Interactions on record — worth a quick check against your medications. Based on 5 of 8 ingredients. Check your meds →
Dietary supplement

Creature Citrus Flavor Ingredients & Drug Interactions

by Beast Sports Nutrition

Creature Citrus Flavor label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Creature Citrus Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Creature Citrus Flavor is a dietary supplement by Beast Sports Nutrition with 8 active ingredients. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.Based on those ingredients, 693 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chromium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Creature Citrus Flavor by Beast Sports Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Creature Citrus Flavor by Beast Sports Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Creature Citrus Flavor by Beast Sports Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 11 active ingredients.
  • “Creature 5X Complex” is a proprietary blend — the label gives one combined amount (4,000 mg) without saying how much of each component you get.
  • “Creatine Optimizers” is listed as a grouped ingredient — the label gives one combined amount (92.50 mg) without saying how much of each component you get.

Creature Citrus Flavor contains 11 active ingredients, most of them forms of creatine (Creatine Anhydrous, Creatine Gluconate, Creatine Monohydrate, and Crea-Trona) plus supporting compounds in what the label calls the Creature 5X Complex and Creatine Optimizers. Beyond the creatine sources, you're also getting Chromium Picolinate and Chromium for blood sugar support, Biotin for skin and hair, and Cinnamon bark extract and Banaba leaf extract for additional glucose management.

One ingredient, Di-Creatine Malate, is not available in our database. The inactive ingredients include malic acid, natural and artificial flavors, silicon dioxide, citric acid, soluble dietary fiber, sucralose, and turmeric — these are the fillers, thickeners, and flavor components that make up the powder.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: fuel muscle growth, strength, and recovery.
  • We looked for evidence on: Athletic performance, Muscle strength, Physical performance, Muscle breakdown, Postoperative recovery, Sarcopenia — and 4 related terms.
  • The strongest evidence on file: Creatine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Creatine is rated "Possibly Effective" for Muscle strength, Sarcopenia.
  • Also on file: Creatine is rated "Insufficient Reliable Evidence To Rate" for HIV/AIDS-related wasting, Chronic fatigue syndrome (CFS), Muscle breakdown, Muscular dystrophy.

The creatine forms in this product — all the Creatine Anhydrous, Creatine Gluconate, Creatine Monohydrate, and Crea-Trona — are possibly effective for muscle strength, athletic performance, and sarcopenia (age-related muscle loss), and possibly effective for certain rare cerebral creatine deficiency syndromes. Evidence does not support creatine for Huntington disease or osteopenia.

Chromium is possibly effective for diabetes and likely effective for chromium deficiency, though it's possibly ineffective for prediabetes, schizophrenia, and high blood pressure. Biotin is likely effective for biotin deficiency but possibly ineffective for multiple sclerosis and seborrheic dermatitis.

The evidence for cinnamon bark extract and banaba leaf extract is insufficient — we don't have reliable data showing they work for the conditions they're marketed for, including diabetes and prediabetes.

The evidence, ingredient by ingredient Biotin Chromium Creatine Cassia Cinnamon Banaba

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chromium is generally well tolerated at typical supplement doses, but high or long-term use may pose risks. Most common side effects are gastrointestinal irritation, headaches, insomnia, irritability, and mood changes.

Rare serious effects include kidney and liver damage and blood disorders. Skin reactions like rashes and dermatitis have been reported.

Creatine is generally well tolerated in healthy adults but is caution in people with kidney problems — common side effects are dehydration, diarrhea, muscle cramps, and water retention. Rare serious concerns include kidney damage and blood clots.

Biotin is generally considered safe even at high doses. Cinnamon bark extract is generally safe in food amounts but carries a moderate concern about liver damage with large supplement doses over time due to its coumarin content.

Banaba appears well tolerated in short studies, though long-term safety is not well established; reported side effects include dizziness, headache, tremor, and weakness, though it's unclear if banaba alone caused them. For pregnancy: chromium and biotin are likely safe; cinnamon bark extract is likely safe; banaba lacks safety data.

For nursing: biotin is likely safe; chromium is likely safe; banaba and creatine lack sufficient data. Creatine should be avoided in pregnancy and nursing because safety has not been established.

