Radiant Care 11:1 Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Radiant Care 11:1 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Radiant Care 11:1 is a dietary supplement by Get Healthy Again with 6 active ingredients. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 1,678 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Green Tea extract, Coenzyme Q10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Radiant Care 11:1 by Get Healthy Again
Ask about any prescription or over-the-counter medication and we check it for interactions with Radiant Care 11:1 by Get Healthy Again — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Radiant Care 11:1 by Get Healthy Again
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Radiant Care 11:1 is a 19-ingredient liquid supplement. Its active ingredients include potassium (from potassium sorbate), sunflower lecithin, black currant seed oil, black cumin seed oil, grape seed oil, coenzyme Q10, lime essential oil, xylitol, green tea extract, sesame seed oil, grapefruit essential oil, frankincense (Boswellia serrata), rosemary, and clove.
It also contains citric acid as a preservative and flavor agent, plus inactive ingredients—fillers, binders, and other formulation components—listed as naturally occurring substances.
Does it work?
Strong evidence
Evidence for this product's active ingredients is mixed. Green tea extract is rated Likely Effective for human papillomavirus (HPV) prevention and Possibly Effective for ovarian cancer and high cholesterol.
Xylitol is Likely Effective for preventing dental cavities. Coenzyme Q10 is Likely Effective for CoQ10 deficiency itself and Possibly Effective for fibromyalgia, migraines, congestive heart failure, and diabetic nerve pain.
Black cumin seed oil, black currant seed oil, and frankincense are Possibly Effective for specific conditions—black cumin for acne, allergies, asthma, and diabetes; black currant for various uses; and frankincense for osteoarthritis. Grape seed oil is Possibly Effective for chronic venous insufficiency and Possibly Ineffective for allergies and obesity.
Sesame seed oil is Possibly Effective for high blood pressure. For many of the other active ingredients—rosemary, clove, lime, citric acid, and lecithin—the evidence is insufficient to establish effectiveness, or they are rated Likely Ineffective (as lecithin is for Alzheimer disease).
How safe is it?
Well-documented data
Most ingredients in this product are generally well tolerated at typical supplement doses. Potassium sorbate is well tolerated orally, though high doses can cause abdominal pain, diarrhea, nausea, and vomiting; serious risk of dangerously high blood potassium exists in people with kidney disease.
Lecithin, citric acid, coenzyme Q10, xylitol, and grapefruit are generally well tolerated, though citric acid at high topical concentrations can cause severe skin irritation and burns. Green tea extract is well tolerated in moderate amounts but rarely causes liver injury at high doses.
Black cumin seed oil's safety data advises against use in pregnancy and is not rated for breastfeeding; avoid medicinal doses. Black currant, grape seed, sesame, frankincense, rosemary, and clove all carry cautions: food amounts are generally safe, but concentrated supplements lack long-term safety data.
Frankincense is rated Likely Safe in pregnancy. Rosemary is rated Possibly Unsafe in pregnancy and should be avoided in medicinal doses.
Grapefruit safety data is not rated for pregnancy or breastfeeding, and large quantities may increase breast cancer risk in postmenopausal women.
Meds to double-check
Major interaction found
Before taking this product, double-check with your doctor or pharmacist if you take any of these medication types: blood thinners or antiplatelet drugs (warfarin, clopidogrel, aspirin—Major risk from grapefruit and green tea, Moderate from black cumin, grape seed, frankincense, rosemary, and clove), heart rhythm or blood pressure medications (nadolol, atorvastatin, ACE inhibitors, ARBs, antihypertensives—Major risk from green tea and grapefruit, Moderate from potassium sorbate, black cumin, grape seed, sesame, and coenzyme Q10), seizure medications (phenytoin, valproate, ethosuximide, felbamate—Moderate risk from green tea), immunosuppressants (cyclosporine—Major from grapefruit, Moderate from black cumin and frankincense), or diabetes medications (Moderate risk from black cumin, sesame, rosemary, and clove). Liver enzyme interactions are also documented with multiple ingredients affecting how your body processes other drugs.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
This is a multi-ingredient supplement with active compounds for potential benefits in heart health, brain function, immunity, and inflammation—but it carries significant drug interactions, especially with heart and blood pressure medications, blood thinners, seizure drugs, and cholesterol drugs. If you take any prescription medication, especially beta-blockers, ACE inhibitors, ARBs, anticoagulants, or seizure medications, review your exact drugs with your pharmacist or doctor before starting this product.
Most ingredients are well tolerated in food amounts, but concentrated supplements pose more risk; pregnant or breastfeeding women should clear it with their healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 15 of 19 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Radiant Care 11:1, straight from the product label.
| Brand | Get Healthy Again |
|---|---|
| Barcode (UPC) | 640841969472 |
| Net contents | 4 fl. Oz.; 120 mL |
| Market status | On market |
| Date entered into DSLD | Apr 25, 2018 |
| DSLD ID | 175624 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Radiant Care 11:1 by Get Healthy Again, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 25 Calorie(s) | -- |
| Calories from Fat | 20 Calorie(s) | -- |
| Saturated Fat | 0.2 Gram(s) | -- |
| Trans Fat | 0 Gram(s) | -- |
| Cholesterol | 0 Gram(s) | -- |
| Total Fat | 2.4 Gram(s) | 9% |
| Polyunsaturated Fat | 1.8 Gram(s) | -- |
| Monounsaturated Fat | 0.4 Gram(s) | -- |
| Potassium Sorbate | 0 NP | -- |
| Sunflower Lecithin | 0 NP | -- |
| Citric Acid | 0 NP | -- |
| Black Currant seed Oil | 0 NP | -- |
| Black Cumin seed oil | 0 NP | -- |
| Grape seed Oil | 0 NP | -- |
| Proprietary Nutrient Blend | 4000 mg | -- |
| Coenzyme Q10 | 50 mg | -- |
| Organic, Cold Pressed, Full Spectrum, Non-GMO | 0 NP | -- |
| Organic Essential Oils | 0 NP | -- |
| Lime Essential Oil | 0 NP | -- |
| Blending Agents | 0 NP | -- |
| Xylitol | 0 NP | -- |
| Solubilized Micronutrients | 0 NP | -- |
| QualiC | 75 mg | 100% |
| Green Tea extract | 30 mg | -- |
| Sesame seed Oil | 0 NP | -- |
| White Grapefruit Essential Oil | 0 NP | -- |
| Frankincense | 0 NP | -- |
| Rosemary | 0 NP | -- |
| Clove | 0 NP | -- |
| Purified Structured Mineral Water | 0 NP | -- |
Other ingredients: This blend also includes naturally occurring
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Not a significant source of sugar, sodium, proteins, vit. A, calcium, & iron.
Other ingredients: Please see listed on right hand side of this label.
Naturally high in antioxidants and other essential nutrients.
GHA Naturals
Helping organs radiate with life internally
Proprietary, patent pending, low temperature, transduction and emulsification process that micronizes, microblends, and activates parent essential oil and nutraceutical/nutrient content for increased bioavailability.
Transdermal
Precautions
Keep out of reach of children.
People on medications, pregnant or nursing women should consult their doctor before using this or any other supplement.
Storage
Store in a cool, dry place. Keep tightly sealed.
Suggested/Recommended/Usage/Directions
Use within 60 days of opening.
Use topically for radiant skin
Shake before use
Suggested Use: Adults take 1 teaspoon (24 pumps) daily. Can be either taken internally or on an empty stomach or applied (massaged-in) through the skin. Double these amounts for re-balancing period, usually this is the first 60 to 90 days of use. Take extra whenever a mental or physical energy boost is required.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Manufactured with care in the US.
Formulation
No soy, wheat, gluten, dairy, fish, shellfish, or tree-nuts. No additives or fillers. No GMO ingredients.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Radiant Care 11:1 by Get Healthy Again label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Radiant Care 11:1 by Get Healthy Again
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 tsp Dosage formLiquid Servings per container25 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Nutrient Blend
- › Organic, Cold Pressed, Full Spectrum, Non-GMO
- › Organic Essential Oils
- › Blending Agents
Solubilized Micronutrients
- › Coenzyme Q10
- › QualiC
- › Green Tea extract
Other (inactive) ingredients: This blend also includes naturally occurring. These complete the product’s ingredient list but are not active constituents.
Radiant Care 11:1 by Get Healthy Again Drug Interactions
HelloPharmacist Interaction Report
Radiant Care 11:1 by Get Healthy Again contains several ingredients with documented drug interactions.
Through its potassium sorbate, black cumin seed oil, grape seed oil, coenzyme Q10, green tea extract, grapefruit essential oil, and frankincense, this product interacts with a range of medications. The most serious interaction is between the green tea extract and nadolol (a beta-blocker for heart rhythm and blood pressure)—green tea can reduce nadolol levels by up to 85%, potentially weakening its therapeutic effect.
Read the full breakdown — every affected drug type, severity by severity
The grapefruit essential oil carries Major-severity interactions with eight medications, including cyclosporine (an immunosuppressant), amiodarone (an antiarrhythmic), buspirone (an anxiety drug), and dextromethorphan (a cough suppressant). Grapefruit can significantly raise blood levels of these drugs, increasing the risk of side effects.
Green tea extract also has Major interactions with atorvastatin (a cholesterol drug) and ephedrine, and Moderate interactions with several seizure medications that it may reduce in effectiveness.
Potassium sorbate presents Moderate-severity interactions with blood pressure medications (ACE inhibitors and ARBs) and potassium-sparing diuretics—all can raise potassium to dangerous levels. Black cumin seed oil, grape seed oil, sesame seed oil, and frankincense each carry multiple Moderate interactions affecting blood thinners (anticoagulants and antiplatelets), blood pressure drugs, diabetes medications, and various drugs metabolized by liver enzymes.
Altogether, these interactions span 1,679 individual medications.
We could not check polyunsaturated fat, monounsaturated fat, the proprietary nutrient blend, the organic essential oils blend, the blending agents, the solubilized micronutrients blend, QualiC, or purified structured mineral water—our data does not include them. Before starting this product, check with your doctor or pharmacist about any prescription or over-the-counter medications you take.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Radiant Care 11:1?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Radiant Care 11:1 interact with 1,678 drugs. Click any drug to see the details.
2 of the 6 ingredients in Radiant Care 11:1 interact with drugs. Each result below shows which ingredient is responsible. Green Tea extract Coenzyme Q10
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Radiant Care 11:1 — through 6 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Ado-trastuzumab Emtansine interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Ado-trastuzumab Emtansine interactionGrape Seed OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Oil + Ado-trastuzumab Emtansine interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Ado-trastuzumab Emtansine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Ado-trastuzumab Emtansine interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Radiant Care 11:1 — through 6 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Abemaciclib interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Abemaciclib interactionGrape Seed OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Oil + Abemaciclib interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Abemaciclib interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Abemaciclib interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Radiant Care 11:1 — through 6 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Abiraterone interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Abiraterone interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Abiraterone interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Abiraterone interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Abiraterone interactionGrape Seed OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Oil + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Radiant Care 11:1 — through 6 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Abiraterone Acetate interactionGrape Seed OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Oil + Abiraterone Acetate interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Abiraterone Acetate interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Abiraterone Acetate interactionGreen Tea ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Abiraterone Acetate interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Abiraterone Acetate interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Radiant Care 11:1 — through 7 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Acalabrutinib interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acalabrutinib interactionGrape Seed OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Oil + Acalabrutinib interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Acalabrutinib interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Acalabrutinib interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Acalabrutinib interactionSesame Seed OilP-glycoprotein Substrates Minor
Interaction Summary
Theoretically, sesame might alter the transport of P-glycoprotein substrates.
Read the full Sesame Seed Oil + Acalabrutinib interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Radiant Care 11:1 — through 9 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP1A2.
Read the full White Grapefruit Essential Oil + Acetaminophen, Aspirin, Caffeine interactionBlack Cumin Seed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, black seed may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Black Cumin Seed Oil + Acetaminophen, Aspirin, Caffeine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Aspirin, Caffeine interactionGrape Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +2 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Oil + Acetaminophen, Aspirin, Caffeine interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Aspirin, Caffeine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Aspirin, Caffeine interactionGreen Tea ExtractAnticoagulant/antiplatelet Drugs, Stimulant Drugs +2 Moderate
Interaction Summary
Theoretically, green tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Green Tea Extract + Acetaminophen, Aspirin, Caffeine interactionBlack Currant Seed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Read the full Black Currant Seed Oil + Acetaminophen, Aspirin, Caffeine interactionCloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Clove + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Radiant Care 11:1 — through 7 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCaffeine, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Major
Interaction Summary
Grapefruit juice can decrease the clearance of caffeine, potentially increasing the effects and adverse effects of caffeine.
Read the full White Grapefruit Essential Oil + Acetaminophen, Butalbital, Caffeine interactionCloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Clove + Acetaminophen, Butalbital, Caffeine interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Butalbital, Caffeine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Butalbital, Caffeine interactionGreen Tea ExtractStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Acetaminophen, Butalbital, Caffeine interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Butalbital, Caffeine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Acetaminophen, Butalbital, Caffeine, Codeine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Butalbital, Caffeine, Codeine interactionBlack Cumin Seed OilCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Black Cumin Seed Oil + Acetaminophen, Butalbital, Caffeine, Codeine interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Acetaminophen, Butalbital, Caffeine, Codeine interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Acetaminophen, Butalbital, Caffeine, Codeine interactionGreen Tea ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionGrape Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Oil + Acetaminophen, Butalbital, Caffeine, Codeine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCaffeine, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Major
Interaction Summary
Grapefruit juice can decrease the clearance of caffeine, potentially increasing the effects and adverse effects of caffeine.
Read the full White Grapefruit Essential Oil + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionBlack Cumin Seed OilCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Black Cumin Seed Oil + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionGrape Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +2 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Oil + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionCloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Clove + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCaffeine, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Grapefruit juice can decrease the clearance of caffeine, potentially increasing the effects and adverse effects of caffeine.
