Drug & supplement interaction

Bay Leaf + Naloxone

Naloxone brand names: Narcan, Zimhi, Rivive.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Bay Leaf and Naloxone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Bay Leaf and Naloxone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Naloxone and Bay Leaf in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Bay Leaf safety at a glance

Bay Leaf overall Use caution Safe as a food seasoning, but concentrated supplements and essential oil are less studied.
Pregnancy Use caution Food amounts are likely fine, but avoid medicinal or large amounts due to limited safety data.
Breastfeeding Use caution Food amounts are likely fine, but avoid medicinal doses because safety is not well studied.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Naloxone and Bay Leaf? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Naloxone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Naloxone is filed under a single classification. Bay Leaf has documented interactions with 3 drug classes — the most serious being antidiabetes drugs (moderate), cns depressants (moderate) and narcotic drugs (moderate) — and none of Naloxone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Bay Leaf Does Interact With Other Medications

Bay Leaf has 335 moderate known drug interactions in our database — Naloxone isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Bay Leaf

Covers the 2,830 medications we’ve checked against Bay Leaf. Pick one to open its full report.

What to actually watch for

What Bay Leaf Itself Has Been Linked To

This is not an interaction — nothing below involves Naloxone. It is the side-effect record for Bay Leaf on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Bay Leaf, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • Wheezing Worth acting on Additional detail

    “Inhalation of bay leaf may cause occupational asthma, as confirmed by several challenges.”

    Bay Leaf · Natural Medicines adverse-effect record, reported in asthma.

    1 source cited
    1. 783. Cartier LC, Lehrer A, Malo JL. Occupational asthma caused by aromatic herbs. Allergy 1996;51:647-9. DOI
  • An allergic reaction Worth acting on Additional detail

    “Orally, bay leaf is well tolerated when used in amounts found in foods and seems to be well tolerated when the leaf powder is used as medicine. However, the whole, intact leaf can cause severe adverse effects.”

    Bay Leaf · Natural Medicines adverse-effect record, reported in dermatitis.

    “Bay leaf can cause allergic reactions, including contact dermatitis. In one case, allergic contact dermatitis occurred with a positive skin test after use of a massage oil containing bay leaf. Another patient developed erythematous plaques on the elbow after applying bay leaves with a topical occlusion for 2 days. The dermatitis resolved after a two-week course of topical corticosteroids.”

    Bay Leaf · Natural Medicines adverse-effect record, reported in dermatitis.

    4 sources cited
    1. 15571. Adisen E, Onder M. Allergic contact dermatitis from Laurus nobilis oil induced by massage. Contact Dermatitis 2007;56:360-1.
    2. 33791. Ozden, M. G., Oztas, P., Oztas, M. O., and Onder, M. Allergic contact dermatitis from Laurus nobilis (laurel) oil. Contact Dermatitis 2001;45(3):178. PubMed
    3. 33864. Cheminat, A., Stampf, J. L., and Benezra, C. Allergic contact dermatitis to laurel (Laurus nobilis L.): isolation and identification of haptens. Arch Dermatol Res 1984;276(3):178-181. PubMed
    4. 104767. Vassileva S, Darlenski R. Bay leaf phytodermatitis. Contact Dermatitis. 2020 Nov 15. PubMed
  • A skin rash Additional detail

    Recorded for Bay Leaf in the same Natural Medicines adverse-effect record shown under An allergic reaction above.

Everything above comes from the Natural Medicines adverse-effect record for Bay Leaf — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Naloxone’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Naloxone column appears here.

Everything else you take

See Every Supplement That Interacts With Naloxone

This page covers Bay Leaf only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Naloxone page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (moderate), Gamma Butyrolactone (gbl) (moderate) and Gamma-hydroxybutyrate (ghb) (moderate).

By severity: 3 moderate.

From our pharmacist’s overview on the Naloxone page

“The list of supplements that interact with naloxone, the emergency spray or injection (Narcan, Zimhi, Rivive) that reverses opioid overdoses, is short and unusual. All three entries are forms of the same substance: gamma-hydroxybutyrate (GHB) and two chemicals the body converts into it, GBL and 1,4-butanediol.”

