Noni Ingredients & Drug Interactions
by BareOrganics
What is this page for?
First and foremost: checking Noni against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Noni is a dietary supplement by BareOrganics with 2 active ingredients. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 542 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Noni, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Noni by BareOrganics
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AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Noni by BareOrganics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
BareOrganics Noni Liquid contains 2 active ingredients: potassium and organic noni fruit. Potassium is an essential mineral that supports nerve and muscle function.
Noni, a tropical fruit, has been used traditionally in Pacific and Southeast Asian medicine. The product contains no inactive fillers or other ingredients.
Does it work?
Couldn't assess
The evidence for noni's effectiveness isn't established in the data we hold. The product facts list several uses — asthma, atherosclerosis, athletic performance, burns, cancer, and cardiovascular disease — but each is rated as having insufficient reliable evidence to determine whether noni actually works for these purposes.
Talk with your doctor about whether this product is right for your health goals.
How safe is it?
Well-documented data
Both potassium and noni are generally well tolerated in moderate amounts. Common side effects from potassium include abdominal pain, belching, diarrhea, nausea, and vomiting.
Noni may cause abdominal discomfort and nausea. Rare but serious concerns include high potassium levels, which can cause irregular heartbeat and dangerously low blood pressure, and liver damage (hepatotoxicity) associated with noni in a small number of cases — though it's unclear whether noni itself or contaminants in products caused the injury.
For pregnancy and breastfeeding: potassium from food is fine, but the safety data advises against using potassium supplements during pregnancy without medical guidance. Noni was traditionally used to cause abortion and should not be used during pregnancy.
There isn't enough safety information to know whether noni is appropriate while breastfeeding — talk with your doctor or pharmacist for personalized advice.
Meds to double-check
Moderate interaction found
Before taking BareOrganics Noni Liquid, check with your doctor or pharmacist if you take blood pressure drugs, potassium-sparing diuretics (such as spironolactone), ACE inhibitors, or angiotensin receptor blockers — all carry a moderate risk of dangerously high potassium levels or low blood pressure. Also double-check if you're on warfarin (a blood thinner), phenytoin (a seizure drug), ranitidine, or any medication that can harm the liver.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product combines two potassium-rich ingredients, which makes it risky if you take blood pressure drugs, potassium-sparing diuretics, ACE inhibitors, or ARBs, or if you have kidney disease. Noni also raises concerns about blood pressure drops, liver damage, and interactions with blood thinners and seizure medications.
Talk with your doctor or pharmacist before starting, especially if you're on any prescription medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Noni, straight from the product label.
| Brand | BareOrganics |
|---|---|
| Barcode (UPC) | 818423029658 |
| Net contents | 16 Oz(s); 473 mL |
| Market status | On market |
| Date entered into DSLD | Mar 24, 2020 |
| DSLD ID | 214953 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Noni by BareOrganics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Potassium | 30 mg | 1% |
| organic Noni | 30 Gram(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Organic Noni Juice Noni is one of the most nourishing fruits known to Polynesian herbalists. Its polysaccharides make it beneficial for immunity and overall energy, while antioxidants cleanse the body and protect it from oxidative stress.
Halal
Kosher
Vitamin C Polysaccharides Potassium
Noni contains trace amounts of naturally occurring minerals, enzymes, antioxidant vitamins, phytonutrients and bioflavonoids. It is a natural source of proxeronine and scopoletin.
Formulation
Due to the pure, natural ingredients in this product, taste, color and consistency may vary.
Contains no added sugar, artificial color or preservatives.
Organic
Vegan
Gluten free
Benefits: Overall health & vitality.
Non-GMO
Super fruit juice
Certified Organic by Organic Certifiers, Inc.
General Statements
BPA free
Superfoods to nourish your life.
This container is 100% recyclable. US-ORG-043
Suggested/Recommended/Usage/Directions
Suggested use: Take 2 tablespoons (30 ml) daily or as directed by your health care professional.
Shake well before using.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
USDA Organic
Crescent M Halal OU (Kosher)
FDA Statement of Identity
Dietary Supplement
Precautions
Warning: If you are pregnant or lactating, consult a health care professional before using this product.
Keep out of reach of children.
Do not use this product if the safety seal on the bottle is broken.
Storage
Store in a cool, dry place.
Refrigerate after opening.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Noni by BareOrganics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Noni by BareOrganics
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size30 mL Dosage formLiquid Servings per container16 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Potassium
Interacts with62 drugs
Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...
Potassium monograph & interactionsOrganic Noni
Interacts with542 drugs
Noni is a tropical fruit used widely in folk medicine and sold mostly as a juice or supplement, but solid human evidence for its many claimed benefits...
Organic Noni monograph & interactionsNoni by BareOrganics Drug Interactions
HelloPharmacist Interaction Report
BareOrganics Noni Liquid interacts with medications through its potassium and organic noni content.
