Fluconazole Injection

Generic name: Pronounced as (floo kon' na zole)
Brand names
  • Diflucan®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 12/15/2015

Fluconazole injection is used to treat fungal infections, including yeast infections of the mouth, throat, esophagus (tube leading from the mouth to the stomach), abdomen (area between the chest and waist), lungs, blood, and other organs. Fluconazole is also used to treat meningitis (infection of the membranes covering the brain and spine) caused by fungus. Fluconazole is also used to prevent yeast infections in patients who are likely to become infected because they are being treated with chemotherapy or radiation therapy before a bone marrow transplant (replacement of unhealthy spongy tissue inside the bones with healthy tissue). Fluconazole is in a class of antifungals called triazoles. It works by slowing the growth of fungi that cause infection.

Fluconazole injection comes as a solution (liquid) to be given through a needle or catheter placed in your vein. It is usually infused (injected slowly) intravenously (into a vein) over a period of 1 to 2 hours, usually once a day for up to 14 days. The length of your treatment depends on your condition and on how well you respond to fluconazole injection. Your doctor will tell you how long to use fluconazole injection.

Your doctor may tell you to use a higher dose of fluconazole injection on the first day of your treatment. Follow these directions carefully.

You may receive fluconazole injection in a hospital or you may use the medication at home. If you are using fluconazole injection at home, use it at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or other health care provider to explain any part you do not understand. Use fluconazole injection exactly as directed. Do not infuse it more quickly than directed, and do not use more or less of it, or use it more often than prescribed by your doctor.

If you will be using fluconazole injection at home, your health care provider will show you how to infuse the medication. Be sure that you understand these directions, and ask your health care provider if you have any questions. Ask your health care provider what to do if you have any problems infusing fluconazole injection.

Before you administer fluconazole, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.

You should begin to feel better during the first few days of treatment with fluconazole injection. If your symptoms do not improve or get worse, call your doctor.

Use fluconazole injection until your doctor tells you that you should stop, even if you feel better. If you stop using fluconazole injection too soon, your infection may come back after a short time.

Fluconazole injection is also sometimes used to treat serious fungal infections that begin in the lungs and can spread through the body and fungal infections of the eye, prostate (a male reproductive organ), skin and nails. Fluconazole injection is also sometimes used to prevent fungal infections in people who are likely to become infected because they have human immunodeficiency virus (HIV) or cancer or have had a transplant operation (surgery to remove an organ and replace it with a donor or artificial organ). Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before receiving fluconazole injection,

  • tell your doctor and pharmacist if you are allergic to fluconazole, other antifungal medications such as itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), or voriconazole (Vfend), any other medications, or any of the ingredients in fluconazole injection. Ask your pharmacist for a list of the ingredients.

  • tell your doctor if you are taking astemizole (Hismanal) (not available in the US), cisapride (Propulsid) (not available in the US),erythromycin (E.E.S., E-Mycin, Erythrocin); pimozide (Orap), quinidine (Quinidex), or terfenadine (Seldane) (not available in the US).Your doctor will probably tell you not to receive fluconazole injection if you are taking any of these medications.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking, or plan to take. Also you should tell your doctor you have used fluconazole injection before starting to take any new medications within 7 days of receiving fluconazole. Be sure to mention any of the following: amitriptyline; amphotericin B (Abelcet, AmBisome, Amphotec, Fungizone); anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); benzodiazepines such as midazolam (Versed); calcium channel blockers such as amlodipine (Norvasc, in Caduet, in Lotrel), felodipine (Plendil, in Lexxel), isradipine (DynaCirc), and nifedipine (Adalat, Procardia); carbamazepine (Carbatrol, Epitol, Tegretol); celecoxib (Celebrex); cholesterol-lowering medications (statins) such as atorvastatin (Lipitor, in Caduet), fluvastatin (Lescol), and simvastatin (Zocor, in Simcor, in Vytorin); clopidogrel (Plavix); cyclophosphamide (Cytoxan); cyclosporine (Gengraf, Neoral, Sandimmune); diuretics ('water pills') such as hydrochlorothiazide (HydroDIURIL, Microzide); fentanyl (Actiq, Duragesic, Fentora, Sublimaze); isoniazid (INH, Nydrazid); losartan (Cozaar, in Hyzaar); methadone (Methadose); nevirapine (Viramune); nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Anaprox, Naprelan); oral contraceptives (birth control pills); oral medication for diabetes such as glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glycron, others), and tolbutamide (Orinase); nortriptyline (Pamelor); phenytoin (Dilantin, Phenytek); prednisone (Sterapred); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); saquinavir (Invirase); sirolimus (Rapamune); tacrolimus (Prograf); theophylline (Elixophyllin, Theo-24, Uniphyl, others); tofacitinib (Xeljanz); triazolam (Halcion); valproic acid (Depakene, Depakote); vinblastine; vincristine; vitamin A; voriconazole (Vfend); and zidovudine (Retrovir). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with fluconazole injection, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have or have ever had cancer; acquired immunodeficiency syndrome (AIDS); an irregular heartbeat; a low level of calcium, sodium, magnesium, or potassium in your blood; or heart, kidney, or liver disease.

  • tell your doctor if you are pregnant, especially if you are in the first 3 months of your pregnancy, plan to become pregnant, or are breast-feeding. If you become pregnant while receiving fluconazole injection, call your doctor. Fluconazole injection may harm the fetus.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are using fluconazole injection.

  • you should know that fluconazole injection may make you dizzy or cause seizures. Do not drive a car or operate machinery until you know how this medication affects you.

Unless your doctor tells you otherwise, continue your normal diet.

Infuse the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not infuse a double dose to make up for a missed one.

  • Fluconazole injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • headache

    • dizziness

    • diarrhea

    • stomach pain

    • heartburn

    • change in ability to taste food

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency treatment:

    • nausea

    • vomiting

    • extreme tiredness

    • unusual bruising or bleeding

    • lack of energy

    • loss of appetite

    • pain in the upper right part of the stomach

    • yellowing of the skin or eyes

    • flu-like symptoms

    • dark urine

    • pale stools

    • seizures

    • rash

    • skin peeling

    • hives

    • itching

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

    • difficulty breathing or swallowing

  • Fluconazole injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Your healthcare provider will tell you how to store your medication. Store your medication only as directed. Make sure you understand how to store your medication properly.

Keep your supplies in a clean, dry place out of the reach of children when you are not using them. Your health care provider will tell you how to dispose of used needles, syringes, tubing, and containers to avoid accidental injury.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • hallucinations (seeing things or hearing voices that do not exist)

  • extreme fear that others are trying to harm you

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to fluconazole injection.

Do not let anyone else use your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the fluconazole injection, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Moxifloxacin.
Repaglinide Repaglinide The risk or severity of hypoglycemia can be increased when Repaglinide is combined with Fluconazole.
Montelukast Montelukast The metabolism of Montelukast can be decreased when combined with Fluconazole.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Insulin glargine is combined with Fluconazole.
Leflunomide Leflunomide The metabolism of Leflunomide can be decreased when combined with Fluconazole.
Nevirapine Nevirapine The serum concentration of Nevirapine can be increased when it is combined with Fluconazole.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Fluconazole.
Dolasetron Dolasetron The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Dolasetron.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Fluconazole.
Anagrelide Anagrelide The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Anagrelide.
Candesartan Candesartan The metabolism of Candesartan can be decreased when combined with Fluconazole.
Cilostazol Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Fluconazole.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Fluconazole.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole Fluconazole may increase the QTc-prolonging and arrhythmogenic activities of Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Fluconazole may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Fluconazole.
Guanfacine Guanfacine Fluconazole may decrease the excretion rate of Guanfacine which could result in a higher serum level.
Magnesium Hydroxide Magnesium Hydroxide Fluconazole may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Miglitol Miglitol The risk or severity of hypoglycemia can be increased when Miglitol is combined with Fluconazole.
Mycophenolate Mycophenolate Fluconazole may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Olsalazine Olsalazine Olsalazine may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Paregoric Paregoric The serum concentration of Morphine can be increased when it is combined with Fluconazole.
Penbutolol Penbutolol The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Acebutolol.
Potassium Potassium Potassium may increase the excretion rate of Fluconazole which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone The serum concentration of Prednisone can be increased when it is combined with Fluconazole.
Ranitidine Ranitidine Fluconazole can cause a decrease in the absorption of Ranitidine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Reserpine Reserpine Fluconazole may decrease the excretion rate of Reserpine which could result in a higher serum level.
Rizatriptan Rizatriptan Fluconazole may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Sumatriptan Sumatriptan Fluconazole may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Fluconazole.
Tizanidine Tizanidine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Tizanidine.
Triamcinolone Triamcinolone The metabolism of Triamcinolone can be decreased when combined with Fluconazole.
Ampicillin Injection Ampicillin Injection Fluconazole may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Fluconazole may decrease the excretion rate of Doxycycline which could result in a higher serum level.
Famotidine Injection Famotidine Injection Famotidine can cause a decrease in the absorption of Fluconazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Fluconazole.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Levofloxacin.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be decreased when combined with Fluconazole.
Metoclopramide Injection Metoclopramide Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Metoclopramide.
Metronidazole Injection Metronidazole Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Metronidazole.
Morphine Injection Morphine Injection The serum concentration of Morphine can be increased when it is combined with Fluconazole.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Fluconazole may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Fluconazole.
Altretamine Altretamine Amphetamine may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Cyclosporine Cyclosporine The serum concentration of Cyclosporine can be increased when it is combined with Fluconazole.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Fluconazole.
Enoxaparin Injection Enoxaparin Injection The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Enoxaparin.
Granisetron Granisetron The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Granisetron.
Torsemide Torsemide The metabolism of Torasemide can be decreased when combined with Fluconazole.
Olanzapine Olanzapine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Olanzapine.
Alosetron Alosetron The metabolism of Alosetron can be decreased when combined with Fluconazole.
Dofetilide Dofetilide The metabolism of Dofetilide can be decreased when combined with Fluconazole.
Eprosartan Eprosartan The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Eprosartan.
Hydroxychloroquine Hydroxychloroquine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Hydroxychloroquine.
Meloxicam Meloxicam The metabolism of Meloxicam can be decreased when combined with Fluconazole.
Pantoprazole Pantoprazole The metabolism of Pantoprazole can be decreased when combined with Fluconazole.
Telmisartan Telmisartan The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Telmisartan.
Temozolomide Temozolomide Fluconazole may decrease the excretion rate of Temozolomide which could result in a higher serum level.
Zaleplon Zaleplon Fluconazole may decrease the excretion rate of Zaleplon which could result in a higher serum level.
Desloratadine Desloratadine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Desloratadine.
Trimipramine Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Fluconazole.
Perindopril Perindopril The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Perindopril.
Tenofovir Tenofovir Tenofovir may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Sirolimus Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Fluconazole.
Dutasteride Dutasteride The metabolism of Dutasteride can be decreased when combined with Fluconazole.
Eplerenone Eplerenone The metabolism of Eplerenone can be decreased when combined with Fluconazole.
Escitalopram Escitalopram The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Escitalopram.
Olmesartan Olmesartan The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Olmesartan.
Zonisamide Zonisamide The metabolism of Zonisamide can be decreased when combined with Fluconazole.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Fluconazole.
Atomoxetine Atomoxetine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Atomoxetine.
Atazanavir Atazanavir The metabolism of Atazanavir can be decreased when combined with Fluconazole.
Almotriptan Almotriptan Fluconazole may decrease the excretion rate of Almotriptan which could result in a higher serum level.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Fluconazole.
Mefloquine Mefloquine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Fluconazole can be decreased when combined with Rosuvastatin.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Fluconazole.
Alfuzosin Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Fluconazole.
Aprepitant Aprepitant The metabolism of Aprepitant can be decreased when combined with Fluconazole.
Emtricitabine Emtricitabine Fluconazole may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine Memantine Fluconazole may decrease the excretion rate of Memantine which could result in a higher serum level.
Tegaserod Tegaserod The serum concentration of Tegaserod can be increased when it is combined with Fluconazole.
Tadalafil Tadalafil Fluconazole may decrease the excretion rate of Tadalafil which could result in a higher serum level.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Gemifloxacin.
Progesterone Progesterone The metabolism of Progesterone can be decreased when combined with Fluconazole.
Apomorphine Injection Apomorphine Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Apomorphine.
Protriptyline Protriptyline The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Protriptyline.
Rifaximin Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Fluconazole.
Duloxetine Duloxetine The metabolism of Duloxetine can be decreased when combined with Fluconazole.
Norethindrone Norethindrone The bioavailability of Norethisterone can be increased when combined with Fluconazole.
Tinidazole Tinidazole Fluconazole may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Bosentan Bosentan The metabolism of Bosentan can be decreased when combined with Fluconazole.
Cefditoren Cefditoren Fluconazole may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Cyanocobalamin Injection Cyanocobalamin Injection Fluconazole may decrease the excretion rate of Hydroxocobalamin which could result in a higher serum level.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Fluconazole.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Fluconazole.
Ganciclovir Ganciclovir Fluconazole may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Insulin aspart is combined with Fluconazole.
Ribavirin Ribavirin Fluconazole may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Solifenacin Solifenacin The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Solifenacin.
Valganciclovir Valganciclovir Fluconazole may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Voriconazole Voriconazole The metabolism of Voriconazole can be decreased when combined with Fluconazole.
Adefovir Adefovir Adefovir may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine Amphetamine may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Pramlintide Injection Pramlintide Injection The risk or severity of hypoglycemia can be increased when Pramlintide is combined with Fluconazole.
Exenatide Injection Exenatide Injection The risk or severity of hypoglycemia can be increased when Exenatide is combined with Fluconazole.
Ibandronate Ibandronate The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Ibandronate.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Fluconazole.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Fluconazole.
Pregabalin Pregabalin The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Pregabalin.
Tipranavir Tipranavir The serum concentration of Tipranavir can be increased when it is combined with Fluconazole.
Felbamate Felbamate The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Felbamate.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Insulin detemir is combined with Fluconazole.
Ranolazine Ranolazine The metabolism of Ranolazine can be decreased when combined with Fluconazole.
Rasagiline Rasagiline Fluconazole may decrease the excretion rate of Rasagiline which could result in a higher serum level.
Imatinib Imatinib The metabolism of Imatinib can be decreased when combined with Fluconazole.
Sitagliptin Sitagliptin The risk or severity of hypoglycemia can be increased when Sitagliptin is combined with Fluconazole.
Varenicline Varenicline Fluconazole may decrease the excretion rate of Varenicline which could result in a higher serum level.
Gefitinib Gefitinib The metabolism of Gefitinib can be decreased when combined with Fluconazole.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Salbutamol.
Paliperidone Paliperidone The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Paliperidone.
Bortezomib Bortezomib The metabolism of Bortezomib can be decreased when combined with Fluconazole.
Clofarabine Injection Clofarabine Injection Fluconazole may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Insulin glulisine is combined with Fluconazole.
Lubiprostone Lubiprostone Fluconazole may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Oxaliplatin.
Posaconazole Posaconazole The serum concentration of Posaconazole can be increased when it is combined with Fluconazole.
Primaquine Primaquine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Primaquine.
Aliskiren Aliskiren The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Aliskiren.
Pemetrexed Injection Pemetrexed Injection Fluconazole may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Dimenhydrinate Dimenhydrinate The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Dimenhydrinate.
Retapamulin Retapamulin The metabolism of Retapamulin can be decreased when combined with Fluconazole.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Vorinostat.
Sorafenib Sorafenib The metabolism of Sorafenib can be decreased when combined with Fluconazole.
Sunitinib Sunitinib The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Fluconazole.
Dronabinol Dronabinol The metabolism of Dronabinol can be decreased when combined with Fluconazole.
Lapatinib Lapatinib The metabolism of Lapatinib can be decreased when combined with Fluconazole.
Levocetirizine Levocetirizine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Levocetirizine.
Pegaptanib Injection Pegaptanib Injection Fluconazole may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Fluconazole.
Azacitidine Injection Azacitidine Injection Fluconazole may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Temsirolimus Temsirolimus The serum concentration of Temsirolimus can be increased when it is combined with Fluconazole.
Lenalidomide Lenalidomide Fluconazole may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
Nilotinib Nilotinib The metabolism of Nilotinib can be decreased when combined with Fluconazole.
Toremifene Toremifene The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Toremifene.
Bexarotene Bexarotene The metabolism of Bexarotene can be decreased when combined with Fluconazole.
Budesonide Budesonide Fluconazole may decrease the excretion rate of Budesonide which could result in a higher serum level.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Doripenem Injection Doripenem Injection Fluconazole may decrease the excretion rate of Doripenem which could result in a higher serum level.
Etravirine Etravirine The metabolism of Etravirine can be decreased when combined with Fluconazole.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Arsenic trioxide.
Desvenlafaxine Desvenlafaxine Fluconazole may decrease the excretion rate of Desvenlafaxine which could result in a higher serum level.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Fluconazole.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Fluconazole.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Fluconazole.
Flecainide Flecainide The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Flecainide.
Certolizumab Injection Certolizumab Injection Fluconazole may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Fluconazole.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Fluconazole.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Fluconazole.
Methylnaltrexone Injection Methylnaltrexone Injection Fluconazole may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Rufinamide Rufinamide The metabolism of Rufinamide can be decreased when combined with Fluconazole.
Silodosin Silodosin The serum concentration of Silodosin can be increased when it is combined with Fluconazole.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Fluconazole.
Dexrazoxane Injection Dexrazoxane Injection Fluconazole may decrease the excretion rate of Dexrazoxane which could result in a higher serum level.
Milnacipran Milnacipran Fluconazole may decrease the excretion rate of Milnacipran which could result in a higher serum level.
Dexlansoprazole Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Fluconazole.
Plerixafor Injection Plerixafor Injection Fluconazole may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Sodium Phosphate Sodium Phosphate Sodium phosphate, monobasic may increase the hyperkalemic activities of Fluconazole.
Fesoterodine Fesoterodine Fluconazole may decrease the excretion rate of Fesoterodine which could result in a higher serum level.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Degarelix.
Betaxolol Betaxolol The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Betaxolol.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Fluconazole.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Fluconazole.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Fluconazole.
Everolimus Everolimus The metabolism of Everolimus can be decreased when combined with Fluconazole.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be increased when it is combined with Fluconazole.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Fluconazole.
Pralatrexate Injection Pralatrexate Injection Fluconazole may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection Fluconazole may decrease the excretion rate of Palonosetron which could result in a higher serum level.
Saxagliptin Saxagliptin The risk or severity of hypoglycemia can be increased when Saxagliptin is combined with Fluconazole.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Telavancin.
Romidepsin Injection Romidepsin Injection The serum concentration of Romidepsin can be increased when it is combined with Fluconazole.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Fluconazole.
Topotecan Topotecan The serum concentration of Topotecan can be increased when it is combined with Fluconazole.
Pazopanib Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Fluconazole.
Asenapine Asenapine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Asenapine.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Fluconazole.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Fluconazole.
Levonorgestrel Levonorgestrel The bioavailability of Levonorgestrel can be increased when combined with Fluconazole.
Liraglutide Injection Liraglutide Injection The risk or severity of hypoglycemia can be increased when Liraglutide is combined with Fluconazole.
Dalfampridine Dalfampridine Fluconazole may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The serum concentration of Cabazitaxel can be increased when it is combined with Fluconazole.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Lurasidone Lurasidone The metabolism of Lurasidone can be decreased when combined with Fluconazole.
Acetaminophen Injection Acetaminophen Injection Fluconazole may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Fluconazole.