Side effects, ingredient by ingredient Biotin Chromium Creatine Cassia Cinnamon Banaba

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 5 matched ingredients can interact with medications — Chromium, Cassia Cinnamon, Banaba.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 694 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you take insulin or diabetes medications (including metformin, sulfonylureas, and others) — chromium and banaba may lower your blood sugar further and raise hypoglycemia risk. If you're on thyroid replacement (levothyroxine, Synthroid, etc.), chromium may reduce how much gets absorbed; space them apart.

Blood pressure medications (ACE inhibitors, beta-blockers, calcium channel blockers, and others) could have stronger effects when combined with chromium or banaba. If you take any medication metabolized by organic anion transporters in your liver, banaba may reduce its effectiveness — ask your pharmacist for a specific list.

NSAIDs like ibuprofen and naproxen or aspirin may increase chromium levels. Medications that stress the liver should be discussed with your provider if you're taking high-dose cinnamon.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Creature Citrus Flavor is designed for athletes and gym-goers wanting creatine to support muscle and performance. If you take insulin, diabetes medications, thyroid medication, blood pressure medication, or anything processed by your liver, you need to check your exact drugs before starting this product — the chromium, cinnamon, and banaba can interfere with how they work or increase side effects like low blood sugar.

Those with kidney problems should be cautious with creatine. Talk to your doctor or pharmacist before adding this to your routine, especially if you're pregnant, nursing, or managing any chronic condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 10 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Creature Citrus Flavor, straight from the product label.

Brand Beast Sports Nutrition
Barcode (UPC) 631312801018
Net contents 11.64 Ounce(s); 330 Gram(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 249624
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Creature Citrus Flavor by Beast Sports Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5.5 Gram(s)
Maximum serving Sizes:
5.5 Gram(s)
Servings per container
60
UPC/BARCODE
631312801018
IngredientAmount% DV
Chromium Picolinate0 NP--
Biotin200 mcg72%
Creatine Anhydrous0 NP--
Chromium50 mcg47%
Creatine Gluconate0 NP--
Di-Creatine Malate0 NP--
Cinnamon bark extract0 NP--
Banaba (Lagerstroemia speciosa) leaf extract0 NP--
Crea-Trona0 NP--
Creature 5X Complex4000 mg--
Creatine Monohydrate0 NP--
Creatine Optimizers92.5 mg--
Biotin0 NP--

Other ingredients: Malic Acid, Natural and Artificial flavors, Silicon Dioxide, Citric Acid, Soluble Dietary Fiber, Sucralose, Turmeric

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

The creatines behind creature.

The strongest name in sports nutrition

Formula

Creature is a blend of five advanced forms of creatine that are quality-tested to assure maximum potency. It also contains key nutraceuticals to help your muscles maximize every dose. Creatine fuels intense weight training and endurance activities to help you push harder, go faster, and recover quicker.

5 forms of creatine + creatine optimizers to help fuel muscle growth, increase strength and accelerate recovery.

Citrus flavor natural & artificial

Formulation

In the process it stimulates lean muscle mass, acts as a support system to prevent muscle breakdown, and aids in muscle recovery.

Beast ingredients are routinely tested for: Raw material identification. Microbials to detect bacteria and mold. Heavy metals including mercury and lead.

Fuel the beast Strength Muscle Endurance

Manufactured in the USA from domestic and/or imported ingredients in a FDA-compliant facility.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 3 capsules 30 minutes prior to workout and 3 capsules immediately after workout. Always take with plenty of water. On non-workout days, take 3 capsules in the morning and 3 capsules in the evening.

FDA Statement of Identity

Dietary Supplement

Precautions

Allergen warning: This product was produced in a facility that may also process ingredients containing milk, eggs, soybeans, shellfish, fish, tree nuts, wheat and peanuts.

Warning: For healthy adults 18 years of age and older.

Do not use if you are pregnant, nursing, anticipating surgery, taking medicine, or under medical supervision.

Keep out of reach of children.

Do not use if seal is broken or missing.

Storage

Storage conditions: Store in a cool dry place.

Brand IP Statement(s)

Chromax including the Chromax logo is a registered trademark of Nutrition, LLC. Chromax is patented protected.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Creature Citrus Flavor by Beast Sports Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Creature Citrus Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Creature Citrus Flavor by Beast Sports Nutrition

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size5.5 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Biotin

No known
interactions
200 mcg per serving Form: D-Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Chromium

Interacts with
178 drugs
50 mcg per serving Form: Chromax Chromium Picolinate

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

Creature 5X Complex

4000 mg per serving

Creatine Optimizers

No known
interactions
92.5 mg per serving

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...

