Lipo P.E.A. Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Lipo P.E.A. against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Lipo P.E.A. is a dietary supplement by Renue By Science with 1 active ingredient. Its ingredients are commonly taken for chronic pain, nerve (neuropathic) pain, inflammation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Lipo P.E.A. by Renue By Science
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Lipo P.E.A. has a single active ingredient: palmitoylethanolamide (PEA), a naturally occurring compound your body makes. The capsule also contains inactive ingredients — cellulose, sunflower lecithin, rice flour, and microcrystalline cellulose — which are fillers and binders that hold the capsule together.
Does it work?
Moderate evidence
The evidence for PEA is mixed and depends on what you're using it for. It's rated possibly effective for osteoarthritis, meaning there's some promising data but more research is needed to be sure.
For spinal cord injury, it's rated possibly ineffective. For carpal tunnel syndrome, migraine headache, autism spectrum disorder, and cannabis use disorder, the evidence we hold isn't solid enough to rate it either way.
How safe is it?
Well-documented data
PEA is generally well tolerated in studies, but long-term safety data are limited, so we can't say how it holds up over years of use. The most common side effect when taken by mouth is nausea, and a small number of people have reported mild, temporary digestive symptoms.
There isn't enough safety information to use PEA during pregnancy or while breastfeeding — talk with your doctor or pharmacist about whether it's right for you if you're pregnant, planning to become pregnant, or nursing.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredient in this product. Before you start, it's still a good idea to run your exact medications through the checker on this page or mention it to your pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Lipo P.E.A. may be worth considering if you're looking for support with osteoarthritis and want a supplement with no known drug interactions. If you're pregnant, breastfeeding, or have long-term use in mind, check with your pharmacist first, since safety data over extended periods are limited.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Lipo P.E.A., straight from the product label.
| Brand | Renue By Science |
|---|---|
| Barcode (UPC) | 656165996957 |
| Net contents | 90 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 22, 2024 |
| DSLD ID | 318996 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Lipo P.E.A. by Renue By Science, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Palmitoylethanolamide | 250 mg | -- |
Other ingredients: Cellulose, Sunflower Lecithin, Rice Flour, Microcrystalline Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Take one (1) capsule daily with or without food. May be taken with or without food.
Precautions
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using.
Do not use if safety seal is broken or missing.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Lipo P.E.A. is formulated with patented liposome technology designed to protect Palmitoylethanolamide through the gastrointestinal tract and bloodstream to reach cells and tissues throughout the body intact.
This product is manufactured in the United States at a FDA registered facility under strict GMP standards.
Liposomal capsules
No artificial colors, flavors or preservatives. Non-GMO.
Suitable for vegans.
Seals/Symbols
GMP Good Manufacturing Practice Certified
Formula
Lipo P.E.A. (Palmitoylethanolamide) Powdered liposomes
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Lipo P.E.A. by Renue By Science label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Lipo P.E.A. by Renue By Science
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Palmitoylethanolamide
No knowninteractions
Palmitoylethanolamide (PEA) is a fat-like molecule made naturally in the body and studied mainly for pain and inflammation. Some research suggests it...
Palmitoylethanolamide monograph & interactionsOther (inactive) ingredients: Cellulose, Sunflower Lecithin, Rice Flour, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.
Lipo P.E.A. by Renue By Science Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Lipo P.E.A.. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Lipo P.E.A., from the product label.
Renue By Science
See all Renue By Science products- Name
- Renue By Science
- City
- Jacksonville
- State
- FL
- ZipCode
- 32204
- Phone Number
- 1-800-810-1935
- Web Address
- renuebyscience.com
Lipo P.E.A. by Renue By Science: Common Questions
Does Lipo P.E.A. by Renue By Science interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Lipo P.E.A. if I'm pregnant or breastfeeding?
What is palmitoylethanolamide (PEA)?
Does Lipo P.E.A. actually work for arthritis?
What side effects should I watch for?
Is there anything in this product besides the active ingredient?
Will this interact with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Lipo P.E.A. is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Lipo P.E.A.’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Lipo P.E.A.'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Palmitoylethanolamide (pea) 4 references
- Indraccolo U, Barbieri F. Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations. Eur J Obstet Gynecol Reprod Biol. 2010 May;150(1):76-9. PubMed
- Murina F, Graziottin A, Felice R, Radici G, Tognocchi C. Vestibulodynia: synergy between palmitoylethanolamide + transpolydatin and transcutaneous electrical nerve stimulation. J Low Genit Tract Dis. 2013 Apr;17(2):111-6.
- Papetti L, Sforza G, Tullo G, et al. Tolerability of palmitoylethanolamide in a pediatric population suffering from migraine: A pilot study. Pain Res Manag 2020;2020:3938640. PubMed
- Visse K, Blome C, Phan NQ, Augustin M, Ständer S. Efficacy of body lotion containing N-palmitoylethanolamine in subjects with chronic pruritus due to dry skin: A dermatocosmetic study. Acta Derm Venereol. 2017;97(5):639-641. PubMed
See these in context on the Palmitoylethanolamide (pea) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC