Aller-Response By Source Naturals Overview & Drug Interactions

Vitamin B12, also known as cobalamin, is a water-soluble vitamin crucial for several bodily functions. It plays a pivotal role in the formation of red blood cells, aiding in the prevention of anemia. Vitamin B12 is essential for maintaining a healthy nervous system and proper brain function, as it is involved in the synthesis of myelin, the protective sheath around nerve fibers. This vitamin is primarily found in animal-based foods such as meat, fish, dairy products, and eggs, making it important for vegetarians and vegans to consider supplementation. A deficiency in vitamin B12 can lead to neurological issues, fatigue, and cognitive impairment.

Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.

Magnesium is a mineral that is essential for the proper functioning of the body. It plays a role in many important physiological processes, including the contraction and relaxation of muscles, the transmission of nerve impulses, and the regulation of blood pressure. Magnesium is found in a variety of foods, including leafy green vegetables, nuts, and grains, and it is also available as a dietary supplement. There are several different forms of magnesium that are available as supplements, all of which can be used to prevent deficiency. Additionally, magnesium is purported to have several different health benefits, such as improving sleep, reducing muscle cramps, reducing anxiety, and preventing or treating migraines. Although magnesium is essential for health, magnesium-containing foods and supplements can interact with some prescription medications if used at the same time.

Zinc is a mineral that is essential for the proper functioning of the human body. It is involved in many important physiological processes, including immune system function, wound healing, taste, and smell. Zinc is found in a variety of foods, including meat, seafood, and whole grains, and it is also available as a dietary supplement. Zinc supplements may be used to treat or prevent zinc deficiency, which can occur due to certain medical conditions, such as gastrointestinal disorders, alcohol abuse, and certain medications. Zinc supplements may also be used for other purposes, such as to boost the immune system, improve acne, and reduce the severity and duration of colds. There are several different forms of zinc supplements available, including zinc gluconate, zinc acetate, and zinc sulfate. The most common form of zinc supplements is zinc gluconate, which is well absorbed and is less likely to cause stomach-related side effects than other forms of zinc.

Quercetin is a type of flavonoid, which is a class of compounds found in a wide variety of plants and foods. It is purported to have a number of health benefits such as anti-inflammatory, antioxidant, and immune-boosting effects. Studies suggest it may also help to reduce the risk of certain chronic diseases, such as heart disease. In addition, quercetin may have anti-allergic properties and may be helpful in the treatment of allergies and asthma. It is a popular dietary supplement worldwide and is often included in products that contain antioxidants or various vitamins/minerals. Its wide range of potential health benefits mean that it could potentiate the effects of other drugs (e.g., anti-hypertensives), which is why there are an abundant number of potential interactions listed for quercetin.

Bromelain is a group of proteolytic enzymes derived from pineapples. It has been traditionally used for its anti-inflammatory and protein-digesting properties. Some research suggests it may have potential benefits for conditions such as allergic rhinitis, burns, cancer, diabetic foot ulcers, and postoperative pain, among others. However, the evidence for its effectiveness in these areas is lacking, and more research is needed. It is important to note that bromelain should not be confused with other protein-digesting enzymes. Pregnant and lactating individuals should avoid using bromelain due to insufficient information about its safety in these populations.

Turmeric is a commonly used spice and a member of the ginger family (Zingiberaceae). It is native to India and other parts of South Asia and is known for its bright orange-yellow color and its warm, slightly bitter flavor. In traditional medicine, turmeric is believed to have a number of health benefits due to its high content of antioxidants and other compounds, such as curcumin. It is thought to have anti-inflammatory and antimicrobial properties, and it is often used to treat a variety of conditions, including joint pain, digestive problems, skin disorders, and respiratory infections. Most dietary supplements that utilize turmeric standardize their products based on a specific amount of curcumin (curcuminoids) per dose. Additionally, turmeric supplements are often paired with black pepper extract (piperine) to improve oral absorption.

Vitamin E is a fat-soluble vitamin found naturally in a variety of foods, including vegetable oils, nuts, seeds, and leafy green vegetables. Vitamin E is also available as a dietary supplement and is often added to skincare products. Vitamin E has many roles in the body, including protecting cells from oxidative stress and supporting immune function.

Indian long pepper, also known as pippali or pipali, is a plant species native to India and other parts of South and Southeast Asia. It is a member of the Piperaceae family. The fruit of the plant, which has a pungent, slightly sweet flavor, is harvested and dried for use as a spice. Indian long pepper has also been used in Ayurvedic medicine to treat a variety of ailments, including digestive problems, pain, poor blood circulation, respiratory disorders, and fever. One of the constituents of Indian long pepper is piperine, which can have wide ranging effects, including increasing the bioavailability (i.e., rate and extent of absorption) of several different drugs. It is often combined with over-the-counter supplements, like turmeric, to increase their absorption.

Stinging nettle (Urtica dioica) is a perennial flowering plant that belongs to the Urticaceae family. It is native to Europe, Asia, and North America, and is characterized by its green leaves and small, greenish-white flowers. Stinging nettle has small, stinging hairs on its leaves and stems, which can cause a painful rash when touched. The leaves and the roots of stinging nettle have been used in traditional medicine to treat a variety of conditions such as joint pain, diabetes, enlarged prostate, anemia, and urinary tract infections. It is also used as a diuretic and to help with allergies as it contains the compound quercetin. The leaves and stems of the plant are edible and can be consumed as a vegetable, usually after boiling or steaming to remove the stinging hairs, as the plant is rich in vitamins, minerals, and antioxidants.

Indian gooseberry, also known as amla, is a fruit that is native to India. It is purported to have a range of potential health benefits, including supporting immune function, improving blood cholesterol levels, improving digestion, and reducing inflammation. It is also thought to have antioxidant and anti-aging properties. When used in dietary supplements, typically it will be an extract of the whole fruit and seeds.

Andrographis is a type of plant native to Asia and is commonly used in traditional medicine. It is a member of the Acanthaceae family and is sometimes referred to as "Indian echinacea." Andrographis is believed to have a number of potential health benefits and is often used to treat infections, such as the common cold and flu, as well as other health conditions. Studies have shown that Andrographis contains a number of compounds, and dietary supplements are often standardized with a specific amount of one in particular, andrographolide.

Ginkgo (Ginkgo biloba) is a tree native to Asia and is known for its distinctive fan-shaped leaves. The extract of the ginkgo leaf is commonly used in traditional medicine and is one of the most popular dietary supplements consumed worldwide. Its most common use is to help improve memory and cognitive function.

Ginger is a spice native to Asia and part of the Zingiberaceae family. It has a pungent, spicy flavor and is often used to add flavor to dishes and drinks. Ginger has a long history of use in traditional medicine and is believed to have anti-inflammatory, antioxidant, and other medicinal properties. It is commonly used to treat nausea, motion sickness, and other digestive issues. Ginger is also sometimes used to relieve pain and reduce inflammation. Ginger supplements generally standardize several compounds found in the root, and are often labeled as containing a certain amount of 'ginger root extract'.

Licorice, also known as glycyrrhiza, is a plant native to parts of Europe, Asia, and the Mediterranean region. The root of the plant has been used for centuries in traditional medicine and is often consumed in the form of candy, tea, and supplements. Licorice has a number of purported health benefits, including the ability to soothe sore throats, reduce inflammation, and improve digestive problems. It may also have antiviral and antibacterial properties. Licorice naturally contains glycyrrhizin, or glycyrrhizic acid, which can have toxic effects if consumed in large amounts. However, licorice can be processed to remove glycyrrhizin, resulting in DGL (deglycyrrhizinated licorice). Many dietary supplements that contain deglycyrrhizinated licorice are often simply named 'DGL'.

Black pepper is a spice made from the dried, unripe fruit of the Piper nigrum plant, which is native to the southwestern coast of India. It is one of the most widely used spices in the world, and it is often utilized to add flavor and heat to a wide variety of dishes. In traditional medicine, black pepper is purported to have a number of health benefits. It is a good source of antioxidants and is thought to have anti-inflammatory properties, which may make it useful in reducing inflammation and swelling in the body. Black pepper is also used as a natural remedy for digestive problems, such as indigestion and bloating, and to boost the immune system. Black pepper is widely used in dietary supplements, specifically, an extract from black pepper known as piperine. Piperine can affect the absorption of many drugs, which is why it has a large number of reported interactions. Oftentimes, these 'interactions' are purposeful, such as when piperine is used with turmeric, to increase its absorption.