Interactions on record — worth a quick check against your medications. Based on 4 of 7 ingredients. Check your meds →
Dietary supplement

Mdrive Omega Ingredients & Drug Interactions

by DreamBrands

Mdrive Omega label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Mdrive Omega against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Mdrive Omega is a dietary supplement by DreamBrands with 7 active ingredients. Its ingredients are commonly taken for brain and cognitive health, eye and vision health, fetal and infant development.Based on those ingredients, 520 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Omega-3, Fish Oil, Flaxseed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Mdrive Omega by DreamBrands

Ask about any prescription or over-the-counter medication and we check it for interactions with Mdrive Omega by DreamBrands — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Mdrive Omega by DreamBrands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 11 active ingredients.
  • “Omega-3” is listed as a grouped ingredient — the label gives one combined amount (451 mg) without saying how much of each component you get.
  • “Omega-6” is listed as a grouped ingredient — the label gives one combined amount (98 mg) without saying how much of each component you get.
  • “Omega-3-6-9 Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,200 mg) without saying how much of each component you get.

Mdrive Omega is an 11-ingredient softgel containing three active oils — fish oil, flaxseed oil, and borage oil — plus seven individual fatty acid components: eicosapentaenoic acid, docosahexaenoic acid, gamma-linolenic acid, linoleic acid, alpha-linolenic acid, polyunsaturated fat, and other fatty acids, along with omega-9. The three oils are the main sources of omega-3, omega-6, and omega-9 fatty acids.

The softgels also contain gelatin, glycerin, purified water, and mixed tocopherols as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: heart and brain health support.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Angina, Atherosclerosis, Cardiovascular disease (CVD), Cerebrovascular disease — and 4 related terms.
  • The closest evidence on file: Fish Oil is rated "Possibly Ineffective" for Unstable angina (Natural Medicines).
  • Also on file: Fish Oil is rated "Possibly Ineffective" for Atherosclerosis, Cerebrovascular disease, Cognitive function, Angina.
  • Also on file: Borage is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD).

Fish oil in this product is rated effective for high triglycerides (hypertriglyceridemia) and possibly effective for heart failure, wasting from illness (cachexia), kidney damage from the drug cyclosporine, and nonalcoholic fatty liver disease. Flaxseed oil, however, shows limited promise: the data rates it possibly ineffective for obesity, rheumatoid arthritis, bipolar disorder, and high cholesterol.

Borage oil's effectiveness is uncertain — the evidence we hold is either insufficient to rate it (for ADHD and acute respiratory distress syndrome) or rates it possibly ineffective (for eczema).

The evidence, ingredient by ingredient Docosahexaenoic Acid (dha) Fish Oil Flaxseed Oil Borage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Fish oil is generally well tolerated at typical supplement doses. The most common side effects are fishy aftertaste, bad breath, heartburn, abdominal pain, loose stools, and nausea.

At doses of 3 grams or more daily, fish oil may thin blood slightly and, very rarely, increase the risk of irregular heartbeats (atrial fibrillation) or bleeding. Flaxseed oil is generally well tolerated but has limited safety data; a small percentage of users report loose stools or diarrhea at higher doses.

Borage seed oil is well tolerated when it's certified free of liver-toxic alkaloids, but some borage plant parts contain these alkaloids and can damage the liver. For pregnancy and breastfeeding: fish oil carries conflicting ratings (likely safe for some uses but possibly unsafe for others), so discuss it with your doctor; flaxseed oil is possibly safe in pregnancy but has limited lactation data; borage oil is rated likely unsafe in pregnancy and should be avoided.

