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Dietary supplement

Hemp Extract Ingredients & Drug Interactions

by Charlotte's Web Stanley Brothers

Hemp Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hemp Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hemp Extract is a dietary supplement by Charlotte's Web Stanley Brothers with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Hemp Extract by Charlotte's Web Stanley Brothers

Ask about any prescription or over-the-counter medication and we check it for interactions with Hemp Extract by Charlotte's Web Stanley Brothers — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Hemp Extract by Charlotte's Web Stanley Brothers

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: hemp extract. It's combined with organic extra virgin olive oil and a vegetable capsule as inactive ingredients.

Hemp extract comes from the hemp plant and contains compounds that research suggests may affect hormone levels, blood pressure regulation, blood clotting, and how your liver processes certain medications. The exact active compounds and their concentrations in this particular product aren't specified in the available data.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hemp product and its label doesn't state a use — see Hemp's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that hemp extract is effective for constipation, atopic dermatitis (eczema), or familial hypercholesterolemia (a genetic cholesterol condition). For each of these uses, the data shows insufficient reliable evidence to make a rating.

If you're considering this product for any specific health goal, talk with your doctor about whether the evidence supports its use for your situation.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods in normal amounts are generally well tolerated, but concentrated extracts like this one are less studied. The data advises caution with supplements and extracts due to limited safety information.

In food amounts, hemp seed is likely okay; serious side effects are rare but include occasional cases of allergic reactions ranging from hives and facial swelling to anaphylaxis and breathing problems. There's also a rare case report of liver inflammation in a young child given very high doses of hemp extract for seizures.

In normal supplement doses, hemp products appear well tolerated. We don't have pregnancy and lactation safety data on file for this ingredient, so there isn't enough information to know either way.

If you're pregnant, breastfeeding, or planning to be, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on hormone therapy (estrogens), blood pressure medications, blood thinners, or drugs your liver breaks down—especially those for heart rhythm or certain infections. While animal research suggests hemp extract may interfere with these, human evidence is limited, so it's worth confirming your exact medications are compatible.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a single-ingredient hemp extract product that's generally well tolerated in typical amounts, but it has documented interactions with hormone therapy, blood pressure medications, blood thinners, and certain liver-processed drugs. The evidence for its effectiveness in the conditions studied isn't established yet.

If you take any of those medication types—especially hormone therapy or blood thinners—check your specific drugs with the tool on this page or talk with your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hemp Extract, straight from the product label.

Brand Charlotte's Web Stanley Brothers
Barcode (UPC) 843119102506
Net contents 7 Liquid Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2020
DSLD ID 239231
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hemp Extract by Charlotte's Web Stanley Brothers, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
7
UPC/BARCODE
843119102506
IngredientAmount% DV
Calories10 Calorie(s)--
Total Fat1 Gram(s)1%
Hemp extract24 mg--

Other ingredients: organic extra virgin Olive Oil, Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested Use Adults: Take one capsule up to two times daily.

Storage

Store at room temperature away from light.

Precautions

Do not use if safety seal is broken or missing.

Keep out of reach of children.

As with any dietary supplement, consult your physician before use if you are pregnant, nursing, have or suspect a medical condition or are taking any medications.

Formulation

Gluten free Non-GMO

100% Vegan

Seals/Symbols

H US Hemp Authority Certified

General Statements

Please recycle

15 7 capsules 7

Formula

15 mg Plant-based cannabinoids per capsule

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hemp Extract by Charlotte's Web Stanley Brothers label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hemp Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hemp Extract by Charlotte's Web Stanley Brothers

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container7 Amounts shown are per serving.

Hemp extract

Interacts with
938 drugs
24 mg per serving Form: Total Phytocannabinoids

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Hemp extract monograph & interactions

Other (inactive) ingredients: Organic extra virgin Olive Oil, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hemp Extract by Charlotte's Web Stanley Brothers Drug Interactions

Want to check YOUR meds against Hemp Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

Hemp extract 938

Individual Drug Interactions

The ingredients in Hemp Extract interact with 938 drugs. Click any drug to see the details.

1 of the 1 ingredient in Hemp Extract interact with drugs. Each result below shows which ingredient is responsible. Hemp extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Hemp Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Hemp extract6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Hemp extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hemp Extract, from the product label.

Charlotte's Web Stanley Brothers

See all Charlotte's Web Stanley Brothers products
Name
Charlotte's Web, Inc.
City
Boulder
State
CO
ZipCode
80302
Phone Number
1.855.790.8169
Web Address
charlottesweb.com
Pharmacist Counseling Corner

Hemp Extract by Charlotte's Web Stanley Brothers: Common Questions

Does Hemp Extract by Charlotte's Web Stanley Brothers interact with any medications?
Yes. Based on its ingredients, Hemp Extract has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hemp Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on birth control or hormone therapy?
Hemp extract may theoretically interfere with estrogen-based therapies due to its estrogenic effects, though this finding comes from animal research and isn't fully understood. Check with your doctor or pharmacist before combining them — they'll know your specific situation best.
What are the side effects?
In normal amounts, hemp seed products are generally well tolerated with few side effects. Rare serious effects include allergic reactions (hives, facial swelling, shortness of breath, even anaphylaxis) and very rarely liver inflammation at very high doses. If you have a history of seed allergies, be extra cautious.
Is it safe to take while pregnant or breastfeeding?
We don't have pregnancy or breastfeeding safety data on file for hemp extract, so there isn't enough information to know either way. Talk with your doctor or pharmacist about whether it's right for you in these situations.
Does this product actually work for anything?
The evidence we hold shows insufficient reliable data to say whether hemp extract is effective for constipation, eczema, or high cholesterol. If you're considering it for a specific health reason, discuss that with your doctor to see if the evidence supports its use.
What's in the capsule besides the hemp extract?
The capsule contains organic extra virgin olive oil as a carrier and a vegetable capsule shell. There are no other active ingredients.
Can this affect how my blood thinners work?
Animal research shows hemp seed can inhibit platelet aggregation in test tubes, but human studies of 2 grams daily for 12 weeks didn't show this effect. Still, it's a documented theoretical interaction — check with your pharmacist or doctor before adding this to your blood thinner regimen.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hemp Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hemp Extract label
Go deeper

The Full Monographs Behind Hemp Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hemp

Interacts with 938 drugs

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...

Read the full Hemp monograph →
Sources

Sources & How We Checked

Hemp Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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