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Dietary supplement

Holy Basil Ingredients & Drug Interactions

by Oregon's Wild Harvest

Holy Basil label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Holy Basil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Holy Basil is a dietary supplement by Oregon's Wild Harvest with 1 active ingredient. Its ingredients are commonly taken for stress and anxiety, blood sugar support, respiratory complaints.Based on those ingredients, 212 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Biodynamic & organic Holy Basil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Holy Basil by Oregon's Wild Harvest

Ask about any prescription or over-the-counter medication and we check it for interactions with Holy Basil by Oregon's Wild Harvest — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Holy Basil by Oregon's Wild Harvest

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This is a straightforward single-ingredient product: biodynamic and organic holy basil extract in liquid form. The extract is suspended in biodynamic and organic alcohol and distilled water, which serve as the carrier base so you can take it as a liquid.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Holy Basil's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: improve stamina and support longevity.
  • We looked for evidence on: Aging, vitality, endurance, healthspan.
  • The closest evidence on file: Holy Basil is rated "Insufficient Reliable Evidence To Rate" for Aging (Natural Medicines).

The evidence for holy basil isn't established in the data we hold. The product facts note insufficient reliable evidence for generalized anxiety, asthma, headache, respiratory infections, dental plaque, and diabetes.

That doesn't mean it won't help—it means the studies so far haven't been strong enough to say one way or the other.

The evidence, ingredient by ingredient Holy Basil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Holy basil extract is generally well tolerated short-term in adults, though long-term safety data are limited. The most common side effects when taken by mouth are loose stools and nausea; a small number of trial participants experienced these.

When used topically as a mouthwash, it can leave a bitter taste. Pregnancy and breastfeeding are different stories.

Animal data raise concerns and human safety isn't established during pregnancy, so the facts advise against it. There's also not enough reliable safety information for breastfeeding, so it's best to avoid it then too.

If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Holy Basil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check with your doctor or pharmacist if you're on any of the following: blood thinners or antiplatelet drugs (like warfarin, aspirin, clopidogrel), diabetes medications (insulin, metformin, sulfonylureas, or others), or pentobarbital or other sedatives. Holy basil may intensify how these drugs work in your body.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Holy basil extract may help with anxiety, blood sugar, or respiratory symptoms, but the research isn't strong enough yet to say it will. If you take blood thinners, diabetes medications, or sedatives like pentobarbital, you'll want to check your exact drugs with your doctor or pharmacist before starting—the herb can amplify their effects.

Avoid it during pregnancy and while breastfeeding. For most other people, short-term use is generally well tolerated.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Holy Basil, straight from the product label.

Brand Oregon's Wild Harvest
Barcode (UPC) 706195173320
Net contents 2 fl. Oz.; 59 mL
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 175641
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Holy Basil by Oregon's Wild Harvest, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.5 mL
Maximum serving Sizes:
2.5 mL
Servings per container
24
UPC/BARCODE
706195173320
IngredientAmount% DV
Biodynamic & organic Holy Basil822 mg--

Other ingredients: Biodynamic and organic Alcohol, distilled Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

The tastiest and most dynamic Holy Basil.

Here's to the cycles of the moon. Here's to incredibly healthy soil and a wild and crazy approach to traditional farming.

Where everything old is new again.

Since 1994

May you live long and flourish

24 tasty servings

Alcohol Content: Not more than 70%.

Brand IP Statement(s)

Here's to Biodynamic herbs infused into a formula bursting with flavor and complexity designed to improve your stamina and support longevity.

Formulation

Allergen Information: Absolutely no dairy, wheat, gluten, peanuts, soy or corn allergens.

Certified Organic by Oregon Tilth

Non GMO

Precautions

Caution: Keep out of reach of children.

Do not take if pregnant or nursing. If taking medication consult a healthcare professional before use.

Discontinue use if unusual symptoms occur.

Do not exceed recommended dose.

General

R4

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic Certified Organic

Demeter Certified Biodynamic

OTCO

GF

Non GMO

Suggested/Recommended/Usage/Directions

Suggested Use: As an herbal tonic, take 2.5 mL (approx. three half-droppers) daily or as directed by your healthcare professional. Do not exceed recommended dose.

Shake well.

Storage

Store upright in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Holy Basil by Oregon's Wild Harvest label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Holy Basil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Holy Basil by Oregon's Wild Harvest

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2.5 mL Dosage formLiquid Servings per container24 Amounts shown are per serving.

Biodynamic & organic Holy Basil

Interacts with
212 drugs
822 mg per serving

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and p...

Biodynamic & organic Holy Basil monograph & interactions

Other (inactive) ingredients: Biodynamic and organic Alcohol, Distilled Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Holy Basil by Oregon's Wild Harvest Drug Interactions

Want to check YOUR meds against Holy Basil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
212Drugs
212 Moderate

Ingredients driving the most interactions

Biodynamic & organic Holy Basil 212

Individual Drug Interactions

The ingredients in Holy Basil interact with 212 drugs. Click any drug to see the details.

1 of the 1 ingredient in Holy Basil interact with drugs. Each result below shows which ingredient is responsible. Biodynamic & organic Holy Basil

Each ingredient & the kinds of drugs it affects

For each ingredient in Holy Basil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Biodynamic & organic Holy Basil3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
Biodynamic & organic Holy Basil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Holy Basil, from the product label.

Oregon's Wild Harvest

See all Oregon's Wild Harvest products
Name
Oregon's Wild Harvest
Street Address
1601 NE Hemlock Ave.
City
Redmond
State
OR
ZipCode
97756
Phone Number
1-800-316-6869
Web Address
oregonswildharvest.com
Pharmacist Counseling Corner

Holy Basil by Oregon's Wild Harvest: Common Questions

Does Holy Basil by Oregon's Wild Harvest interact with any medications?
Yes. Based on its ingredients, Holy Basil has a known interaction with 212 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Holy Basil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advise against it. Animal data raise concerns and human safety isn't established during pregnancy, so you should avoid it then. The same goes for breastfeeding—there isn't enough reliable information. Talk with your doctor or pharmacist about whether it's right for you.
What side effects might I experience?
Most people tolerate holy basil well short-term. The most common side effects are loose stools and nausea when taken by mouth—a small number of trial participants had these. If you use it as a mouthwash, you may notice a bitter taste.
Is this proven to work for anxiety or diabetes?
The evidence isn't established in the data we hold. There's insufficient reliable evidence to rate it for anxiety, diabetes, asthma, headache, or respiratory infections. That means the studies so far haven't been strong enough to confirm it works for those conditions.
What's actually in this product?
Just holy basil extract, dissolved in organic alcohol and distilled water. It's a one-ingredient liquid with no fillers beyond that carrier base.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Holy Basil is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Holy Basil label
Go deeper

The Full Monographs Behind Holy Basil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph →
Sources

Sources & How We Checked

Holy Basil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
  6. Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
  7. Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
  8. Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.

See these in context on the Holy Basil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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