Read the full White Grapefruit Essential Oil + Acetaminophen, Caffeine, Codeine interactionCloveCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Clove + Acetaminophen, Caffeine, Codeine interactionGreen Tea ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Acetaminophen, Caffeine, Codeine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Caffeine, Codeine interactionBlack Cumin Seed OilCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Black Cumin Seed Oil + Acetaminophen, Caffeine, Codeine interactionGrape Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Oil + Acetaminophen, Caffeine, Codeine interactionFrankincenseCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Frankincense + Acetaminophen, Caffeine, Codeine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCaffeine, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Major
Interaction Summary
Grapefruit juice can decrease the clearance of caffeine, potentially increasing the effects and adverse effects of caffeine.
Read the full White Grapefruit Essential Oil + Acetaminophen, Caffeine, Codeine, Salicylamide interactionFrankincenseCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Frankincense + Acetaminophen, Caffeine, Codeine, Salicylamide interactionBlack Cumin Seed OilCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Black Cumin Seed Oil + Acetaminophen, Caffeine, Codeine, Salicylamide interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Caffeine, Codeine, Salicylamide interactionCloveCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Clove + Acetaminophen, Caffeine, Codeine, Salicylamide interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Caffeine, Codeine, Salicylamide interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCaffeine, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Grapefruit juice can decrease the clearance of caffeine, potentially increasing the effects and adverse effects of caffeine.
Read the full White Grapefruit Essential Oil + Acetaminophen, Caffeine, Dihydrocodeine interactionGreen Tea ExtractStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Acetaminophen, Caffeine, Dihydrocodeine interactionFrankincenseCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Frankincense + Acetaminophen, Caffeine, Dihydrocodeine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Caffeine, Dihydrocodeine interactionBlack Cumin Seed OilCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Black Cumin Seed Oil + Acetaminophen, Caffeine, Dihydrocodeine interactionGrape Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Oil + Acetaminophen, Caffeine, Dihydrocodeine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Radiant Care 11:1 — through 7 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP1A2.
Read the full White Grapefruit Essential Oil + Acetaminophen, Caffeine, Isometheptene interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Caffeine, Isometheptene interactionGreen Tea ExtractStimulant Drugs, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Acetaminophen, Caffeine, Isometheptene interactionCloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Clove + Acetaminophen, Caffeine, Isometheptene interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Caffeine, Isometheptene interactionGrape Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Oil + Acetaminophen, Caffeine, Isometheptene interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Acetaminophen, Caffeine, Pyrilamine interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Caffeine, Pyrilamine interactionGreen Tea ExtractDiuretic Drugs, Stimulant Drugs +2 Moderate
Interaction Summary
Theoretically, using green tea with diuretic drugs might increase the risk of hypokalemia.
Read the full Green Tea Extract + Acetaminophen, Caffeine, Pyrilamine interactionBlack Cumin Seed OilDiuretic Drugs Moderate
Interaction Summary
Theoretically, taking black seed with diuretic drugs might increase potassium loss and the risk of hypokalemia.
Read the full Black Cumin Seed Oil + Acetaminophen, Caffeine, Pyrilamine interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Acetaminophen, Caffeine, Pyrilamine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Caffeine, Pyrilamine interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Acetaminophen, Caffeine, Pyrilamine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilDextromethorphan (robitussin Dm, Others), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Major
Interaction Summary
Grapefruit juice can increase blood levels of dextromethorphan, potentially increasing the effects and adverse effects of dextromethorphan.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionGreen Tea ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionGrape Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +2 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionCloveCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Clove + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionFrankincenseCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionLime Essential OilPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionBlack Cumin Seed OilCns Depressants, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionCloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Clove + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilDextromethorphan (robitussin Dm, Others), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Major
Interaction Summary
Grapefruit juice can increase blood levels of dextromethorphan, potentially increasing the effects and adverse effects of dextromethorphan.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionCloveCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Clove + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionLime Essential OilPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionFrankincenseCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilDextromethorphan (robitussin Dm, Others), Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Grapefruit juice can increase blood levels of dextromethorphan, potentially increasing the effects and adverse effects of dextromethorphan.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionGreen Tea ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionGrape Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +2 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP1A2.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionCloveCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Clove + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionGrape Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionGreen Tea ExtractStimulant Drugs, Phenylpropanolamine +2 Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilDextromethorphan (robitussin Dm, Others), Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Grapefruit juice can increase blood levels of dextromethorphan, potentially increasing the effects and adverse effects of dextromethorphan.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP1A2.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionLime Essential OilPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionGreen Tea ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionCloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Clove + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Phenylephrine interactionGreen Tea ExtractStimulant Drugs, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionGrape Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Phenylephrine interactionLime Essential OilPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Phenylephrine interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Acetaminophen, Chlorpheniramine, Phenylephrine interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Phenylephrine interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Phenylephrine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP1A2.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionGrape Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionGreen Tea ExtractStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionCloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Clove + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionGreen Tea ExtractPhenylpropanolamine, Stimulant Drugs +2 Moderate
Interaction Summary
Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP1A2.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionBlack Cumin Seed OilSerotonergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionCloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Clove + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionGreen Tea ExtractStimulant Drugs, Phenylpropanolamine +2 Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionGrape Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionCloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Clove + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionGreen Tea ExtractPhenylpropanolamine, Stimulant Drugs +2 Moderate
Interaction Summary
Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP1A2.
