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Dietary supplement

Liposomal Strontium Ingredients & Drug Interactions

by Codeage

Capsule Category: Single Vitamin And Mineral
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Liposomal Strontium is a dietary supplement by Codeage with 2 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis, reducing fracture risk, tooth sensitivity (in some toothpastes).Based on those ingredients, 103 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Strontium, Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Liposomal Strontium by Codeage

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Strontium” is listed as a grouped ingredient — the label gives one combined amount (680 mg) without saying how much of each component you get.

This product contains 2 active ingredients. Strontium citrate is a form of the mineral strontium, which your bones take up and may help strengthen them.

Vitamin K2 is a fat-soluble vitamin that plays a role in bone metabolism and blood clotting. The capsules also contain inactive ingredients — methylcellulose, microcrystalline cellulose, sunflower oil, and lecithin — which are excipients that help form and stabilize the supplement.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Bone health and osteoporosis support.
  • We looked for evidence on: Osteoporosis, Fractures, Bone density, Bone strength.
  • The strongest evidence on file: Strontium is rated "Likely Effective" for Osteoporosis (Natural Medicines).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.
  • Also on file: Strontium is rated "Insufficient Reliable Evidence To Rate" for Fractures.

For strontium citrate: the evidence supports its use for dental sensitivity and bone pain from cancer spread (metastases). It's likely effective for osteoporosis and possibly effective for osteoarthritis and prostate cancer.

For vitamin K2: the evidence supports its role in treating clotting factor deficiency and certain bleeding disorders, and it's possibly effective for osteoporosis. However, the facts we hold don't establish broader roles for this ingredient.

The evidence, ingredient by ingredient Strontium Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Strontium has been linked to serious heart and clotting risks — the data shows it raises the risk of blood clots (venous thromboembolism and pulmonary embolism) by about 50% and heart attack risk by about 1.6 times in people with osteoporosis. Most common side effects are mild: atopic dermatitis, diarrhea, headache, and nausea.

Rare serious effects include heart attack and blood clots. Vitamin K2 is generally well tolerated; mild gastrointestinal upset (nausea, diarrhea, stomach upset) is the most common adverse effect.

Strontium is not recommended during pregnancy and should be avoided while breastfeeding. Vitamin K2 is considered likely safe in pregnancy but check with your doctor before taking it as a supplement while breastfeeding.

Side effects, ingredient by ingredient Strontium Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Vitamin K, Strontium.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 103 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check if you're on warfarin or other blood thinners — vitamin K2 can interfere with how they work. Strontium also requires caution if you take estrogens, androgens (like testosterone), antacids, quinolone antibiotics (like ciprofloxacin), or tetracycline antibiotics (like doxycycline).

If you take any of these, run them through the checker on this page or ask us first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you have osteoporosis or bone pain and don't take warfarin or hormone treatments, a conversation with your pharmacist about strontium makes sense — but be aware of its documented heart and clotting risks. Anyone on warfarin, estrogens, androgens, antacids, or certain antibiotics should check with us before starting.

Pregnancy and breastfeeding require a talk with your doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liposomal Strontium, straight from the product label.

Brand Codeage
Barcode (UPC) 850049609395
Net contents 90 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 333433
Product type Single Vitamin And Mineral
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liposomal Strontium by Codeage, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
850049609395
IngredientAmount% DV
Strontium680 mg--
Strontium Citrate2.2 Gram(s)--
Vitamin K2100 mcg--

Other ingredients: Methylcellulose, Microcrystalline Cellulose, Sunflower Oil, Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Strontium Citrate Vitamin K2 Essential Phospholipids

Strontium Citrate - Vitamin K2 Phospholipid complex

Formulation

Non-GMO Soy-Free Dairy-Free Gluten-Free

cGMP Certified Manufacturing

Bioavailable

Brand IP Statement(s)

Feel different.

Copyright Codeage LLC. All rights reserved.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Adults take 3 capsules daily, or as recommended by your healthcare practitioner, with 8 ounces of water or your favorite beverage. May be taken with or without food. For best absorption take strontium at least two hours apart from calcium.

Precautions

Caution: Do not exceed recommended dose. Discontinue use two weeks prior to surgery.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Please use caution if you have allergies or sensitivities to any of the listed ingredients.

Not intended for those under the age of 18. Keep out of reach of children and pets.

Do not use if product has been opened or tampered with in any way.

