Ultra Ingredients & Drug Interactions
by UP4
What is this page for?
First and foremost: checking Ultra against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ultra is a dietary supplement by UP4 with 7 active ingredients. Its ingredients are commonly taken for digestive health and regularity, irritable bowel syndrome (ibs), diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are B. longum, B. bifidum, L. acidophilus DDS(R)-1. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ultra by UP4
Ask about any prescription or over-the-counter medication and we check it for interactions with Ultra by UP4 — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
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HelloPharmacist Scorecard of Ultra by UP4
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 7 active ingredients.
- “A Proprietary Probiotic Blend” is a proprietary blend — the label gives one combined amount (162 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 3 of the 3 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bifidobacterium Bifidum, Bifidobacterium Longum.
- The most serious interaction on file is rated Moderate.
- For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 3 of 3.
- General safety write-ups exist for 3 of 3.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 24, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ultra, straight from the product label.
| Brand | UP4 |
|---|---|
| Net contents | 60 Vegetable Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Dec 24, 2013 |
| DSLD ID | 28836 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Halal, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ultra by UP4, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| B. longum | 0 Not Present | -- |
| B. bifidum | 0 Not Present | -- |
| L. plantarum | 0 Not Present | -- |
| B. lactis | 0 Not Present | -- |
| L. salivarius | 0 Not Present | -- |
| A Proprietary Probiotic Blend | 162 mg | -- |
| L. acidophilus DDS(R)-1 | 0 Not Present | -- |
| B. lactis HN019 | 0 Not Present | -- |
Other ingredients: Rice Dextrin, Vegetable Cellulose, Fructooligosaccharide, Vegetable Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
PROBIOTIC SUPPLEMENT
Brand IP Statement(s)
A HAPPIER INSIDE
Formula
PROBIOTICS with DDS-1
We start with exceptionally resilient, scientifically validated strains like Lactobacillus acidophilus DDS(R)-1 as a base for all of our formulas.
General Statements
50 BILLION CFU 2 MONTH SUPPLY ACID & BILE RESISTANT
SUPPORTS DIGESTIVE and IMMUNE HEALTH
~leading ~scientific ~healthy ~trusted UP4 learning more about the art, science and passion that goes into our products?
Laboratory tested to meet strict standards for potency and identity.
MADE IN USA
UP4 health. Our formulas are based on the researched and proven strains that promote the healthy bacteria in your body. With probiotics and your body in balance, the results are a happier inside.
UP4 trust. We stand on our legacy of quality. We’re dedicated to being a leader in the field and guarantee you will always get what is promised on our label. It’s what you’d expect from a company that’s all in for probiotics.
UP4 leading. We’ve been making probiotics in the USA since 1979. And it’s all we do, from creating the formulas and manufacturing to getting our products to you. For us, it’s a science, an art and definitely our passion.
UP4 science. Not all probiotic strains are created equal.
We add additional live cultures that can naturally withstand stomach acid and bile without the need for chemical coatings.
Laboratory tested to meet strict standards for potency and purity. Potency guaranteed at time of expiration.
Formulation
NON-DAIRY NON-GMO GLUTEN FREE SOY FREE PRESERVATIVE FREE
VEGAN
Seals/Symbols
{crescent moon}M(R)
OK D
vitamin angels PROUD SUPPORTER
~ As with any supplement, if you are pregnant, nursing, have a medical condition or taking medication, consult your health practitioner before use
Suggested/Recommended/Usage/Directions
DIRECTIONS: For best results take 1 capsule per day before or during meals.
Precautions
CAUTION: ~ Do not take if seal is broken
~ Keep out of reach of children
Storage
Room temperature stable for two years. Refrigerate after opening.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ultra by UP4 label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ultra by UP4
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
A Proprietary Probiotic Blend
- › B. longum
- › B. bifidum
- › L. plantarum
- › B. lactis
- › L. salivarius
- › L. acidophilus DDS(R)-1
- › B. lactis HN019
Other (inactive) ingredients: Rice Dextrin, Vegetable Cellulose, Fructooligosaccharide, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Ultra by UP4 Drug Interactions
Ultra contains 7 ingredients, and 3 of them have known drug interactions. Altogether they interact with 182 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Ultra?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ultra interact with 182 drugs. Click any drug to see the details.
3 of the 7 ingredients in Ultra interact with drugs. Each result below shows which ingredient is responsible. B. longum B. bifidum L. acidophilus DDS(R)-1
AmikacinAmikin, Arikayce
How Amikacin interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Amikacin interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Amikacin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Amoxicillin interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Amoxicillin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Amoxicillin Veterinary interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Amoxicillin Veterinary interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Amoxicillin, Clavulanate Potassium interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Amoxicillin, Clavulanate Potassium interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Amphotericin, Tetracycline interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Amphotericin, Tetracycline interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Ampicillin interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Ampicillin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Ampicillin, Sulbactam interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Ampicillin, Sulbactam interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Avibactam Sodium, Ceftazidime interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Avibactam Sodium, Ceftazidime interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Azithromycin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Azithromycin interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Aztreonam interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Aztreonam interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Bacampicillin interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Bacampicillin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Bacitracin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Bacitracin interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Benznidazole interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Benznidazole interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Capreomycin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Capreomycin interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Carbenicillin Indanyl Sodium interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Carbenicillin Indanyl Sodium interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefaclor interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefaclor interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefadroxil interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefadroxil interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefamandole interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefamandole interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefazolin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefazolin interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefdinir interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefdinir interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefditoren Pivoxil interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefditoren Pivoxil interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefepime interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefepime interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefiderocol Sulfate Tosylate interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefiderocol Sulfate Tosylate interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefixime interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefixime interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefmetazole interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefmetazole interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefonicid interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefonicid interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
B. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefoperazone interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefoperazone interactionL. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Ultra — through 3 ingredients. Tap an ingredient for the detail:
L. Acidophilus Dds(r)-1Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus Dds(r)-1 + Cefotaxime interactionB. LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Longum + Cefotaxime interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ultra with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
B. longum
Antibiotic Drugs
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.
B. bifidum
Antibiotic Drugs
Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.
L. acidophilus DDS(R)-1
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Brand information
Manufacturer and brand details for Ultra, from the product label.
UP4
See all UP4 products- Name
- UASLifeSciences The Probiotic Company(R)
- Street Address
- 555 N 72nd Avenue
- City
- Wausau
- State
- WI
- ZipCode
- 54401
- Phone Number
- 715.849.3333
Ultra by UP4: Common Questions
Does Ultra by UP4 interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ultra is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ultra’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bifidobacterium Longum
Interacts with 182 drugsBifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...
Read the full Bifidobacterium Longum monograph → Herb & supplement monographBifidobacterium Bifidum
Interacts with 182 drugsBifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...
Read the full Bifidobacterium Bifidum monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph →Sources & How We Checked
Ultra's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 43 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bifidobacterium Longum 21 references
- Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
- Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
- Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
- Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
- Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
- Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
- Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
- Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
- Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
- Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed
See these in context on the Bifidobacterium Longum monograph →
Bifidobacterium Bifidum 7 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
See these in context on the Bifidobacterium Bifidum monograph →
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC