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Dietary supplement

GlucoFit Ingredients & Drug Interactions

by NOW

GlucoFit label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking GlucoFit against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

GlucoFit is a dietary supplement by NOW with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, type 2 diabetes, weight management.Based on those ingredients, 299 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Banaba leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against GlucoFit by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with GlucoFit by NOW — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of GlucoFit by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

GlucoFit is a single-ingredient softgel containing banaba leaf extract. Banaba is a plant used traditionally to support healthy blood sugar levels.

The capsule also contains inactive ingredients including rice bran oil, silica, and beeswax.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Banaba's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support healthy glucose metabolism.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (prediabetes), Metabolic syndrome, Blood sugar regulation, Insulin sensitivity.
  • The closest evidence on file: Banaba is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Banaba is rated "Insufficient Reliable Evidence To Rate" for Impaired glucose tolerance (prediabetes), Metabolic syndrome.

The evidence for banaba in GlucoFit isn't established in our data. Studies on banaba for diabetes, prediabetes (impaired glucose tolerance), and metabolic syndrome all show insufficient reliable evidence to rate whether it actually works.

If you're considering this product for blood sugar support, talk with your doctor or pharmacist about whether the evidence is strong enough for your situation.

The evidence, ingredient by ingredient Banaba

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Banaba extract is generally well tolerated in the short studies available, but we don't have good data on long-term safety — so it's worth knowing that's a gap. The most commonly reported side effects with a banaba-containing product have been dizziness, headache, tremor, weakness, stomach upset, and heart palpitations, though it's unclear whether banaba itself or another ingredient in that product caused them.

Banaba is not recommended during pregnancy or while breastfeeding, as there isn't enough safety data.

Side effects, ingredient by ingredient Banaba

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Banaba.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 299 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking GlucoFit, check your blood pressure medications and any diabetes drugs you're on — banaba can add to their effects. Also verify any medications that use the OATP transport system, since banaba may reduce how much of them your body absorbs.

Use the search tool on this page to look up your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

GlucoFit might appeal to you if you're looking for a plant-based approach to blood sugar support, but the evidence for it isn't well established. If you take blood pressure or diabetes medications, or any drug that uses the OATP transport system, you'll need to check with your pharmacist before starting — the interactions are real.

Talk to your doctor or pharmacist about whether this product fits your health plan.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GlucoFit, straight from the product label.

Brand NOW
Barcode (UPC) 733739030955
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Aug 22, 2017
DSLD ID 77755
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GlucoFit by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
733739030955
IngredientAmount% DV
Calories5 Calorie(s)--
Total Fat0.5 Gram(s)1%
Banaba leaf extract1.334 mg--

Other ingredients: Rice Bran Oil, Softgel Capsule, Silica, Beeswax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1 softgel 2 times daily with food.

Formula

GlucoFit is a dietary ingredient extracted from the herb Banaba (Lagerstroemia speciosa), standardized to 18% Corosolic Acid.

18% Corosolic Acid

Brand IP Statement(s)

GlucoFit's active component, Corosolic Acid, has been shown in scientific studies to support healthy glucose metabolism.

GlucoFit is a registered trademark of Soft Gel Technologies, Inc.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition (including diabetes or low blood sugar).

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, corn, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

General Statements

Natural color variation may occur in this product.

Softgel size

Supports glucose metabolism Helps maintain blood sugar levels already within normal range

General Health Family owned since 1968.

General

CODE 3095 V7

Seals/Symbols

Non-GMO

GMP Quality Assured

Formulation

Non-GMO

Not manufactured with wheat, gluten, soy, corn, milk, egg, fish or shellfish ingredients.

FDA Statement of Identity

A Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

GlucoFit by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

GlucoFit label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in GlucoFit by NOW

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Banaba leaf extract

Interacts with
299 drugs
1.334 mg per serving Form: Corosolic Acid

Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may m...

Banaba leaf extract monograph & interactions

Other (inactive) ingredients: Rice Bran Oil, Softgel Capsule, Silica, Beeswax. These complete the product’s ingredient list but are not active constituents.

Interaction report

GlucoFit by NOW Drug Interactions

Want to check YOUR meds against GlucoFit?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
299Drugs
299 Moderate

Ingredients driving the most interactions

Banaba leaf extract 299

Individual Drug Interactions

The ingredients in GlucoFit interact with 299 drugs. Click any drug to see the details.

1 of the 1 ingredient in GlucoFit interact with drugs. Each result below shows which ingredient is responsible. Banaba leaf extract

Each ingredient & the kinds of drugs it affects

For each ingredient in GlucoFit with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Banaba leaf extract3 drug types · 299 drugs

Antidiabetes Drugs

Theoretically, concomitant use of banaba and hypoglycemic drugs might have additive effects.
Human and animal research suggests that banaba can lower blood glucose levels.

Likelihood Probable Evidence B
Antihypertensive Drugs

Theoretically, concomitant use of banaba and antihypertensive drugs might cause additive effects.
Human and animal research suggests that banaba can lower blood pressure.

Likelihood Probable Evidence B
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Theoretically, concomitant use of banaba with substrates of OATP might reduce the bioavailability of the OATP substrate.
In vitro research shows that banaba inhibits OATP, particularly OATP2B1. OATPs are expressed in the small intestine and liver and are responsible for the absorption of drugs and other compounds.

Likelihood Possible Evidence D
Banaba leaf extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for GlucoFit, from the product label.

NOW

See all NOW products
Name
NOW Foods
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

GlucoFit by NOW: Common Questions

Does GlucoFit by NOW interact with any medications?
Yes. Based on its ingredients, GlucoFit has a known interaction with 299 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
GlucoFit contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take GlucoFit if I'm pregnant or breastfeeding?
No — banaba isn't recommended during pregnancy or breastfeeding because there isn't enough safety data. If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before considering this product.
What's banaba leaf extract and what is it supposed to do?
Banaba is a plant traditionally used to help with blood sugar levels. GlucoFit contains an extract of the leaf, though our data shows the evidence for how well it actually works isn't well established yet.
What side effects might I notice?
Banaba extract is generally well tolerated. Side effects reported in studies have included dizziness, headache, tremor, weakness, and stomach upset — though it's not always clear whether banaba itself or other ingredients caused them.
Is this safe to use long-term?
Short-term studies show banaba is generally well tolerated, but we don't have good data on long-term safety. If you're thinking about taking it for weeks or months, mention that to your pharmacist.
Does GlucoFit have fillers or other inactive ingredients?
Yes — along with the banaba extract, it contains rice bran oil, silica, and beeswax as inactive ingredients that help make the softgel capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if GlucoFit is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GlucoFit label
Go deeper

The Full Monographs Behind GlucoFit’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Banaba

Interacts with 299 drugs

Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may modestly lower glucose. The overall evide...

Read the full Banaba monograph →
Sources

Sources & How We Checked

GlucoFit's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Banaba 7 references
  1. Judy WV, Hari SP, Stogsdill WW, et al. Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics. A dose-dependence study. J Ethnopharmacol 2003;87:115-7. PubMed
  2. Kakuda T, Sakane I, Takihara T, et al. Hypoglycemic effect of extracts from Lagerstroemia speciosa L. leaves in genetically diabetic KK-AY mice. Biosci Biotechnol Biochem 1996;60:204-8.
  3. Fukushima, M., Matsuyama, F., Ueda, N., Egawa, K., Takemoto, J., Kajimoto, Y., Yonaha, N., Miura, T., Kaneko, T., Nishi, Y., Mitsui, R., Fujita, Y., Yamada, Y., and Seino, Y. Effect of corosolic acid on postchallenge plasma glucose levels. Diabetes Res C PubMed
  4. Yamaguchi, Y., Yamada, K., Yoshikawa, N., Nakamura, K., Haginaka, J., and Kunitomo, M. Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome. Life Sci 11-25-2006;79(26):2474-2479. PubMed
  5. Fuchikami H, Satoh H, Tsujimoto M, Ohdo S, Ohtani H, Sawada Y. Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 2006;34:577-82. PubMed
  6. Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
  7. Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple

See these in context on the Banaba monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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