Creatine Optimizers monograph & interactions

Other (inactive) ingredients: Malic Acid, Natural and Artificial flavors, Silicon Dioxide, Citric Acid, Soluble Dietary Fiber, Sucralose, Turmeric. These complete the product’s ingredient list but are not active constituents.

Interaction report

Creature Citrus Flavor by Beast Sports Nutrition Drug Interactions

Want to check YOUR meds against Creature Citrus Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
693Drugs
616 Moderate 77 Minor

Ingredients driving the most interactions

Chromium 178

Individual Drug Interactions

The ingredients in Creature Citrus Flavor interact with 693 drugs. Click any drug to see the details.

1 of the 8 ingredients in Creature Citrus Flavor interact with drugs. Each result below shows which ingredient is responsible. Chromium

Each ingredient & the kinds of drugs it affects

For each ingredient in Creature Citrus Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Creature Citrus Flavor, from the product label.

Beast Sports Nutrition

See all Beast Sports Nutrition products
Name
Beast Sports Nutrition
Street Address
7491 North Federal Hwy. C5-148
City
Boca Raton
State
FL
ZipCode
33487
Web Address
beastsports.com
Pharmacist Counseling Corner

Creature Citrus Flavor by Beast Sports Nutrition: Common Questions

Does Creature Citrus Flavor by Beast Sports Nutrition interact with any medications?
Yes. Based on its ingredients, Creature Citrus Flavor has a known interaction with 693 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Creature Citrus Flavor contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product have creatine in it?
Yes — it actually has multiple forms. You're getting Creatine Anhydrous, Creatine Monohydrate, Creatine Gluconate, and Crea-Trona, plus a proprietary blend that includes even more creatine-supporting compounds. That's the whole point of the product.
Is this safe if I have kidney disease?
The data says creatine is generally well tolerated in healthy adults, but people with kidney problems need to be careful — your kidneys handle creatine clearance, so if they're not working well, talk to your doctor or nephrologist before taking it.
Can I take this while pregnant or nursing?
Safety during pregnancy and nursing hasn't been established for creatine — avoid it. Chromium and biotin are likely safe, and cinnamon is likely safe, but the creatine content makes this product not recommended. Talk to your obstetrician or midwife for personalized advice.
Does cinnamon in this product affect my liver?
Food amounts of cinnamon are generally fine, but this is a supplement dose. Long-term, high-dose cinnamon may pose liver concerns because it contains coumarin, which can cause liver damage in large amounts over time. If you have liver issues or take medication that stresses your liver, check with your doctor first.
Will this help my muscle strength?
The creatine in it is possibly effective for muscle strength and athletic performance, especially if you're training. Chromium is possibly effective for diabetes but not specifically for muscle. The evidence for cinnamon and banaba for strength is not established.
What are the most common side effects?
From creatine: dehydration, diarrhea, muscle cramps, and water retention. From chromium: gastrointestinal upset, headaches, and mood changes. Most people tolerate it well, but if you notice stomach upset or cramping, scale back and talk to your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Creature Citrus Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Creature Citrus Flavor label
Go deeper

The Full Monographs Behind Creature Citrus Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...

Read the full Biotin monograph → Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph → Herb & supplement monograph

Creatine

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...

Read the full Creatine monograph → Herb & supplement monograph

Cassia Cinnamon

Interacts with 442 drugs

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...

Read the full Cassia Cinnamon monograph → Herb & supplement monograph

Banaba

Interacts with 299 drugs

Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may modestly lower glucose. The overall evide...

