Protect Hemp + Lunarich X 500 mg Peppermint Blast Ingredients & Drug Interactions
by RLV
What is this page for?
First and foremost: checking Protect Hemp + Lunarich X 500 mg Peppermint Blast against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Protect Hemp + Lunarich X 500 mg Peppermint Blast is a dietary supplement by RLV with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Broad Spectrum Hemp extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Protect Hemp + Lunarich X 500 mg Peppermint Blast by RLV
Ask about any prescription or over-the-counter medication and we check it for interactions with Protect Hemp + Lunarich X 500 mg Peppermint Blast by RLV — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Protect Hemp + Lunarich X 500 mg Peppermint Blast by RLV
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This liquid contains 2 active ingredients. Broad spectrum hemp extract is derived from the hemp plant and includes a range of its naturally occurring compounds.
The product also contains LunaRich X, a proprietary lunasin extract—we don't have specific details on what role it plays in this formulation. The rest is inactive ingredients (fillers and carriers): purified water, glycerin, MCT oil, natural flavors, lecithin, and a few others that help deliver the actives.
Does it work?
Couldn't assess
The evidence we hold doesn't establish that broad spectrum hemp extract is effective for the conditions listed—constipation, atopic dermatitis (eczema), and familial hypercholesterolemia (a genetic cholesterol disorder) all show insufficient reliable evidence to rate. We also have no effectiveness data on file for LunaRich X proprietary lunasin extract.
If you're considering this product for a specific health goal, talk it over with your doctor or pharmacist about what the current science actually supports.
How safe is it?
Well-documented data
Hemp seed foods in normal dietary amounts are generally well tolerated. However, concentrated extracts like the one in this product are less studied, so caution is advised.
Most people taking hemp products experience no side effects, though rarely, allergic reactions including hives, facial swelling, and anaphylaxis have been reported. There's also a rare case report of liver inflammation in a young child given very high doses of hemp extract.
Pregnancy and lactation safety data is not on file for this ingredient, so if you're pregnant or breastfeeding, talk with your doctor or pharmacist before taking it. We have no safety data on file for LunaRich X.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take hormone therapy (estrogens)—hemp may interfere with its effects. Also confirm any blood pressure medications (antihypertensives or ACE inhibitors), blood thinners (anticoagulants or antiplatelet drugs), or medications your liver processes via CYP1A2 or CYP3A4 enzymes, since hemp may reduce how well they work.
If you're unsure whether a drug is processed by these liver pathways, ask your pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is marketed for several conditions, but the evidence we hold doesn't support its use for any of them yet. The bigger concern is that if you take blood pressure medications, hormone therapy, blood thinners, or any drug metabolized by your liver, hemp extract could change how those medications work.
Check with your own doctor or pharmacist before adding this to your routine—especially if you're on any regular prescriptions.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Protect Hemp + Lunarich X 500 mg Peppermint Blast, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Protect Hemp + Lunarich X 500 mg Peppermint Blast by RLV, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Broad Spectrum Hemp extract | 16.67 mg | -- |
| LunaRich X Proprietary Liquid Lunasin Extract | 20 mg | -- |
Other ingredients: purified Water, Glycerin, Kolliphor, organic MCT Oil, Natural Flavors, Lecithin, Rebaudioside A, E-Polylysine
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Absorbs fast for quick results
Broad Spectrum
Suggested/Recommended/Usage/Directions
Usage: Shake very well with 20 seconds. Place one dropper under tongue, hold for 60 seconds and swallow.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Warning: Keep out of reach of children.
Consult your physician if you are pregnant or nursing.
Contains: Soy, coconut.
Storage
Store at room temperature, away from humidity, heat and light.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Protect Hemp + Lunarich X 500 mg Peppermint Blast by RLV label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Protect Hemp + Lunarich X 500 mg Peppermint Blast by RLV
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Broad Spectrum Hemp extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Broad Spectrum Hemp extract monograph & interactionsLunaRich X Proprietary Liquid Lunasin Extract
Other (inactive) ingredients: Purified Water, Glycerin, Kolliphor, Organic MCT Oil, Natural Flavors, Lecithin, Rebaudioside A, E-Polylysine. These complete the product’s ingredient list but are not active constituents.
Protect Hemp + Lunarich X 500 mg Peppermint Blast by RLV Drug Interactions
HelloPharmacist Interaction Report
RLV's Protect Hemp + Lunarich X 500 mg Peppermint Blast carries documented interactions through its broad spectrum hemp extract.
The most serious concern is a moderate interaction with estrogens (hormone therapy). Hemp theoretically may interfere with how your body handles estrogen-based medications; animal research shows hemp seed can normalize estradiol levels, though the exact mechanism isn't clear yet.
Read the full breakdown — every affected drug type, severity by severity
Hemp also has minor interactions with blood pressure medications (antihypertensives and ACE inhibitors), where it might add to their effect and lower your blood pressure more than intended. There's also a theoretical minor risk of increased bleeding if you take blood thinners (anticoagulants) or antiplatelet drugs like aspirin, though human data on this is limited.
Additionally, hemp may speed up how your liver processes certain drugs metabolized by CYP1A2 and CYP3A4 enzymes, potentially reducing their effectiveness.
We couldn't check the second ingredient, LunaRich X proprietary lunasin extract, because we hold no interaction data for it. Altogether, these interactions span 939 individual medications.
Before you start this product, run your exact prescriptions through the interaction checker below.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Protect Hemp + Lunarich X 500 mg Peppermint Blast?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Protect Hemp + Lunarich X 500 mg Peppermint Blast interact with 938 drugs. Click any drug to see the details.
1 of the 2 ingredients in Protect Hemp + Lunarich X 500 mg Peppermint Blast interact with drugs. Each result below shows which ingredient is responsible. Broad Spectrum Hemp extract
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Conjugated Estrogens, Methyltestosterone interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Cyproterone Acetate, Ethinyl Estradiol interactionDesogestrel, Ethinyl EstradiolDesogen, Marvelon, Marvelon 21, Marvelon 28, Mircette, Ortho-Cept +2 more
How Desogestrel, Ethinyl Estradiol interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Desogestrel, Ethinyl Estradiol interactionDrospirenone, EstetrolNextstellis
How Drospirenone, Estetrol interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Drospirenone, Estetrol interactionDrospirenone, Ethinyl EstradiolAngeliq, Gianvi, Yasmin
How Drospirenone, Ethinyl Estradiol interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Drospirenone, Ethinyl Estradiol interactionEsterified EstrogensEstratab, Menest
How Esterified Estrogens interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Esterified Estrogens interactionEsterified Estrogens, MethyltestosteroneEstratest
How Esterified Estrogens, Methyltestosterone interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Esterified Estrogens, Methyltestosterone interactionEstradiolDivigel, Elestrin, Estrace, Estraderm, Estring, Evamist +6 more
How Estradiol interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Estradiol interactionEstradiol, MedroxyprogesteroneDivitren
How Estradiol, Medroxyprogesterone interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Estradiol, Medroxyprogesterone interactionEstradiol, Norethindrone AcetateActivella
How Estradiol, Norethindrone Acetate interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Estradiol, Norethindrone Acetate interactionEstradiol, NorgestimateOrtho-Prefest
How Estradiol, Norgestimate interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Estradiol, Norgestimate interactionEstradiol, ProgesteroneBijuvanda
How Estradiol, Progesterone interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Estradiol, Progesterone interactionEstrogenEstrogen
How Estrogen interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Estrogen interactionEstroneOrtho-Est
How Estrone interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Estrone interactionEstropipateOgen, Ortho EST
How Estropipate interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Estropipate interactionEthiny Estradiol, LevonorgestrelLogynon, Microgynon 30 ED
How Ethiny Estradiol, Levonorgestrel interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Ethiny Estradiol, Levonorgestrel interactionEthinyl EstradiolEstinyl
How Ethinyl Estradiol interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol interactionEthinyl Estradiol, DesogestrelApri, Cesia, Cyclessa, Gedarel, Kariva, Linessa +4 more
How Ethinyl Estradiol, Desogestrel interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Desogestrel interactionEthinyl Estradiol, DrospirenoneYaz
How Ethinyl Estradiol, Drospirenone interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Drospirenone interactionEthinyl Estradiol, Ethynodiol DiacetateDemulen 1/35, Demulen 1/50, Demulen Compack, Kelnor 1/35, Zovia, Zovia 1/35 +1 more
How Ethinyl Estradiol, Ethynodiol Diacetate interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Ethynodiol Diacetate interactionEthinyl Estradiol, LevonorgestrelAlesse, Alesse 21, Alesse 28, Aviane, Enpresse, Jolessa +18 more
How Ethinyl Estradiol, Levonorgestrel interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Levonorgestrel interactionEthinyl Estradiol, NorethindroneAranelle, Brevicon, Brevicon .5/35 21 day, Brevicon .5/35 28 day, Brevicon 1/35 21 day, Brevicon 1/35 28 day +50 more
How Ethinyl Estradiol, Norethindrone interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Norethindrone interactionEthinyl Estradiol, Norethindrone, Ferrous FumarateEstrostep Fe, Femcon FE, Junel Fe 1.5/30, Loestrin Fe, Loestrin Fe 1.5/30, Loestrin Fe 1/20 +3 more
How Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interactionEthinyl Estradiol, NorgestimateCilest, Mononessa, Ortho Tri-Cyclen 28, Ortho Tri-Cyclen Lo, Ortho Tri-Cylcen, Ortho-Cyclen +5 more
How Ethinyl Estradiol, Norgestimate interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Norgestimate interactionEthinyl Estradiol, NorgestrelCryselle, Lo/Ovral, Low-Ogestrel, Ogestrel 0.5/50, Ovral
How Ethinyl Estradiol, Norgestrel interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Norgestrel interactionEthinyl Estradiol, LevonogestrelLybrel
How Ethinyl Estradiol, Levonogestrel interacts with Protect Hemp + Lunarich X 500 mg Peppermint Blast — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Broad Spectrum Hemp Extract + Ethinyl Estradiol, Levonogestrel interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Protect Hemp + Lunarich X 500 mg Peppermint Blast with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Broad Spectrum Hemp extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Protect Hemp + Lunarich X 500 mg Peppermint Blast, from the product label.
RLV
See all RLV products- Name
- Reliv, Inc.
- City
- Chesterfield
- State
- MO
- ZipCode
- 63005
- Phone Number
- 1-800-735-4887
- Web Address
- Reliv.com/RLVQR
Protect Hemp + Lunarich X 500 mg Peppermint Blast by RLV: Common Questions
Does Protect Hemp + Lunarich X 500 mg Peppermint Blast by RLV interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does hemp extract actually do in this product?
Can I take this if I'm on birth control or hormone therapy?
Is hemp extract safe to take long-term?
What is LunaRich X, and does it interact with medications?
Can I take this while pregnant or breastfeeding?
Does this product contain any fillers or other inactive ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Protect Hemp + Lunarich X 500 mg Peppermint Blast is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Protect Hemp + Lunarich X 500 mg Peppermint Blast’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Protect Hemp + Lunarich X 500 mg Peppermint Blast's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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