Side effects, ingredient by ingredient Docosahexaenoic Acid (dha) Fish Oil Flaxseed Oil Borage

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Borage, Flaxseed Oil, Fish Oil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 435 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Mdrive Omega, double-check with your doctor or pharmacist if you're on immunosuppressants (tacrolimus, cyclosporine, sirolimus — Moderate risk), blood pressure medications (Moderate risk), blood thinners or antiplatelet drugs like warfarin or aspirin (Minor to Moderate risk), birth control pills, the cholesterol drug ezetimibe, the weight-loss drug orlistat, or antipsychotic medications (phenothiazines). These interactions are documented in the fish oil, flaxseed oil, and borage oil components.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Mdrive Omega is most suitable if you're looking to raise omega-3 intake and have no immunosuppressant medications, blood pressure drugs, blood thinners, or certain other prescriptions. If you take tacrolimus, cyclosporine, sirolimus, warfarin, birth control pills, ezetimibe, orlistat, or any antipsychotic, check with your doctor or pharmacist before starting — the interactions are real and may require dose adjustments or timing changes.

Pregnant or breastfeeding women should discuss this product with their healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mdrive Omega, straight from the product label.

Brand DreamBrands
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 307871
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mdrive Omega by DreamBrands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
IngredientAmount% DV
Calories10 Calorie(s)--
Eicosapentaenoic Acid0 NP--
Docosahexaenoic Acid0 NP--
Gamma-Linolenic Acid0 NP--
Cholesterol2 mg1%
Total Fat1 Gram(s)1%
Linoleic Acid0 NP--
Alpha-Linolenic Acid0 NP--
Polyunsaturated Fat1 Gram(s)--
Other Fatty Acids0 NP--
Omega-988 mg--
Omega-3451 mg--
Fish Oil0 NP--
Flaxseed Oil0 NP--
Omega-698 mg--
Omega-3-6-9 Proprietary Blend1200 mg--
Borage Oil0 NP--

Other ingredients: Gelatin, Glycerin, Water, Purified, Mixed Tocopherols

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Omega 3-6-9 1200mg From fish, borage & flaxseed oil

Heart Health Fish oil is a dietary source of fatty acids that can help support heart and brain health. Skin & Joint support Borage oil contains GLA, an Omega 6 fatty acid to support healthy skin and joints. Cardio Care Flaxseed Oil contains a plant-based ALA, which can support cardiovascular and overall health.

The only everyday omega for driven men

MDrive Omega Powered by a balanced blend of Omega 3, 6 and 9 from fish, borage and flaxseed oil. Support your heart and other vital organs.

FDA Statement of Identity

Dietary Supplement

General Statements

Don't let age beat you. Take your Omega and refind your prime with Mdrive. 60 Day Guarantee To ensure 100% satisfaction we offer a money back guarantee for 60 days from the date of purchase. Call 1-888-300-9181 for details. Office hours are 9am-5pm (AZ time) M-F.

Brand IP Statement(s)

Mdrive is a registered trademark of DreamBrands, Inc. Copyright 2004-2021

Precautions

Adverse events may be reported to this address.

Contains highly refined fish oil (Anchovy and/or Sardine). If you have an allergic reaction please discontinue use and consult a physician.

Cautions: Keep out of reach of children. Not intended for persons under 18.

Do not use if inner seal is torn.

Consult a physician if you are taking any medications or have any medical conditions. Do not use if you may become pregnant, are pregnant or nursing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 softgel, once or twice daily.

Storage

Store at room temperature.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Mdrive Omega by DreamBrands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Mdrive Omega label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Mdrive Omega by DreamBrands

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Omega-9

88 mg per serving Form: Oleic Acid

Omega-3

Interacts with
375 drugs
451 mg per serving

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and gen...

Omega-3 monograph & interactions
  • › Eicosapentaenoic Acid
  • › Docosahexaenoic Acid
  • › Alpha-Linolenic Acid
  • › Other Fatty Acids

Omega-6

98 mg per serving
  • › Gamma-Linolenic Acid
  • › Linoleic Acid

Omega-3-6-9 Proprietary Blend

1200 mg per serving

Other (inactive) ingredients: Gelatin, Glycerin, Water, Purified, Mixed Tocopherols. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mdrive Omega by DreamBrands Drug Interactions

Want to check YOUR meds against Mdrive Omega?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
520Drugs
517 Moderate 3 Minor

Ingredients driving the most interactions

Omega-3 375
Fish Oil 327
Flaxseed Oil 293
Borage Oil 226

Individual Drug Interactions

The ingredients in Mdrive Omega interact with 520 drugs. Click any drug to see the details.