Ipilimumab Injection Ipilimumab Injection Fluconazole may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Terbutaline.
Azilsartan Azilsartan The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Azilsartan medoxomil.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be decreased when combined with Fluconazole.
Roflumilast Roflumilast The metabolism of Roflumilast can be decreased when combined with Fluconazole.
Linagliptin Linagliptin The risk or severity of hypoglycemia can be increased when Linagliptin is combined with Fluconazole.
Rilpivirine Rilpivirine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Rilpivirine.
Telaprevir Telaprevir The serum concentration of Glecaprevir can be increased when it is combined with Fluconazole.
Potassium Iodide Potassium Iodide Potassium Iodide may increase the hyperkalemic activities of Fluconazole.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Fluconazole.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Triptorelin.
Rivaroxaban Rivaroxaban The serum concentration of Rivaroxaban can be increased when it is combined with Fluconazole.
Ticagrelor Ticagrelor The serum concentration of Ticagrelor can be increased when it is combined with Fluconazole.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Fluconazole.
Ruxolitinib Ruxolitinib The serum concentration of Ruxolitinib can be increased when it is combined with Fluconazole.
Vandetanib Vandetanib The metabolism of Vandetanib can be decreased when combined with Fluconazole.
Clobazam Clobazam The serum concentration of Clobazam can be increased when it is combined with Fluconazole.
Vemurafenib Vemurafenib The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Vismodegib can be decreased when combined with Fluconazole.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Fluconazole.
Deferiprone Deferiprone Fluconazole may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Fluconazole.
Crizotinib Crizotinib The serum concentration of Crizotinib can be increased when it is combined with Fluconazole.
Cabergoline Cabergoline The metabolism of Cabergoline can be decreased when combined with Fluconazole.
Naloxone Injection Naloxone Injection Fluconazole may decrease the excretion rate of Naloxone which could result in a higher serum level.
Ambrisentan Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Fluconazole.
Fondaparinux Injection Fondaparinux Injection Fluconazole may decrease the excretion rate of Fondaparinux which could result in a higher serum level.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Carfilzomib can be increased when it is combined with Fluconazole.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be decreased when combined with Fluconazole.
Mirabegron Mirabegron The serum concentration of Mirabegron can be increased when it is combined with Fluconazole.
Regorafenib Regorafenib The serum concentration of Regorafenib can be increased when it is combined with Fluconazole.
Bosutinib Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Fluconazole.
Lorcaserin Lorcaserin The risk or severity of hypoglycemia can be increased when Mecasermin is combined with Fluconazole.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Fluconazole.
Teduglutide Injection Teduglutide Injection Fluconazole may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Bedaquiline Bedaquiline The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Bedaquiline.
Tofacitinib Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Fluconazole.
Alogliptin Alogliptin The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Fluconazole.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Fluconazole.
Pomalidomide Pomalidomide The serum concentration of Pomalidomide can be increased when it is combined with Fluconazole.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The serum concentration of Trastuzumab emtansine can be increased when it is combined with Fluconazole.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Fluconazole.
Canagliflozin Canagliflozin The risk or severity of hypoglycemia can be increased when Canagliflozin is combined with Fluconazole.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Fluconazole which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib Dabrafenib The serum concentration of Dabrafenib can be increased when it is combined with Fluconazole.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Fluconazole.
Trametinib Trametinib Fluconazole may decrease the excretion rate of Trametinib which could result in a higher serum level.
Dolutegravir Dolutegravir The serum concentration of Dolutegravir can be increased when it is combined with Fluconazole.
Afatinib Afatinib The serum concentration of Afatinib can be increased when it is combined with Fluconazole.
Levomilnacipran Levomilnacipran Fluconazole may decrease the excretion rate of Levomilnacipran which could result in a higher serum level.
Ertapenem Injection Ertapenem Injection Fluconazole may decrease the excretion rate of Ertapenem which could result in a higher serum level.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Fluconazole.
Perampanel Perampanel The metabolism of Perampanel can be decreased when combined with Fluconazole.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Fluconazole.
Lomitapide Lomitapide The metabolism of Lomitapide can be decreased when combined with Fluconazole.
Avanafil Avanafil The metabolism of Avanafil can be decreased when combined with Fluconazole.
Ketorolac Injection Ketorolac Injection The metabolism of Fluconazole can be decreased when combined with Ketorolac.
Simeprevir Simeprevir The serum concentration of Simeprevir can be increased when it is combined with Fluconazole.
Sofosbuvir Sofosbuvir The serum concentration of Sofosbuvir can be increased when it is combined with Fluconazole.
Dapagliflozin Dapagliflozin The risk or severity of hypoglycemia can be increased when Dapagliflozin is combined with Fluconazole.
Apremilast Apremilast Fluconazole may decrease the excretion rate of Apremilast which could result in a higher serum level.
Droxidopa Droxidopa Fluconazole may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Ceritinib Ceritinib The serum concentration of Ceritinib can be increased when it is combined with Fluconazole.
Albiglutide Injection Albiglutide Injection The risk or severity of hypoglycemia can be increased when Albiglutide is combined with Fluconazole.
Belinostat Injection Belinostat Injection The serum concentration of Belinostat can be increased when it is combined with Fluconazole.
Idelalisib Idelalisib The metabolism of Idelalisib can be decreased when combined with Fluconazole.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be decreased when combined with Fluconazole.
Empagliflozin Empagliflozin The risk or severity of hypoglycemia can be increased when Empagliflozin is combined with Fluconazole.
Vorapaxar Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Fluconazole.
Suvorexant Suvorexant The metabolism of Suvorexant can be decreased when combined with Fluconazole.
Dulaglutide Injection Dulaglutide Injection The risk or severity of hypoglycemia can be increased when Dulaglutide is combined with Fluconazole.
Edoxaban Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Fluconazole.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Fluconazole.
Methamphetamine Methamphetamine Fluconazole may decrease the excretion rate of Metamfetamine which could result in a higher serum level.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Fluconazole.
Nintedanib Nintedanib The serum concentration of Nintedanib can be increased when it is combined with Fluconazole.
Risperidone Injection Risperidone Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Risperidone.
Palbociclib Palbociclib The metabolism of Palbociclib can be decreased when combined with Fluconazole.
Insulin Human Inhalation Insulin Human Inhalation The risk or severity of hypoglycemia can be increased when Insulin human is combined with Fluconazole.
Lenvatinib Lenvatinib The serum concentration of Lenvatinib can be increased when it is combined with Fluconazole.
Naloxegol Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Fluconazole.
Panobinostat Panobinostat The metabolism of Panobinostat can be decreased when combined with Fluconazole.
Haloperidol Injection Haloperidol Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Haloperidol.
Ivabradine Ivabradine The metabolism of Ivabradine can be decreased when combined with Fluconazole.
Amiloride Amiloride Fluconazole may increase the excretion rate of Amiloride which could result in a lower serum level and potentially a reduction in efficacy.
Macitentan Macitentan Fluconazole may decrease the excretion rate of Macitentan which could result in a higher serum level.
Sonidegib Sonidegib The metabolism of Sonidegib can be decreased when combined with Fluconazole.
Flibanserin Flibanserin The metabolism of Flibanserin can be decreased when combined with Fluconazole.
Prednisolone Prednisolone The serum concentration of Prednisolone can be increased when it is combined with Fluconazole.
Daclatasvir Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Fluconazole.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Fluconazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Ziprasidone.
