Rasagiline

Name: Rasagiline Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

50 interactions 6 explained in plain English

Also sold as: Azilect

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acetaminophen And Codeine Morphine Injection Maprotiline Methylphenidate Methyldopa Deutetrabenazine

10 Contraindicated 31 Major 9 Moderate

All (50) Contraindicated (10) Major (31) Moderate (9)

Contraindicated

Rasagiline Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of serotonin syndrome Details Rasagiline Sertraline Explained An increased risk of serotonin syndrome (hypertension, tachycardia, hyperthermia, myoclonus, mental status changes) or CNS toxicit... Details Rasagiline Deutetrabenazine Austedo Hypertensive crisis (headache, hyperpyrexia, hypertension) Details Rasagiline Diethylpropion Tenuate Hypertensive crisis (headache, hyperpyrexia, hypertension) Details Rasagiline Linezolid Injection Zyvox An increased risk of hypertensive crisis (headache, palpitation, neck stiffness) or seizure Details Rasagiline Maprotiline Ludiomil® An increased risk of severe or life threatening reactions, like neurotoxicity, seizures Details Rasagiline Methyldopa Aldomet® Hypertensive crisis (headache, palpitation, neck stiffness) Details Rasagiline Methylphenidate Adhansia XR® An increased risk of hypertensive crisis (headache, palpitation, and neck stiffness) Details Rasagiline Methylphenidate Transdermal Patch Daytrana An increased risk of hypertensive crisis (headache, palpitation, and neck stiffness) Details Rasagiline Morphine Injection Astramorph® PF Increased risk of the CNS and respiratory depressant effects of morphine and an increased risk of serotonin syndrome Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.