4 of the 7 ingredients in Mdrive Omega interact with drugs. Each result below shows which ingredient is responsible. Omega-3 Fish Oil Flaxseed Oil Borage Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Mdrive Omega with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Omega-33 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Although some clinical evidence suggests that DHA might reduce collagen-stimulated platelet aggregation and thromboxane release, most clinical evidence suggests that DHA alone does not affect blood clotting. However, theoretically, when given in combination with EPA as fish oil, concomitant use with anticoagulant or antiplatelet drugs (including aspirin) might increase risk of bleeding.

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Fish oils containing DHA can lower blood pressure and might have additive effects in patients treated with antihypertensives; use with caution.

Likelihood Probable Evidence B
Omega-3 full monograph & interactions

Fish Oil9 drug types · 327 drugs

Antihypertensive Drugs

Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Clinical evidence indicates that fish oils can modestly lower blood pressure and might have additive effects in patients treated with antihypertensives.

Likelihood Probable Evidence B
Contraceptive Drugs

Theoretically, taking fish oil with contraceptive drugs might decrease the triglyceride-lowering effects of fish oil.
There is some evidence that contraceptive drugs might interfere with the triglyceride lowering effects of fish oils.

Likelihood Probable Evidence B
Cyclosporine (Neoral, Sandimmune)

Taking fish oil with cyclosporine might increase levels and adverse effects of cyclosporine.
In kidney transplant recipients on a general immunosuppressive regimen, taking omega-3 fatty acids daily seems to increase peak blood levels of cyclosporine when compared with placebo. This increase was as much as 20% after one month. However, the area under the curve was not significantly affected.

Likelihood Probable Evidence B
Orlistat (Xenical, Alli)

Theoretically, taking fish oil with orlistat might decrease the absorption of fish oil fatty acids.
Orlistat binds lipase in the gastrointestinal tract and reduces fat absorption. Theoretically, taking fish oil with orlistat might decrease absorption of fish oil fatty acids. To avoid this potential interaction, recommend separating administration of orlistat and fish oil by at least 2 hours.

Likelihood Probable Evidence D
Sirolimus (Rapamune)

Taking fish oil with sirolimus might increase levels and adverse effects of sirolimus.
Pharmacokinetic research shows that omega-3 fatty acids increase exposure to sirolimus in kidney transplant patients on a calcineurin inhibitor-free immunosuppressive regimen. A 25% dose reduction in sirolimus was required to keep patients within the expected trough-concentration window. Researchers hypothesize that this may be due to inhibition of cytochrome P450 3A4 (CYP3A4) by fish oil, although this has not been confirmed in clinical research.

Likelihood Probable Evidence B
Tacrolimus (Prograf)

Taking fish oil with tacrolimus might increase levels and adverse effects of tacrolimus.
In a small group of patients, taking fish oil 2.6 grams (Omacor) daily for 4 weeks increased the 8-hour area under the curve of tacrolimus by 25% when compared with baseline. Peak levels were increased by approximately 22%. Researchers hypothesize that this may be due either to an increase in bioavailability or to inhibition of cytochrome P450 3A4 (CYP3A4) by fish oil, although this has not been confirmed in clinical research.