Penicillin G Procaine Injection Penicillin G Procaine Injection Fluconazole may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Insulin degludec is combined with Fluconazole.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Fluconazole.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Fluconazole.
Osimertinib Osimertinib The serum concentration of Osimertinib can be increased when it is combined with Fluconazole.
Alectinib Alectinib The metabolism of Alectinib can be decreased when combined with Fluconazole.
Ixazomib Ixazomib The metabolism of Ixazomib can be decreased when combined with Fluconazole.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Fluconazole.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The therapeutic efficacy of Amphotericin B can be decreased when used in combination with Fluconazole.
Dexamethasone Injection Dexamethasone Injection The metabolism of Dexamethasone can be decreased when combined with Fluconazole.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Fluconazole.
Venetoclax Venetoclax The metabolism of Venetoclax can be decreased when combined with Fluconazole.
Cobicistat Cobicistat The metabolism of Cobicistat can be decreased when combined with Fluconazole.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Fluconazole.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Fluconazole.
Furosemide Injection Furosemide Injection Fluconazole may increase the excretion rate of Furosemide which could result in a lower serum level and potentially a reduction in efficacy.
Rucaparib Rucaparib The serum concentration of Rucaparib can be increased when it is combined with Fluconazole.
Lixisenatide Injection Lixisenatide Injection The risk or severity of hypoglycemia can be increased when Lixisenatide is combined with Fluconazole.
Ribociclib Ribociclib The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Ribociclib.
Brigatinib Brigatinib The metabolism of Brigatinib can be decreased when combined with Fluconazole.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Fluconazole.
Deutetrabenazine Deutetrabenazine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Deutetrabenazine.
Valbenazine Valbenazine Fluconazole may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Deflazacort Deflazacort The serum concentration of Deflazacort can be increased when it is combined with Fluconazole.
Naldemedine Naldemedine Fluconazole may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Midostaurin Midostaurin The metabolism of Midostaurin can be decreased when combined with Fluconazole.
Neratinib Neratinib The metabolism of Neratinib can be decreased when combined with Fluconazole.
Enasidenib Enasidenib The metabolism of Enasidenib can be decreased when combined with Fluconazole.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Fluconazole.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be decreased when combined with Fluconazole.
Benznidazole Benznidazole Fluconazole may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Copanlisib Injection Copanlisib Injection The serum concentration of Copanlisib can be increased when it is combined with Fluconazole.
Delafloxacin Delafloxacin The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Delafloxacin.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Fluconazole.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Fluconazole.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be decreased when combined with Fluconazole.
Semaglutide Injection Semaglutide Injection The risk or severity of hypoglycemia can be increased when Semaglutide is combined with Fluconazole.
Tetrabenazine Tetrabenazine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Tetrabenazine.
Ertugliflozin Ertugliflozin The risk or severity of hypoglycemia can be increased when Ertugliflozin is combined with Fluconazole.
Buprenorphine Injection Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Fluconazole.
Apalutamide Apalutamide Fluconazole may decrease the excretion rate of Apalutamide which could result in a higher serum level.
Avatrombopag Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Fluconazole.
Baricitinib Baricitinib The metabolism of Baricitinib can be decreased when combined with Fluconazole.
Lofexidine Lofexidine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Lofexidine.
Plazomicin Injection Plazomicin Injection Fluconazole may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Fluconazole.
Encorafenib Encorafenib The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Encorafenib.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Fluconazole.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be decreased when combined with Fluconazole.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Fluconazole.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Fluconazole.
Doravirine Doravirine The metabolism of Doravirine can be decreased when combined with Fluconazole.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Fluconazole.
Dacomitinib Dacomitinib The serum concentration of Dacomitinib can be increased when it is combined with Fluconazole.
Duvelisib Duvelisib The serum concentration of Duvelisib can be increased when it is combined with Fluconazole.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Fluconazole.
Stiripentol Stiripentol Fluconazole may decrease the excretion rate of Stiripentol which could result in a higher serum level.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Fluconazole.
Gilteritinib Gilteritinib The serum concentration of Gilteritinib can be increased when it is combined with Fluconazole.
Glasdegib Glasdegib The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Glasdegib.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Fluconazole.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Fluconazole.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Fluconazole.
Rifamycin Rifamycin The serum concentration of Rifamycin can be increased when it is combined with Fluconazole.
Prucalopride Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Fluconazole.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Fluconazole is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Fluconazole.
Esomeprazole Injection Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Fluconazole.
Alpelisib Alpelisib The metabolism of Alpelisib can be decreased when combined with Fluconazole.
Solriamfetol Solriamfetol Fluconazole may decrease the excretion rate of Solriamfetol which could result in a higher serum level.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Fluconazole.
Triclabendazole Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Fluconazole.
Entrectinib Entrectinib The metabolism of Entrectinib can be decreased when combined with Fluconazole.
Pexidartinib Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Fluconazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Fluconazole.
Pitolisant Pitolisant Fluconazole may increase the QTc-prolonging activities of Pitolisant.
Pretomanid Pretomanid The serum concentration of Pretomanid can be increased when it is combined with Fluconazole.
Fedratinib Fedratinib The serum concentration of Fedratinib can be increased when it is combined with Fluconazole.
Lefamulin Lefamulin Fluconazole may increase the QTc-prolonging activities of Lefamulin.
Phenytoin Injection Phenytoin Injection The serum concentration of Phenytoin can be increased when it is combined with Fluconazole.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Fosphenytoin can be increased when it is combined with Fluconazole.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Fluconazole.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Fluconazole.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Fluconazole.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Fluconazole.
Lumateperone Lumateperone The serum concentration of Lumateperone can be increased when it is combined with Fluconazole.
Lasmiditan Lasmiditan The serum concentration of Lasmiditan can be increased when it is combined with Fluconazole.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Fluconazole.
Tazemetostat Tazemetostat The serum concentration of Tazemetostat can be increased when it is combined with Fluconazole.
Cenobamate Cenobamate The metabolism of Cenobamate can be decreased when combined with Fluconazole.
Pemigatinib Pemigatinib The metabolism of Pemigatinib can be decreased when combined with Fluconazole.
Selumetinib Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Fluconazole.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Fluconazole.
Tucatinib Tucatinib The serum concentration of Tucatinib can be increased when it is combined with Fluconazole.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Fluconazole.
Ripretinib Ripretinib The serum concentration of Ripretinib can be increased when it is combined with Fluconazole.
Lemborexant Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Fluconazole.
Fostemsavir Fostemsavir The serum concentration of Fostemsavir can be increased when it is combined with Fluconazole.
Lurbinectedin Injection Lurbinectedin Injection The serum concentration of Lurbinectedin can be increased when it is combined with Fluconazole.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Fluconazole.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Fluconazole.
Pralsetinib Pralsetinib The serum concentration of Pralsetinib can be increased when it is combined with Fluconazole.
Relugolix Relugolix The serum concentration of Relugolix can be increased when it is combined with Fluconazole.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The bioavailability of Drospirenone can be increased when combined with Fluconazole.
Viloxazine Viloxazine Fluconazole may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Theophylline Theophylline The serum concentration of Theophylline can be increased when it is combined with Fluconazole.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Indomethacin Indomethacin The metabolism of Indomethacin can be decreased when combined with Fluconazole.
Mefenamic Acid Mefenamic Acid The metabolism of Mefenamic acid can be decreased when combined with Fluconazole.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Fluconazole.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Trazodone Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Fluconazole.
Isotretinoin Isotretinoin Fluconazole may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate Sucralfate Sucralfate can cause a decrease in the absorption of Fluconazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Floxuridine Floxuridine Fluconazole may decrease the excretion rate of Floxuridine which could result in a higher serum level.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Fluconazole.
Metaxalone Metaxalone Fluconazole may decrease the excretion rate of Metaxalone which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection The metabolism of Fluconazole can be decreased when combined with Methotrexate.
Primidone Primidone The metabolism of Primidone can be decreased when combined with Fluconazole.
Methsuximide Methsuximide The metabolism of Methsuximide can be decreased when combined with Fluconazole.
Chlorpromazine Chlorpromazine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Chlorpromazine.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Fluconazole.
Oxazepam Oxazepam Fluconazole may decrease the excretion rate of Oxazepam which could result in a higher serum level.
Flurazepam Flurazepam Fluconazole may decrease the excretion rate of Flurazepam which could result in a higher serum level.
Clorazepate Clorazepate Fluconazole may decrease the excretion rate of Clorazepic acid which could result in a higher serum level.
Lorazepam Lorazepam The metabolism of Fluconazole can be decreased when combined with Lorazepam.
Carmustine Carmustine Fluconazole may decrease the excretion rate of Carmustine which could result in a higher serum level.
Amantadine Amantadine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Amantadine.
Codeine Codeine Fluconazole may decrease the excretion rate of Codeine which could result in a higher serum level.
Bromocriptine Bromocriptine The risk or severity of hypoglycemia can be increased when Bromocriptine is combined with Fluconazole.
Phenelzine Phenelzine Fluconazole may decrease the excretion rate of Phenelzine which could result in a higher serum level.
Tetracycline Tetracycline Fluconazole may decrease the excretion rate of Tetracycline which could result in a higher serum level.
Prochlorperazine Prochlorperazine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Prochlorperazine.
Thioridazine Thioridazine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Thioridazine.
Bleomycin Bleomycin Fluconazole may decrease the excretion rate of Bleomycin which could result in a higher serum level.
Dapsone Dapsone The metabolism of Dapsone can be decreased when combined with Fluconazole.
Sulfadiazine Sulfadiazine The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Fluconazole.
Oxycodone Oxycodone The metabolism of Oxycodone can be decreased when combined with Fluconazole.
Methadone Methadone The metabolism of Methadone can be decreased when combined with Fluconazole.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Fluconazole.
Benztropine Benztropine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Benzatropine.
Maprotiline Maprotiline The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Maprotiline.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Fluconazole.
Orphenadrine Orphenadrine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Orphenadrine.
Azathioprine Azathioprine Fluconazole may decrease the excretion rate of Azathioprine which could result in a higher serum level.
Phentermine Phentermine The metabolism of Phentermine can be decreased when combined with Fluconazole.
Methylphenidate Methylphenidate Fluconazole may decrease the excretion rate of Methylphenidate which could result in a higher serum level.
Amoxapine Amoxapine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Amoxapine.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Hydrocortisone Hydrocortisone The metabolism of Hydrocortisone can be decreased when combined with Fluconazole.
Doxorubicin Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Fluconazole.
Dactinomycin Dactinomycin The serum concentration of Dactinomycin can be increased when it is combined with Fluconazole.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Fluconazole.
Methyldopa Methyldopa Fluconazole may decrease the excretion rate of Methyldopa which could result in a higher serum level.
Clonidine Clonidine The metabolism of Clonidine can be decreased when combined with Fluconazole.
Hydralazine Hydralazine Fluconazole may decrease the excretion rate of Hydralazine which could result in a higher serum level.
Cimetidine Cimetidine The bioavailability of Fluconazole can be decreased when combined with Cimetidine.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Warfarin Warfarin The therapeutic efficacy of Warfarin can be increased when used in combination with Fluconazole.
Clonazepam Clonazepam Fluconazole may decrease the excretion rate of Clonazepam which could result in a higher serum level.
Loperamide Loperamide The serum concentration of Loperamide can be increased when it is combined with Fluconazole.
Promethazine Promethazine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Promethazine.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin The risk or severity of adverse effects can be increased when Nitrofurantoin is combined with Fluconazole.
Digoxin Digoxin Fluconazole may decrease the excretion rate of Digoxin which could result in a higher serum level.
Chloroquine Chloroquine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Chloroquine.
Quinine Quinine The risk or severity of hypoglycemia can be increased when Quinine is combined with Fluconazole.
Ethosuximide Ethosuximide The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Ethosuximide.
Triamterene Triamterene Fluconazole may decrease the excretion rate of Triamterene which could result in a higher serum level.
Chlorothiazide Chlorothiazide Chlorothiazide may increase the excretion rate of Fluconazole which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone Chlorthalidone Chlorthalidone may increase the excretion rate of Fluconazole which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone Metolazone Fluconazole may increase the excretion rate of Metolazone which could result in a lower serum level and potentially a reduction in efficacy.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Fluconazole which could result in a lower serum level and potentially a reduction in efficacy.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Fluconazole.
Secobarbital Secobarbital Fluconazole may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Desipramine Desipramine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Desipramine.
Amitriptyline Amitriptyline Amitriptyline may increase the QTc-prolonging activities of Fluconazole.
Imipramine Imipramine The serum concentration of Imipramine can be increased when it is combined with Fluconazole.
Probenecid Probenecid Fluconazole may decrease the excretion rate of Probenecid which could result in a higher serum level.
Quinidine Quinidine The serum concentration of Quinidine can be increased when it is combined with Fluconazole.
Procainamide Procainamide Fluconazole may decrease the excretion rate of Procainamide which could result in a higher serum level.
Isoniazid Isoniazid Fluconazole may decrease the excretion rate of Isoniazid which could result in a higher serum level.
Pyrazinamide Pyrazinamide Fluconazole may decrease the excretion rate of Pyrazinamide which could result in a higher serum level.
Rifampin Rifampin Rifampicin may increase the excretion rate of Fluconazole which could result in a lower serum level and potentially a reduction in efficacy.
Disopyramide Disopyramide The risk or severity of hypoglycemia can be increased when Disopyramide is combined with Fluconazole.
Valproic Acid Valproic Acid The metabolism of Valproic acid can be decreased when combined with Fluconazole.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Fluconazole.
