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Dietary supplement

Premium CBD Oil 1500 mg Ingredients & Drug Interactions

by cbdMD

Premium CBD Oil 1500 mg label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Premium CBD Oil 1500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Premium CBD Oil 1500 mg is a dietary supplement by cbdMD with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 940 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Broad Spectrum Hemp Aerial Parts, Flower Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Premium CBD Oil 1500 mg by cbdMD

Ask about any prescription or over-the-counter medication and we check it for interactions with Premium CBD Oil 1500 mg by cbdMD — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Premium CBD Oil 1500 mg by cbdMD

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: broad spectrum hemp aerial parts and flower extract at 1500 mg per serving. Broad spectrum means it includes a range of compounds naturally found in hemp plant material.

The inactive ingredients — medium chain triglyceride oil, gelatin, glycerin, water, D-limonene, and mixed tocopherols — are the capsule and carrier; they help deliver the active extract but don't add therapeutic effect.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hemp product and its label doesn't state a use — see Hemp's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for hemp extract isn't established in our data. The facts we hold list several conditions — constipation, atopic dermatitis (eczema), and familial hypercholesterolemia (high cholesterol due to genetic factors) — but for all of them, the rating is insufficient reliable evidence to know whether it works.

That doesn't mean it doesn't; it means the research isn't there yet to say one way or the other.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods are generally well tolerated, but this product is a concentrated extract, which is less studied. The safety data advises caution with concentrated supplements like this one.

Serious adverse effects are rare but include allergic reactions — uncommon cases of anaphylaxis, facial swelling, and breathing trouble have been reported, as well as very rare heart rhythm problems. A case report in a young child given high-dose hemp extract showed elevated liver enzymes and hepatitis, though this involved doses much higher than a typical supplement.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 941 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check if you're on estrogen or hormone therapy — hemp may interfere with how it works. Also double-check blood pressure medications (antihypertensives and ACE inhibitors), blood thinners or antiplatelet drugs, and any medication your liver breaks down, since hemp may reduce how well those work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're not on hormone therapy or blood pressure medications, this product may be worth a try, but the evidence for what it does isn't solid yet. Anyone on estrogen therapy, blood pressure drugs, blood thinners, or medications metabolized by the liver should check with us before starting.

Talk to your pharmacist about your specific medications first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Premium CBD Oil 1500 mg, straight from the product label.

Brand cbdMD
Barcode (UPC) 840287702705
Net contents 30 Softgel(s); 0.7 Ounce(s); 19 Gram(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 326507
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Premium CBD Oil 1500 mg by cbdMD, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
UPC/BARCODE
840287702705
IngredientAmount% DV
Broad Spectrum Hemp Aerial Parts, Flower Extract51 mg--

Other ingredients: Medium Chain Triglyceride Oil, Gelatin, Glycerin, Water, D-Limonene, Mixed Tocopherols

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Batch-tested to ensure no detectable THC.

Precautions

State laws requires these warnings: Warnings: Consuming this product can expose you to chemicals including myrcene, which is known to the State of California to cause cancer, and THC, which is known to the State of California to cause birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov/food. This product is derived from hemp and may contain THC which could result in the consumer failing a drug test for marijuana.

Keep out of reach of children.

If pregnant or breastfeeding, ask a professional before use.

Must be 18 and over to purchase or use this product.

Intended for short term use only.

Caution: Do not exceed suggested use. Do not use if safety seal over cap is broken,

Please consult a medical professional before use if you have a medical condition or take medication.

If you experience any adverse symptoms after use, discontinue and consult a medical professional. Warning: May cause drowsiness

Formula

Product contains a total delta-9 tetrahydrocannabinol concnetration that does not exceed 0.3% on a dry weight basis.

50 mg CBD per softgel

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

NSF Certified Sport

Suggested/Recommended/Usage/Directions

Suggested use: Take one serving daily.

