Drug & supplement interaction

Schizonepeta + Mineral Oil

Mineral Oil brand name: Kondremul Plain.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Schizonepeta and Mineral Oil in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Mineral Oil states a food rule worth keeping to.

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Interaction report

Schizonepeta and Mineral Oil

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mineral Oil and Schizonepeta in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Schizonepeta safety at a glance

Schizonepeta overall Use caution Generally used in small amounts in traditional formulas, but high-quality safety data in humans are limited.
Pregnancy Avoid Safety in pregnancy has not been established, so it is best avoided.
Breastfeeding Avoid There is not enough information to consider it safe while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mineral Oil and Schizonepeta? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Mineral Oil

Interactions in our licensed database are recorded against drug classes, not just single drug names. Mineral Oil is filed under a single classification — oral drugs. Schizonepeta has documented interactions with 4 drug classes — the most serious being cytochrome p450 1a2 (cyp1a2) substrates (moderate), cytochrome p450 2d6 (cyp2d6) substrates (moderate) and cytochrome p450 2e1 (cyp2e1) substrates (moderate) — and none of Mineral Oil’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Schizonepeta Does Interact With Other Medications

Schizonepeta has 797 moderate known drug interactions in our database — Mineral Oil isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Schizonepeta

Covers the 2,830 medications we’ve checked against Schizonepeta. Pick one to open its full report.

What to actually watch for

What Schizonepeta Itself Has Been Linked To

This is not an interaction — nothing below involves Mineral Oil. It is the side-effect record for Schizonepeta on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Schizonepeta, this list is the first place to look.

  • Hair loss Additional detail

    “There is currently a limited amount of information available about the adverse effects of schizonepeta. Orally, a specific combination product (Zemaphyte, Phytopharm Plc) containing schizonepeta and numerous other ingredients has been reported to cause nausea, vomiting, colic, dyspepsia, dizziness, headache, and hair loss.”

    Schizonepeta · Natural Medicines adverse-effect record, reported in alopecia.

    2 sources cited
    1. 12620. Fung D, Lau CB. Schizonepeta tenuifolia: chemistry, pharmacology, and clinical applications. J Clin Pharmacol 2002;42:30-6. PubMed
    2. 12626. Zhou S, Koh HL, Gao Y, et al. Herbal bioactivation: the good, the bad and the ugly. Life Sci 2004;74:935-68. PubMed
  • Stomach upset / Vomiting / Nausea Additional detail

    “Orally, a specific combination product (Zemaphyte, Phytopharm Plc) containing schizonepeta and numerous other ingredients has been reported to cause nausea, vomiting, colic, and dyspepsia. However, it is unclear if these effects are due to schizonepeta or the other ingredients.”

    Schizonepeta · Natural Medicines adverse-effect record, reported in dyspepsia.

  • Dizziness / Headache Additional detail

    “Orally, a specific combination product (Zemaphyte, Phytopharm Plc) containing schizonepeta and numerous other ingredients has been reported to cause dizziness and headache. However, it is unclear if these effects are due to schizonepeta or the other ingredients.”

    Schizonepeta · Natural Medicines adverse-effect record, reported in cluster headache.

Everything above comes from the Natural Medicines adverse-effect record for Schizonepeta — expand a row for the licensed statement it rests on. We haven’t matched Mineral Oil to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Mineral Oil.

How to take them

Some Mineral Oil Products Have a Food Rule — Schizonepeta Should Not Break It

At least one FDA label for a product containing Mineral Oil says to take it with food. If you take Schizonepeta on an empty stomach out of habit, keep them separate — and take Mineral Oil with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Mineral Oil products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Directions: * Do not take with meals.

From the Dosage and Administration section of the FDA label we read for Mineral Oil — where that label names a specific product, the instruction is that product's. See the Mineral Oil drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Mineral Oil

This page covers Schizonepeta only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mineral Oil page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Mineral Oil page

“Everything on record for mineral oil (Kondremul Plain) comes down to one theme, absorption in the gut, and it deserves genuine care, chiefly because of activated charcoal. Charcoal binds a wide array of medicines and can sharply cut how much of them the body actually takes in, and it carries this list's only major rating, so understand…”

Reviewed by 2 · Jul 18, 2026

Open the Mineral Oil interaction page

One more smart check

Taking Schizonepeta as Part of a Dietary Supplement Product? Check It for Interactions

We hold 285 real supplement products containing Schizonepeta, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Schizonepeta. Even though Schizonepeta itself has no known interaction with Mineral Oil, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Schizonepeta and Mineral Oil Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Schizonepeta
Top 25%

#347 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mineral Oil
Steady interest

#1,486 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Schizonepeta reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Schizonepeta and Mineral Oil records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Schizonepeta

What is Schizonepeta?