Butabarbital Butabarbital Fluconazole may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Liothyronine Liothyronine Fluconazole may decrease the excretion rate of Liothyronine which could result in a higher serum level.
Methimazole Methimazole Fluconazole may decrease the excretion rate of Methimazole which could result in a higher serum level.
Chlorpropamide Chlorpropamide The serum concentration of Chlorpropamide can be increased when it is combined with Fluconazole.
Tolbutamide Tolbutamide The serum concentration of Tolbutamide can be increased when it is combined with Fluconazole.
Tolazamide Tolazamide The serum concentration of Tolazamide can be increased when it is combined with Fluconazole.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Fluconazole.
Baclofen Baclofen Baclofen may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Doxylamine Doxylamine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Doxylamine.
Cyproheptadine Cyproheptadine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Cyproheptadine.
Clemastine Clemastine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Clemastine.
Chlorpheniramine Chlorpheniramine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Dexbrompheniramine.
Ethambutol Ethambutol Fluconazole may decrease the excretion rate of Ethambutol which could result in a higher serum level.
Methyclothiazide Methyclothiazide Methyclothiazide may increase the excretion rate of Fluconazole which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide Hydrochlorothiazide The serum concentration of Fluconazole can be increased when it is combined with Hydrochlorothiazide.
Dantrolene Dantrolene The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone Fluconazole may decrease the excretion rate of Chlorzoxazone which could result in a higher serum level.
Carisoprodol Carisoprodol The metabolism of Carisoprodol can be decreased when combined with Fluconazole.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Disulfiram Disulfiram The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Disulfiram.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Fluconazole.
Nortriptyline Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Fluconazole.
Spironolactone Spironolactone Fluconazole may increase the excretion rate of Spironolactone which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection The therapeutic efficacy of Amphotericin B can be decreased when used in combination with Fluconazole.
Phytonadione Phytonadione Fluconazole may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Nadolol Nadolol Fluconazole may decrease the excretion rate of Nadolol which could result in a higher serum level.
Allopurinol Allopurinol Fluconazole may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Fluconazole.
Clomiphene Clomiphene The serum concentration of Clomifene can be increased when it is combined with Fluconazole.
Flavoxate Flavoxate Fluconazole may decrease the excretion rate of Flavoxate which could result in a higher serum level.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Papaverine.
Fluorouracil Injection Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Fluorouracil.
Colchicine Colchicine The metabolism of Colchicine can be decreased when combined with Fluconazole.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Dacarbazine Dacarbazine Fluconazole may decrease the excretion rate of Dacarbazine which could result in a higher serum level.
Acetazolamide Acetazolamide Acetazolamide may increase the excretion rate of Fluconazole which could result in a lower serum level and potentially a reduction in efficacy.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Ketoconazole Ketoconazole The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Ketoconazole.
Pyrantel Pyrantel Fluconazole may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Fluconazole.
Vincristine Injection Vincristine Injection The excretion of Vincristine can be decreased when combined with Fluconazole.
Captopril Captopril The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Captopril.
Vinblastine Vinblastine The metabolism of Vinblastine can be decreased when combined with Fluconazole.
Ethacrynic Acid Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Metoprolol Metoprolol The metabolism of Metoprolol can be decreased when combined with Fluconazole.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Hydroxyzine.
Thiothixene Thiothixene The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Thiothixene.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Fluconazole.
Salsalate Salsalate Salsalate may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Alprazolam Alprazolam The metabolism of Alprazolam can be decreased when combined with Fluconazole.
Temazepam Temazepam Fluconazole may decrease the excretion rate of Temazepam which could result in a higher serum level.
Triazolam Triazolam The metabolism of Triazolam can be decreased when combined with Fluconazole.
Dicyclomine Dicyclomine Fluconazole may decrease the excretion rate of Dicyclomine which could result in a higher serum level.
Hyoscyamine Hyoscyamine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Hyoscyamine.
Propantheline Propantheline Fluconazole may decrease the excretion rate of Propantheline which could result in a higher serum level.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Fluconazole.
Diltiazem Diltiazem The metabolism of Diltiazem can be decreased when combined with Fluconazole.
Nifedipine Nifedipine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Nifedipine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Fluconazole.
Verapamil Verapamil The metabolism of Verapamil can be decreased when combined with Fluconazole.
Atenolol Atenolol The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Atenolol.
Pindolol Pindolol The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Pindolol.
Cisplatin Injection Cisplatin Injection Fluconazole may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal Diflunisal may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Piroxicam Piroxicam The metabolism of Piroxicam can be decreased when combined with Fluconazole.
Bumetanide Bumetanide Fluconazole may increase the excretion rate of Bumetanide which could result in a lower serum level and potentially a reduction in efficacy.
Etoposide Etoposide The serum concentration of Etoposide can be increased when it is combined with Fluconazole.
Glyburide Glyburide The serum concentration of Glyburide can be increased when it is combined with Fluconazole.
Glipizide Glipizide The serum concentration of Glipizide can be increased when it is combined with Fluconazole.
Indapamide Indapamide Fluconazole may increase the excretion rate of Indapamide which could result in a lower serum level and potentially a reduction in efficacy.
Amoxicillin Amoxicillin Fluconazole may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Fluconazole may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline Pentoxifylline Fluconazole may decrease the excretion rate of Pentoxifylline which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection The risk or severity of hypoglycemia can be increased when Pentamidine is combined with Fluconazole.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Labetalol Labetalol The metabolism of Labetalol can be decreased when combined with Fluconazole.
Auranofin Auranofin Fluconazole may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Leuprolide.
Gemfibrozil Gemfibrozil Fluconazole may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Ketoprofen Ketoprofen Fluconazole may decrease the excretion rate of Ketoprofen which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Pimozide Pimozide The serum concentration of Pimozide can be increased when it is combined with Fluconazole.
Enalapril Enalapril The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Enalapril.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Fluconazole.
Amiodarone Amiodarone The metabolism of Amiodarone can be decreased when combined with Fluconazole.
Aztreonam Injection Aztreonam Injection Fluconazole may decrease the excretion rate of Aztreonam which could result in a higher serum level.
Buspirone Buspirone Fluconazole may decrease the excretion rate of Buspirone which could result in a higher serum level.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Fluconazole.
Ciprofloxacin Ciprofloxacin The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Ciprofloxacin.
Mesalamine Mesalamine Mesalazine may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Fluconazole.
Fluoxetine Fluoxetine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Fluoxetine.
Nimodipine Nimodipine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Nimodipine.
Clozapine Clozapine The metabolism of Clozapine can be decreased when combined with Fluconazole.
Estazolam Estazolam Fluconazole may decrease the excretion rate of Estazolam which could result in a higher serum level.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Fluconazole.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Ofloxacin.
Didanosine Didanosine Didanosine can cause a decrease in the absorption of Fluconazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pentostatin Injection Pentostatin Injection Fluconazole may decrease the excretion rate of Pentostatin which could result in a higher serum level.
