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Dietary supplement

Umckaloabo Ingredients & Drug Interactions

by Herb Pharm

Umckaloabo label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Umckaloabo against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Umckaloabo is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for acute bronchitis, common cold, sinusitis.Based on those ingredients, 241 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Umckaloabo liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Umckaloabo by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Umckaloabo by Herb Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Umckaloabo by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

Umckaloabo contains one active ingredient: a liquid extract of Umckaloabo (Pelargonium sidoides), a plant root traditionally used for respiratory health. The extract is prepared in certified organic grain alcohol, distilled water, and vegetable glycerine.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports healthy sinus nasal bronchial function.
  • We looked for evidence on: Acute Bronchitis, Rhinosinusitis, Tonsillopharyngitis, Upper respiratory tract infection (URTI), sinusitis, nasal congestion — and 2 related terms.
  • The strongest evidence on file: Umckaloabo is rated "Possibly Effective" for Acute Bronchitis (Natural Medicines).
  • Also on file: Umckaloabo is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Rhinosinusitis, Tonsillopharyngitis.

The evidence supports Umckaloabo for acute bronchitis—it's rated possibly effective for this condition. For chronic obstructive pulmonary disease (COPD), the research is also rated possibly effective.

However, for sore throat and tonsil inflammation (tonsillopharyngitis), we don't have enough reliable evidence to rate it either way.

The evidence, ingredient by ingredient Umckaloabo

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Umckaloabo is generally well tolerated for short-term use, though quality and standardization vary between brands. The most common side effects are allergic skin rash, diarrhea, and upset stomach.

Liver damage appears very rare—when evaluated, this extract was possibly connected in only 4 of 28 reported cases; in most others, other causes were to blame. Importantly, the safety data advises against use during pregnancy and while breastfeeding, so talk with your doctor or pharmacist if either applies to you.

Side effects, ingredient by ingredient Umckaloabo

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Umckaloabo.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 241 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take immunosuppressant drugs (such as cyclosporine or tacrolimus after an organ transplant), this extract may reduce their effectiveness—a Moderate concern. If you're on blood thinners or antiplatelet drugs like warfarin, aspirin, or clopidogrel, there's a Minor risk of increased bleeding.

Check your exact medications with our tool before starting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Umckaloabo may help with acute bronchitis or COPD symptoms. If you take immune-suppressing drugs or blood thinners, check with us first.

Otherwise, it's worth discussing with your pharmacist before starting, especially if you're pregnant or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 29, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Umckaloabo, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700014315
Net contents 2 Fluid Ounce(s); 59.2 mL
Market status On market
Date entered into DSLD Dec 29, 2014
DSLD ID 40073
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Umckaloabo by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
40 Drop(s)
Maximum serving Sizes:
40 Drop(s)
UPC/BARCODE
090700014315
IngredientAmount% DV
Umckaloabo liquid extract0 NP--

Other ingredients: certified organic grain Alcohol, distilled Water, Vegetable Glycerine, Umckaloabo extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

001

General Statements

To assure optimal extraction of Umckaloabo's bioactive compounds, the roots are hand-harvested, carefully shade-dried and are then thoroughly extracted.

Sustainably Cultivated Root

Supports Healthy Sinus, Nasal & Bronchial Function*

LIQUID HERBAL EXTRACT

Suggested/Recommended/Usage/Directions

SUGGESTED USE Shake Well Before Using Two to four times per day take 30 to 40 drops in a little water.

Precautions

Keep Out of the Reach of Children

FDA Disclaimer Statement

THIS STATEMENT HAS NOT BEEN EVALUATED BY THE FDA. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

Formulation

We prepare our Umckaloabo Extract from the root of Pelargonium sidoides plants, which are Certified Organically Grown without the use of chemical fertilizers, pesticides or herbicides.

We prepare our Umckaloabo Extract from the root of Pelargonium sidoides plants, which are Certified Organically Grown without the use of chemical fertilizers, pesticides or herbicides.

FDA Statement of Identity

HERBAL SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Umckaloabo by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Umckaloabo label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Umckaloabo by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size40 Drop(s) Dosage formLiquid Amounts shown are per serving.

Umckaloabo liquid extract

Interacts with
241 drugs
0 NP per serving

Umckaloabo is a root extract from a South African geranium that is most studied for short-term relief of acute bronchitis and other respiratory infect...

Umckaloabo liquid extract monograph & interactions

Other (inactive) ingredients: Certified organic grain Alcohol, Distilled Water, Vegetable Glycerine, Umckaloabo extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Umckaloabo by Herb Pharm Drug Interactions

Want to check YOUR meds against Umckaloabo?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
241Drugs
121 Moderate 120 Minor

Ingredients driving the most interactions

Umckaloabo liquid extract 241

Individual Drug Interactions

The ingredients in Umckaloabo interact with 241 drugs. Click any drug to see the details.

1 of the 1 ingredient in Umckaloabo interact with drugs. Each result below shows which ingredient is responsible. Umckaloabo liquid extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Umckaloabo with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Umckaloabo liquid extract2 drug types · 241 drugs

Immunosuppressants

Theoretically, Pelargonium sidoides might decrease the effectiveness of immunosuppressant therapy.
In vitro research suggests that Pelargonium sidoides has immunostimulant effects.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, Pelargonium sidoides might increase the risk of bleeding when taken with anticoagulant and antiplatelet drugs.
Pelargonium sidoides contains coumarin, which may reduce platelet aggregation. However, in animal models, Pelargonium sidoides extract does not appear to inhibit coagulation or interact with warfarin. This interaction has not been documented in humans.

