Interactions on record — worth a quick check against your medications. Based on 6 of 10 ingredients. Check your meds →
Dietary supplement

Probiotic-10 100 Billion Ingredients & Drug Interactions

by NOW

Probiotic-10 100 Billion label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Probiotic-10 100 Billion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Probiotic-10 100 Billion is a dietary supplement by NOW with 10 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacilli acidophilus La-14, Bifidobacterium breve Bb-03, Bifidobacterium longum Bl-05. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Probiotic-10 100 Billion by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic-10 100 Billion by NOW — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Probiotic-10 100 Billion by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “Blend of 10 strains of Probiotic Bacteria” is a proprietary blend — the label gives one combined amount (520 mg) without saying how much of each component you get.

This product contains ten active probiotic bacterial strains: Lactobacillus acidophilus La-14, Bifidobacterium breve Bb-03, Lactobacillus rhamnosus LR-32, Bifidobacterium longum Bl-05, Bifidobacterium lactis BI-04, Streptococcus thermophilus ST-21, Lactobacillus plantarum Lp-115, Lacticaseibacillus casei Lc-11, Lacticaseibacillus paracasei Lpc-37, and Lactobacillus salivarius Ls-33. Each strain is a live organism meant to support your gut flora.

The inactive ingredients are hypromellose, microcrystalline cellulose, fructooligosaccharides, ascorbyl palmitate, and silicon dioxide.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: healthy digestion and gut microbiome balance.
  • We looked for evidence on: Antibiotic-associated diarrhea, Diarrhea, Constipation, Colic, Helicobacter pylori, Clostridioides difficile infection — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Helicobacter pylori, Irritable bowel syndrome (IBS).
  • Also on file: Lacticaseibacillus Paracasei is rated "Possibly Ineffective" for Constipation.

The evidence for these strains is mixed and often limited. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

Lacticaseibacillus paracasei is possibly effective for atopic dermatitis (eczema) and allergic rhinitis (hay fever). Most other conditions in the trials—including anxiety, asthma, constipation, depression, diabetes, and liver disease—either showed insufficient reliable evidence or possibly ineffective results.

The data we hold doesn't establish clear benefit for most uses, so talk with your doctor about whether this blend makes sense for your particular reason.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Bifidobacterium Breve Bifidobacterium Longum Streptococcus Thermophilus Lacticaseibacillus Casei Lacticaseibacillus Paracasei

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These probiotics are generally well tolerated in healthy adults and children. The main safety concern is that live bacterial preparations can theoretically cause infection in people with weakened immune systems, serious illness, or indwelling catheters—rare cases of bacteremia (bacteria in the bloodstream), sepsis, and other infections have been reported, mostly in critically ill or very young patients.

Orally, mild and uncommon gastrointestinal side effects like abdominal discomfort, bloating, flatulence, and diarrhea may occur. Pregnancy is rated Possibly Safe for most ingredients we checked; Lactobacillus acidophilus notes data are limited, and Bifidobacterium longum and Lacticaseibacillus paracasei are rated Possibly Safe for both pregnancy and lactation.

For the three strains we couldn't check, safety data isn't on file.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Bifidobacterium Breve Bifidobacterium Longum Streptococcus Thermophilus Lacticaseibacillus Casei Lacticaseibacillus Paracasei

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bifidobacterium Breve, Bifidobacterium Longum, Lacticaseibacillus Paracasei, Lacticaseibacillus Casei.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you're on antibiotic drugs. Since five of the ten strains interact with antibiotics (Moderate severity), separating the timing of your doses is important to keep the probiotics working.

No other medication types show documented interactions with the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This ten-strain blend may be worth considering if you're interested in supporting gut health, especially if you have irritable bowel syndrome, antibiotic-associated diarrhea, or certain allergic conditions—though the evidence is modest. Be cautious if you're seriously ill, immunocompromised, or have indwelling catheters, and separate doses from antibiotics by a few hours.

Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or have ongoing health concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Probiotic-10 100 Billion, straight from the product label.

Brand NOW
Barcode (UPC) 733739029041
Net contents 60 Veg Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 335293
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Probiotic-10 100 Billion by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Capsule(s)
Maximum serving Sizes:
1 Veg Capsule(s)
Servings per container
60
UPC/BARCODE
733739029041
IngredientAmount% DV
Lactobacilli acidophilus La-140 NP--
Bifidobacterium breve Bb-030 NP--
Lactobacillus rhamnosus LR-320 NP--
Bifidobacterium longum Bl-050 NP--
Bifidobacterium lactis BI-040 NP--
Blend of 10 strains of Probiotic Bacteria520 mg--
Streptococcus thermophilus ST-210 NP--
Lactobacillus plantarum Lp-1150 NP--
Lacticaseibacillus casei Lc-110 NP--
Lacticaseibacillus paracasei Lpc-370 NP--
Lactobacilli salivarius Ls-330 NP--

Other ingredients: Hypromellose, Microcrystalline Cellulose, Fructooligosaccharides, Ascorbyl Palmitate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1 capsule daily between meals or on an empty stomach.

Storage

Keep refrigerated to maintain potency.

Formula

NOW Probiotic-10 offers a balanced spectrum of live organisms consisting of acid-resistant probiotic bacteria strains that are known to naturally colonize the human GI tract. Probiotic bacteria are critical for healthy digestion, help maintain the integrity of the intestinal lining, support proper intestinal motility and participate in the detoxification process. This potent Probiotic-10 formula delivers 100 billion live organisms to help restore healthy flora following occassional but temporary disruptions to intestinal balance.

10 probiotic strains

Triangle K (Kosher)

This product is formulated to deliver a potency of 100 billion CFU through the best by date.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: Consult physician if pregnant/nursing, taking medication (especially immune-suppressing drugs), or have a medical condition (especially if immune system is compromised).

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Seals/Symbols

GMP Quality Assured

Triangle K (Kosher)

Strain Verified

Formulation

Restorative care For temporary disruptions to intestinal balance

Dairy, soy & gluten free Non-GMO

Vegetarian/Vegan

Made and quality tested in the USA with globally sourced ingredients.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts or sesame ingredients containing these allergens.

The probiotic strains in this product have been identity-verified using DNA-fingerprinting technology.

FDA Statement of Identity

A Dietary Supplement

General Statements

Digestive Family owned since 1968.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Probiotic-10 100 Billion by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Probiotic-10 100 Billion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Probiotic-10 100 Billion by NOW

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Blend of 10 strains of Probiotic Bacteria

520 mg per serving

Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Fructooligosaccharides, Ascorbyl Palmitate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Probiotic-10 100 Billion by NOW Drug Interactions

Want to check YOUR meds against Probiotic-10 100 Billion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacilli acidophilus La-14 182
Bifidobacterium breve Bb-03 182
Bifidobacterium longum Bl-05 182
Lacticaseibacillus casei Lc-11 182
Lacticaseibacillus paracasei Lpc-37 182

Individual Drug Interactions

The ingredients in Probiotic-10 100 Billion interact with 182 drugs. Click any drug to see the details.

5 of the 10 ingredients in Probiotic-10 100 Billion interact with drugs. Each result below shows which ingredient is responsible. Lactobacilli acidophilus La-14 Bifidobacterium breve Bb-03 Bifidobacterium longum Bl-05 Lacticaseibacillus casei Lc-11 Lacticaseibacillus paracasei Lpc-37

Each ingredient & the kinds of drugs it affects

For each ingredient in Probiotic-10 100 Billion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacilli acidophilus La-141 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacilli acidophilus La-14 full monograph & interactions

Bifidobacterium breve Bb-031 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium breve Bb-03 full monograph & interactions

Bifidobacterium longum Bl-051 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium longum Bl-05 full monograph & interactions

Lacticaseibacillus casei Lc-111 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lacticaseibacillus casei with antibiotic drugs might decrease the effectiveness of L. casei.
L. casei preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. casei preparations by at least two hours.