Read the full White Grapefruit Essential Oil + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionGreen Tea ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionFrankincenseCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Frankincense + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionGrape Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Oil + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP1A2.
Read the full White Grapefruit Essential Oil + Acetaminophen, Dextromethorphan interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Dextromethorphan interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Dextromethorphan interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Dextromethorphan interactionCloveCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Clove + Acetaminophen, Dextromethorphan interactionGreen Tea ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Acetaminophen, Dextromethorphan interactionFrankincenseCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Frankincense + Acetaminophen, Dextromethorphan interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Major
Interaction Summary
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full White Grapefruit Essential Oil + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionGrape Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Oil + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionGreen Tea ExtractStimulant Drugs, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionFrankincenseCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Frankincense + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionCloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Clove + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Radiant Care 11:1 — through 8 ingredients. Tap an ingredient for the detail:
White Grapefruit Essential OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP1A2.
Read the full White Grapefruit Essential Oil + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionCloveCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Clove + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionGreen Tea ExtractStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionBlack Cumin Seed OilSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining serotonergic drugs with black seed might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Read the full Black Cumin Seed Oil + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionLime Essential OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime Essential Oil + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionGrape Seed OilCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Grape Seed Oil + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionFrankincenseCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Frankincense + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Radiant Care 11:1 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Green Tea extract
Atorvastatin (Lipitor)
Green tea extract seems to reduce the levels and clinical effects of atorvastatin.
In healthy humans, taking green tea extract 300 mg or 600 mg along with atorvastatin reduces plasma levels of atorvastatin by approximately 24%. The elimination of atorvastatin is not affected. Atorvastatin is a substrate of organic anion-transporting polypeptides (OATPs). Research shows that two of the major catechins found in green tea, epicatechin gallate (ECG) and epigallocatechin gallate (EGCG), inhibit OATPs. Some OATPs are expressed in the small intestine and are responsible for the uptake of drugs and other compounds, which may have resulted in reduced plasma levels of atorvastatin. It is not clear if drinking green tea alters the absorption of atorvastatin.
Ephedrine
Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Green tea contains caffeine. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.
Nadolol (Corgard)
Green tea seems to reduce the levels and clinical effects of nadolol.
Preliminary clinical research shows that green tea consumption reduces plasma concentrations of nadolol. Compared to a control group, both peak levels and total drug exposure (AUC) of nadolol were reduced by approximately 85% in subjects who drank green tea daily for two weeks. Drinking green tea with nadolol also significantly reduced nadolol's systolic blood pressure lowering effect. Other clinical research shows that a single dose of green tea can affect plasma nadolol levels for at least one hour. Green tea catechins have been shown to inhibit organic anion transporting polypeptides (OATP), one of which, OATP1A2, is involved in the uptake of nadolol in the intestine The interaction is thought to be due primarily to the epigallocatechin gallate (EGCG) content of green tea.
5-Fluorouracil
Theoretically, high doses of green tea might increase the effects and side effects of 5-fluorouracil.
Animal research shows that taking green tea in amounts equivalent to about 6 cups daily in humans for 4 weeks prior to receiving a single injection of 5-fluorouracil increases the maximum plasma levels of 5-fluorouracil by about 2.5-fold and the area under the curve by 425%.
Adenosine (Adenocard)
Theoretically, green tea might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Green tea contains caffeine. Caffeine is a competitive inhibitor of adenosine at the cellular level. However, caffeine doesn't seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.
Anticoagulant/Antiplatelet Drugs
Theoretically, green tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Conflicting reports exist regarding the effect of green tea on bleeding risk when used with anticoagulant or antiplatelet drugs; however, most evidence suggests that drinking green tea in moderate amounts is unlikely to cause a significant interaction. Green tea contains small amounts of vitamin K, approximately 7 mcg per cup. Some case reports have associated the antagonism of warfarin with the vitamin K content of green tea. However, these reports are rare, and very large doses of green tea (about 8-16 cups daily) appear to be needed to cause these effects. Furthermore, the catechins and caffeine in green tea are reported to have antiplatelet activity.
Beta-Adrenergic Agonists
Green tea contains caffeine. Theoretically, concomitant use of large amounts of caffeine might increase cardiac inotropic effects of beta-agonists.
Bortezomib (Velcade)
Theoretically, green tea might interfere with the effects of bortezomib.
In vitro research shows that green tea polyphenols, such as epigallocatechin gallate (EGCG), interact with bortezomib and block its proteasome inhibitory action. This prevents the induction of cell death in multiple myeloma or glioblastoma cancer cell lines. Advise patients taking bortezomib, not to take green tea.
Carbamazepine (Tegretol)
Theoretically, green tea might reduce the effects of carbamazepine and increase the risk for convulsions.
Green tea contains caffeine. Animal research suggests that taking caffeine can lower the anticonvulsant effects of carbamazepine and can induce seizures when taken in doses above 400 mg/kg. Human research has shown that taking caffeine 300 mg in three divided doses along with carbamazepine 200 mg reduces the bioavailability of carbamazepine by 32% and prolongs the plasma half-life of carbamazepine 2-fold in healthy individuals.
Celiprolol (Celicard)
Theoretically, green tea might reduce the levels and clinical effects of celiprolol.
In a small human study, taking green tea daily for 4 days appears to decrease blood and urine levels of celiprolol by at least 98%. This interaction is possibly due to the inhibition of organic anion transporting polypeptide (OATP). Green tea catechins have been shown to inhibit organic anion transporting polypeptides (OATP), one of which, OATP1A2, is found in the intestine The interaction is thought to be due primarily to the epigallocatechin gallate (EGCG) content of green tea.
Cimetidine (Tagamet)
Theoretically, concomitant use might increase the effects and adverse effects of caffeine in green tea.
Green tea contains caffeine. Cimetidine can reduce caffeine clearance by 31% to 42%.
Clozapine (Clozaril)
Theoretically, green tea might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Animal research suggests that, although green tea extract does not affect the elimination of clozapine, it delays the time to reach peak concentration and reduces the peak plasma levels. Also, concomitant administration of green tea and clozapine might theoretically cause acute exacerbation of psychotic symptoms due to the caffeine in green tea. Caffeine can increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg daily inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Researchers speculate that caffeine might inhibit CYP1A2. However, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients be more sensitive to the interaction between clozapine and caffeine.
Contraceptive Drugs
Theoretically, concomitant use might increase the effects and adverse effects of caffeine found in green tea.
Green tea contains caffeine. Oral contraceptives can decrease caffeine clearance by 40% to 65%.
Cytochrome P450 1A2 (Cyp1A2) Inhibitors
Theoretically, concomitant use might increase the levels and adverse effects of caffeine.
Green tea contains caffeine. Caffeine is metabolized by cytochrome P450 1A2 (CYP1A2),. Theoretically, drugs that inhibit CYP1A2 may decrease the clearance rate of caffeine from green tea and increase caffeine levels.
Dipyridamole (Persantine)
Theoretically, green tea might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Green tea contains caffeine. Caffeine might inhibit dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.
Disulfiram (Antabuse)
Theoretically, disulfiram might increase the risk of adverse effects from caffeine.
In human research, disulfiram decreases the clearance and increases the half-life of caffeine.
Diuretic Drugs
Theoretically, using green tea with diuretic drugs might increase the risk of hypokalemia.
Green tea contains caffeine. In excessive amounts, caffeine can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.
Estrogens
Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Green tea contains caffeine. Estrogen inhibits caffeine metabolism.
Ethosuximide (Zarontin)
Theoretically, green tea might reduce the effects of ethosuximide and increase the risk for convulsions.
Green tea contains caffeine. Animal research suggests that caffeine 92.4 mg/kg can decrease the anticonvulsant activity of ethosuximide. However, this effect has not been reported in humans.
Felbamate (Felbatol)
Theoretically, green tea might reduce the effects of felbamate and increase the risk for convulsions.
Green tea contains caffeine. Animal research suggests that a high dose of caffeine 161.7 mg/kg can decreases the anticonvulsant activity of felbamate. However, this effect has not been reported in humans.
Fexofenadine (Allegra)
Green tea can decrease blood levels of fexofenadine.
Clinical research shows that green tea can significantly decrease blood levels and excretion of fexofenadine. Taking green tea extract with a dose of fexofenadine decreased bioavailability of fexofenadine by about 30%. In vitro, green tea inhibits the cellular accumulation of fexofenadine by inhibiting the organic anion transporting polypeptide (OATP) drug transporter. Research shows that two of the major catechins found in green tea, epicatechin gallate (ECG) and epigallocatechin gallate (EGCG), inhibit OATPs, specifically OATP1A2, OATP1B1, and OATP2B1. In addition, green tea has been shown to reduce the absorption of some drugs that are OATP substrates.
Flutamide (Eulexin)
Theoretically, green tea might increase the levels and adverse effects of flutamide.
Green tea contains caffeine. In vitro evidence suggests that caffeine can inhibit the metabolism of flutamide. Theoretically, concomitant use of caffeine and flutamide might increase serum concentrations of flutamide and increase the risk adverse effects.
Fluvoxamine (Luvox)
Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Green tea contains caffeine. Fluvoxamine reduces caffeine metabolism.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Green tea extract supplements have been linked to several cases of hepatotoxicity and might have additive hepatotoxic effects with other drugs..
Imatinib (Gleevec)
Theoretically, green tea might reduce the levels and clinical effects of imatinib.
In animal research, a single dose of green tea extract reduces the area under the curve (AUC) of imatinib by up to approximately 64% and its main metabolite N-desmethyl imatinib by up to approximately 81%. This interaction has not been shown in humans. The mechanism of action is unclear but may involve multiple pathways.
Coenzyme Q10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Radiant Care 11:1, from the product label.
Get Healthy Again
See all Get Healthy Again products- Name
- Get Healthy Again
- Street Address
- 3281 Kachemak Drive
- City
- Homer
- State
- AK
- ZipCode
- 99603
- Phone Number
- 800.832.9755
- Web Address
- GetHealthyAgainStore.com
Radiant Care 11:1 by Get Healthy Again: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Radiant Care 11:1 is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Radiant Care 11:1’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Coenzyme Q10
Interacts with 198 drugsCoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...
Read the full Coenzyme Q10 monograph → Herb & supplement monographGreen Tea
Interacts with 1,293 drugsGreen tea is a popular beverage rich in antioxidants called catechins, and drinking it in normal amounts is considered safe for most people. Concentrated green tea extracts are a different s...
Read the full Green Tea monograph →Sources & How We Checked
Radiant Care 11:1's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 689 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Potassium 12 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
- Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
- Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
- Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
- Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
- Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
- Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
- Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
- Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
- Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
- Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
Lecithin 9 references
- Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
- Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
- Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
- Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
- Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
- Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
- Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:
Citric Acid 10 references
- Kurtzweil P. Alpha-hydroxy acids for skin care: Smooth sailing or rough seas? FDA 1999. Available at: /www.fda.gov/fdac/features/1998/298_ahas.html (Accessed 18 August 2000). DOI
- Erbagci Z, Akcali C. Biweekly serial glycolic acid peels vs. long-term daily use of topical low-strength glycolic acid in the treatment of atrophic acne scars. Int J Dermatol 2000;39:789-94.. PubMed
- Ghadishah D, Gorchynski J. Airway compromise after routine alpha-hydroxy facial peel administration. J Emerg Med 2002;22:353-5.. PubMed
- Baumann LS, Oresajo C, Yatskayer M, Dahl A, Figueras K. Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment
- Emtestam L, Svensson Å, Rensfeldt K. Treatment of seborrhoeic dermatitis of the scalp with a topical solution of urea, lactic acid, and propylene glycol (K301): results of two double-blind, randomised, placebo-controlled studies. Mycoses. 2012 Sep;55(5):3 PubMed
- Kaminaka C, Uede M, Matsunaka H, Furukawa F, Yamomoto Y. Clinical evaluation of glycolic acid chemical peeling in patients with acne vulgaris: a randomized, double-blind, placebo-controlled, split-face comparative study. Dermatol Surg. 2014 Mar;40(3):314- PubMed
- Köse O, Özmen I, Arca E. An open, comparative study of 10% potassium hydroxide solution versus salicylic and lactic acid combination in the treatment of molluscum contagiosum in children. J Dermatolog Treat. 2013 Aug;24(4):300-4. PubMed
- Vachiramon V, Sahawatwong S, Sirithanabadeekul P. Treatment of melasma in men with low-fluence Q-switched neodymium-doped yttrium-aluminum-garnet laser versus combined laser and glycolic acid peeling. Dermatol Surg. 2015 Apr;41(4):457-65. PubMed
- US Food and Drug Administration (FDA). Cosmetic Ingredients: Alpha Hydroxy Acids. August 2020. Available at: https://www.fda.gov/cosmetics/cosmetic-ingredients/alpha-hydroxy-acids. Accessed on October 19, 2021.
- Ormerod AD, van Voorst Vader PC, Majewski S, Vanscheidt W, Benjamin N, van der Meijden W. Evaluation of the efficacy, safety, and tolerability of 3 dose regimens of topical sodium nitrite with citric acid in patients with anogenital warts: A randomized cl DOI
Black Currant 6 references
- Guivernau M, Meza N, Barja P, Roman O. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. Prostaglandins Leukot Essent Fatty A PubMed
- Fa-lin Z, Zhen-yu W, Yan H, et al. Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment. Phytother Res 2010;24 Suppl 2:S209-13. PubMed
- Holman CP and Bell AF. A trial of evening primrose oil in the treatment of chronic schizophrenia. J Orhtomolecular Psych 1983;12:302-304.
- Vaddadi KS. The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. Prostaglandins Med 1981;6(4):375-379. PubMed
- Norred, C. L. and Brinker, F. Potential coagulation effects of preoperative complementary and alternative medicines. Alt Ther 2001;7(6):58-67.
- Puri BK. The safety of evening primrose oil in epilepsy. Prostaglandins Leukotrienes Essential Fatty Acids 2007;77:101-3. PubMed
Black Seed 60 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Aqel M, Shaheen R. Effects of the volatile oil of black seed seeds on the uterine smooth muscle of rat and guinea pig. J Ethnopharmacol 1996;52:23-6.
- Keshri G, Singh MM, Lakshmi V, Kamboj VP. Post-coital contraceptive efficacy of the seeds of Black seed in rats. Indian J Physiol Pharmacol 1995;39:59-62.
- Tennekoon KH, Jeevathayaparan S, Kurukulasooriya AP, Karunanayake EH. Possible hepatotoxicity of Nigella sativa seeds and Dregea volubilis leaves. J Ethnopharmacol 1991;31:283-9. PubMed
- Dehkordi FR, Kamkhah AF. Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension. Fundam Clin Pharmacol 2008;22:447-52.
- Zaoui, A., Cherrah, Y., Lacaille-Dubois, M. A., Settaf, A., Amarouch, H., and Hassar, M. [Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat]. Therapie 2000;55(3):379-382.
- Enomoto, S., Asano, R., Iwahori, Y., Narui, T., Okada, Y., Singab, A. N., and Okuyama, T. Hematological studies on black cumin oil from the seeds of Nigella sativa L. Biol.Pharm.Bull 2001;24(3):307-310. PubMed
- Meral, I., Yener, Z., Kahraman, T., and Mert, N. Effect of Nigella sativa on glucose concentration, lipid peroxidation, anti-oxidant defence system and liver damage in experimentally-induced diabetic rabbits. J Vet.Med A Physiol Pathol.Clin Med 2001;48(1
- Al Jishi, S. A. and Abuo, Hozaifa B. Effect of Nigella sativa on blood hemostatic function in rats. J Ethnopharmacol. 2003;85(1):7-14. PubMed
- Ali, B. H. and Blunden, G. Pharmacological and toxicological properties of Nigella sativa. Phytother.Res. 2003;17(4):299-305.
- Al Naggar, T. B., Gomez-Serranillos, M. P., Carretero, M. E., and Villar, A. M. Neuropharmacological activity of Nigella sativa L. extracts. J Ethnopharmacol. 2003;88(1):63-68. PubMed
- Kalus, U., Pruss, A., Bystron, J., Jurecka, M., Smekalova, A., Lichius, J. J., and Kiesewetter, H. Effect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseases. Phytother.Res. 2003;17(10):1209-1214.
- Islam, S. N., Begum, P., Ahsan, T., Huque, S., and Ahsan, M. Immunosuppressive and cytotoxic properties of Nigella sativa. Phytother.Res. 2004;18(5):395-398.
- Fararh, K. M., Atoji, Y., Shimizu, Y., Shiina, T., Nikami, H., and Takewaki, T. Mechanisms of the hypoglycaemic and immunopotentiating effects of Nigella sativa L. oil in streptozotocin-induced diabetic hamsters. Res Vet.Sci 2004;77(2):123-129. PubMed
- Awad, E. M. and Binder, B. R. In vitro induction of endothelial cell fibrinolytic alterations by Nigella sativa. Phytomedicine 2005;12(3):194-202. PubMed
- El Obeid, A., Al Harbi, S., Al Jomah, N., and Hassib, A. Herbal melanin modulates tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) production. Phytomedicine. 2006;13(5):324-333.
- Abbas, A. T., Abdel-Aziz, M. M., Zalata, K. R., and Tel, Abd Al-Galel. Effect of dexamethasone and Nigella sativa on peripheral blood eosinophil count, IgG1 and IgG2a, cytokine profiles and lung inflammation in murine model of allergic asthma. Egypt J Im
- Kaleem, M., Kirmani, D., Asif, M., Ahmed, Q., and Bano, B. Biochemical effects of Nigella sativa L seeds in diabetic rats. Indian J Exp.Biol. 2006;44(9):745-748.
- Hawsawi, Z. A., Ali, B. A., and Bamosa, A. O. Effect of Nigella sativa (Black Seed) and thymoquinone on blood glucose in albino rats. Ann.Saudi Med 2001;21(3-4):242-244.
- Massadeh, A. M., Al Safi, S. A., Momani, I. F., Al Mahmoud, M., and Alkofahi, A. S. Analysis of cadmium and lead in mice organs: effect of Nigella sativa L. (Black Cumin) on the distribution and immunosuppressive effect of cadmium-lead mixture in mice. B PubMed
- Akhondian, J., Parsa, A., and Rakhshande, H. The effect of Nigella sativa L. (black cumin seed) on intractable pediatric seizures. Med Sci Monit. 2007;13(12):CR555-CR559.
- Meddah, B., Ducroc, R., El Abbes, Faouzi M., Eto, B., Mahraoui, L., Benhaddou-Andaloussi, A., Martineau, L. C., Cherrah, Y., and Haddad, P. S. Nigella sativa inhibits intestinal glucose absorption and improves glucose tolerance in rats. J Ethnopharmacol. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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