Reviewed by 2 · Jul 18, 2026

Open the Naloxone interaction page

How much people look this up

Where Bay Leaf and Naloxone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Bay Leaf
Top 25%

#342 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Naloxone
Top half

#727 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Bay Leaf reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Bay Leaf and Naloxone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Bay Leaf

What is Bay Leaf?

Bay Leaf
  • Cooking and flavoring
  • Digestive upset
  • Blood sugar support
  • Colds and congestion
  • Joint and muscle discomfort

Bay leaf is a common culinary herb that is safe in the small amounts used in cooking. Some people take it for digestion, blood sugar, or colds, but strong human evidence for these uses is lacking. Talk to your pharmacist or doctor before using concentrated supplements or essential oils.

Laurus nobilis · Lauraceae · Leaves and essential oil · Whole or ground dried leaves, tea, capsules, extracts, essential oil

An interaction check asks whether these two react with each other — it does not ask whether Bay Leaf is a good idea for someone in your situation. Here is what our Bay Leaf record says about it on its own.

Bay Leaf: dosing

There is no standardized or proven medicinal dose for bay leaf. In cooking, one or two whole leaves are typically added during simmering and then removed before serving.For teas, extracts, and capsules, follow the directions on the product label, since strength varies widely between products.

From our Bay Leaf monograph — the full record covers uses, side effects and every documented interaction.

Read the full Bay Leaf monograph & all interactions
Medication

About Naloxone Injection

What Is Naloxone Injection Used For?

Brand names: Narcan, Zimhi, Rivive

Naloxone Hydrochloride injection is used for the emergency treatment of known or suspected opioid overdose — reversing dangerous slowing of breathing and loss of consciousness caused by opioids. It is also approved for use in pediatric patients of all ages.

Naloxone Hydrochloride injection is additionally indicated specifically for military personnel and chemical incident responders: for emergency treatment of patients 12 and older where high-potency opioids such as fentanyl analogues have been used as a chemical weapon, and for temporary protection against breathing and nervous system depression when entering an area contaminated with such opioids. Zimhi (naloxone HCl) is a pre-filled, single-dose injectable product approved for intramuscular or subcutaneous use in known or suspected opioid overdose.

See full Naloxone Injection drug information
Keep checking

Other Drugs & Bay Leaf

Browse every other medication we’ve checked against Bay Leaf — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
335Moderate
0Minor
2,494No known interaction
Moderate

335 interactions

Showing 60 of 335 moderate interactions — see all 335 on the Bay Leaf page.

No interaction 2,494 drugs checked — show the list
Evidence & sources

Bay Leaf References

The 7 references that drive our Bay Leaf monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Cartier LC, Lehrer A, Malo JL. Occupational asthma caused by aromatic herbs. Allergy 1996;51:647-9. DOI
  3. Adisen E, Onder M. Allergic contact dermatitis from Laurus nobilis oil induced by massage. Contact Dermatitis 2007;56:360-1.
  4. Ozden, M. G., Oztas, P., Oztas, M. O., and Onder, M. Allergic contact dermatitis from Laurus nobilis (laurel) oil. Contact Dermatitis 2001;45(3):178. PubMed
  5. Khan, A., Zaman, G., and Anderson, R. A. Bay leaves improve glucose and lipid profile of people with type 2 diabetes. J Clin Biochem.Nutr. 2009;44(1):52-56. PubMed
  6. Cheminat, A., Stampf, J. L., and Benezra, C. Allergic contact dermatitis to laurel (Laurus nobilis L.): isolation and identification of haptens. Arch Dermatol Res 1984;276(3):178-181. PubMed
  7. Vassileva S, Darlenski R. Bay leaf phytodermatitis. Contact Dermatitis. 2020 Nov 15. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Bay Leaf and Naloxone Together: Common Questions

Is it safe to take Bay Leaf with Naloxone?
We do not list a known interaction between Bay Leaf and Naloxone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Bay Leaf and Naloxone combination checked?
Interactions in our licensed database are recorded against drug classes. Naloxone is filed under 1 classification, and Bay Leaf has documented interactions with 3 drug classes — none of Naloxone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Bay Leaf interact with any other medications?
Yes. Bay Leaf has 335 documented drug interactions in our database — Naloxone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Naloxone interact with any supplements?
Yes. Naloxone has documented interactions with 3 supplements in our database — Bay Leaf is not one of them. The Naloxone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Naloxone and Bay Leaf?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.