Likelihood Probable Evidence D
Lacticaseibacillus casei Lc-11 full monograph & interactions

Lacticaseibacillus paracasei Lpc-371 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lacticaseibacillus paracasei with antibiotic drugs might decrease the effectiveness of L. paracasei.
L. paracasei preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. paracasei preparations by at least two hours.

Likelihood Probable Evidence D
Lacticaseibacillus paracasei Lpc-37 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Probiotic-10 100 Billion, from the product label.

NOW

See all NOW products
Name
NOW FOODS
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Probiotic-10 100 Billion by NOW: Common Questions

Does Probiotic-10 100 Billion by NOW interact with any medications?
Yes. Based on its ingredients, Probiotic-10 100 Billion has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Probiotic-10 100 Billion contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Should I take this at the same time as my antibiotic?
No—space them apart. Antibiotics kill the live bacteria in this probiotic, so taking them together makes the probiotic less effective. Ask your pharmacist how far apart to take them; often a few hours is enough.
What is Lactobacillus acidophilus and what's it supposed to do?
It's a live beneficial bacterium found naturally in your gut. In this product it may help with irritable bowel syndrome, antibiotic-associated diarrhea, and bacterial vaginosis, though the evidence is still developing. Most people tolerate it well.
Can I take this while pregnant?
Most of the strains are rated Possibly Safe in pregnancy, but safety data are limited for some. Talk to your doctor before starting—they can weigh the benefit for your situation against what we know.
What are common side effects?
Most people have no problems. In trials, some people reported mild gas, bloating, or stomach discomfort, but these are uncommon and usually temporary.
Is this safe if I have a weakened immune system?
You should check with your doctor first. Probiotics containing live organisms can pose a small risk in people who are seriously ill or immunocompromised, so personalized advice is important.
Does this product have any fillers or additives?
The active ingredients are the ten bacterial strains. The inactive ingredients are hypromellose, microcrystalline cellulose, fructooligosaccharides, ascorbyl palmitate, and silicon dioxide—all typical capsule and stabilizing materials.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Probiotic-10 100 Billion is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Probiotic-10 100 Billion label
Go deeper

The Full Monographs Behind Probiotic-10 100 Billion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Breve

Interacts with 182 drugs

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...

Read the full Bifidobacterium Breve monograph → Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Streptococcus Thermophilus

Streptococcus thermophilus is a friendly bacterium used as a probiotic, often combined with other strains in yogurt and supplements. It is generally well tolerated in healthy people and may...

Read the full Streptococcus Thermophilus monograph → Herb & supplement monograph

Lacticaseibacillus Casei

Interacts with 182 drugs

Lacticaseibacillus casei (formerly Lactobacillus casei) is a 'friendly' probiotic bacterium found in fermented foods and many supplements. It is most studied for digestive issues like diarrh...

Read the full Lacticaseibacillus Casei monograph → Herb & supplement monograph

Lacticaseibacillus Paracasei

Interacts with 182 drugs

Lacticaseibacillus paracasei (formerly Lactobacillus paracasei) is a probiotic bacterium found in fermented foods and supplements that is widely used to support gut and immune health. Some s...

Read the full Lacticaseibacillus Paracasei monograph →
Sources

Sources & How We Checked

Probiotic-10 100 Billion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 92 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Breve 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  4. Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
  5. Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
  6. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  7. Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
  8. Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
  9. Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed

See these in context on the Bifidobacterium Breve monograph →

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
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Lacticaseibacillus Casei 10 references
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Lacticaseibacillus Paracasei 16 references
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See these in context on the Lacticaseibacillus Paracasei monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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