  • Common cold and early-stage fever
  • Itchy skin rashes and hives
  • Sore throat
  • Headache
  • Measles and other skin eruptions (traditional use)

Schizonepeta is a mint-family herb long used in traditional Chinese medicine, usually as part of combination formulas for colds, fevers, and itchy skin conditions. Modern human evidence is very limited, so its benefits are not well proven. Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or taking other medicines.

Schizonepeta tenuifolia · Lamiaceae · Dried aerial parts (stems and flower spikes); sometimes the essential oil · Dried herb for decoctions (tea), powders, capsules, and as part of traditional herbal formulas

An interaction check asks whether these two react with each other — it does not ask whether Schizonepeta is a good idea for someone in your situation. Here is what our Schizonepeta record says about it on its own.

Schizonepeta: dosing

There is no well-established standardized dose for Schizonepeta. In traditional Chinese medicine it is typically used as a dried herb in a decoction, often combined with other herbs, and amounts are tailored by a trained practitioner.For commercial supplements, follow the directions on the product label.

From our Schizonepeta monograph — the full record covers uses, side effects and every documented interaction.

Read the full Schizonepeta monograph & all interactions
Medication

About Mineral Oil

What Is Mineral Oil Used For?

Brand name: Kondremul Plain

Most mineral oil products are used to relieve occasional constipation. Rectal enema products — including Fleet, Leader Ready to Use Mineral Oil, Foster and Thrive Ready to Use Mineral oil, Enema, and Enema Mineral Oil — are also used for relief of fecal impaction (stool that is stuck and won't pass) and to remove residue left in the bowel after a barium procedure.

Humco Mineral Oil Light topical liquid is used to help treat and prevent diaper rash, protect chafed skin, and seal out wetness. HANHOO BlemishPatch is applied directly to skin concerns as a topical patch.

See full Mineral Oil drug information
Keep checking

Other Drugs & Schizonepeta

Browse every other medication we’ve checked against Schizonepeta — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
797Moderate
0Minor
2,032No known interaction
Moderate

797 interactions

Showing 60 of 797 moderate interactions — see all 797 on the Schizonepeta page.

No interaction 2,032 drugs checked — show the list

We also checked Schizonepeta against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,032 medications checked with no known interaction — see the full Schizonepeta list.

Evidence & sources

Schizonepeta References

The 4 references that drive our Schizonepeta monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Fung D, Lau CB. Schizonepeta tenuifolia: chemistry, pharmacology, and clinical applications. J Clin Pharmacol 2002;42:30-6. PubMed
  2. Zhou S, Koh HL, Gao Y, et al. Herbal bioactivation: the good, the bad and the ugly. Life Sci 2004;74:935-68. PubMed
  3. Fung AY, Look PC, Chong LY, et al. A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. Int J Dermatol 1999;38:387-92 . PubMed
  4. Bao B, Geng T, Cao Y, et al. Effects of schizonepetin on activity of mRNA expression of cytochrome P450 enzymes in rats. Int J Mol Sci. 2012;13(12):17006-18.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Schizonepeta and Mineral Oil Together: Common Questions

Is it safe to take Schizonepeta with Mineral Oil?
We do not list a known interaction between Schizonepeta and Mineral Oil. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Schizonepeta and Mineral Oil at the same time of day?
At least one FDA label for a product containing Mineral Oil says to take it with food. If you take Schizonepeta on an empty stomach out of habit, keep them separate and take Mineral Oil with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Mineral Oil products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Schizonepeta and Mineral Oil combination checked?
Interactions in our licensed database are recorded against drug classes. Mineral Oil is filed under 1 classification, and Schizonepeta has documented interactions with 4 drug classes — none of Mineral Oil's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Schizonepeta interact with any other medications?
Yes. Schizonepeta has 797 documented drug interactions in our database — Mineral Oil is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Mineral Oil interact with any supplements?
Yes. Mineral Oil has documented interactions with 17 supplements in our database — Schizonepeta is not one of them. The Mineral Oil interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Mineral Oil and Schizonepeta?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.