Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Peak SX-7 Ingredients & Drug Interactions

by MuscleTech

Capsule Category: Other Combinations
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Peak SX-7 is a dietary supplement by MuscleTech with 2 active ingredients. Its ingredients are commonly taken for energy and cellular function support, athletic performance and muscle energy, circulation support.Based on those ingredients, 261 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Longjack extract, PEAK ATP. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Peak SX-7 by MuscleTech

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Peak SX-7 contains 2 active ingredients. PEAK ATP is adenosine, a compound your cells naturally produce—it's used medically in its prescription injectable form to help diagnose heart conditions and treat certain irregular heartbeats.

Longjack extract comes from Eurycoma longifolia, a plant used in traditional medicine, often studied for effects on physical performance and sexual function. The product also contains inactive ingredients (maltodextrin, a capsule, magnesium stearate, and silicon dioxide) that serve as fillers and binders to hold the capsule together.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: muscle strength and athletic performance.
  • We looked for evidence on: Muscle strength, Athletic performance, muscle hypertrophy, lean mass gain, exercise capacity.
  • The closest evidence on file: Eurycoma Longifolia is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Adenosine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance.
  • Also on file: Eurycoma Longifolia is rated "Insufficient Reliable Evidence To Rate" for Muscle strength.

PEAK ATP (adenosine) is rated effective for diagnosing cardiovascular disease and for treating a type of irregular heartbeat called paroxysmal supraventricular tachycardia—but the data here reflects its powerful prescription injectable use under medical supervision, not this oral supplement form. Longjack extract is rated possibly effective for sexual desire.

For athletic performance, the evidence suggests it's possibly ineffective. For back pain, osteoporosis, and diabetes, there isn't enough reliable evidence to rate it.

The evidence, ingredient by ingredient Adenosine Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Safety data on oral adenosine (PEAK ATP) as a supplement is limited. The prescription injectable form is powerful and works quickly—it can cause chest pain, dizziness, shortness of breath, facial flushing, headache, low blood pressure, nausea, and a racing or irregular heartbeat.

Serious effects are rare but can include cardiac arrest and heart attacks. Oral or intramuscular forms haven't shown reported adverse effects in studies, though thorough safety testing hasn't been completed.

Longjack extract is generally well tolerated short-term in studies, but long-term safety and product quality aren't certain. It may raise testosterone levels; if levels go beyond normal, you could develop acne, insulin resistance (trouble managing blood sugar), and liver damage.

The safety data advises against use during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Adenosine Eurycoma Longifolia

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Adenosine, Eurycoma Longifolia.
  • The most serious interaction on file is rated Major.
  • For scale: 261 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Peak SX-7, check with your doctor or pharmacist if you're on dipyridamole (a heart medication causing a major interaction), carbamazepine (an anti-seizure drug causing moderate risk), or propranolol (a blood pressure medication causing moderate risk). Also let them know if you regularly consume caffeine, theophylline, or aminophylline, as these can interfere with adenosine's effects.

If you take any enzyme-processed medications or testosterone, mention that too—theoretically there's a minor risk, though it hasn't been confirmed in people yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Peak SX-7 is an oral supplement form of adenosine and Longjack extract, designed to support athletic performance and sexual function, though evidence for the latter is modest and for the former is weak. If you take heart medications (especially dipyridamole or propranolol), anti-seizure medication, or drugs processed through your liver, or if you're pregnant or breastfeeding, check with your doctor or pharmacist before taking it.

The ingredients carry real interactions with common medications, so don't start Peak SX-7 without confirming it's okay for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Peak SX-7, straight from the product label.

Brand MuscleTech
Barcode (UPC) 631656604856
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2015
DSLD ID 40234
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Peak SX-7 by MuscleTech, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
631656604856
IngredientAmount% DV
PEAK ATP400 mg--
Longjack extract100 mg--

Other ingredients: Maltodextrin, Capsule, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

THE MOST POWERFUL NON-STIMULANT PRE-WORKOUT PILL

How Does It Work? Research suggests the key compound in Peak SX-7(TM)works using three distinct pathways. The first pathway helps increase blood flow to deliver more oxygen to hard-working muscles, allowing them to work even harder. The second mechanism of action is to help your muscles control ionic flux during contractions so they can recover and contract faster. The third and most important pathway of action is when Peak SX-7(TM) triggers the anabolic mTOR pathway – this puts your muscles in “musclebuilding” mode.

Subjects Gained More Muscle & Strength Than Subjects Using a Placebo in a 12-week Clinical Study Researchers at the prestigious University of Tampa conducted a randomized, double-blind, placebo-controlled clinical study done over 12 weeks on very well-trained athletes. 1Subjects gained 8.8 lbs. of lean muscle versus the placebo group, who only gained 4.6 lbs. The results were breakthrough!

THE MOST POWERFUL NON-STIMULANT PRE-WORKOUT PILL SUBJECTS GAINED 8.8 LBS. OF LEAN MUSCLE IN 12 WEEKS,1 147% INCREASE IN MUSCLE STRENGTH, 2 FORMULATED WITH PATENTED PEAK ATP(R) RESEARCHED AT THE UNIVERSITY OF TAMPA

Protected by patent #6,723,737, 7,671,038, and 7,629,329.

muscletechsx7.com Twitter @muscletech facebook.com/muscletech

Uses of ATP are licensed to Iovate by TSI USA Inc. under U.S. Patent numbers 6,723,737, 7,671,038, and 7,629,329.

Made in the U.S.A. from international ingredients.

Research & development

NEW CLINICALLY TESTED KEY INGREDIENT

Brand IP Statement(s)

Peak SX-7(TM) is the most powerful pre-workout pill on the market today. Many pre-workout pills and powders give you energy and a “buzz,”– but how many can legitimately help you add lean muscle and extreme strength gains in just 12 weeks? Time to leave your old pre-workout behind.

{chart} Weight (lbs.) 120 100 80 60 40 121.9 lbs. PEAK SX-7(TM) 49.4lbs. PLACEBO 147% STRENGTH INCREASE STRENGTH INCREASE IN 12 WEEKS (TOTAL STRENGTH ON BENCH, SQUAT, & DEADLIFT) MOST POWERFUL NON-STIMULANT PRE-WORKOUT PILL 2Subjects using the key compound in the Peak SX-7(TM) formula increased their total strength by an average of 121.9 lbs. in 12 weeks. The placebo group only increased by an average of 49.4 lbs. With Peak SX-7(TM) you’ll get stronger and more powerful.

Peak SX-7(TM) is manufactured according to cGMP standards, as is required for all dietary supplements.

Peak ATP(R) is a registered trademark of TSI USA Inc. and is used under license.

(C) 2014.

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

Directions: Take 1 serving (2 capsules) daily 30 to 45 minutes before your workout. On non-training days, take 1 serving (2 capsules) on an empty stomach before breakfast. Do not exceed 2 capsules in a 24-hour period. Read the entire label before use and follow directions provided.

Precautions

WARNING: Not intended for use by persons under 18.

Do not use if pregnant or nursing.

Consult a medical doctor before starting a diet or exercise program. Discontinue use 2 weeks prior to surgery.

KEEP OUT OF REACH OF CHILDREN.

Do not use if packaging has been tampered with.

Storage

Store in a cool, dry place (60(0)F to 80(0)F).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

MADE IN THE USA FROM INTERNATIONAL INGREDIENTS

PEAK ATP(R)

FORMULA EXCLUSIVE TO MUSCLETECH(R)

General

10355US 0614

See for yourself

Peak SX-7 by MuscleTech label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Peak SX-7 by MuscleTech

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

PEAK ATP

Interacts with
47 drugs
400 mg per serving

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat...

PEAK ATP monograph & interactions

Longjack extract

Interacts with
248 drugs
100 mg per serving Form: Eurycoma longifolia

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

Longjack extract monograph & interactions

Other (inactive) ingredients: Maltodextrin, Capsule, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Peak SX-7 by MuscleTech Drug Interactions

Want to check YOUR meds against Peak SX-7?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
261Drugs
2 Major 4 Moderate 255 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Peak SX-7 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Longjack extract5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D

PEAK ATP3 drug types · 47 drugs

Dipyridamole (Persantine)

Dipyridamole can increase the therapeutic and toxic effects of adenosine.
Dipyridamole decreases the metabolism of adenosine. Intravenous infusion of adenosine in patients who are taking dipyridamole can cause dizziness, bradycardia, and syncope. Dipyridamole should be discontinued for several days prior to a cardiac stress test using adenosine.

Likelihood Likely Evidence D
Carbamazepine (Tegretol)

Carbamazepine might increase the risk of heart block when used concomitantly with adenosine.
Carbamazepine and adenosine can both cause heart block. Giving them concurrently might produce an additive effect.

