & interactions

Organic Velvet Bean extract

Interacts with
193 drugs
250 mg per serving

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...

Organic Velvet Bean extract monograph & interactions
Interaction report

Organic Mucuna by Himalaya Drug Interactions

Want to check YOUR meds against Organic Mucuna?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
193Drugs
17 Major 176 Moderate

Ingredients driving the most interactions

organic Velvet Bean powder 193

Individual Drug Interactions

The ingredients in Organic Mucuna interact with 193 drugs. Click any drug to see the details.

1 of the 2 ingredients in Organic Mucuna interact with drugs. Each result below shows which ingredient is responsible. organic Velvet Bean powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Mucuna with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Velvet Bean powder8 drug types · 193 drugs

Levodopa

Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.

Likelihood Likely Evidence D
Methyldopa (Aldomet)

Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.

Likelihood Probable Evidence D
Anesthesia

Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.

Likelihood Possible Evidence D
Antipsychotic Drugs

Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.

Likelihood Possible Evidence D
Guanethidine (Ismelin)

Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.

Likelihood Probable Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.

Likelihood Possible Evidence D
organic Velvet Bean powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Mucuna, from the product label.

Himalaya

See all Himalaya products
Name
Himalaya Wellness USA Ltd.
Street Address
1101 Gillingham Lane
City
Sugar Land
State
Texas
ZipCode
77478
Phone Number
1-800-869-4640
Web Address
www.himalayausa.com
Pharmacist Counseling Corner

Organic Mucuna by Himalaya: Common Questions

Does Organic Mucuna by Himalaya interact with any medications?
Yes. Based on its ingredients, Organic Mucuna has a known interaction with 193 medications, including 17 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Mucuna contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is velvet bean, and why is it in this product?
Velvet bean, also called cowhage, is a plant that naturally contains levodopa—the same compound used in Parkinson's medications. This product uses the powder and extract from the bean.
Can I take this if I'm pregnant?
No—the safety data advise against it during pregnancy. There isn't enough safety data, and levodopa's effects on hormones make it best avoided. Talk with your doctor about your options.
What if I'm breastfeeding?
You should avoid this product while breastfeeding. Levodopa can lower prolactin levels and reduce milk supply. Discuss alternatives with your doctor or pharmacist.
What side effects might I experience?
Most common are diarrhea, gas, and mouth irritation. At higher doses, some people reported nausea, belly bloating, vomiting, insomnia (in about 3%), and headaches. Serious adverse effects appear rare, but a full safety study hasn't been done.
Does this product actually work for Parkinson disease or anxiety?
The evidence we hold doesn't establish that it works for either one. The data rate both conditions—along with others listed—as having insufficient reliable evidence.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Mucuna is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Mucuna label
Go deeper

The Full Monographs Behind Organic Mucuna’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cowhage

Interacts with 193 drugs

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...

Read the full Cowhage monograph →
Sources

Sources & How We Checked

Organic Mucuna's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cowhage 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Anon. Epidemiological notes and reports: Mucuna pruriens-associated pruritus--New Jersey. MMWR Morb Mortal Wkly Rep 1985;34:732-3.
  4. HP-200 in Parkinson's Disease study group. An alternative medicine treatment for Parkinson's disease: Results of a multicenter clinical trial. J Alt Comp Med 1995;1:249-55. DOI
  5. Infante ME, Perez AM, Simao MR, et al. Outbreak of acute toxic psychosis attributed to Mucuna pruriens. Lancet 1990;336:1129. PubMed
  6. Vaidya AB, Rajagopalan TG, Mankodi NA, et al. Treatment of Parkinson's disease with the cowhage plant-Mucuna pruriens Bak. Neurol India 1978;26:171-6.
  7. Vadivel V, Janardhanan K. Nutritional and anti-nutritional composition of velvet bean: an under-utilized food legume in south India. Int J Food Sci Nutr 2000;51:279-87. PubMed
  8. Akhtar MS, Qureshi AQ, Iqbal J. Antidiabetic evaluation of Mucuna pruriens, Linn seeds. J Pak Med Assoc 1990;40:147-50.
  9. Prakash, D., Niranjan, A., and Tewari, S. K. Some nutritional properties of the seeds of three Mucuna species. Int.J.Food Sci.Nutr. 2001;52(1):79-82.
  10. Vadivel, V. and Janardhanan, K. Nutritional and antinutritional characteristics of seven South Indian wild legumes. Plant Foods Hum.Nutr 2005;60(2):69-75. PubMed
  11. Creapure (Creatine Monohydrate). Toxicological Datasheet. Degussa BioActives. Available at: https://www.fda.gov/ohrms/DOCKETS/.../95s-0316-rpt0154-54-Ref-50-vol112.pdf.
  12. Pulikkalpura H, Kurup R, Mathew PJ, Baby S. Levodopa in Mucuna pruriens and its degradation. Sci Rep 2015;5:11078. PubMed

See these in context on the Cowhage monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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