Likelihood Unlikely Evidence D
Umckaloabo liquid extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Umckaloabo, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Umckaloabo by Herb Pharm: Common Questions

Does Umckaloabo by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Umckaloabo has a known interaction with 241 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Umckaloabo contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Umckaloabo actually work?
For acute bronchitis, the evidence rates it as possibly effective. It's also possibly effective for COPD. For sore throat, we don't have enough reliable evidence to say either way. Talk to your doctor if symptoms don't improve.
What are the most common side effects?
The usual ones are allergic skin rash, diarrhea, and stomach upset. Most people tolerate it well for short-term use.
Can I take this while pregnant or breastfeeding?
No. The safety data advises against it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about safer options.
Can Umckaloabo damage my liver?
Liver damage is very rare. When 28 cases were reviewed, liver injury was possibly linked to this extract in only 4; in most others, other causes were found or ruled out. It does not appear to cause hepatotoxicity in general.
What is Umckaloabo?
It's an extract of Pelargonium sidoides, a plant root traditionally used in South Africa for respiratory health. This is the liquid form, made with organic grain alcohol, water, and glycerine.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Umckaloabo label
Go deeper

The Full Monographs Behind Umckaloabo’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Umckaloabo

Interacts with 241 drugs

Umckaloabo is a root extract from a South African geranium that is most studied for short-term relief of acute bronchitis and other respiratory infections. Some clinical research suggests it...

Read the full Umckaloabo monograph →
Sources

Sources & How We Checked

Umckaloabo's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Umckaloabo 16 references
  1. Chuchalin AG, Berman B, Lehmacher W. Treatment of acute bronchitis in adults with a pelargonium sidoides preparation (EPs 7630): A randomized, double-blind, placebo-controlled trial. Explore 2005;1:437-45. PubMed
  2. Kolodziej H, Kayser O, Radtke OA, et al. Pharmacological profile of extracts of Pelargonium sidoides and their constituents. Phytomedicine 2003;10 Suppl 4:18-24. PubMed
  3. Bereznoy VV, Riley DS, Wassmer G, Heger M. Efficacy of extract of Pelargonium sidoides in children with acute non-group A beta-hemolytic streptococcus tonsillopharyngitis: a randomized, double-blind, placebo-controlled trial. Altern Ther Health Med 2003;9
  4. Kolodziej H, Kiderlen AF. In vitro evaluation of antibacterial and immunomodulatory activities of Pelargonium reniforme, Pelargonium sidoides and the related herbal drug preparation EPs 7630. Phytomedicine 2007;14 Suppl 6:18-26. PubMed
  5. Koch E, Biber A. Treatment of rats with the Pelargonium sidoides extract EPs 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin. Phytomedicine 2007;14 Suppl 6:40-5. PubMed
  6. Conrad A, Hansmann C, Engels I, et al. Extract of Pelargonium sidoides (EPs 7630) improves phagocytosis, oxidative burst, and intracellular killing of human peripheral blood phagocytes in vitro. Phytomedicine 2007;14 Suppl 6:46-51. PubMed
  7. Matthys H, Kamin W, Funk P, Heger M. Pelargonium sidoides preparation (EPs 7630) in the treatment of acute bronchitis in adults and children. Phytomedicine 2007;14 Suppl 6:69-73. PubMed
  8. Conrad A, Jung I, Tioua D, et al. Extract of Pelargonium sidoides (EPs 7630) inhibits the interactions of group A-streptococci and host epithelia in vitro. Phytomedicine 2007;14 Suppl 6:52-9. PubMed
  9. Matthys, H., Eisebitt, R., Seith, B., and Heger, M. Efficacy and safety of an extract of Pelargonium sidoides (EPs 7630) in adults with acute bronchitis. A randomised, double-blind, placebo-controlled trial. Phytomedicine 2003;10 Suppl 4:7-17. PubMed
  10. de Boer, H. J., Hagemann, U., Bate, J., and Meyboom, R. H. Allergic reactions to medicines derived from Pelargonium species. Drug Saf 2007;30(8):677-680. PubMed
  11. Teschke R, Frenzel C, Schulze J, Eickhoff A. Spontaneous reports of primarily suspected herbal hepatotoxicity by Pelargonium sidoides: was causality adequately ascertained? Regul Toxicol Pharmacol 2012;63(1):1-9. PubMed
  12. Teschke R, Frenzel C, Wolff A, et al. Initially purported hepatotoxicity by Pelargonium sidoides: the dilemma of pharmacovigilance and proposals for improvement. Ann Hepatol 2012;11(4):500-12. DOI
  13. Riley DS, Lizogub VG, Zimmermann A, Funk P, Lehmacher W. Efficacy and tolerability of high-dose Pelargonium extract in patients with the common cold. Altern Ther Health Med 2018;24(2):16-26.
  14. Matthys H, Pliskevich DA, Bondarchuk OM, Malek FA, Tribanek M, Kieser M. Randomised, double-blind, placebo-controlled trial of EPs 7630 in adults with COPD. Respir Med 2013;107(5):691-701. PubMed
  15. Willcox M, Simpson C, Wilding S, et al. Pelargonium sidoides root extract for the treatment of acute cough due to lower respiratory tract infection in adults: a feasibility double-blind, placebo-controlled randomised trial. BMC Complement Med Ther 2021;21 PubMed
  16. Kamin W, Behre U, Helm K, Reling B, Funk P, Malek FA. Safety of Pelargonium extract EPs 7630 in young children with acute bronchitis. Front Pediatr 2023;11:1107984. PubMed

See these in context on the Umckaloabo monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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