Storage

Storage: Keep away from heat, light and humidity to preserve freshness.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Premium CBD Oil 1500 mg by cbdMD label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Premium CBD Oil 1500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Premium CBD Oil 1500 mg by cbdMD

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Broad Spectrum Hemp Aerial Parts, Flower Extract

Interacts with
940 drugs
51 mg per serving Form: Broad Spectrum Hemp Aerial Parts Extract, Broad Spectrum Hemp Flower Extract

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Broad Spectrum Hemp Aerial Parts, Flower Extract monograph & interactions

Other (inactive) ingredients: Medium Chain Triglyceride Oil, Gelatin, Glycerin, Water, D-Limonene, Mixed Tocopherols. These complete the product’s ingredient list but are not active constituents.

Interaction report

Premium CBD Oil 1500 mg by cbdMD Drug Interactions

Want to check YOUR meds against Premium CBD Oil 1500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
940Drugs
41 Moderate 899 Minor

Ingredients driving the most interactions

Broad Spectrum Hemp Aerial Parts, Flower Extract 940

Individual Drug Interactions

The ingredients in Premium CBD Oil 1500 mg interact with 940 drugs. Click any drug to see the details.

1 of the 1 ingredient in Premium CBD Oil 1500 mg interact with drugs. Each result below shows which ingredient is responsible. Broad Spectrum Hemp Aerial Parts, Flower Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Premium CBD Oil 1500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Broad Spectrum Hemp Aerial Parts, Flower Extract6 drug types · 940 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Broad Spectrum Hemp Aerial Parts, Flower Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Premium CBD Oil 1500 mg, from the product label.

cbdMD

See all cbdMD products
Name
cbdMD
City
Charlotte
State
NC
ZipCode
28217
Phone Number
1-800-973-3984
Web Address
www.cbdMD.com
Pharmacist Counseling Corner

Premium CBD Oil 1500 mg by cbdMD: Common Questions

Does Premium CBD Oil 1500 mg by cbdMD interact with any medications?
Yes. Based on its ingredients, Premium CBD Oil 1500 mg has a known interaction with 940 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Premium CBD Oil 1500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is CBD oil safe if I'm not on any medications?
For people not on medications, the data shows hemp products are generally well tolerated. That said, this is a concentrated extract, not a food amount, so it's less studied than whole hemp seed. Rare allergic reactions — including anaphylaxis — have been reported. If you have a known allergy to hemp seed or any concerns, talk to your pharmacist first.
What's the difference between this and regular hemp seed oil?
This is a concentrated extract in a capsule, whereas hemp seed oil is the pressed oil from seeds. Concentrated extracts are less well studied than food amounts of hemp seed. The safety data we have is stronger for hemp seed foods than for supplements like this one.
Can this help with my eczema or cholesterol?
The evidence isn't established yet. We hold ratings that say insufficient reliable evidence for both atopic dermatitis (eczema) and familial hypercholesterolemia (high cholesterol). That means we don't have enough research to say whether it works for these.
Are there any side effects I should watch for?
Hemp products are generally well tolerated, but allergic reactions — including hives, facial swelling, and breathing trouble — can happen, though they're uncommon. In very rare cases, heart rhythm problems and syncope (fainting) have been reported. A single case in a child given very high doses showed liver enzyme changes. Contact your doctor or pharmacist if you notice any unusual symptoms.
Is this safe during pregnancy or while breastfeeding?
We don't have safety data on file for hemp extract during pregnancy or lactation. Because this is a concentrated supplement and not a food amount, we can't say whether it's safe either way. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to be, or breastfeeding.
Does this product have any fillers?
Yes. The inactive ingredients are medium chain triglyceride oil, gelatin, glycerin, water, D-limonene, and mixed tocopherols. These help deliver the hemp extract and form the capsule, but they're not the active ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Premium CBD Oil 1500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Premium CBD Oil 1500 mg label
Go deeper

The Full Monographs Behind Premium CBD Oil 1500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hemp

Interacts with 940 drugs

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...

Read the full Hemp monograph →
Sources

Sources & How We Checked

Premium CBD Oil 1500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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