Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Myo & D-Chiro Inositol Ingredients & Drug Interactions

by ForestLeaf

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Myo & D-Chiro Inositol is a dietary supplement by ForestLeaf with 3 active ingredients. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Myo-Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Myo & D-Chiro Inositol by ForestLeaf

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This capsule contains 3 active ingredients: myo-inositol and D-chiro inositol — two naturally occurring forms of a compound your body makes and uses in cell signaling — plus folate, a B vitamin. The capsule itself is made from vegetable cellulose, and the powder inside also contains microcrystalline cellulose, magnesium stearate, and silicon dioxide as binders and flow agents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: promote female fertility and reproductive health.
  • We looked for evidence on: Polycystic ovary syndrome (PCOS), Infertility, Metabolic syndrome, Anxiety, Depression, Diabetes — and 2 related terms.
  • The strongest evidence on file: Inositol is rated "Possibly Effective" for Polycystic ovary syndrome (PCOS) (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Effective" for Metabolic syndrome.
  • Also on file: Inositol is rated "Possibly Ineffective" for Anxiety, Depression.

The inositol forms show possibly effective evidence for polycystic ovary syndrome (PCOS), metabolic syndrome, and preterm labor. For anxiety, diabetic nerve pain (neuropathy), and depression, the evidence rates as possibly ineffective.

The effectiveness of folate in this product isn't established in the data we hold.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both inositol forms are generally well tolerated at common doses, with digestive side effects — diarrhea, gas, and nausea — being the most common. One small number of children in a trial taking inositol with omega-3 fatty acids reported cold and allergy symptoms.

Pregnancy safety data shows inositol as possibly safe, but it has been studied only with medical supervision — there isn't enough reliable information yet, so use only under your doctor's guidance if you're pregnant or planning to be. We don't have lactation safety data on file for these ingredients.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you're on any antidiabetes medication — insulin, metformin, sulfonylureas, GLP-1 agonists, or any other blood sugar drug. The inositol in this product lowers blood glucose, so there's a Moderate risk of your blood sugar dropping too low when combined with these drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with PCOS, metabolic syndrome, or preterm labor, depending on what the evidence applies to in your case. If you take diabetes medication, you'll want to check this with your doctor or pharmacist first, because the inositol could lower your blood sugar further.

Talk with your own healthcare provider before starting — they can weigh the benefit against your individual situation and any medications you take.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Myo & D-Chiro Inositol, straight from the product label.

Brand ForestLeaf
Barcode (UPC) 760412267575
Net contents 120 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Jan 22, 2022
DSLD ID 259123
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Myo & D-Chiro Inositol by ForestLeaf, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
30
UPC/BARCODE
760412267575
IngredientAmount% DV
Myo-Inositol2000 mg--
Folate400 mcg DFE100%
D-Chiro Inositol50 mg--

Other ingredients: Vegetable Cellulose, Magnesium Stearate, Silicon Dioxide, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

MYO & D-Chiro Inositol helps promote female fertility and reproductive health, by supporting hormone balance and ovarian functions.

Supports regulated PCOS symptoms Promotes a steady hormonal balance Promotes regulated menstrual cycle Promotes healthy egg quality

Vegetarian friendly

Made in the USA

GMP compliant / FDA registered UL certified facility

Non GMO Dairy, gluten, egg, soy & nut free

Tested for absorption

Hormonal & ovarian support

Effective 40:1 ratio

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

+ Folate

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Caronositol is a registered trademark of Biosearch.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, adults take 4 capsules daily, preferably with a meal, or as directed by your healthcare professional. For those with a sensitive stomach, take 2 capsules twice daily.

Precautions

Caution: Keep out of reach of children.

If you are pregnant, nursing, or taking any prescription medicine, consult your physician before taking this product.

Storage

Store in a cool, dry place.

See for yourself

Myo & D-Chiro Inositol by ForestLeaf label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Myo & D-Chiro Inositol by ForestLeaf

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Myo-Inositol

Interacts with
86 drugs
2000 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Myo-Inositol monograph & interactions

Folate

400 mcg DFE per serving Form: Calcium Salt, L-Methylfolate

D-Chiro Inositol

Interacts with
86 drugs
50 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

D-Chiro Inositol monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Magnesium Stearate, Silicon Dioxide, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Myo & D-Chiro Inositol by ForestLeaf Drug Interactions

Want to check YOUR meds against Myo & D-Chiro Inositol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Myo & D-Chiro Inositol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Myo-Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
The maker

Brand information

Manufacturer and brand details for Myo & D-Chiro Inositol, from the product label.

ForestLeaf

See all ForestLeaf products
Name
ForestLeaf
City
Brooklyn
State
NY
ZipCode
11219
Phone Number
929.810.5089
Web Address
www.ForestLeaf.com
Pharmacist Counseling Corner

Myo & D-Chiro Inositol by ForestLeaf: Common Questions

Does Myo & D-Chiro Inositol by ForestLeaf interact with any medications?
Yes. Based on its ingredients, Myo & D-Chiro Inositol has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Myo & D-Chiro Inositol contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my PCOS?
The inositol forms in this product show possibly effective evidence for PCOS. Whether it'll work for you depends on your individual situation, so talk it over with your doctor before starting.
Can I take this if I'm pregnant?
Inositol is rated possibly safe in pregnancy, but only under medical supervision — there isn't enough reliable information yet to say it's fully established. If you're pregnant or planning to be, check with your doctor or pharmacist first.
What are the most common side effects?
The most common are digestive: diarrhea, gas, and nausea. These tend to be mild. One small group of children taking inositol with omega-3 fatty acids also reported cold and allergy symptoms.
Does this product contain any fillers?
The active ingredients are the two inositol forms and folate. The capsule also contains vegetable cellulose, microcrystalline cellulose, magnesium stearate, and silicon dioxide — these are inactive ingredients that help hold the capsule together and make it easier to manufacture.
What's the difference between myo-inositol and D-chiro inositol?
Both are forms of inositol, a compound your body uses in cell signaling. They work similarly — both lower blood glucose and have the same interaction risk with diabetes drugs — but may have slightly different roles in metabolism and PCOS management.
Is folate the same as folic acid?
Folate is the naturally occurring B vitamin; folic acid is its synthetic form. The facts on file don't detail the specific form or dose in this product, so check the label or talk with your pharmacist if you have questions about how much you're getting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Myo & D-Chiro Inositol is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Myo & D-Chiro Inositol label
Go deeper

The Full Monographs Behind Myo & D-Chiro Inositol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Myo & D-Chiro Inositol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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