General Statements

Please Recycle Bottle & cap Please take off the label Questions? Codeage.com Scan for info

Eternal

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a cool, dry place.

See for yourself

Liposomal Strontium by Codeage label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Liposomal Strontium by Codeage

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Strontium

Interacts with
101 drugs
680 mg per serving

Strontium is a mineral that has been studied mainly for bone health and osteoporosis. The prescription form (strontium ranelate) showed benefit for fr...

Strontium monograph & interactions

Vitamin K2

Interacts with
2 drugs
100 mcg per serving Form: Menaquinone-7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Methylcellulose, Microcrystalline Cellulose, Sunflower Oil, Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liposomal Strontium by Codeage Drug Interactions

Want to check YOUR meds against Liposomal Strontium?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
103Drugs
2 Major 101 Moderate

Ingredients driving the most interactions

Strontium 101

Each ingredient & the kinds of drugs it affects

For each ingredient in Liposomal Strontium with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Strontium5 drug types · 101 drugs

Androgens

Theoretically, androgens might reduce the excretion of strontium, potentially increasing its effects and adverse effects.
A small clinical study suggests that treatment with androgens such as testosterone, nandrolone, oxandrolone, and oxymetholone for 5-6 weeks might decrease urinary strontium excretion. The clinical significance of this interaction is unknown.

Likelihood Possible Evidence D
Antacids

Antacids can reduce the absorption of strontium, potentially decreasing its effectiveness.
Aluminum hydroxide and magnesium hydroxide can reduce absorption of strontium ranelate by 20% to 25%. Calcium can reduce its absorption to 60% to 70%. Avoid taking antacids within 2 hours of a dose of strontium ranelate. This interaction has also been reported with orally-administered radioactive strontium-85. It will likely also occur with other forms of strontium.

Likelihood Probable Evidence C
Estrogens

Theoretically, estrogens might reduce the excretion of strontium, potentially increasing its effects and adverse effects.
A small clinical study suggests that treatment with estrogens for 5-6 weeks might decrease urinary strontium excretion. The clinical significance of this interaction is unknown.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, strontium might decrease the absorption of quinolone antibiotics.
Strontium is a divalent cation with similar properties to calcium. It is likely to form complexes with quinolones in the gastrointestinal (GI) tract, preventing absorption of the antibiotic. Recommend taking strontium supplements at least 2 hours before or after quinolones to avoid an interaction.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, strontium might decrease the absorption of tetracycline antibiotics.
Strontium is a divalent cation with similar properties to calcium. It is likely to form complexes with tetracyclines in the gastrointestinal (GI) tract, preventing absorption of the antibiotic. Recommend taking strontium supplements at least 2 hours before or after tetracyclines to avoid an interaction.

Likelihood Probable Evidence D

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Liposomal Strontium, from the product label.

Codeage

See all Codeage products
Name
Codeage LLC
Street Address
5628 Washington Blvd
City
Los Angeles
State
CA
ZipCode
90016
Web Address
www.codeage.com
Pharmacist Counseling Corner

Liposomal Strontium by Codeage: Common Questions

Does Liposomal Strontium by Codeage interact with any medications?
Yes. Based on its ingredients, Liposomal Strontium has a known interaction with 103 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Liposomal Strontium contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does strontium really help osteoporosis?
The evidence we have supports that it's likely effective for osteoporosis. That said, be aware that strontium has been linked to serious risks — a higher chance of blood clots and heart attack, especially in people with osteoporosis — so talk with your doctor about whether it's the right choice for you.
What are the most common side effects?
With strontium, expect mild effects like diarrhea, nausea, headache, and skin irritation. Vitamin K2 can also cause mild stomach upset, nausea, and diarrhea. Serious side effects are rare but have been reported.
Can I take this if I'm pregnant?
The safety data advises against strontium during pregnancy. Vitamin K2 is considered likely safe in pregnancy, but you should talk with your doctor or pharmacist before adding any supplement while you're pregnant — it's a personal medical decision.
Can I take this while breastfeeding?
There isn't enough safety data on strontium during breastfeeding, so it's best to avoid it. Vitamin K2 has limited safety information for breastfeeding as well. Talk with your doctor or pharmacist for personalized advice.
Should I avoid antacids while taking this?
Yes. Antacids — especially ones with calcium, aluminum, or magnesium — can cut strontium absorption by 20% to 70%. Try to take this supplement at least 2 hours before or after any antacid.
What's the difference between the two ingredients in this product?
Strontium citrate is a mineral that your bones absorb and may help strengthen them. Vitamin K2 is a vitamin that supports bone metabolism and blood clotting. Together, they're intended to support bone health, but they work through different mechanisms.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Liposomal Strontium is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liposomal Strontium label
Sources

