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Dietary supplement

Spinach Extract Ingredients & Drug Interactions

by Nature's Vision

Spinach Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Spinach Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Spinach Extract is a dietary supplement by Nature's Vision with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, eye health, heart health and blood pressure.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Spinach Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Spinach Extract by Nature's Vision

Ask about any prescription or over-the-counter medication and we check it for interactions with Spinach Extract by Nature's Vision — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Spinach Extract by Nature's Vision

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Spinach Extract by Nature's Vision contains one active ingredient: spinach extract — a concentrated form of the leafy green vegetable. The capsule itself is made from gelatin and magnesium stearate, which are inactive ingredients used to hold the product together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Spinach product and its label doesn't state a use — see Spinach's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on spinach extract for its commonly claimed uses isn't yet established in the data we hold. We don't have reliable evidence to rate it for nonalcoholic fatty liver disease, cognitive function, muscle strength, obesity, or polycystic ovary syndrome.

That doesn't mean it doesn't work — it means clinical research hasn't been thorough enough yet to say either way. If you're considering it for one of these reasons, talk it over with your doctor to see if there's a better-studied option.

The evidence, ingredient by ingredient Spinach

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Spinach as a food is well tolerated and considered safe for most people, including during pregnancy and breastfeeding. Serious side effects are rare.

The one exception is infants under 4 months old, who have been reported to develop methemoglobinemia from spinach — so this product is not for babies that young. Allergic reactions are possible in sensitive individuals, and occupational exposure to spinach powder has triggered asthma and lung inflammation in some factory workers.

If you have a known spinach allergy, skip this supplement.

Side effects, ingredient by ingredient Spinach

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Spinach.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check with your doctor or pharmacist if you take warfarin (Coumadin) or any other blood thinner — spinach's vitamin K can reduce how well they work and may require a dose adjustment. Also check if you take any diabetes medication, since spinach may lower blood sugar and add to that effect.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Spinach Extract is a straightforward supplement for anyone looking for a concentrated spinach source without medication concerns. But if you take warfarin, any blood thinner, or diabetes medication, you'll want to clear it with your doctor or pharmacist first — the vitamin K and blood sugar effects do matter for those drugs.

Don't start, stop, or change how much you take without checking in with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Spinach Extract, straight from the product label.

Brand Nature's Vision
Barcode (UPC) 765203072758
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276210
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Spinach Extract by Nature's Vision, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
5 Capsule(s)
Servings per container
100
UPC/BARCODE
765203072758
IngredientAmount% DV
Spinach Extract750 mg--

Other ingredients: Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: Consult your health care professional before using this or any other dietary supplement.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

This product contains no milk, egg, peanuts, fish, wheat, yeast, gluten, sugar, flavors or preservatives.

FDA Statement of Identity

Dietary Supplement

Formula

Containing thylakoids

Suggested/Recommended/Usage/Directions

Suggested use: For best results take 2 to 5 capsules twice daily with water as a dietary supplement or as directed by your health care professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Spinach Extract by Nature's Vision label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Spinach Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Spinach Extract by Nature's Vision

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Spinach Extract

Interacts with
88 drugs
750 mg per serving

Spinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is...

Spinach Extract monograph & interactions

Other (inactive) ingredients: Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Spinach Extract by Nature's Vision Drug Interactions

Want to check YOUR meds against Spinach Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
88Drugs
88 Moderate

Ingredients driving the most interactions

Spinach Extract 88

Individual Drug Interactions

The ingredients in Spinach Extract interact with 88 drugs. Click any drug to see the details.

1 of the 1 ingredient in Spinach Extract interact with drugs. Each result below shows which ingredient is responsible. Spinach Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Spinach Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Spinach Extract2 drug types · 88 drugs

Antidiabetes Drugs

There are claims that spinach leaves have hypoglycemic effects. Evidence from clinical research suggests that consumption of a spinach-rich meal reduces post-meal blood glucose levels. Theoretically, spinach might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Spinach contains vitamin K, which can interfere with the activity of warfarin.
In human research, although eating spinach with one meal does not result in coagulation test results outside the therapeutic range, daily consumption for one week necessitates dose adjustment of warfarin. Individuals using anticoagulants should consume a consistent daily amount of spinach to maintain the effect of anticoagulant therapy.

Likelihood Possible Evidence D
Spinach Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Spinach Extract, from the product label.

Nature's Vision

See all Nature's Vision products
Name
Nature's Vision
City
Portage
State
MI
ZipCode
49002
Pharmacist Counseling Corner

Spinach Extract by Nature's Vision: Common Questions

Does Spinach Extract by Nature's Vision interact with any medications?
Yes. Based on its ingredients, Spinach Extract has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Spinach Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is spinach extract safe during pregnancy and breastfeeding?
Yes — spinach as a food is considered likely safe during both pregnancy and breastfeeding, and the data notes it provides folate during pregnancy. The one exception is infants under 4 months old, who shouldn't have spinach at all.
Can I take this if I'm allergic to spinach?
No. Allergic reactions are possible in sensitive individuals, so if you know you're allergic to spinach, this product isn't for you.
What does spinach extract actually do?
We don't have reliable evidence yet for the conditions it's commonly marketed for — things like liver health, brain function, muscle strength, or weight. The data we hold says evidence is insufficient to rate it for those uses.
Does spinach extract have side effects?
When taken as a supplement by adults, it's well tolerated with side effects rarely reported. The main cautions are allergic reactions in sensitive people and that it's not safe for infants under 4 months.
What's in the capsule besides the spinach extract?
Gelatin and magnesium stearate — these are inactive ingredients that hold the capsule together and help it dissolve.
If I only take spinach extract once, will it affect my warfarin?
One meal with spinach won't throw off your coagulation test, but the concern is daily or regular use. If you take warfarin, talk with your doctor about how to use this product safely or whether it's right for you at all.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Spinach Extract label
Go deeper

The Full Monographs Behind Spinach Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Spinach

Interacts with 88 drugs

Spinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is very safe as a food, concentrated supple...

Read the full Spinach monograph →
Sources

Sources & How We Checked

Spinach Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Spinach 6 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Karlson, B., Leijd, B., and Hellstrom, K. On the influence of vitamin K-rich vegetables and wine on the effectiveness of warfarin treatment. Acta Med Scand. 1986;220(4):347-350. PubMed
  3. Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.
  4. Schuller, A., Morisset, M., Maadi, F., Kolopp Sarda, M. N., Fremont, S., Parisot, L., Kanny, G., and Moneret-Vautrin, D. A. Occupational asthma due to allergy to spinach powder in a pasta factory. Allergy 2005;60(3):408-409. PubMed
  5. Gustafsson, K., Asp, N. G., Hagander, B., and Nyman, M. Satiety effects of spinach in mixed meals: comparison with other vegetables. Int.J.Food Sci.Nutr. 1995;46(4):327-334. PubMed
  6. Schreiber, J., Muller, E., Becker, W. M., Zabel, P., Schlaak, M., and Amthor, M. [Spinach powder-induced exogenous allergic alveolitis]. Pneumologie 1998;52(1):61-65.

See these in context on the Spinach monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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