Black Tea + Warfarin Sodium
Warfarin Sodium brand names: Coumadin, Panwarfin, Sofarin.
Warfarin Sodium falls into 2 drug categories that Black Tea can interact with; the most serious is rated moderate. Theoretically, black tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full interaction reportBlack Tea and Warfarin Sodium
These two interact in 2 distinct ways. Each one is explained separately below.
Why Are There 2 Interactions?
Black Tea interacts with whole categories of medication. Warfarin Sodium falls into 2 of those categories, so it can interact with Black Tea in 2 different ways. We’ve listed each one below — your overall risk is driven by the most serious of them (Moderate).
ANTICOAGULANT/ANTIPLATELET DRUGS
1 of 2Why this applies to Warfarin Sodium
Warfarin Sodium falls under ANTICOAGULANT/ANTIPLATELET DRUGS — the group Black Tea interacts with.
Black tea contains caffeine. Caffeine is reported to have antiplatelet activity. Theoretically, the caffeine in black tea might increase the risk of bleeding when used concomitantly with antiplatelet drugs. However, this interaction has not been reported in humans.
Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
Here's the short version: there's a theoretical concern that the caffeine in black tea has mild antiplatelet activity, which could add to warfarin's blood-thinning effect and slightly raise your bleeding risk. I want to be honest with you though, this idea comes from lab studies, not from actual reports in people drinking tea, so it's a weak signal.
That said, warfarin is a narrow-therapeutic-index drug, meaning small shifts in either direction can matter. Watch for unusual bruising, nosebleeds, bleeding gums, or blood in your urine or stool. The bigger practical issue is consistency: keep your tea habit steady rather than going from none to many cups a day. Talk with your pharmacist or doctor before making changes, and keep up with your regular INR checks.
- Ali M, Afzal M. A potent inhibitor of thrombin stimulated platelet thromboxane formation from unprocessed tea. Prostaglandins Leukot Med 1987;27:9-13. PubMed
- Ardlie NG, Glew G, Schultz BG, Schwartz CJ. Inhibition and reversal of platelet aggregation by methyl xanthines. Thromb Diath Haemorrh 1967;18:670-3. DOI
- Steptoe, A., Gibson, E. L., Vuononvirta, R., Hamer, M., Wardle, J., Rycroft, J. A., Martin, J. F., and Erusalimsky, J. D. The effects of chronic tea intake on platelet activation and inflammation: a double-blind placebo controlled trial. Atherosclerosis PubMed
WARFARIN (Coumadin)
2 of 2In one case, a 67-year-old female who took warfarin and who regularly consumed large amounts of black tea had a stable international normalized ratio (INR) of 1.7 to 2.7. However, the INR increased to 5 when tea consumption was discontinued. It is thought that the vitamin K content of black tea may have reduced the effects of warfarin. Monitor patients carefully who start or discontinue drinking black tea while taking warfarin.
Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
Here's the gist for warfarin and black tea. Warfarin works by blocking vitamin K, which your body needs to form clots. Black tea contains a little vitamin K, so drinking very large amounts could push back against warfarin and make it work less well, raising your risk of a clot. This isn't about a cup or two a day. The single case we have on file involved someone drinking a lot of tea regularly, and their INR (the blood test that tracks how thin your blood is) jumped when they stopped.
Because warfarin is a narrow therapeutic index drug, even small, steady changes matter. The honest truth is this is weak, anecdotal evidence. The smart move is consistency: keep your tea habit roughly the same, and tell your pharmacist or doctor before any big change.
- Parker DL, Hoffmann TK, Tucker MA, et al. Interaction between warfarin and black tea. Ann Pharmacother 2009;43:150-1. PubMed
What These Ratings Mean
Every interaction above is graded three ways — here’s the key to each label.
Clinically significant. Avoid the combination, or use only under close professional supervision.
Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.
Generally not serious. Be aware of it and mention it to your pharmacist.
- LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
- ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
- UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
- AHigh-quality meta-analysis (quantitative systematic review).
- BCase-control study.
- CConsensus.
- DAnecdotal evidence.
These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.