Read the full Banaba monograph →
Sources

Sources & How We Checked

Creature Citrus Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 170 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chromium 53 references
  1. Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
  2. Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
  3. Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
  4. Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
  5. Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
  6. Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
  7. McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
  8. Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
  9. Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
  10. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  11. Rabinovitz H, Friedensohn A, Leibovitz A, et al. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res 2004;74:178-82. PubMed
  12. Lanca S, Alves A, Vieira AI, et al. Chromium-induced toxic hepatitis. Eur J Intern Med 2002;13:518-20. PubMed
  13. Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
  14. Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry 2003;53:261-4.. PubMed
  15. Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
  16. Mouser JF, Hak EB, Helms RA, et al. Chromium and zinc concentrations in pediatric patients receiving long-term parenteral nutrition. Am J Health Syst Pharm 1999;56:1950-6. PubMed
  17. Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
  18. Wani S, Weskamp C, Marple J, Spry L. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. Ann Pharmacother 2006;40:563-6. PubMed
  19. Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care 2006;29: PubMed
  20. Martin J, Wang ZQ, Zhang XH, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006;29:1826-32. PubMed
  21. Singer GM, Geohas J. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43. PubMed
  22. John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007;17:763-5. PubMed
  23. Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med 2010;16:291-9. PubMed
  24. Davis ML, Seaborn CD, and Stoecker BJ. Effects of over-the-counter drugs on chromium retention and urinary excretion in rats. Nutrition Research 1995;15(2):201-210.
  25. Young P, Turiansky G, Bonner M, and et al. Acute generalized exanthematous pustulosis induced by chromium picolinate. J.Am Acad.Dermatol. 1999;41(5 Pt 2):820-823. PubMed
  26. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Lung cancer among workers in chromium chemical production. Am J Ind.Med 2000;38(2):115-126. DOI
  27. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Clinical findings of irritation among chromium chemical production workers. Am J Ind.Med 2000;38(2):127-131. PubMed
  28. Pittler, M. H. and Ernst, E. Dietary supplements for body-weight reduction: a systematic review. Am.J.Clin Nutr. 2004;79(4):529-536. PubMed
  29. Pei, D., Hsieh, C. H., Hung, Y. J., Li, J. C., Lee, C. H., and Kuo, S. W. The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Metabolism 2 PubMed
  30. Hisatomi, K., Ishii, H., Hashiguchi, K., Seki, M., Ide, M., Sugiyama, K., Ishimoto, H., Nakayama, S., Mukae, H., and Kohno, S. Interstitial pneumonia caused by inhalation of fumes of nickel and chrome. Respirology. 2006;11(6):814-817. PubMed
  31. Kleefstra, N., Houweling, S. T., Bakker, S. J., Verhoeven, S., Gans, R. O., Meyboom-de Jong, B., and Bilo, H. J. Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled tri DOI
  32. Parsons, A., Ingram, J., Inglis, J., Aveyard, P., Johnstone, E., Brown, K., Franklin, M., and Bermudez, I. A proof of concept randomised placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to pr
  33. Bagdon RE and Hazen RE. Skin permeation and cutaneous hypersensitivity as a basis for making risk assessments of chromium as a soil contaminant. Environ.Health Perspect. 1991;92:111-119. PubMed
  34. Bharmal, S. V., Moyes, V., Ahmed, S., and Grossman, A. Hypoglycaemia: possible mediation by chromium salt medication. Hormones.(Athens.) 2010;9(2):181-183. PubMed
  35. Krol, E., Krejpcio, Z., Byks, H., Bogdanski, P., and Pupek-Musialik, D. Effects of chromium brewer's yeast supplementation on body mass, blood carbohydrates, and lipids and minerals in type 2 diabetic patients. Biol.Trace Elem.Res. 2011;143(2):726-737.
  36. Unisa, S., Jagannath, P., Dhir, V., Khandelwal, C., Sarangi, L., and Roy, T. K. Population-based study to estimate prevalence and determine risk factors of gallbladder diseases in the rural Gangetic basin of North India. HPB (Oxford) 2011;13(2):117-125. PubMed
  37. Noda, S., Asano, Y., and Sato, S. Lichen planus in a patient with long-term exposure to chrome. Eur.J.Dermatol. 2011;21(3):417-418. PubMed
  38. Xiang, J., Sun, Z., and Huan, J. N. Intensive chromic acid burns and acute chromium poisoning with acute renal failure. Chin Med.J.(Engl.) 7-5-2011;124(13):2071-2073.
  39. Chhabra, D., Oda, K., Jagannath, P., Utsunomiya, H., Takekoshi, S., and Nimura, Y. Chronic heavy metal exposure and gallbladder cancer risk in India, a comparative study with Japan. Asian Pac.J.Cancer Prev. 2012;13(1):187-190. PubMed
  40. Huszonek, J. Over-the-counter chromium picolinate. Am J Psychiatry 1993;150(10):1560-1561. PubMed
  41. Bunner S and McGinnis R. Chromium-induced hypoglycemia. Psychosomatics 1998;39(3):298-299. PubMed
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Biotin 4 references
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Creatine 86 references
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Cassia Cinnamon 20 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
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Banaba 7 references
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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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