Sources & How We Checked

Liposomal Strontium's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 33 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Strontium 22 references
  1. Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
  2. Meunier PJ, Roux C, Seeman E, et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 2004;350:459-68.. PubMed
  3. El-Hajj Fuleihan G. Strontium ranelate--a novel therapy for osteoporosis or a permutation of the same? N Engl J Med 2004;350:504-6. PubMed
  4. Verberckmoes SC, De Broe ME, D'Haese PC. Dose-dependent effects of strontium on osteoblast function and mineralization. Kidney Int 2003;64:534-43. . PubMed
  5. Meunier PJ, Slosman DO, Delmas PD, et al. Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial. J Clin Endocrinol Metab 2002;87:2060-6.. DOI
  6. Brandi ML. New treatment strategies: ipriflavone, strontium, vitamin D metabolites and analogs. Am J Med 1993;95:69S-74S. . PubMed
  7. Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
  8. Metastron prescribing information. Medi-Physics, Inc., Amersham Healthcare, Arlington Heights, IL, 1998. http://www.cancerpaintherapy.com/METATECHPAGE.htm. (Accessed 13 March 2004).
  9. Protelos European Summary of Product Characteristics. Les Laboratoires Servier, 2006. Available at: www.servier.com/pro/osteoporose/protelos/protelos_spc.asp. (Accessed 01 August 2006).
  10. US Department of Health and Human Services, Public Health Service. Agency for Toxic Substances and Disease Registry. Toxicological profile for strontium. April 2004. Available at: www.atsdr.cdc.gov/toxprofiles/tp159.pdf. (Accessed 8 August 2006).
  11. Apostolidis N, Paradellis T, Karydas A, et al. Calcium and strontium metabolic studies in patients on CAPD. Perit Dial Int 1998;18:410-4. DOI
  12. Ozgur S, Sumer H, Kocoglu G. Rickets and soil strontium. Arch Dis Child 1996;75:524-6. PubMed
  13. Schrooten I, Elseviers MM, Lamberts LV, et al. Increased serum strontium levels in dialysis patients: an epidemiological survey. Kidney Int 1999;56:1886-92. PubMed
  14. D'Haese PC, Couttenye MM, Lamberts LV, et al. Aluminum, iron, lead, cadmium, copper, zinc, chromium, magnesium, strontium, and calcium content in bone of end-stage renal failure patients. Clin Chem 1999;45:1548-56. DOI
  15. Pennington JA, Jones JW. Molybdenum, nickel, cobalt, vanadium, and strontium in total diets. J Am Diet Assoc 1987;87:1644-50. DOI
  16. O'Donnell S, Cranney A, Wells GA, et al. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Cochrane Musculoskeletal Group. Cochrane Database Syst Rev 2006;(4):CD005326. PubMed
  17. Protelos European Public Assessment Report, Scientific Discussion. European Medicines Agency, 2005. Available at: www.emea.eu.int/humandocs/Humans/EPAR/protelos/protelos.htm. (Accessed 10 October 2006).
  18. Rousselet F, El Solh N, Maurat JP, et al. Strontium and calcium metabolism. Interaction of strontium and vitamin D. C R Seances Soc Biol Fil 1975;169:322-9.
  19. O'Donnell, S., Cranney, A., Wells, G. A., Adachi, J. D., and Reginster, J. Y. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Cochrane.Database.Syst.Rev. 2006;3:CD005326. PubMed
  20. Rizzoli R, Chapurlat RD, Laroche JM, et al. Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis. Results of a 2-year study. Osteoporosis Int. 2012. 23(1):305-315. doi: 10.1007/s00198-011-1758-z. PubMed
  21. Reginster JY, Kaufman JM, Goemaere S, et al. Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis. Osteoporos Int. 2012;23(3):1115-1122. doi: 10.1007/s00198-011-1847-z. PubMed
  22. Protos [Product Information]. Available at: http://www.guildlink.com.au/gc/ws/servier/pi.cfm?product=sepproto. Accessed May 1, 2018.

See these in context on the Strontium monograph →

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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