Captopril
231 interactions 998 cited referencesCaptopril is an ACE inhibitor used to treat high blood pressure, heart failure, and certain kidney and heart conditions. Read the full Captopril drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Captopril Relugolix Orgovyx Increased relugolix exposure Details Captopril Allopurinol Aloprim Hypersensitivity reactions (Stevens-Johnson syndrome, skin eruptions) Details Captopril Allopurinol Injection Aloprim Hypersensitivity reactions (Stevens-Johnson syndrome, skin eruptions) Details Captopril Aspirin Acuprin® Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Captopril Aspirin Rectal Aspirin Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Captopril Azathioprine Azasan An increased risk of myelosuppression and an increased risk of hepatotoxicity Details Captopril Azilsartan Edarbi Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Captopril Alteplase, Recombinant Activase An increased risk of orolingual angioedema Details Captopril Amiloride Increased risk of hyperkalemia Details Captopril Azilsartan Medoxomil Edarbi Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Captopril Candesartan Atacand Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Captopril Canrenoate Increased risk of hyperkalemia Details Captopril Cyclosporine Atopica Acute renal dysfunction, increased risk of hyperkalemia and an increased cycloSPORINE exposure Details Captopril Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Captopril Digoxin Cardoxin® Increased digoxin exposure Details Captopril Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Captopril Doxorubicin Hydrochloride Liposome Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Captopril Ensartinib Increased ensartinib exposure Details Captopril Eplerenone Inspra Increased risk of hyperkalemia Details Captopril Eprosartan Teveten® Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Captopril Everolimus Afinitor Increased risk of angioedema Details Captopril Furosemide Disal An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Captopril Insulin Icodec-Abae Awiqli An increased risk of hypoglycemia Details Captopril Interferon Alfa-2A Hematologic abnormalities (granulocytopenia, thrombocytopenia) Details Captopril Irbesartan Avapro Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Captopril Lefamulin Xenleta Increased lefamulin exposure and an increased risk of lefamulin-related adverse reactions Details Captopril Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Captopril Lithium Increased risk of lithium toxicity Details Captopril Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse effects Details Captopril Losartan Arbli Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Captopril Mavorixafor Xolremdi Increased mavorixafor exposure and an increased risk of mavorixafor-related adverse effects Details Captopril Melphalan Alkeran An increased risk of severe hypotension Details Captopril Mercaptopurine Purinethol® An increased risk of myelosuppression and an increased risk of hepatotoxicity Details Captopril Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Captopril Morphine Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Captopril Morphine Sulfate Liposome Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Captopril Nilotinib Increased exposure of nilotinib Details Captopril Olmesartan Benicar Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Captopril Oxypurinol Hypersensitivity reactions (Stevens-Johnson syndrome, skin eruptions) Details Captopril Pixantrone Increased exposure to pixantrone DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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