Black Tea Also Interacts With Other Medications
Black Tea has 8 major, 571 moderate, 114 minor known drug interactions in our database — the Warfarin Sodium one above is among them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Black Tea
We haven’t checked that one against Black Tea yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Black Tea. Pick one to open its full report.
Questions About Black Tea or Warfarin Sodium
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Black Tea or Warfarin Sodium, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Does Ginger Water Interfere With Amoxicillin-Clavulanate? ›
- Can You Take Nattokinase With a 40 mg Statin? ›
- Is Krill Oil Safe To Take With Losartan? ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Warfarin Sodium
This page covers Black Tea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Warfarin Sodium page lists 361 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Alfalfa (major), American Ginseng (major), Beer (major) and Cannabis (major).
Taking Black Tea as Part of a Dietary Supplement Product? Check It for Interactions
We hold 271 real supplement products containing Black Tea, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Black Tea. Your product may carry other ingredients that interact with Warfarin Sodium too, on top of Black Tea — and those would not show on this page. Find your product and we’ll check every ingredient on its label:
Where Black Tea and Warfarin Sodium Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#278 of 1,452 supplements looked up here in the last 7 days
#18 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
About Black Tea
What is Black Tea?
- Mental alertness and energy
- Heart health support
- Blood pressure and cholesterol
- Digestive complaints
- Weight management
- Antioxidant support
Black tea is a popular caffeinated drink made from the fully oxidized leaves of the Camellia sinensis plant, and it contains caffeine and antioxidant plant compounds. Moderate tea drinking is generally safe for most adults and may modestly support heart health and alertness, but it is not a proven treatment for any disease. If you are pregnant, breastfeeding, sensitive to caffeine, or taking medicines, talk to your pharmacist or doctor.
About Warfarin
What Is Warfarin Used For?
Brand names: Coumadin, Panwarfin, Sofarin
Warfarin sodium tablets and Jantoven tablets are both used to prevent and treat venous thrombosis (blood clots in the veins) and pulmonary embolism (a clot in the lungs). They are also used to prevent clot-related complications in people with atrial fibrillation (an irregular heart rhythm) or who have had a heart valve replaced.
In people who have had a heart attack, warfarin is used to reduce the risk of death, another heart attack, stroke, or other clotting events. It does not dissolve an existing clot, but it helps prevent the clot from growing and stops new dangerous clots from forming.
Other Drugs & Black Tea
Browse every other medication we’ve checked against Black Tea — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
8 interactions
- Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate ›
- Ephedrine, Guaifenesin (otc Drug) ›
- Ephedrine, Hydroxyzine, Theophylline ›
- Ephedrine, Phenobarbital, Potassium Iodide, Theophylline ›
- Aminophylline, Amobarbital, Ephedrine ›
- Dyphylline, Ephedrine, Guaifenesin, Phenobarbital ›
- Ephedrine, Guaifenesin, Phenobarbital, Theophylline ›
- Ephedrine, Phenobarbital, Theophylline ›
571 interactions
- Diclofenac Sodium ›
- Diltiazem ›
- Theophylline ›
- Ibuprofen ›
- Salbutamol Sulfate ›
- Phentermine ›
- Aspirin ›
- Methylphenidate ›
- Naproxen ›
- Erythromycin ›
- Estradiol ›
- Minocycline ›
- Hydrochlorothiazide ›
- Norethindrone ›
- Verapamil ›
- Levonorgestrel ›
- Phenylpropanolamine ›
- Glyburide ›
- Ciprofloxacin ›
- Nicotine ›
- Phenytoin ›
- Carbamazepine ›
- Diclofenac Potassium ›
- Dipyridamole ›
- Phenylephrine ›
- Pseudoephedrine ›
- Albuterol ›
- Amphetamine ›
- Conjugated Estrogens ›
- Diethylpropion ›
- Ketoprofen ›
- Methotrexate ›
- Ofloxacin ›
- Rifampin ›
- Selegiline ›
- Terbutaline ›
- Trichlormethiazide ›
- Adenosine (prescription Drug) ›
- Bendroflumethiazide ›
- Bivalirudin ›
- Caffeine (otc Drug) ›
- Cimetidine ›
- Erythromycin Ethylsuccinate ›
- Erythromycin Stearate ›
- Etoposide ›
- Isoniazid ›
- Levofloxacin ›
- Metolazone ›
- Modafinil ›
- Omeprazole ›
- Oxymetazoline Hydrochloride ›
- Paroxetine ›
- Phenobarbital ›
- Riluzole ›
- Spironolactone ›
- Valproic Acid ›
- Acetazolamide ›
- Amiodarone ›
- Amphetamine Sulfate ›
- Bromfenac Sodium ›
Showing 60 of 571 moderate interactions — see all 571 on the Black Tea page.
