Drug & supplement interaction

Andiroba + Nusinersen Sodium

Nusinersen Sodium brand name: Spinraza.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Andiroba and Nusinersen Sodium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Andiroba and Nusinersen Sodium

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Nusinersen Sodium and Andiroba in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Andiroba safety at a glance

Andiroba overall Use caution Generally used on the skin; safety of taking it internally is not well studied.
Pregnancy Avoid Not enough safety data; best to avoid during pregnancy.
Breastfeeding Avoid Not enough safety data; best to avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Nusinersen Sodium and Andiroba? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Nusinersen Sodium

Interactions in our licensed database are recorded against drug classes, not just single drug names. Nusinersen Sodium is filed under 2 classifications — anticoagulant/antiplatelet drugs, nephrotoxic drugs. Andiroba has documented interactions with 1 drug class — the most serious being anticonvulsants (minor) — and none of Nusinersen Sodium’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Andiroba Does Interact With Other Medications

Andiroba has 50 minor known drug interactions in our database — Nusinersen Sodium isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Andiroba

Covers the 2,830 medications we’ve checked against Andiroba. Pick one to open its full report.

What to actually watch for

What Nusinersen Sodium’s Own FDA Label Lists

This is not an interaction — none of it involves Andiroba. These are the most notable effects listed in the ADVERSE REACTIONS section of Nusinersen Sodium’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 9 of them are worth acting on rather than waiting out — marked below.

  • Low sodium Worth acting on
  • A low platelet count Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • A higher chance of infection Worth acting on mentioned in 4.8% of FDA reports for Nusinersen Sodium
  • Bleeding or bruising Worth acting on
  • An allergic reaction Worth acting on
  • Weight loss

Showing the 10 most notable of 17 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Nusinersen Sodium. Read the label on DailyMed › Where a percentage is shown, it is the share of 7,655 voluntary FDA FAERS reports for Nusinersen Sodium that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Andiroba’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Andiroba side to compare — that is a limit of the record, not a statement that Andiroba has no side effects.

Everything else you take

See Every Supplement That Interacts With Nusinersen Sodium

This page covers Andiroba only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Nusinersen Sodium page lists 208 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Asarabacca (major), Danshen (major), Piracetam (major), Siberian Cocklebur (major) and Aconite (moderate).

By severity: 4 major · 186 moderate · 18 minor.

From our pharmacist’s overview on the Nusinersen Sodium page

“Spinraza (nusinersen) is given by spinal injection to treat spinal muscular atrophy, and it carries its own warnings for low platelets and kidney stress, which makes the 208 supplements on this page worth real vigilance rather than a shrug. All but six of them, 202 ingredients, could raise bleeding risk by thinning the blood or dulling…”

Reviewed by 2 · Jul 18, 2026

Open the Nusinersen Sodium interaction page

How much people look this up

Where Andiroba and Nusinersen Sodium Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Andiroba
Steady interest

#940 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Nusinersen Sodium
Steady interest

#2,437 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Andiroba is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Andiroba reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Andiroba and Nusinersen Sodium records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Andiroba

What is Andiroba?

Andiroba
  • Skin care and wound healing
  • Insect repellent
  • Muscle and joint aches
  • Anti-inflammatory skin conditions
  • Hair and scalp care

Andiroba is an oil pressed from the seeds of an Amazonian tree, used mainly on the skin for inflammation, minor wounds, aches, and as an insect repellent. Most evidence comes from laboratory and animal studies, so its benefits in people are not well proven. It is most often used topically; avoid internal use and use during pregnancy or breastfeeding because safety has not been established.

Carapa guianensis · Meliaceae · Seed oil (mainly), bark, and leaves · Topical oil, skin and hair products, soaps, balms, candles (insect repellent)

An interaction check asks whether these two react with each other — it does not ask whether Andiroba is a good idea for someone in your situation. Here is what our Andiroba record says about it on its own.

Andiroba: dosing

There is no established standard dose for andiroba. Doses have not been confirmed in reliable human studies.For topical products, follow the directions on the label.

From our Andiroba monograph — the full record covers uses, side effects and every documented interaction.

Read the full Andiroba monograph & all interactions
Medication

About Nusinersen Injection

What Is Nusinersen Injection Used For?

Brand name: Spinraza

Spinraza is used to treat spinal muscular atrophy (SMA) in pediatric and adult patients. SMA is a genetic condition caused by a shortage of a protein called SMN.

See full Nusinersen Injection drug information
Keep checking

Other Drugs & Andiroba

Browse every other medication we’ve checked against Andiroba — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
50Minor
2,779No known interaction
Minor

50 interactions

No interaction 2,779 drugs checked — show the list
Evidence & sources

Andiroba References

The 3 sources that drive our Andiroba monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Andiroba is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Carapa guianensis (Andiroba) — U.S. National Library of Medicine (PubChem / NCBI) Source
  2. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  3. Using Dietary Supplements Safely — MedlinePlus (U.S. National Library of Medicine) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Andiroba and Nusinersen Sodium Together: Common Questions

Is it safe to take Andiroba with Nusinersen Sodium?
We do not list a known interaction between Andiroba and Nusinersen Sodium. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Andiroba and Nusinersen Sodium combination checked?
Interactions in our licensed database are recorded against drug classes. Nusinersen Sodium is filed under 2 classifications, and Andiroba has documented interactions with 1 drug class — none of Nusinersen Sodium's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Andiroba interact with any other medications?
Yes. Andiroba has 50 documented drug interactions in our database — Nusinersen Sodium is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Nusinersen Sodium interact with any supplements?
Yes. Nusinersen Sodium has documented interactions with 208 supplements in our database — Andiroba is not one of them. The Nusinersen Sodium interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Nusinersen Sodium and Andiroba?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.