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Dietary supplement

Inositol Ingredients & Drug Interactions

by SP Standard Process

Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Inositol is a dietary supplement by SP Standard Process with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Inositol by SP Standard Process

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: inositol, a naturally occurring compound your body makes and uses to help regulate blood sugar and support reproductive health. The rest is inactive ingredients — honey, water, and calcium stearate (a binding agent).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Heart and nervous system health.
  • We looked for evidence on: Anxiety, Depression, Panic disorder, Bipolar disorder, Obsessive-compulsive disorder (OCD), Post-traumatic stress disorder (PTSD) — and 4 related terms.
  • The strongest evidence on file: Inositol is rated "Possibly Effective" for Metabolic syndrome (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Ineffective" for Anxiety, Depression.
  • Also on file: Inositol is rated "Insufficient Reliable Evidence To Rate" for Bipolar disorder, Dyslipidemia, Hypertension, Insomnia.

Inositol is possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome. There's also possibly effective evidence for preterm labor prevention.

However, the evidence doesn't support its use for anxiety, diabetic nerve damage (neuropathy), or depression — these are rated possibly ineffective.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated at common doses. The most common side effects when taken by mouth are diarrhea, gas, and nausea — usually mild and digestive in nature.

When inositol was combined with omega-3 fatty acids in clinical research, a small number of children reported cold and allergy symptoms. There's one case report of a man with bipolar disorder hospitalized with manic symptoms after consuming an energy drink containing inositol, caffeine, taurine, and other ingredients over several days, but it's unclear whether inositol alone was responsible.

Safety data in pregnancy is not fully established. While inositol has been studied in pregnant people, use in pregnancy should only happen under medical supervision.

There is not enough reliable information on breastfeeding — talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product if you take antidiabetes drugs (insulin, metformin, sulfonylureas, and others that lower blood sugar). Inositol lowers blood glucose too, so combining them raises the risk of low blood sugar — your doctor may need to adjust your dose or monitor you more closely.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Inositol may help if you have PCOS, metabolic syndrome, or risk of preterm labor — talk with your doctor about whether it fits your situation. If you take any medication to lower blood sugar, check with your pharmacist or doctor first, since inositol can increase that effect.

Pregnant or breastfeeding — get personalized advice before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Inositol, straight from the product label.

Brand SP Standard Process
Barcode (UPC) 812122011105
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 340252
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Inositol by SP Standard Process, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
90
UPC/BARCODE
812122011105
IngredientAmount% DV
Inositol375 mg--

Other ingredients: Honey, Water, Calcium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Heart & nervous system health

GF (Gluten free)

FDA Statement of Identity

Dietary Supplement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested Use: One tablet per meal, or as directed.

General Statements

Whole Food Supplements Since 1929

See for yourself

Inositol by SP Standard Process label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Inositol by SP Standard Process

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Inositol

Interacts with
86 drugs
375 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions

Other (inactive) ingredients: Honey, Water, Calcium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Inositol by SP Standard Process Drug Interactions

Want to check YOUR meds against Inositol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Inositol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
The maker

Brand information

Manufacturer and brand details for Inositol, from the product label.

SP Standard Process

See all SP Standard Process products
Name
Standard Process Inc.
Street Address
PO Box 904
City
Palmyra
State
WI
ZipCode
53156
Pharmacist Counseling Corner

Inositol by SP Standard Process: Common Questions

Does Inositol by SP Standard Process interact with any medications?
Yes. Based on its ingredients, Inositol has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Inositol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is inositol supposed to do?
Inositol is a compound that helps regulate blood sugar and may support reproductive health. Research shows it's possibly effective for PCOS and metabolic syndrome, and possibly effective for reducing preterm labor risk. It hasn't been shown to help anxiety, nerve damage, or depression.
What are the most common side effects?
When taken by mouth, the most common side effects are mild: diarrhea, gas, and nausea. Inositol is generally well tolerated at typical doses.
Can I take this if I'm pregnant or breastfeeding?
Safety in pregnancy is not fully established, so use only under medical supervision if you're pregnant. There isn't enough reliable information on breastfeeding either — talk with your doctor or pharmacist for personalized advice before taking it.
Will this lower my blood sugar too much if I'm on diabetes medication?
Possibly. Inositol lowers blood glucose, and combining it with antidiabetes drugs raises the risk of low blood sugar. Your doctor or pharmacist can help decide if it's right for you and whether you need to monitor your blood sugar more closely or adjust your medication dose.
Does this product have any fillers or other inactive ingredients?
Yes — it contains honey, water, and calcium stearate (a binding agent used to hold the tablet together). The only active ingredient is inositol.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Inositol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Inositol label
Sources

Sources & How We Checked

Inositol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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