Likelihood Possible Evidence D
Methylxanthines

Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
The methylxanthines, aminophylline, caffeine, and theophylline, can block the effects of adenosine by acting as competitive antagonists at adenosine cell surface receptors. It is recommended that methylxanthines be avoided for 24 hours prior to cardiac stress tests.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Peak SX-7, from the product label.

MuscleTech

See all MuscleTech products
Name
Iovate Health Sciences U.S.A. Inc.
Street Address
1105 N. Market St., Ste. 1330
City
Wilmington
State
DE
ZipCode
19801
Pharmacist Counseling Corner

Peak SX-7 by MuscleTech: Common Questions

Does Peak SX-7 by MuscleTech interact with any medications?
Yes. Based on its ingredients, Peak SX-7 has a known interaction with 261 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Peak SX-7 contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is PEAK ATP?
PEAK ATP is adenosine, a compound your body makes naturally. Doctors use the prescription injectable form to diagnose heart problems and treat certain irregular heartbeats. This supplement is an oral form of that same ingredient, but the safety and strength data are different from the prescription version.
What does Longjack extract do?
Longjack is an extract from Eurycoma longifolia, a plant studied mainly for sexual function and athletic performance. The evidence supports it as possibly effective for sexual desire, but for athletic performance the evidence suggests it doesn't work, and there isn't enough data on back pain, osteoporosis, or diabetes.
Can I take Peak SX-7 while pregnant or breastfeeding?
The safety data advises against both. There isn't enough information on adenosine safety in pregnancy or breastfeeding, and Longjack extract carries safety concerns (including possible hormonal effects) that make it best to avoid during pregnancy and breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you.
What are the side effects?
The prescription injectable form of adenosine can cause chest pain, dizziness, shortness of breath, facial flushing, headache, low blood pressure, nausea, and irregular heartbeats. Serious effects like cardiac arrest are rare. Oral adenosine hasn't shown reported side effects in studies, though full safety testing is incomplete. Longjack extract may raise testosterone, which could lead to acne, insulin resistance, or liver issues if levels get too high.
Will caffeine interfere with Peak SX-7?
Yes—caffeine and other methylxanthines (like theophylline in some asthma medications) can block adenosine's effects. If you're taking Peak SX-7, it's recommended to avoid caffeine for 24 hours beforehand, especially if you're about to have any adenosine-based heart tests.
Does Peak SX-7 have any fillers?
It contains inactive ingredients: maltodextrin, magnesium stearate, silicon dioxide, and a capsule material. These are standard binders and fillers that help make the capsule, not active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Peak SX-7 label
Sources

Sources & How We Checked

Peak SX-7's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Adenosine 10 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Agteresch HJ, Dagnelie PC, van den Berg JW, Wilson JH. Adenosine triphosphate: established and potential clinical applications. Drugs 1999;58:211-32.. PubMed
  3. Agteresch HJ, Dagnelie PC, van der Gaast A, et al. Randomized clinical trial of adenosine 5'-triphosphate in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2000;92:321-8.. PubMed
  4. Haskell CM, Wong M, Williams A, Lee LY. Phase I trial of extracellular adenosine 5'-triphosphate in patients with advanced cancer. Med Pediatr Oncol 1996;27:165-73.. DOI
  5. Haskell CM, Mendoza E, Pisters KM, et al. Phase II study of intravenous adenosine 5'-triphosphate in patients with previously untreated stage IIIB and stage IV non-small cell lung cancer. Invest New Drugs 1998;16:81-5.. PubMed
  6. Eisenach JC, Curry R, Hood DD. Dose response of intrathecal adenosine in experimental pain and allodynia. Anesthesiology 2002;97:938-42.. PubMed
  7. Agteresch HJ, Dagnelie PC, Rietveld T, et al. Pharmacokinetics of intravenous ATP in cancer patients. Eur J Clin Pharmacol 2000;56:49-55.. PubMed
  8. Underwood DA. Which medications should be held before a pharmacologic or exercise stress test? Cleve Clin J Med 2002;69:449-50. PubMed
  9. Litmann L, Anderson JD, Monroe MH. Adenosine and Aggrenox: A hazardous combination. Ann Intern Med 2002;137:E-76. PubMed
  10. Faghihi G, Iraji F, Rajaee Harandi M, et al. Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenic alopecia and measuring patient satisfaction rate. Acta Dermatovenerol Croat 2013;21(3):155-9.

See these in context on the Adenosine monograph →

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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