Likelihood Probable Evidence B
Anticoagulant/Antiplatelet Drugs

Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, evidence is conflicting.
While fish oil may not be a potent inhibitor of platelet function, high doses of fish oil might have antiplatelet effects. Theoretically, concomitant use of fish oil with anticoagulant or antiplatelet drugs may increase the risk of bleeding. However, the most rigorous research shows that short-term doses of fish oil 10 grams daily or long-term doses of 1.5 grams daily for up to 52 weeks does not increase the risk of bleeding or affect coagulation parameters in chronically ill and vulnerable patients. Other controlled research shows that fish oil does not affect platelet function or increase the risk of bleeding. Some research even suggests that perioperative fish oil use decreases bleeding risk. Some research suggests fish oil does not have additive antiplatelet effects when combined with aspirin, but other clinical evidence suggests that adding fish oil to low-dose aspirin treatment increases antiplatelet effects in patients who are aspirin-resistant. Also, some clinical research seems to show that fish oil has additive antiplatelet effects when used with aspirin and clopidogrel compared to aspirin and clopidogrel alone.

Likelihood Unlikely Evidence B
Platinum Agents

Theoretically, taking fish oil with platinum agents can cause resistance to platinum agents, potentially decreasing their effectiveness.
Platinum-induced fatty acids (PIFAs) are fatty acids secreted from human and mouse stem cells when exposed to platinum-based chemotherapy. Animal research suggests that PIFAs cause resistance to chemotherapy by stimulating lysophospholipid production in the spleen, which interferes with the DNA damage caused by certain chemotherapy drugs. One PIFA, known as 16:4(n-3), has been found in both raw fish and some commercially available fish oil products. Mackerel and herring have high PIFA concentrations, while salmon and tuna have low PIFA concentrations. Levels of PIFA in commercial fish oil products ranged from 0.2- 5.7 microMol. Animal research shows that PIFA-containing fish oil products cause resistance to cisplatin, fluorouracil, irinotecan, and oxaliplatin. It is unclear if all commercially available fish oil products contain PIFAs. Additionally, it is argued that levels of PIFA found in some fish oil products are too low to be of clinical concern. Furthermore, a lack of chemotherapy resistance in countries with high fish intake, such as Greenland, Japan, and Norway, suggest that this interaction may not be clinically significant.

Likelihood Unlikely Evidence D
Warfarin (Coumadin)

Fish oil may have antiplatelet effects and might increase the risk of bleeding if used with warfarin.
Fish oil has antiplatelet effects at high doses. Case reports show elevated INR in patients taking warfarin and fish oil 1-2 grams daily. However, some clinical research shows that taking fish oil 3-6 grams daily does not significantly increase INR in patients taking warfarin.

Likelihood Unlikely Evidence B
Fish Oil full monograph & interactions

Flaxseed Oil3 drug types · 293 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Small clinical studies show that consuming flaxseed oil might decrease platelet aggregation and increase bleeding time.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Some clinical evidence suggests that long-term consumption of flaxseed oil can modestly lower systolic and diastolic blood pressure, while other clinical research shows no effect.

Likelihood Possible Evidence D
Ezetimibe (Zetia)

Concomitant use of flaxseed oil and ezetimibe reduces the absorption of alpha-linolenic acid from flaxseed oil.
In one clinical study, concomitant consumption of ezetimibe 10 mg daily with flaxseed oil 2 grams providing 1 gram of alpha-linolenic acid daily blocked the absorption of alpha-linolenic acid, resulting in an overall reduction in alpha-linolenic plasma levels from baseline.

Likelihood Probable Evidence B
Flaxseed Oil full monograph & interactions

Borage Oil3 drug types · 226 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In healthy individuals, borage seed oil supplementation does not seem to affect platelet aggregation. However, gamma-linolenic acid, a constituent of borage seed oil, seems to decrease platelet aggregation by 45% and increase the risk of bleeding by 40% in animal and clinical research.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Inducers

Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Although borage seed oil contains little to no PAs, some borage plant parts, such as the leaf, flower, and seed, can contain hepatotoxic PAs. Hepatotoxic PAs are substrates of CYP3A4, which converts these chemicals into toxic metabolites. Tell patients to avoid borage preparations that are not certified and labeled as hepatotoxic PA-free.

Likelihood Possible Evidence D
Phenothiazines

Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Borage seed oil contains gamma-linolenic acid (GLA). There is concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines. This is based on limited data from two reports published in the 1980s. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with evening primrose, another source of GLA. However, none experienced an actual seizure. In the other report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily was added. One of these patients had a prior history of seizures. It is unclear whether evening primrose had any additive epileptogenic effects with the phenothiazines, but there is no evidence that taking GLA-containing supplements alone can cause seizures.

Likelihood Possible Evidence D
Borage Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Mdrive Omega, from the product label.

DreamBrands

See all DreamBrands products
Name
DreamBrands, Inc.
Street Address
11645 N Cave Creek Rd
City
Phoenix
State
AZ
ZipCode
85020
Phone Number
1-888-300-9181
Web Address
MdriveForMen.com
Pharmacist Counseling Corner

Mdrive Omega by DreamBrands: Common Questions

Does Mdrive Omega by DreamBrands interact with any medications?
Yes. Based on its ingredients, Mdrive Omega has a known interaction with 520 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mdrive Omega contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is fish oil actually used for?
Fish oil is well established for lowering high triglycerides. It's also studied for heart failure, wasting from serious illness, kidney damage from certain drugs, and fatty liver disease, though the evidence for those is less certain.
Can I take this if I'm pregnant or breastfeeding?
It depends on which ingredient you're asking about. Fish oil has conflicting safety data (some uses are likely safe, others possibly unsafe), flaxseed oil is possibly safe in pregnancy but has limited lactation data, and borage oil is not advised in pregnancy. Talk with your doctor or pharmacist about what's right for your situation.
What are the most common side effects I might notice?
Most commonly, fish oil causes fishy aftertaste, bad breath, heartburn, or loose stools. Flaxseed and borage oils may cause bloating, belching, or loose stools in some users. These are usually mild and tolerable.
Do I need to worry about bleeding if I take this with aspirin or warfarin?
Fish oil, flaxseed oil, and borage oil can all theoretically increase bleeding risk when combined with blood thinners or antiplatelet drugs. The risk at typical supplement doses is low (rated Minor), but higher doses raise concern. Talk to your doctor before combining them.
Is there anything special about the borage oil in this product?
Borage seed oil is generally safe, but make sure it's certified free of pyrrolizidine alkaloids — toxic compounds found in some borage plant parts. The product facts don't specify whether this one is certified PA-free, so ask the manufacturer or your pharmacist.
Will this help me lose weight or manage my cholesterol?
Fish oil is effective for high triglycerides specifically. Flaxseed oil, which is in this product, is rated possibly ineffective for both obesity and high cholesterol. Borage oil's effects on weight and cholesterol aren't established in the data we hold.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mdrive Omega label
Go deeper

The Full Monographs Behind Mdrive Omega’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Docosahexaenoic Acid (dha)

Interacts with 375 drugs

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and generally well tolerated, with the stronges...

Read the full Docosahexaenoic Acid (dha) monograph → Herb & supplement monograph

Fish Oil

Interacts with 327 drugs

Fish oil provides omega-3 fatty acids (EPA and DHA) that are best known for lowering high triglyceride levels. The evidence for other heart and health benefits is mixed, and it is generally...

Read the full Fish Oil monograph → Herb & supplement monograph

Flaxseed Oil

Interacts with 293 drugs

Flaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil. It may help support heart health and provide healthy...

Read the full Flaxseed Oil monograph → Herb & supplement monograph

Borage

Interacts with 226 drugs

Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arthritis with mixed results. The plant's le...

Read the full Borage monograph →
Sources

Sources & How We Checked

Mdrive Omega's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 238 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Docosahexaenoic Acid (dha) 49 references
  1. Akedo I, Ishikawa H, Nakamura T, et al. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (abstract). Jpn J Clin Oncol PubMed
  2. Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
  3. Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
  4. Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
  5. Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
  6. Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
  7. FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
  8. Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
  9. Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
  10. Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
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See these in context on the Docosahexaenoic Acid (dha) monograph →

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Flaxseed Oil 21 references
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Borage 11 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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