114 interactions
- Insulin (rdna) ›
- Insulin (pork) ›
- Flurbiprofen ›
- Insulin (human) ›
- Trimipramine ›
- Lofepramine ›
- Nortriptyline ›
- Acarbose ›
- Desipramine ›
- Doxepin ›
- Fluphenazine ›
- Insulin Glargine ›
- Semaglutide ›
- Chlorpromazine ›
- Chlorpropamide ›
- Clomipramine ›
- Exenatide ›
- Fluconazole ›
- Glipizide ›
- Glucagon ›
- Imipramine ›
- Insulin Lispro ›
- Metformin ›
- Prochlorperazine ›
- Repaglinide ›
- Sitagliptin ›
- Tirzepatide ›
- Acepromazine ›
- Acetohexamide ›
- Albiglutide ›
- Alogliptin ›
- Amitriptyline ›
- Amoxapine ›
- Canagliflozin ›
- Carphenazine ›
- Cyamemazine ›
- Dapagliflozin ›
- Dasiglucagon Hydrochloride ›
- Dulaglutide ›
- Empagliflozin ›
- Ertugliflozin ›
- Esketamine ›
- Ethanol ›
- Exenatide Synthetic ›
- Gliclazide ›
- Glimepiride ›
- Glucose ›
- Inhaled Insulin ›
- Insulin ›
- Insulin (bovine) ›
- Insulin Aspart ›
- Insulin Degludec ›
- Insulin Determir ›
- Insulin Glargine (rdna) ›
- Insulin Glargine Recombinant ›
- Insulin Glulisine (rdna) ›
- Insulin Lispro Recombinant ›
- Insulin Lispro-aabc ›
- Linagliptin ›
- Liraglutide ›
Showing 60 of 114 minor interactions — see all 114 on the Black Tea page.
No interaction 2,136 drugs checked — show the list
We also checked Black Tea against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Amlodipine ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Ivermectin ›
- Tadalafil ›
- Acetaminophen ›
- Valacyclovir ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Sumatriptan ›
- Prednisone ›
- Propranolol ›
- Bupropion ›
- Acyclovir ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Gabapentin ›
- Pregabalin ›
- Acetaminophen, Codeine ›
- Isotretinoin ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Methylene Blue ›
- Amlodipine Besylate ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Bisoprolol ›
- Levothyroxine, Liothyronine ›
- Acetaminophen, Oxycodone ›
- Dapsone ›
- Diazepam ›
- Cyclopentolate ›
- Candesartan Cilexetil ›
- Cephalexin ›
- Roxithromycin ›
- Pegunigalsidase Alfa-iwxj ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Daptomycin ›
- Mirtazapine ›
- Finasteride ›
- Hexobarbitone ›
- Valsartan ›
- Levothyroxine Sodium ›
- Levetiracetam ›
- Alprazolam ›
- Amlodipine Besylate, Benazepril ›
- Bromocriptine ›
- Dutasteride ›
- Mitomycin ›
- Minoxidil ›
Showing the 60 most looked-up of 2,136 medications checked with no known interaction — see the full Black Tea list.
Sources & How We Checked
Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Taking Black Tea and Warfarin Sodium Together: Common Questions
Can you take Black Tea with Warfarin Sodium?
Why are there 2 interactions listed for Black Tea and Warfarin Sodium?
How serious is the Black Tea and Warfarin Sodium interaction?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.