The most serious concern is high blood pressure (hypotension) — noni may lower blood pressure further when combined with blood pressure drugs, potentially causing dangerously low pressure.
Read the full breakdown — every affected drug type, severity by severity
Potassium in this product poses a moderate risk of high potassium levels (hyperkalemia) when taken with potassium-sparing water pills (diuretics), ACE inhibitors, or angiotensin receptor blockers (ARBs). These drug classes already reduce how much potassium your body excretes, and adding a potassium-rich supplement increases that risk.
Noni juice itself contains significant potassium — about 6 mEq per 100 mL — so this risk comes from both ingredients.
Noni also interacts moderately with blood thinners like warfarin, which may become less effective; seizure medications like phenytoin, which may drop to ineffective levels; and drugs that can harm the liver. Additionally, noni may increase ranitidine levels, a minor interaction.
Altogether, these interactions span 543 individual medications.
Check your exact medications with the search tool on this page before starting. If you take any blood pressure drug, potassium-sparing diuretic, ACE inhibitor, ARB, warfarin, phenytoin, or any drug that can affect the liver, talk with your doctor or pharmacist first.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Noni?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Noni interact with 542 drugs. Click any drug to see the details.
2 of the 2 ingredients in Noni interact with drugs. Each result below shows which ingredient is responsible. organic Noni Potassium
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Organic Noni + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Organic NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Organic Noni + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Noni with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Noni
Ace Inhibitors (Aceis)
Theoretically, combining noni and ACE inhibitors might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ACE inhibitors, which can also increase potassium levels.
Angiotensin Receptor Blockers (Arbs)
Theoretically, combining noni and ARBs might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ARBs, which can also increase potassium levels.
Antihypertensive Drugs
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Preliminary clinical research suggests that drinking noni juice can reduce blood pressure in individuals with hypertension.
Hepatotoxic Drugs
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
There is concern that noni might cause hepatotoxicity in some patients. Advise patients against combining noni with potentially hepatotoxic drugs.
Phenytoin (Dilantin)
Theoretically, taking noni fruit juice concomitantly with phenytoin may lower phenytoin levels and increase the risk of seizures.
In one case report, an adult taking phenytoin for partial seizures experienced low serum phenytoin levels while taking noni juice 90-200 mL daily. Serum phenytoin levels increased after decreasing noni juice consumption; similarly, serum phenytoin levels decreased after increasing noni juice consumption. Some researchers believe noni juice may induce cytochrome P450 2C9 enzymes, which would decrease phenytoin levels, but this has not been well studied. Patients may need additional monitoring when starting or stopping noni juice supplementation.
Potassium-Sparing Diuretics
Theoretically, combing noni and a potassium-sparing diuretic might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with potassium-sparing diuretics, which can also increase potassium levels.
Warfarin (Coumadin)
Theoretically, taking noni juice concomitantly with warfarin might decrease the effectiveness of warfarin.
In one case, a 41-year-old patient stabilized on warfarin had a decreased international normalized ratio (INR) following consumption of a specific commercial noni juice product (Noni juice 4 Everything). While the patient was still taking noni juice, an increase in warfarin dose did not produce an increase in INR. However, it should be noted that this particular product contained extracts and derivatives from more than 115 components, many of which contained vitamin K. Furthermore, vitamin K was listed as a separate ingredient of the product, suggesting that the product was possibly fortified with vitamin K. It has not been verified that noni fruit alone contains a significant amount of vitamin K or interacts with warfarin.
Ranitidine (Zantac)
Taking noni fruit with ranitidine might increase the levels and clinical effects of ranitidine.
Clinical evidence shows that taking an aqueous extract of noni fruit 30 minutes prior to taking a single oral dose of ranitidine can increase the rate of absorption and plasma concentration of ranitidine.
Potassium
Ace Inhibitors (Aceis)
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Angiotensin Receptor Blockers (Arbs)
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Potassium-Sparing Diuretics
Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.
Brand information
Manufacturer and brand details for Noni, from the product label.
BareOrganics
See all BareOrganics products- Name
- BareOrganics
- Street Address
- 7702 East Doubletree Ranch Rd., Suite 300, #305
- City
- Scottsdale
- State
- AZ
- ZipCode
- 85258
- Phone Number
- 1-800-848-7910
- Web Address
- www.bareorganics.com
Noni by BareOrganics: Common Questions
Does Noni by BareOrganics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is noni safe to take while pregnant?
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Can I take this if I have kidney disease?
Is noni proven to work for asthma, cancer, or heart disease?
Why does this product interact with so many medications?
Can this product cause liver damage?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Noni is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Noni’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Potassium
Interacts with 62 drugsPotassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...
Read the full Potassium monograph → Herb & supplement monographNoni
Interacts with 542 drugsNoni is a tropical fruit used widely in folk medicine and sold mostly as a juice or supplement, but solid human evidence for its many claimed benefits is limited. While moderate juice intake...
Read the full Noni monograph →Sources & How We Checked
Noni's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Potassium 12 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
- Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
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