Clarithromycin Clarithromycin The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Clarithromycin.
Benazepril Benazepril The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Benazepril.
Etodolac Etodolac The metabolism of Etodolac can be decreased when combined with Fluconazole.
Felodipine Felodipine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Felodipine.
Fosinopril Fosinopril The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Fosinopril.
Nabumetone Nabumetone The metabolism of Nabumetone can be decreased when combined with Fluconazole.
Pravastatin Pravastatin The serum concentration of Pravastatin can be increased when it is combined with Fluconazole.
Quinapril Quinapril The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Quinapril.
Ramipril Ramipril The risk or severity of hyperkalemia can be increased when Ramipril is combined with Fluconazole.
Simvastatin Simvastatin The metabolism of Simvastatin can be decreased when combined with Fluconazole.
Amlodipine Amlodipine The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Amlodipine.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be decreased when combined with Fluconazole.
Itraconazole Itraconazole The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Itraconazole.
Lisinopril Lisinopril The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Lisinopril.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Sotalol Sotalol The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Sotalol.
Bisoprolol Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Fluconazole.
Zolpidem Zolpidem The metabolism of Zolpidem can be decreased when combined with Fluconazole.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Fluconazole.
Isradipine Isradipine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Isradipine.
Omeprazole Omeprazole The metabolism of Omeprazole can be decreased when combined with Fluconazole.
Cisapride Cisapride The metabolism of Cisapride can be decreased when combined with Fluconazole.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Fluconazole.
Venlafaxine Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Fluconazole.
Nizatidine Nizatidine Nizatidine can cause a decrease in the absorption of Fluconazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Famciclovir Famciclovir The metabolism of Famciclovir can be decreased when combined with Fluconazole.
Fluvoxamine Fluvoxamine Fluvoxamine may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Nefazodone Nefazodone Fluconazole may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Lamotrigine Lamotrigine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Lamotrigine.
Losartan Losartan The serum concentration of E3174, an active metabolite of Losartan, can be decreased when used in combination with Fluconazole.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Fluconazole.
Vinorelbine Injection Vinorelbine Injection The metabolism of Vinorelbine can be decreased when combined with Fluconazole.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Moexipril.
Lansoprazole Lansoprazole The metabolism of Lansoprazole can be decreased when combined with Fluconazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Fluconazole.
Nicardipine Nicardipine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Nicardipine.
Bupropion Bupropion The metabolism of Bupropion can be decreased when combined with Fluconazole.
Ticlopidine Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Fluconazole.
Saquinavir Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Fluconazole.
Metformin Metformin The risk or severity of hypoglycemia can be increased when Metformin is combined with Fluconazole.
Dalteparin Injection Dalteparin Injection The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Dalteparin.
Nisoldipine Nisoldipine The metabolism of Nisoldipine can be decreased when combined with Fluconazole.
Lamivudine Lamivudine Fluconazole may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Acarbose Acarbose The risk or severity of hypoglycemia can be increased when Acarbose is combined with Fluconazole.
Glimepiride Glimepiride The serum concentration of Glimepiride can be increased when it is combined with Fluconazole.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Fluconazole.
Indinavir Indinavir The metabolism of Indinavir can be decreased when combined with Fluconazole.
Ritonavir Ritonavir The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Fluconazole.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Meropenem Injection Meropenem Injection Fluconazole may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Fluconazole.
Zafirlukast Zafirlukast The metabolism of Zafirlukast can be decreased when combined with Fluconazole.
Fosfomycin Fosfomycin Fluconazole may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Mirtazapine Mirtazapine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Mirtazapine.
Trandolapril Trandolapril The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Trandolapril.
Topiramate Topiramate Fluconazole may decrease the excretion rate of Topiramate which could result in a higher serum level.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Fluconazole.
Valsartan Valsartan The metabolism of Valsartan can be decreased when combined with Fluconazole.
Insulin Lispro Injection Insulin Lispro Injection The risk or severity of hypoglycemia can be increased when Insulin lispro is combined with Fluconazole.
Pramipexole Pramipexole Fluconazole may decrease the excretion rate of Pramipexole which could result in a higher serum level.
Donepezil Donepezil The metabolism of Donepezil can be decreased when combined with Fluconazole.
Nelfinavir Nelfinavir The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Nelfinavir.
Fexofenadine Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Fluconazole.
Azithromycin Azithromycin The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Azithromycin.
Carvedilol Carvedilol The metabolism of Carvedilol can be decreased when combined with Fluconazole.
Nilutamide Nilutamide Fluconazole may decrease the excretion rate of Nilutamide which could result in a higher serum level.
Flutamide Flutamide Fluconazole may decrease the excretion rate of Flutamide which could result in a higher serum level.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Fluconazole.
Bicalutamide Bicalutamide The metabolism of Bicalutamide can be decreased when combined with Fluconazole.
Sertraline Sertraline The metabolism of Sertraline can be decreased when combined with Fluconazole.
Propafenone Propafenone The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Propafenone.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Fluconazole.
Tamsulosin Tamsulosin Fluconazole may decrease the excretion rate of Tamsulosin which could result in a higher serum level.
Finasteride Finasteride The metabolism of Finasteride can be decreased when combined with Fluconazole.
Quetiapine Quetiapine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Quetiapine.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Cetirizine Cetirizine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Cetirizine.
Paroxetine Paroxetine The metabolism of Paroxetine can be decreased when combined with Fluconazole.
Tolcapone Tolcapone Fluconazole may decrease the excretion rate of Tolcapone which could result in a higher serum level.
Citalopram Citalopram The risk or severity of QTc prolongation and serotonin syndrome can be increased when Fluconazole is combined with Citalopram.
Capecitabine Capecitabine The metabolism of Capecitabine can be decreased when combined with Fluconazole.
Efavirenz Efavirenz The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Efavirenz.
Abacavir Abacavir Fluconazole may decrease the excretion rate of Abacavir which could result in a higher serum level.
Sildenafil Sildenafil The serum concentration of Sildenafil can be increased when it is combined with Fluconazole.
Pioglitazone Pioglitazone The risk or severity of hypoglycemia can be increased when Pioglitazone is combined with Fluconazole.
Celecoxib Celecoxib The metabolism of Celecoxib can be decreased when combined with Fluconazole.
Rosiglitazone Rosiglitazone The risk or severity of hypoglycemia can be increased when Rosiglitazone is combined with Fluconazole.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Fluconazole.
Thalidomide Thalidomide The metabolism of Thalidomide can be decreased when combined with Fluconazole.
Oseltamivir Oseltamivir Fluconazole may decrease the excretion rate of Oseltamivir which could result in a higher serum level.
Balsalazide Balsalazide Balsalazide may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Nateglinide Nateglinide The risk or severity of hypoglycemia can be increased when Nateglinide is combined with Fluconazole.
Galantamine Galantamine The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Galantamine.
Rabeprazole Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Fluconazole.
Terbinafine Terbinafine The metabolism of Terbinafine can be decreased when combined with Fluconazole.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists